Comment on “Biomarkers as Potential Treatment Targets in Inflammatory Bowel Disease: A Systematic Review” by Nicholas-Paul Delicata, Neville Azzopardi, Pierre Ellul

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Lupus-Like Syndrome Caused by 5-Aminosalicylic Acid in Patients with Inflammatory Bowel Disease by Andrew W Kirkpatrick, Arthur A Bookman, Flavio Habal

“…BACKGROUND: Although 5-aminosalicylic acid (5-ASA) preparations used to treat inflammatory bowel disease are reported to have fewer side effects than sulphasalazine, increased clinical use of these compounds has resulted in increased reports of significant side effects.…”
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Mesalazine-Induced Acute Pancreatitis in Inflammatory Bowel Disease Patients: A Systematic Review by Pan J, Li Z, Ye C, Zhang X, Yang Q, Zhang X, Zhou Y, Zhang J

“…Juan Pan,1,* Zuyi Li,1,* Chao Ye,2 Xiaojuan Zhang,1 Qiongliang Yang,1 Xu Zhang,1 Ya Zhou,3 Jianjun Zhang2 1Department of Pharmacy, Liuyang Hospital of Traditional Chinese Medicine, Changsha, Hunan, 410300, People’s Republic of China; 2Department of Pharmacy, Guangdong Provincial second Hospital of Traditional Chinese Medicine (Guangdong Provincial Engineering Technology Research Institute of Traditional Chinese Medicine), Guangzhou, Guangdong, 510095, People’s Republic of China; 3Department of Pharmacy, People’s Hospital of Ningxiang City Affiliated to Hunan University of Chinese Medicine, Changsha, Hunan, 410600, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chao Ye, Department of Pharmacy, Guangdong Provincial second Hospital of Traditional Chinese Medicine (Guangdong Provincial Engineering Technology Research Institute of Traditional Chinese Medicine), No. 60, Hengfu Road, Guangzhou, Guangdong, 510095, People’s Republic of China, Email yechao1234256@163.comObjective: Mesalazine is a widely used medication for treating mild to moderate inflammatory bowel disease (IBD). First identified as a potential cause of acute pancreatitis (AP) in 1989, the link between mesalazine and AP has primarily been established through case reports and a limited number of retrospective studies. …”
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Mesenchymal Stem Cell-derived Exosomes: Novel Therapeutic Approach for Inflammatory Bowel Diseases by Cheng-mei Tian, Mei-feng Yang, Hao-ming Xu, Min-zheng Zhu, Yuan Zhang, Jun Yao, Li-sheng Wang, Yu-jie Liang, De-feng Li

“…The anti-inflammatory and immunomodulatory activities of mesenchymal stem cell (MSC)-derived Exos (MSC-Exos) provide a rationale for novel cell-free therapies for inflammatory bowel disease (IBD). Growing evidence has shown that MSC-Exos can be a potential candidate for treating IBD. …”
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Intestinal inflammation in TNBS sensitized rats as a model of chronic inflammatory bowel disease by N. Selve, T. Wöhrmann

“…The applicability and relevance of this new model are discussed with respect to drug development and basic research of inflammatory bowel diseases.…”
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The Utility of Fecal Calprotectin in the Real-World Clinical Care of Patients with Inflammatory Bowel Disease by Esmail Abej, Wael El-Matary, Harminder Singh, Charles N. Bernstein

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Therapeutic application and potential mechanism of plant-derived extracellular vesicles in inflammatory bowel disease by Jinling Li, Ting Luo, Dou Wang, Yao Zhao, Yuanxiang Jin, Guiling Yang, Xin Zhang

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Causal relationship between inflammatory bowel disease and sex: a Mendelian randomization study by Kaiwen Wang, Yu Lou, Shunjie Tian, Zhihui Tao, Zhihui Tao

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Assessment tools for transition readiness in adolescents with inflammatory bowel disease: A scoping review by YaHui Zuo, Mei Li, JinJin Cao, JiaNan Wang, WenQian Cai, Lu Zhang, Meng Li

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Predictors of Medication Adherence in Pediatric Inflammatory Bowel Disease Patients at the Stollery Children’s Hospital by L Kitney, JM Turner, D Spady, B Malik, W El-Matary, R Persad, HQ Huynh

“…BACKGROUND: Patients with inflammatory bowel disease (IBD) often do not take their medications as prescribed.…”
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Antineoplastic Effects of 5-Aminosalicylates and Potential Cancer Preventive Role in Inflammatory Bowel Disease by Hugh J Freeman

“…Early studies from tertiary referral centers in the United States and Europe showed that patients with long-standing and extensive inflammatory bowel disease (IBD) have an increased risk of colon cancer. …”
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Novel immune cross-talk between inflammatory bowel disease and IgA nephropathy by Qianqian Yan, Zihao Zhao, Dongwei Liu, Jia Li, Shaokang Pan, Jiayu Duan, Zhangsuo Liu

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Clinical Outcomes of COVID-19 and Impact on Disease Course in Patients with Inflammatory Bowel Disease by Panu Wetwittayakhlang, Farah Albader, Petra A Golovics, Gustavo Drügg Hahn, Talat Bessissow, Alain Bitton, Waqqas Afif, Gary Wild, Peter L Lakatos

“…The impact of COVID-19 has been of great concern in patients with inflammatory bowel disease (IBD) worldwide, including an increased risk of severe outcomes and/or possible flare of IBD. …”
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Topical steroids as alternative to systemic hormonal treatment for inflammatory bowel diseases in pediatric practice by E. N. Fedulova, O. V. Shumilova, O. V. Fedorova, O. A. Tutina, G. V. Medyantseva

“…To share experience of application of topical steroids (Budenofalk®) in children with hormone – dependent inflammatory bowel diseases (IBD) and severe side effects on a background of systemic corticosteroids (CS).Original positions. …”
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Thiamine-Reduced Fatigue in Quiescent Inflammatory Bowel Disease Is Linked to Faecalibacterium prausnitzii Abundance by Sandra Bermúdez-Sánchez, Palle Bager, Jens Frederik Dahlerup, Simon Mark Dahl Baunwall, Tine Rask Licht, Martin Steen Mortensen, Christian Lodberg Hvas

“…Background and Aims: Chronic fatigue is common in patients with inflammatory bowel disease (IBD). The gut microbiota, specifically, microbial diversity and butyrate-producing bacteria have been linked to the fatigue pathogenesis. …”
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Should We Establish Standards of Care for Management of Elderly Patients with Inflammatory Bowel Disease? by Subrata Ghosh, Marietta Iacucci

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Increased urinary nitrite, a marker of nitric oxide, in active inflammatory bowel disease by Michael G. Goggins, Syed A. Shah, Jason Goh, Anil Cherukuri, Donal G. Weir, Dermot Kelleher, Nasir Mahmud

“…Background: Nitric oxide (NO) production is increased in inflammatory bowel disease (IBD), and measurement of NO metabolites may be useful for monitoring disease activity.…”
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Effects of Formal Education for Patients with Inflammatory Bowel Disease: A Randomized Controlled Trial by Barbara M Waters, Louise Jensen, Richard N Fedorak

“…BACKGROUND: Patients with inflammatory bowel disease (IBD) suffer physical dysfunction and impaired quality of life (QOL), and need frequent health care. …”
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Apical periodontitis in inflammatory bowel disease: a meta-analysis at patient and tooth level by Giusy Rita Maria La Rosa, Alejandro Ismael Lorenzo-Pouso, Vito Carlo Alberto Caponio, Mariangela Valentina Puci, Mariangela Valentina Puci

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Anti-TNF-α Therapy Suppresses Proinflammatory Activities of Mucosal Neutrophils in Inflammatory Bowel Disease by Cui Zhang, Weigang Shu, Guangxi Zhou, Jian Lin, Feifei Chu, Huili Wu, Zhanju Liu

“…Neutrophils have been found to play an important role in the pathogenesis of inflammatory bowel disease (IBD), and anti-TNF-α mAb (i.e., infliximab) therapy is demonstrated to be effective in the induction of clinical remission and mucosal healing in these patients. …”
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