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Antibody and serum bactericidal response to Burkholderia pseudomallei in acute localized and septicemic melioidosis cases with diabetes mellitus
Published 2025-01-01“…Conclusion: The results indicate that high anti- B. pseudomallei IgM/IgG and serum bactericidal antibodies are induced in diabetic patients with septicemia and suppurative infections. This immune response in diabetics might be important to contain the infection and help in recovery. …”
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122
Immunologic and inflammatory consequences of SARS-CoV-2 infection and its implications in renal disease
Published 2025-02-01“…Lymphopenia, more apparent among natural killer (NK) cells, CD8+ T-cells, and B-cells, can contribute to disease severity and may reflect direct cytopathic effects of SARS-CoV-2 or end-organ sequestration. Direct infection and immune activation of endothelial cells by SARS-CoV-2 may be a critical mechanism through which end-organ systems are impacted. …”
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123
Early COVID-19 and protection from Omicron in a highly vaccinated population in Ontario, Canada: a matched prospective cohort study
Published 2025-02-01“…Abstract Objectives Predictions regarding the on-going burden of SARS-CoV-2, and vaccine recommendations, require an understanding of infection-associated immune protection. We assessed whether early COVID-19 provided protection against Omicron infection. …”
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124
Bifurcation analysis of multistability and hysteresis in a model of HIV infection
Published 2023-12-01“…HIV-1 control efforts with reliance on immunotherapy remain at a conceptual stage due to the complexity of a set of processes that regulate the dynamics of infection and immune response. For this reason, it is extremely important to use methods of mathematical modeling of HIV-1 infection dynamics for theoretical analysis of possibilities of reducing the viral load by affecting the immune system without the usage of antiviral therapy. …”
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