Inflammasome in Intestinal Inflammation and Cancer by Tiago Nunes, Heitor S. de Souza

“…In this review, we discuss the molecular structure, the mechanisms behind the inflammasome activation, and its possible role in the pathogenesis of inflammatory bowel diseases and intestinal cancer. Here, we show that the available data points towards the importance of the inflammasome in the innate intestinal immune response, being the complex involved in the maintenance of intestinal homeostasis, correct intestinal barrier function and efficient elimination of invading pathogens.…”
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Discussion of irritable bowel syndrome issue and functional constipations in reports of the 21st United European Gastroenterological Week (Berlin, 2013) by A. A. Sheptulin, M. A. Vizye-Khripunova

“…Differential diagnostics of IBS with other diseases (celiac sprue, chronic inflammatory bowel diseases, et al.), that may progress under a mask of the functional intestinal disorders is required. …”
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Interleukin-23 and Th17 Cells in the Control of Gut Inflammation by Ivan Monteleone, Francesco Pallone, Giovanni Monteleone

“…Crohn's Disease and Ulcerative Colitis, the major forms of inflammatory bowel diseases (IBDs) in humans, have been traditionally associated with exaggerated and poorly controlled T helper (Th) type 1 or Th2 cell response, respectively. …”
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Diagnostic Difficulties in Woman with Crohn’s Disease, Ascites, and Elevated Value of Serum CA125 Antigen by Maria Kłopocka, Ariel Liebert, Joanna Bielińska, Marcin Manerowski

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Synchronous Occurrence of Collagenous and Pseudomembranous Colitis by Z Vesoulis, G Lozanski, T Loiudice

“…Collagenous colitis has been reported in association with other inflammatory bowel diseases, including lymphocytic colitis, sprue and idiopathic inflammatory bowel disease. …”
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Review of Rome-IV criteria for the irritable bowel syndrome: are there any basic changes? by A. A. Sheptulin, M. A. Vize-Khripunova

“…As in the previous version, it is recommended to estimate compliance of the patient’s symptoms to Rome criteria, though it is noted that IBS-like clinical symptoms may be attributed to other diseases (celiac sprue, chronic inflammatory bowel diseases etc.). It causes the need of the limited laboratory and instrumental investigation of the patients. …”
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Blowhole Colostomy for Clostridium difficile-Associated Toxic Megacolon by Jeroen Kerstens, Ian Diebels, Charles de Gheldere, Patrick Vanclooster

“…After presenting our case, we discuss the literature available on the subject to argue that the scarce evidence on the optimal surgical treatment for TM is primarily based on TM associated with inflammatory bowel diseases (IBD) and that there might be a rationale for considering minimally invasive procedures like blowhole colostomy for CDI-associated TM.…”
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Eosinophilic Enteritis with Ascites in a Patient with Overlap Syndrome by Spyros Aslanidis, Athina Pyrpasopoulou, Kostas Soufleris, Eirini Kazantzidou, Stella Douma

“…Diagnosis can be problematic, as several other clinical conditions (malignancies, infection/tuberculosis, and inflammatory bowel diseases) have to be ruled out. It is basically a nonsurgical disease, with excellent recovery on conservative treatment. …”
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New perspectives on probiotics in health and disease by Eric Banan-Mwine Daliri, Byong H. Lee

“…Correlations between changes in composition and activity of the gut microbiota and common disorders such as cancer, hypertension, hypercholesterolemia, inflammatory bowel diseases, obesity, oral health, etc. have been proposed. …”
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Transcriptional Regulators of Claudins in Epithelial Tight Junctions by Niamat Khan, Abdul R. Asif

“…Altered function of claudins is implicated in different form of cancers, inflammatory bowel diseases (IBDs), and leaky diarrhea. Based on their significant role in the molecular architecture of TJ, diversity, and disease association, further understanding about claudin family proteins and their genetic/epigenetic regulators is indispensable.…”
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Crosstalk between the Intestinal Virome and Other Components of the Microbiota, and Its Effect on Intestinal Mucosal Response and Diseases by Njinju Asaba Clinton, Sodiq Ayobami Hameed, Eugene Kusi Agyei, Joy Chinwendu Jacob, Victor Oyewale Oyebanji, Cyril Ekabe Jabea

“…Finally, we elucidate the potential contribution of this crosstalk in the pathogenesis of inflammatory bowel diseases and colon cancer.…”
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Antimicrobial Peptides in Gastrointestinal Inflammation by Simon Jäger, Eduard F. Stange, Jan Wehkamp

“…The role of antimicrobial peptides in the primary events of inflammatory bowel diseases receives special attention.…”
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Colonic Mucosal Epigenome and Microbiome Development in Children and Adolescents by R. Alan Harris, Rajesh Shah, Emily B. Hollister, Rune Rose Tronstad, Nils Hovdenak, Reka Szigeti, James Versalovic, Richard Kellermayer

“…Epigenetic and microbiome changes during pediatric development have been implicated as important elements in the developmental origins of inflammatory bowel diseases (IBDs) including Crohn’s disease (CD) and ulcerative colitis (UC), which are linked to early onset colorectal cancer (CRC). …”
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The Potential of Food Protein-Derived Bioactive Peptides against Chronic Intestinal Inflammation by Wanying Zhu, Liying Ren, Li Zhang, Qinqin Qiao, Muhammad Zahid Farooq, Qingbiao Xu

“…Inflammation can cause various chronic diseases like inflammatory bowel diseases. Various food protein-derived bioactive peptides (BAPs) with anti-inflammatory activity have the potential to manage these diseases. …”
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Regulated Spatial Distribution of Cyclooxygenases and Lipoxygenases in Crohn's Ulcer

“…Arachidonic acid metabolism actively participates in the initiation, climaxing, and resolution phases of inflammation, and its close connection with inflammatory bowel diseases has been only recently discovered. …”
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Pathogenetic Aspects of Oral Cavity Lesions in Inflammatory Gastrointestinal Tract Diseases by N. S. Robakidze, O. B. Shchukina

“…Despite the extensive symptoms of oral manifestations of inflammatory bowel disease, aphthous stomatitis is considered more often than other diseases. …”
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Inside the mucosal immune system. by Jerry R McGhee, Kohtaro Fujihashi

“…Likewise, genetic background and environmental microbial encounters can lead to inflammatory bowel diseases (IBDs). This mucosal immune system (MIS) in both health and disease is currently under intense investigation worldwide by scientists with diverse expertise and interests. …”
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Amyloid Goiter Secondary to Ulcerative Colitis by Bunyamin Aydin, Yavuz Savas Koca, Tugba Koca, Ihsan Yildiz, Sevda Gerek Celikden, Metin Ciris

“…Secondary amyloidosis is rarely caused by inflammatory bowel diseases. Secondary amyloidosis is relatively more common in the patients with Crohn’s disease, whereas it is highly rare in patients with ulcerative colitis. …”
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Multi-detector computer tomography as effective method for Crohn's disease diagnostics by A. A. Tikhonov, A. V. Gorinov, I. V. Zarodnyuk, I. L. Khalif, Ye. S. Korolevsky

“…Improvement of diagnostics and efficacy of radiological methods of investigation by technique computer-tomography (CT) enterography at inflammatory bowel diseases.Material and methods. Original investigation was based on the data of comprehensive clinical and instrumental investigation of 111 patients with suspected Crohn's disease (CD). …”
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Interkingdom signaling between gastrointestinal hormones and the gut microbiome by Xinyu Zhao, Ye Qiu, Lanfan Liang, Xiangsheng Fu

“…Interventions leveraging the interplay between the gut microbiota and gastrointestinal hormones have been employed in the clinical management of metabolic diseases and inflammatory bowel diseases, such as bariatric surgery and fecal microbiota transplantation, offering promising targets for the treatment of dysbiosis-related diseases.…”
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