Decrease in HBsAg After TAF Switching from Entecavir During Long-Term Treatment of Chronic Hepatitis B Virus Infection by Kazuto Tajiri, Yuka Hayashi, Aiko Murayama, Nozomu Muraishi, Masami Minemura, Ichiro Yasuda

“…Switching from ETV to TAF is an effective strategy in CHB management, with hepatic inflammation potentially playing an essential role in achieving HBsAg decrease. …”
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Predicting the Progress of Tuberculosis by Inflammatory Response-Related Genes Based on Multiple Machine Learning Comprehensive Analysis by Shuai Ma, Peifei Peng, Zhihao Duan, Yifeng Fan, Xinzhi Li

“…Three machine learning models, namely LASSO, RF, and SVM-RFE, were used to identify the key characteristic genes related to inflammation during the progression of LTBI to ATB. The expression and diagnostic accuracy of these characteristic genes were subsequently verified. …”
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Prevention of Cardiovascular Disease: Screening for Magnesium Deficiency by Paolo Severino, Lucrezia Netti, Marco Valerio Mariani, Annalisa Maraone, Andrea D’Amato, Rossana Scarpati, Fabio Infusino, Mariateresa Pucci, Carlo Lavalle, Viviana Maestrini, Massimo Mancone, Francesco Fedele

“…Moreover, magnesium participates in inflammation and oxidative processes. In fact, magnesium deficiency is involved in the pathophysiology of arterial hypertension, diabetes mellitus, dyslipidemia, metabolic syndrome, endothelial dysfunction, coronary artery disease, cardiac arrhythmias, and sudden cardiac death. …”
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Synovial biomarkers in the diagnosis of post-traumatic osteoarthritis following anterior cruciate ligament and meniscus injuries: protocol for a systematic review by Helena Donato, Fernando Fonseca, João Pedro Oliveira, João Castro Mendes, José Casanova, Alexandrina Ferreira Mendes

“…These searches will use combinations of predefined keywords, such as “knee”, “synovial fluid”, “post-traumatic osteoarthritis”, “anterior cruciate ligament”, “meniscus”, “trauma”, “inflammation” and “biomarker”. We will include randomised clinical trials, non-randomised prospective or retrospective clinical studies, case controls, cohort studies and case series, ranging from database inception to 30 June 2024 and published in English. …”
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Relationship between White Blood Count to Mean Platelet Volume Ratio and Clinical Outcomes and Severity of Coronary Artery Disease in Patients Undergoing Primary Percutaneous Coron... by Altekin Refik Emre, Kilinc Ali Yasar, Yanikoglu Atakan, Cicekcibasi Orhan, Kucuk Murathan

“…The white blood cell count to mean platelet volume ratio (WMR) is an indicator of inflammation in patients with atherosclerotic disease. …”
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Body composition, mitochondrial oxygen metabolism and metabolome of patients with obesity before and after bariatric surgery (COMMITMENT): protocol for a monocentric prospective co... by Sina M Coldewey, Charles Neu, Philipp Baumbach, Utz Settmacher, Kornel Skitek, Hermann Kissler, Ricardo Esper Treml

“…Dysfunction of the mitochondrion and systemic low-grade inflammation are among the proposed causes for the metabolic changes. …”
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Ribosomal proteins mediate non-canonical regulation of gut inflammatory signature by crop contaminant deoxynivalenol by Juil Kim, BoGyoung Song, Ki-Hyung Kim, Yuseok Moon

“…Through a combination of transcriptomic analysis and experimental models, we demonstrate that while RPL13A negatively regulates inflammation by enhancing the anti-inflammatory transcription factor ATF3, RPS3 acts as a proinflammatory driver, promoting chemokine production via activation of MAPK pathways, transcriptional upregulation of EGR-1, and stabilization of mRNA through cytosolic translocation of HuR. …”
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Variations in the composition and frequency of celiac disease epitopes among synthetic wheat lines by Rahman Ebrahimzadegan, Ghader Mirzaghaderi

“…Despite the significant importance in breadmaking properties, wheat gluten contains some immunogenic peptides capable of triggering a T cell reaction in celiac disease (CD) patients, leading to inflammation in the small intestine. Among gluten proteins, α-gliadins are the most immunogenic components because they possess the primary T-cell stimulating epitopes (DQ2.5-Glia-α1, DQ2.5-Glia-α2, and DQ2.5-Glia-α3), which are primarily located on the D subgenome. …”
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Protective Effects of Two Safflower Derived Compounds, Kaempferol and Hydroxysafflor Yellow A, on Hyperglycaemic Stress-Induced Podocyte Apoptosis via Modulating of Macrophage M1/M... by Yuanping Li, Dan Zheng, Dayue Shen, Xilan Zhang, Xiaoyun Zhao, Hui Liao

“…The primary initiating mechanism in diabetes nephropathy (DN) is hyperglycemia-induced inflammation in which macrophage and podocyte play important roles. …”
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Regulatory role of S1P and its receptors in sepsis-induced liver injury by Bin Wang, Bin Wang, Xiaoyu Wu, Xiaoyu Wu, Jiangfeng Cheng, Jiangfeng Cheng, Junming Ye, Junming Ye, Hongquan Zhu, Hongquan Zhu, Xiaofeng Liu, Xiaofeng Liu

“…Finally, the relationships between S1P and its receptors with liver inflammation and metabolism and the use of related drugs for the treatment of liver injury were examined. …”
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Correlation between hemoglobin, albumin, lymphocyte, and platelet score and short-term mortality in critically ill patients by Chong Zhang, Wenjin Peng, Meng Ning, Weiru Liang, Bin Su, Tingting Guo, Kun Hu, Wei Su, Yi Chen, Yingwu Liu

“…It serves as a valuable tool for assessing both inflammation and nutritional status in critically ill patients. …”
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Tumor-Infiltrating Lymphocytes and Neutrophils and Their Location in Canine Mammary Neoplasms with a Solid Arrangement: A Prognostic Factor? by Mayra C. Flecher, Marina P. Reys, Débora Balabram, Karen Y. R. Nakagaki, Geovanni D. Cassali

“…In canine mammary neoplasms, greater inflammation is associated with higher histological grade, lymphatic invasion, and metastases. …”
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Microglia modulate the cerebrovascular reactivity through ectonucleotidase CD39 by Zhongxiao Fu, Mallikarjunarao Ganesana, Philip Hwang, Xiao Tan, Melissa Marie Kinkaid, Yu-Yo Sun, Emily Bian, Aden Weybright, Hong-Ru Chen, Katia Sol-Church, Ukpong B. Eyo, Clare Pridans, Francisco J. Quintana, Simon C. Robson, Pankaj Kumar, B. Jill Venton, Anne Schaefer, Chia-Yi Kuan

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Primary ciliary dyskinesia: Meeting the challenges of diagnosis in South Africa by Z Dangor, M Birkhead, C Verwey, D Gray, A Vanker, L Githinji, A Goga, R Masekela, M Zampoli

“… Primary ciliary dyskinesia (PCD) is an inherited ciliopathy that results in impaired mucous clearance and affects primarily the respiratory tract, causing upper airway disease, bronchial inflammation and bronchiectasis. The prevalence of PCD in low- and middle-income settings, including South Africa (SA), is unknown, largely owing to challenges with diagnosis, and identifying children or adults with PCD is challenging in a setting with a high prevalence of other infectious diseases, including lower respiratory tract infections and tuberculosis. …”
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Primary Gallbladder Small Lymphocytic Lymphoma as a Rare Postcholecystectomy Finding by Kyriakos Psarras, Nikolaos Symeonidis, Euthymia Vlachaki, Minas Baltatzis, Georgios Papatolios, Efstathios Pavlidis, Christina Mouratidou, Ioannis Venizelos, Theodoros Pavlidis, Athanasios Sakantamis, Christina Nikolaidou

“…The association of these lesions with chronic inflammation is the most convincing theory for their pathogenesis. …”
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Polymorphism of genes associated with infectious lung diseases in Northern Asian populations and in patients with community-acquired pneumonia by S. V. Mikhailova, L. V. Shcherbakova, N. I. Logvinenko, I. I. Logvinenko, M. I. Voevoda

“…It is responsible for invader recognition, immune-cell recruitment, adaptive-immunity activation, and regulation of inflammation intensity. Previously, two single-nucleotide polymorphisms of innate-immunity genes – rs5743708 (Arg753Gln) of the TLR2 gene and rs8177374 (Ser180Leu) of the TIRAP gene – have been shown to be associated with both pneumonia and tuberculosis in humans, but the data are contradictory among different ethnic groups. …”
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Clinical Characteristics of 31 Patients with Chest Pain Variant Asthma by Mao W, Gao Y, Sun W, Li J, Wang J, Wang Z, Zhang L, Huang K

“…Additionally, 35.5% of the patients meanwhile had allergic rhinitis, and 64.5% of the patients exhibited type 2 inflammation. Among the 31 patients, 22 (71.0%) showed abnormalities on inspiratory computed tomography (CT) scans, including bronchiolar (38.7%), bronchial (25.8%) or pulmonary parenchyma abnormalities (32.3%). …”
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Effect of N-Feruloylserotonin and Methotrexate on Severity of Experimental Arthritis and on Messenger RNA Expression of Key Proinflammatory Markers in Liver by Ľudmila Pašková, Viera Kuncírová, Silvester Poništ, Danica Mihálová, Radomír Nosáľ, Juraj Harmatha, Iveta Hrádková, Tomáš Čavojský, František Bilka, Katarína Šišková, Ingrid Paulíková, Lýdia Bezáková, Katarína Bauerová

“…Administration of either N-f-5HT or MTX caused reduction of inflammation measured as the level of CRP in plasma and the activity of LOX in the liver. mRNA transcription of TNF-α and iNOS in the liver was significantly attenuated in both MTX and N-f-5HT treated groups of arthritic rats. …”
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Work loss in patients with rheumatoid arthritis treated with abatacept, rituximab, tocilizumab or TNF inhibitors: a nationwide direct drug-to-drug comparison by Ulf Lindström, Johan Askling, Katerina Chatzidionysiou, Lotta Ljung, Lars Klareskog, Martin Neovius, Nils Feltelius, Eva Baecklund, Christopher Sjöwall, Helena Forsblad-d’Elia, Carl Turesson, Elisabet Lindqvist, Thomas Frisell, Alf Kastbom, Helena Forsblad-d'Elia, Jonas Söderling, Ann Knight, Gerd-Marie Alenius, Gustaf Magnus Bruze

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Hyaluronic acid-curcumin nanoparticles for preventing the progression of experimental autoimmune uveitis through the Keap1/Nrf2/HO-1 signaling pathway by Weiwei Tang, Xiaomin Huang, Yun-Di Yi, Fan Cao, Manli Deng, Jiawei Fan, Zheng-Xuan Jiang, Li-Ming Tao, Xianwen Wang, Lei Shi

“…Excessive autoimmune inflammation and oxidative stress are major drivers that contribute to the initiation and progression of uveitis. …”
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