QSAR modeling of benzoquinone derivatives as 5-lipoxygenase inhibitors by T.K. Shameera Ahamed, Vijisha K. Rajan, K. Muraleedharan

“…The inhibitors of 5-LOX control the overproduction of pro-inflammatory mediators known as leukotrienes (LTs) and thus have therapeutic relevance in the treatment of various diseases like asthma, rheumatoid arthritis, inflammatory bowel disease and certain types of cancers. This has increased the search for efficient therapeutic agents for protein 5-LOX and this process is now primarily based on QSAR. …”
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How Bacteria-Induced Apoptosis of Intestinal Epithelial Cells Contributes to Mucosal Inflammation by Martin Hausmann

“…But increased permeability of the epithelial barrier and increased apoptotic rates of epithelial cells have been reported for patients suffering from inflammatory bowel disease. Microbiota can both induce or inhibit apoptosis of intestinal epithelial cells thus contribute to mucosal inflammation or support epithelial integrity respectively. …”
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Primary sclerosing cholangitis by Marina G Silveira, Keith D Lindor

“…PSC primarily affects young and middle-aged men, often in association with underlying inflammatory bowel disease. The etiology of PSC includes immune-mediated components and elements of undefined nature. …”
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Malakoplakia associated with diarrhoea and colonic lesions after rituximab treatment by Yaqoub Alshatti, Meshaan Alenezi

“…Malakoplakia is a rare granulomatous condition that occurs due to defective lysosomal digestion during phagocytosis and can mimic inflammatory bowel disease (IBD) or malignancies, particularly in immunosuppressed patients. …”
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The Role of Combining Probiotics in Preventing and Controlling Inflammation: A Focus on the Anti-Inflammatory and Immunomodulatory Effects of Probiotics in an In Vitro Model of IBD by Shadi Aghamohammad, Amin Sepehr, Seyedeh Tina Miri, Saeideh Najafi, Mohammad R. Pourshafie, Mahdi Rohani

“…The use of probiotics could be considered as an appropriate complementary treatment for patients with inflammatory bowel disease.…”
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Zebrafish as a model for human epithelial pathology by Ahmed Abu-Siniyeh, Moayad Khataibeh, Walid Al-Zyoud, Majed Al Holi

“…Zebrafish possess significant cellular and functional homology with mammals, which facilitates the investigation of various diseases, including inflammatory bowel disease, nonalcoholic fatty liver disease, and polycystic kidney disease. …”
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Atractylenolide III Improves Mitochondrial Function and Protects Against Ulcerative Colitis by Activating AMPK/SIRT1/PGC-1α by Jieru Han, Wenhao Li, Guangyu Shi, Yunlei Huang, Xutao Sun, Na Sun, Deyou Jiang

“…Ulcerative colitis (UC) is a complex inflammatory bowel disease (IBD) associated with mitochondrial function. …”
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Anti-inflammatory actions of acupuncture by Freek J. Zijlstra, Ineke van den Berg-de Lange, Frank J. P. M. Huygen, Jan Klein

“…The attributive effect of acupuncture has been investigated in inflammatory diseases, including asthma, rhinitis, inflammatory bowel disease, rheumatoid arthritis, epicondylitis, complex regional pain syndrome type 1 and vasculitis. …”
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Henoch-Schönlein Purpura with Adalimumab Therapy for Ulcerative Colitis: A Case Report and Review of the Literature by Joseph J. LaConti, Jean A. Donet, Jeong Hee Cho-Vega, Daniel A. Sussman, Dana Ascherman, Amar R. Deshpande

“…Tumor necrosis factor-α (TNFα) inhibitor therapy has signified an important milestone in the fight against many rheumatological disorders and inflammatory bowel disease (IBD). Cutaneous adverse events caused by this class of medications are well known but relatively uncommon. …”
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Bach2: A Key Regulator in Th2-Related Immune Cells and Th2 Immune Response by Guo Liu, Feng Liu

“…Genome-wide association studies have identified various susceptibility loci of Bach2 which are linked with Th2 inflammatory diseases such as asthma and inflammatory bowel disease. Here, we discuss the critical role of Bach2 involved in the Th2 immune response and associated inflammatory diseases.…”
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Iron Deficiency Anaemia Caused by Nonspecific (Idiopathic) Small Bowel Ulceration: An Uncommon Presentation of an Uncommon Disease by Gabriele Capurso, Edith Lahner, Nadia Pallotta, Francesco Panzuto, Gianfranco Delle Fave, Bruno Annibale

“…Ulcers of the small bowel are rare, and in most cases are due to infections, inflammatory bowel diseases, malignancies or drugs. When none of these causes is recognized, they are classified as ‘nonspecific’ or idiopathic. …”
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Functional Analysis of Monkeypox and Interrelationship between Monkeypox and COVID-19 by Bioinformatic Analysis by Eun Jung Sohn

“…KEGG analysis of 212 DEGs of GSE36854 and GSE21001 for monkeypox infection showed involvement of monkeypox in COVID-19, cytokine-cytokine receptor interaction, inflammatory bowel disease, atherosclerosis, TNF signaling, and T cell receptor signaling. …”
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Estimation of salivary IL-6 and calprotectin in patients with ulcerative colitis by Fadhel A. Abdullah, Maha A. Mahmood

“… Inflammatory bowel disease (IBD) is chronic inflammation of the gastrointestinal tract (GIT) it includes two-condition Crohn’s disease (CD) and ulcerative colitis (UC) the prolonged inflammation may cause invasion of the multiple layers of the intestinal walls result in GIT damage. …”
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Case report: A co-existing case of ulcerative colitis and dysferlinopathy in a male patient by Limin Li, Qiong Yan, Mingming Deng, Muhan Lü, Tiejun Zhou, Xiaolin Zhong

“…Patients with inflammatory bowel disease (IBD) are at risk of developing malnutrition, severe dystrophic muscle weakness, and muscle atrophy. …”
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The Role of IL-33 in Gut Mucosal Inflammation by Luca Pastorelli, Carlo De Salvo, Maurizio Vecchi, Theresa T. Pizarro

“…In 2010, four different research groups consistently described the upregulation of IL-33 in patients with inflammatory bowel disease (IBD). Animal models of IBD were subsequently utilized in order to mechanistically determine the precise role of IL-33 in chronic intestinal inflammation, without, however, reaching conclusive evidence demonstrating whether IL-33 is pathogenic or protective. …”
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The Impact of PPARγ Genetic Variants on IBD Susceptibility and IBD Disease Course by Jessica Mwinyi, Christa Grete-Wenger, Jyrki J. Eloranta, Gerd A. Kullak-Ublick

“…We aimed at determining the occurring PPARγ SNPs, at predicting the haplotypes, and at determining the frequency outcome in inflammatory bowel disease (IBD) patients in comparison with healthy controls. …”
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Clinical Onset of Celiac Disease after an Episode of Campylobacter jejuni Enteritis by EF Verdu, M Mauro, J Bourgeois, D Armstrong

“…Infectious gastroenteritis is a well-established risk factor for the development of IBS, and there is recent evidence that it could play a role in the initiation and exacerbation of inflammatory bowel disease. The present case suggests that the clinical expression of CD can be unmasked by an acute gastrointestinal infection and supports the hypothesis that environmental factors other than gliadin may play a role in the clinical onset of CD in a genetically susceptible host. …”
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A Burkitt's Lymphoma Case Mimicking Crohn's Disease: A Case Report by Gulbanu Erkan, Mehmet Çoban, Aysun Çalıskan, Gokçe Kaan Ataç, Kamil Gulpınar, Bulent Degertekin, Atilla Korkmaz

“…Particularly gastrointestinal lymphomas can be clinically confused with other gastrointestinal tumors as well as with diffuse and inflammatory bowel disease. Early diagnosis and treatment bear vital importance in the management of lymphomas due to their high proliferation rates. …”
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The Role of Th17 Cells and IL-17 in Th2 Immune Responses of Allergic Conjunctivitis by Xiang-Tian Meng, Yun-Yue Shi, Hong Zhang, Hong-Yan Zhou

“…Studies have shown that Th17 cells are involved in a variety of immune inflammation, including psoriasis, rheumatoid arthritis, inflammatory bowel disease, systemic lupus erythematosus, and asthma. …”
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Antigen Presentation in the Gut by W Doe, P Pavli

“…Taken together, the aberrant expression of class II MHC molecules, breaches in epithelial cell integrity (resulting m exposure to luminal antigens including endotoxin and the increased numbers of monocytes found 10 inflamed mucosa suggest that the resulting distortions in antigen presentation contribute to the localization and persistence of the inflammatory lesion in inflammatory bowel disease.…”
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