A comprehensive analysis of erectile dysfunction prevalence and the impact of prostate conditions on ED among US adults: evidence from NHANES 2001-2004 by Yuhao Zhang, Nan Zang, Yingyue Xiang, Fanlu Lin, Xue Liu, Jing Zhang, Jing Zhang

Get full text

RadBone: bone toxicity following pelvic radiotherapy – a prospective randomised controlled feasibility study evaluating a musculoskeletal health package in women with gynaecologica... by Janelle Yorke, Sarah O’Connell, Sally Taylor, Karen Johnson, Robert G Bristow, Martin Eden, Kate Haslett, John Moore, Rohit Kochhar, Victoria Chatzimavridou Grigoriadou, Lisa H Barraclough, Ivona Baricevic-Jones, Zoe Merchant, Thomas Westwood, Anthony David Whetton, Claire E Higham

Get full text

Direct-Acting Oral Anticoagulants in the Management of Cerebral Venous Sinus Thrombosis—Where Do We Stand? by Nikhil Vojjala, Supriya Peshin, Lakshmi Prasanna Vaishnavi Kattamuri, Rabia Iqbal, Adit Dharia, Jayalekshmi Jayakumar, Rafi Iftekhar, Shagun Singh, Mamtha Balla, Claudia S. Villa Celi, Ramya Ramachandran, Rishab Prabhu, Sumeet K. Yadav, Geetha Krishnamoorthy, Vijendra Singh, Karan Seegobin

Get full text

Potential Risk Factors for In-Hospital Mortality in Patients with Moderate-to-Severe Blunt Multiple Trauma Who Survive Initial Resuscitation by Neslihan Yucel, Tuba Ozturk Demir, Serdar Derya, Hakan Oguzturk, Murat Bicakcioglu, Funda Yetkin

Get full text

Paradoxical dominant negative activity of an immunodeficiency-associated activating PIK3R1 variant by Patsy R Tomlinson, Rachel G Knox, Olga Perisic, Helen Su, Gemma V Brierley, Roger L Williams, Robert K Semple

Get full text

Acceptability of and experiences with menstrual hygiene cups among adolescent girls and young women aged 15–24 in two communities in Lusaka, Zambia: an exploratory study nested in... by Melleh Gondwe, Melvin Simuyaba, Mwelwa Phiri, Chisanga Mwansa, Albertus Schaap, Lucheka Sigande, Kwame Shanaube, Sian Floyd, Sarah Fidler, Helen Ayles, Musonda Simwinga, Bernadette Hensen

Get full text

Detection of CRISPR‒Cas and type I R–M systems in Klebsiella pneumoniae of human and animal origins and their relationship to antibiotic resistance and virulence by Xue Li, Ling Wang, Jinghuan Lin, Yingjuan Gu, Zhihua Liu, Jing Hu

Get full text

CD7‐targeting pro‐apoptotic extracellular vesicles: A novel approach for T‐cell haematological malignancy therapy by Bei Zhang, Jianqiang Chen, Jiming Chen, Yingying Shen, Yinghu Chen, Shibo Wang, Chengyan Zhang, Yuzhou He, Huajun Feng, Jiaoli Wang, Zhijian Cai

Get full text

Mycobacteria Exploit Host GPR84 to Dampen Pro-Inflammatory Responses and Promote Infection in Macrophages by Reziya Wumaier, Ke Zhang, Jing Zhou, Zilu Wen, Zihan Chen, Geyang Luo, Hao Wang, Juliang Qin, Bing Du, Hua Ren, Yanzheng Song, Qian Gao, Bo Yan

Get full text

Constitutive expression of Cas9 and rapamycin-inducible Cre recombinase facilitates conditional genome editing in Plasmodium berghei by Samhita Das, Tanaya Unhale, Carine Marinach, Belsy del Carmen Valeriano Alegria, Camille Roux, Hélène Madry, Badreddine Mohand Oumoussa, Rogerio Amino, Shiroh Iwanaga, Sylvie Briquet, Olivier Silvie

Get full text

Revised recommendations from the CSO-HNS taskforce on performance of tracheotomy during the COVID-19 pandemic – what a difference a year makes by D. D. Sommer, D. Cote, T. McHugh, M. Corsten, M. A. Tewfik, S. Khalili, K. Fung, M. Gupta, N. Sne, P. T. Engels, E. Weitzel, T. F. E. Brown, J. Paul, K. M. Kost, J. A. Anderson, L. Sowerby, D. Mertz, I. J. Witterick

Get full text

Post-craniotomy infections: A point-by-point approach by Giovanni Carone, Marta Bonada, Evelyn Gisell Belotti, Eugenia D'Angeli, Annica Piccardi, Fabio Martino Doniselli, Guido Gubertini, Cecilia Casali, Francesco DiMeco, Massimiliano Del Bene

Get full text

Clonality and the Phenotype–Genotype Correlation of Antimicrobial Resistance in <i>Acinetobacter baumannii</i> Isolates: A Multicenter Study of Clinical Isolates from Romania by Adrian-Gabriel Pană, Pavel Șchiopu, Dan Alexandru Țoc, Vlad Sever Neculicioiu, Anca Butiuc-Keul, Anca Farkas, Matei-Ștefan Dobrescu, Mirela Flonta, Carmen Costache, Izabella Éva Szász, Lia-Monica Junie

Get full text

Mapping the Gaps: A Scoping Review of Virtual Care Solutions for Caregivers of Children with Chronic Illnesses by Nicole Pope, Kathyrn A. Birnie, Melanie Noel, Justine Dol, Danyu Li, Megan Macneil, Darrel Zientek, Victoria Surry, Jennifer N. Stinson

Get full text

Mini-review: Utilization of Vibrio parahaemolyticus virulence coding genes for early detection of acute hepatopancreatic necrosis disease (AHPND) by Munti Yuhana, Usamah Afiff

“… The ability to track the presence of pathogenic Vibrio parahaemolyticus, an AHPND causative agent in shrimp is one of the keys to controlling this infectious disease. A reputable disease diagnosis is appreciated as the ability to track the pathogenic infection when the host abnormality is undetectable due to the low pathogenic cell concentration. …”
Get full text

Evaluating the Efficacy of a Serious Game to Deliver Health Education About Invasive Meningococcal Disease: Clustered Randomized Controlled Equivalence Trial by Lauren Bloomfield, Julie Boston, Martin Masek, Lesley Andrew, Donna Barwood, Amanda Devine

“… BackgroundInvasive meningococcal disease (IMD) is a serious, vaccine-preventable infectious disease that can be life-threatening. Teaching adolescents about the early detection and prevention of IMD can be challenging in a school environment, with educators reporting they lack confidence or expertise to cover this in the classroom environment. …”
Get full text

The clinical utility of tissue polymerase chain reaction, tissue culture and tissue histology in blood culture-negative infective endocarditis in South Africa – insights from the G... by W Endres, P Mkoko, M Ntsekhe

Get full text

Nucleic Acid Aptamers for Human Norovirus GII.4 and GII.17 Virus-Like Particles (VLPs) Exhibit Specific Binding and Inhibit VLPs from Entering Cells by Cheng C, Sun M, Li J, Xue Y, Cai X, Liu J, Wang X, Xu S, Xie Y, Zhang J

“…Chao Cheng,1,&ast; Minjia Sun,1– 3,&ast; Jingjing Li,1,&ast; Yitong Xue,1 Xia Cai,4 Jing Liu,1 Xiaolian Wang,5 Shouhong Xu,2 Youhua Xie,1 Junqi Zhang1 1MOE/NHC/CAMS Key Laboratory of Medical Molecular Virology, Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, People’s Republic of China; 2Key Laboratory for Advanced Materials and Department of Chemistry, East China University of Science and Technology, Shanghai, 200237, People’s Republic of China; 3Zhejiang CONBA Pharmaceutical Co., Ltd, Hangzhou, 310052, People’s Republic of China; 4Shanghai Medical College, Biosafety Level 3 Laboratory, Fudan University, Shanghai, 200032, People’s Republic of China; 5Department of Pathogeny Microbiology and Preventive Medicine, School of Medicine, Hexi University, Zhangye, 734000, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Junqi Zhang, Email junqizhang@fudan.edu.cn; Youhua Xie, Email yhxie@fudan.edu.cnPurpose: Human noroviruses (HuNoVs) are the main cause of non-bacterial acute gastroenteritis. …”
Get full text

Comparison of Clinical Characteristics and Mortality Outcome in Critical COVID-19 Patients Infected with Alpha and Omicron Variants by Cheng HI, Chang KW, Wu BC, Teo MY, Hung WS, Wu HM, Huang ACC, Lin CW, Lin TY, Lin HC, Chiu CH, Lin SM

“…Hsin-I Cheng,1 Ko-Wei Chang,1 Bing-Chen Wu,1 Mei-Yuan Teo,1 Wei-Syun Hung,1 Hao-Ming Wu,1 Allen Chung-Cheng Huang,1 Chang-Wei Lin,2 Ting-Yu Lin,1 Horng-Chyuan Lin,1 Cheng-Hsun Chiu,3,4 Shu-Min Lin1,5– 7 1Department of Thoracic Medicine, Chang Gung Memorial Hospital, Linkuo, Taiwan; 2Department of Thoracic Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan; 3Department of Pediatrics, Chang Gung Children’s Hospital, Chang Gung University College of Medicine, Taoyuan City, Taiwan; 4Molecular Infectious Disease Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan; 5Department of Respiratory Therapy, Chang Gung Memorial Hospital, Linkuo, Taiwan; 6School of Medicine, National Tsing Hua University, Hsin-Chu, Taiwan; 7School of Medicine, Chang Gung University, Taoyuan, TaiwanCorrespondence: Shu-Min Lin, Department of Thoracic Medicine, Chang Gung Memorial Hospital, 199 Tun-Hwa N. …”
Get full text

Viral Mimetic Bacterial Outer Membrane Vesicles for Targeting Angiotensin-Converting Enzyme 2 by Ahn G, Yoon HW, Jeong JH, Kim YH, Shin WR, Song MS, Ahn JY

“…Experiments in mice, Ag43β 700_RBD OMVs was successfully proven to be safe and effective; they produced a detectable level of nAbs with 39– 58% neutralisation and reduced viral titres in the lungs and brain without weight loss.Conclusion: The developed viral mimetic Ag43β 700_RBD OMVs may therefore be applied as a nanovesicle-theranostic platform for further emerging infectious disease-related diagnosis, vaccination, and treatment. …”
Get full text