Methotrexate: ‘Lessons from Rheumatology’ by Remo Panaccione

Get full text

Mechanism of action of 5-arninosalicylic acid by N. A. Punchard, S. M. Greenfield, R. P. H. Thompson

“…5-Aminosalicylic Acid (5-ASA) has been used for over 50 years in the treatment of inflammatory bowel disease in the pro-drug form sulphasalazine (SASP). …”
Get full text

Epidemiology and Treatment Patterns of Fistulizing Crohn’s Disease in a Large, Real-World Australasian Cohort by Jack McNamara, William Wilson, Joseph L. Pipicella, Simon Ghaly, Jakob Begun, Ian C. Lawrance, Richard Gearry, Jane M. Andrews, Susan J. Connor

“…Methods: A large real-world cohort of people with inflammatory bowel disease under routine care was interrogated in August 2023. …”
Get full text

Mesalazine-Induced Myopericarditis in a Patient with a Recent Diagnosis of Crohn’s Disease: Apropos of a Case by Michele Sorleto, Stefanie Dürrwald, Marcus Wiemer

“…Mesalazine- (5-aminosalicylic acid-) containing products are a well-known treatment for inflammatory bowel disease, often as first line. Myocarditis is recognized as a very rare possible side effect of this drug treatment. …”
Get full text

A Practical Review of Cytomegalovirus in Gastroenterology and Hepatology by Ali Y. Fakhreddine, Catherine T. Frenette, Gauree G. Konijeti

“…This review will focus on the pathophysiology, diagnosis, and management of CMV in patient populations relevant to the practice of gastroenterology and hepatology—liver transplant recipients, inflammatory bowel disease patients, and otherwise immunocompetent patients.…”
Get full text

New-Onset Ulcerative Colitis in a Young Caucasian Woman with Unclassified Arteritis by Bryan Roberts

“…Cases have been reported in patients with inflammatory bowel disease, suggesting possible genetic linkage. …”
Get full text

Cerebral Arterial Thrombosis in Ulcerative Colitis by Giovanni Casella, Claudio Camillo Cortelezzi, DeLodovici Marialuisa, Princiotta Cariddi Lucia, Verrengia Elena Pinuccia, Vittorio Baldini, Sergio Segato

“…Thrombosis, mainly venous, is a rare and well-recognized extraintestinal manifestation of inflammatory bowel disease (IBD). We describe a 25-year-old Caucasian man affected by ulcerative colitis and sclerosing cholangitis with an episode of right middle cerebral arterial thrombosis resolved by intraarterial thrombolysis. …”
Get full text

Giant Cell Myocarditis in a Patient With Crohn's Disease, Treated with Etanercept – A Tumour Necrosis Factor-Alpha Antagonist by C Nash, R Panaccione, LR Sutherland, JB Meddings

“…Cardiac disease in association with inflammatory bowel disease (IBD) is uncommon. Reports include pericarditis, pericardial effusion, myocarditis, myocardial infarction, endocarditis and arrythmias. …”
Get full text

Reactive Lymphoid Hyperplasia of the Liver Incidentally Found in a 55-Year-Old Woman with a History of Ulcerative Colitis by Noritoshi Mizuta, Takuya Kikuchi, Shunsuke Kusano, Nobuya Sano

“…No case was reported in association with inflammatory bowel disease. We report a case of RLH of the liver in a patient with ulcerative colitis (UC). …”
Get full text

Unique quantitative electroencephalography differences and related behavioral dynamics in Crohn’s disease by Yihan Zhuang, Hairu Yang, Xinyi Huang, Guanghua Guo, Quan Shi, Yiting Lin, Wenwen Xue, Zeyu Huang, Sisi Zhou, Jiahui Cai, Haizhu Tan, Jing Yu

“…Crohn's disease (CD) is a major type of inflammatory bowel disease (IBD) characterized by idiopathic, chronic inflammation with a patchy transmural inflammatory pattern. …”
Get full text

Highlights in IBD Epidemiology and Its Natural History in the Paediatric Age by Marco Gasparetto, Graziella Guariso

“…The number of patients of all age brackets diagnosed with Inflammatory Bowel Disease (IBD) has risen dramatically worldwide over the past 50 years. …”
Get full text

Effects of Anti-Cytokine Antibodies on Gut Barrier Function by Fang Liu, Seul A. Lee, Stephen M. Riordan, Li Zhang, Lixin Zhu

“…Anti-cytokine antibodies are used in treating chronic inflammatory diseases and autoimmune diseases such as inflammatory bowel disease and rheumatic diseases. Patients with these diseases often have a compromised gut barrier function, suggesting that anti-cytokine antibodies may contribute to the re-establishment of gut barrier integrity, in addition to their immunomodulatory effects. …”
Get full text

Multifocal Multisystem Langerhans Cell Histiocytosis Involving Pituitary Masquerading as Crohn’s Disease: A Case Report and Review of the Literature by Mohd. Ashraf Ganie, Bhanu Malhotra, Manpreet Saini, Arshiya Dutta, Atul Sharma, Kim Vaiphie, Pinaki Dutta

“…We present a case of Langerhans cell histiocytosis (LCH) with gastrointestinal involvement masquerading as inflammatory bowel disease (IBD) in a patient who initially had features of central diabetes insipidus (CDI). …”
Get full text

Gastroduodenal Ulcerative Colitis in Association with Ulcerative Pancolitis by Khin San Aye, Lin Lin Htun, Thet Mar Win, Mya Thida Aye, Drmyothettin Tin, Than Than Aye

“…Ulcerative colitis (UC) is a chronic inflammatory bowel disease, traditionally regarded as being limited to the colorectum. …”
Get full text

Correlation of Patient-Reported Outcome (PRO-2) with Endoscopic and Histological Features in Ulcerative Colitis and Crohn’s Disease Patients by Sanja Dragasevic, Aleksandra Sokic-Milutinovic, Milica Stojkovic Lalosevic, Tamara Milovanovic, Srdjan Djuranovic, Ivan Jovanovic, Sanja Rajic, Mirjana Stojkovic, Biljana Milicic, Stefan Kmezic, Branislav Oluic, Marko Aleksic, Aleksandra Pavlovic Markovic, Dragan Popovic

“…Determination of inflammatory bowel disease activity determines further therapeutic approach and follow-up. …”
Get full text

Colonic Squamous Cell Carcinoma in Ulcerative Colitis: Report of a Case and Review of the Literature by Huilan Cheng, Michael D Sitrin, Sateesh K Satchidanand, Jan M Novak

“…Related literature on colorectal SCC and squamous metaplasia, and their relationships with inflammatory bowel disease and human papilloma virus, is reviewed.…”
Get full text

A Rare Case of New-Onset Ulcerative Colitis following Initiation of Secukinumab by Ted George Achufusi, Prateek S. Harnee, Sekou Rawlins

“…Recently, there has been increasing controversy regarding potential adverse effects of the drug especially in those with underlying inflammatory bowel disease. We present the case of a young male patient who developed severe new-onset ulcerative colitis following initiation of secukinumab for psoriasis, with excellent response and rapid resolution of symptoms with infliximab.…”
Get full text

Ketotifen Treatment of Active Colitis in Patients with 5-Aminosalicylate Intolerance by John K Marshall, E Jan Irvine

“…Although the role of mucosal mast cells in the pathogenesis of inflammatory bowel disease remains uncertain, mast cell stabilizers have been shown in animal models to attenuate the severity of experimental colitis. …”
Get full text

South African Rheumatism and Arthritis Association 2024 guidelines for the management of peripheral spondyloarthritis by R Benitha, A B Maharaj, K Makan, J Potts, A Lai, R Carter, M van Dam, B Hodkinson

“… Peripheral spondyloarthritis (SpA) includes psoriatic arthritis (PsA), inflammatory bowel disease (IBD)-associated arthritis, reactive arthritis and undifferentiated peripheral SpA. …”
Get full text

TRPV Subfamily (TRPV2, TRPV3, TRPV4, TRPV5, and TRPV6) Gene and Protein Expression in Patients with Ulcerative Colitis by Joel J. Toledo Mauriño, Gabriela Fonseca-Camarillo, Janette Furuzawa-Carballeda, Rafael Barreto-Zuñiga, Braulio Martínez Benítez, Julio Granados, Jesus K. Yamamoto-Furusho

Get full text