Delineation of the Genetic Architecture and Clinical Polymorphism of 3q29 Duplication Syndrome: A Review of the Literature and a Report of Two Novel Patients With Single‐Gene BDH1... by A. A. Kashevarova, M. E. Lopatkina, O. Yu. Vasilyeva, D. A. Fedotov, A. D. Lobanov, E. A. Fonova, I. Z. Zhalsanova, A. A. Zarubin, O. A. Salyukova, E. O. Belyaeva, V. V. Petrova, E. G. Ravzhaeva, A. A. Agafonova, A. D. Cheremnykh, N. B. Torkhova, S. L. Vovk, I. N. Lebedev

“…Schizophrenia, generalized anxiety disorder, and recurrent ear infections were unique phenotypes of patients carrying deletions. …”
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Blood transcriptome resources of chinstrap () and gentoo () penguins from the South Shetland Islands, Antarctica by Bo-Mi Kim, Jihye Jeong, Euna Jo, Do-Hwan Ahn, Jeong-Hoon Kim, Jae-Sung Rhee, Hyun Park

“…In the blood transcriptomes, KEGG analyses detected many essential genes involved in the major innate immunity pathways, which are key metabolic pathways for maintaining homeostasis against exogenous infections or toxins. Blood transcriptome studies such as this may be useful for checking the immune and health status of penguins without sacrifice.…”
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Biochar filtration of drug-resistant bacteria and active pharmaceutical ingredients to combat antimicrobial resistance by Paul-Enguerrand Fady, Alexandra K. Richardson, Leon P. Barron, A. James Mason, Roberto Volpe, Meredith R. Barr

“…Abstract Antimicrobial resistance (AMR) is a major cause of death worldwide, with 1.27 M direct deaths from bacterial drug-resistant infections as of 2019. Dissemination of multidrug-resistant (MDR) bacteria in the environment, in conjunction with pharmapollution by active pharmaceutical ingredients (APIs), create and foster an environmental reservoir of AMR. …”
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Prospects of employing modern European cultivars of spring bread wheat in the breeding for powdery mildew resistance in the Northwestern region of Russia by T. V. Lebedeva, E. V. Zuev, A. N. Brykova

“…Marchal is a widespread foliar disease of wheat in regions with cool and wet climate. It infects the foliage, stem and spike of the wheat host and causes yield reduction. …”
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Generation of Mature Nα-Terminal Acetylated Thymosin α1 by Cleavage of Recombinant Prothymosin α by Bo Liu, Xin Gong, Shaohong Chang, Peng Sun, Jun Wu

“…Nα-terminal acetylated thymosin α1 (Tα1), a 28-amino-acid peptide, is an immune modifier that has been used in the clinic to treat hepatitis B and C virus (HBV/HCV) infections. We previously documented Nα-terminal acetylation of recombinant prothymosin α (ProTα) in E. coli. …”
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Comparative Biotypic and Phylogenetic Profiles of Escherichia coli Isolated from Resident Stool and Lagoon in Fresco (Côte d’Ivoire) by Nadége Kouadio-Ngbesso, Koua Atobla, Paul Yao Attien, Mireille Kouame-Sina, René Ahua Koffi, Antoinette Ama Adingra, Adjehi Dadié

“…A close relationship was found between water and human strains, and the presence of commensal and extraintestinal pathogenic E. coli in all samples could represent a potential reservoir of extraintestinal infections for resident populations.…”
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Therapeutic applications of novel drug delivery systems of liquorice: An updated review on recent advancements by Sanshita, Taneja Ayushi, Sangnim Tanikan, Huanbutta Kampanart, Sindhu Rakesh K., Singh Inderbir

“…It exhibits broad spectrum biological activities such as anti-inflammatory, immunomodulatory, anti-oxidant, anti-cancer, anti-diabetic, anti-microbial properties and is used in the treatment of different diseases such as cancer, inflammation, viral infections, cardiovascular and respiratory disorders. …”
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High-Throughput 16 S rRNA Gene Sequencing Reveals Bacterial Diversity of Infant Formula Production Line Samples in Spring and Summer by Xian Li, Yongbo Li, Yalun Zhang, Rui Zhang, Hui Wang, Tao Zhang, Taotao Yan, Zilun Zhang, Guohua Shi, Wei Zhou

“…The trend of low breastfeeding rates increases the demand for infant milk formula (IMF) worldwide, but the use of IMF may be one of the causes of bacterial infections in infants. Complete sterility in the whole production line of IMF cannot be guaranteed; therefore, it is necessary to closely monitor the microbial content in the process. …”
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Discovery of Quinazolone Pyridiniums as Potential Broad-Spectrum Antibacterial Agents by Jie Dai, Qianyue Li, Ziyi Li, Zhonglin Zang, Yan Luo, Chenghe Zhou

“…The overprescription of antibiotics in medicine and agriculture has accelerated the development and spread of antibiotic resistance in bacteria, which severely limits the arsenal available to clinicians for treating bacterial infections. This work discovered a new class of heteroarylcyanovinyl quinazolones and quinazolone pyridiniums to surmount the increasingly severe bacterial resistance. …”
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Dynamics of blackleg epizootic process in the Republic of Kazakhstan by A. Abutalip, B. D. Aitzhanov, A. K. Mussayeva, V. Yu. Sushchikh, N. N. Yegorova, Ye. K. Ospanov, M. A. Berdikulov, K. A. Kalkabayev, N. Matikhan

“…Within the mentioned period, the average number of blackleg-infected animals per one outbreak ranged between1 and 3 animals, which proves that blackleg is anon-contagious disease. …”
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Impacts of COVID-19 on Pregnancy Outcomes: A Retrospective Study by Donna Mendez, Krishna Paul, Jerome L. Yaklic, Dietrich Jehle

“…Conclusions: There is an increased risk of poor outcomes for pregnant women infected with COVID-19; however, fetal outcomes are generally favorable. …”
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Drastic Improvements in Air Quality in Ecuador during the COVID-19 Outbreak by Rasa Zalakeviciute, Renne Vasquez, Daniel Bayas, Adrian Buenano, Danilo Mejia, Rafael Zegarra, Valeria Diaz, Brian Lamb

“…This country implemented a particularly strict set of quarantine measures at the very dawn of the exponential growth of infections on March 17, 2020. As a result, significant reductions in the concentrations of NO2 (–68%), SO2 (–48%), CO (–38%) and PM2.5 (–29%) were measured in the capital city of Quito during the first month of quarantine. …”
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Analysis of the efficacy of MALDI-TOF MS technology in identifying microorganisms in cancer patients and oncology hospital environment by Grażyna Czeszewska-Rosiak, Iwona Adamczyk, Agnieszka Ludwiczak, Piotr Fijałkowski, Paweł Fijałkowski, Magdalena Twarużek, Michał Złoch, Dorota Gabryś, Wioletta Miśta, Andrzej Tretyn, Paweł Piotr Pomastowski

“…Rapid diagnostics of microbes in hospitals are crucial for promptly identifying infections, enabling timely and appropriate treatment. …”
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Investigating resistance to 5-Azacytidine and Venetoclax in PDX models of MDS/AML by Petra Bašová, Lubomír Minařík, Lubomír Minařík, Silvia Carina Magalhaes-Novais, Jana Balounová, Zuzana Zemanová, Tatiana Aghová, Martin Špaček, Anna Jonášová, Kristýna Gloc Pimková, Jan Procházka, Radislav Sedláček, Tomáš Stopka, Tomáš Stopka

“…PDX were created in NSGS mice via intraosseal injection of luciferase-encoding Lentivirus-infected MDS/AML primary cells from patient bone marrow. …”
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Brighter children? The association between seasonality of birth and child IQ in a population-based birth cohort by Vincent W V Jaddoe, Régine P M Steegers-Theunissen, Henning Tiemeier, Albert Hofman, Frank C Verhulst, Nina H Grootendorst-van Mil

“…We explored how adjusting for socioeconomic status and maternal IQ, childbirth outcomes, pregnancy vitamin D status, nutritional intake, exposure to infections, and child age relative to peers in class changed the relation between season of birth and child IQ.Results We found that spring birth was associated with lower non-verbal IQ (estimate: more than 1 point; β−1.24 (95% CI −2.31 to −0.17), p=0.02; seasonal trend β−0.40 (95% CI −0.74 to −0.07), p=0.02) than birth in summer. …”
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Mendelian Susceptibility to Mycobacterial Diseases (MSMD) in a 13-Year-Old Ethiopian Girl with Autosomal Dominant Interferon Gamma Receptor 1(IFN-γ R1) Defect: A Clinical Diagnosti... by Netsanet Azene Gebeyehu, Solomie Jebessa Deribessa, Freeman Alexandra, Messay Tesfaye Demissie, W Mihretu Gebre, Aklilu Melaku Gebremariam, Dagmawit Mitiku Engliz, Tizita Yosef Kidane, Lidya Million Bekele, Abate Yeshidinber Weldetsadik

“…The most striking diagnosis was repeated mycobacterial infections. She had tuberculosis affecting lymph nodes, skin and soft tissue, bone and joints, the lungs, and epidural and paraspinal regions. …”
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Mycobacterium tuberculosis Protein Rv3841 Activates Dendritic Cells and Contributes to a T Helper 1 Immune Response by Seunga Choi, Han-Gyu Choi, Ki-Won Shin, Yong Woo Back, Hye-Soo Park, Jae Hwi Lee, Hwa-Jung Kim

“…Moreover, Rv3841 specifically caused the expansion of CD4+CD44highCD62Llow T-cells from Mtb-infected mice; besides, the T-cells activated by Rv3841-matured DCs inhibited intracellular mycobacterial growth. …”
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Clonality and the Phenotype–Genotype Correlation of Antimicrobial Resistance in <i>Acinetobacter baumannii</i> Isolates: A Multicenter Study of Clinical Isolates from Romania by Adrian-Gabriel Pană, Pavel Șchiopu, Dan Alexandru Țoc, Vlad Sever Neculicioiu, Anca Butiuc-Keul, Anca Farkas, Matei-Ștefan Dobrescu, Mirela Flonta, Carmen Costache, Izabella Éva Szász, Lia-Monica Junie

“…Amongst the main species driving this phenomenon is <i>A. baumannii</i>, a member of the ESKAPE group of medical assistance-associated infections causing species famous for its extensively drug-resistant phenotypes. …”
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Case Report on Renal Failure Reversal in Lambda Chain Multiple Myeloma with Bortezomib and Dexamethasone by Bhanu K. Patibandla, Akshita Narra, Ahmad A. Alwassia, Anthony Bartley, Gurprataap S. Sandhu, James Rooney, Robert M. Black

“…Light chain myeloma, serum creatinine (SCr) > 4 mg/dL, extensive proteinuria, early infections, and certain renal biopsy findings are associated with lower rates of RF reversal. …”
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Detection of Francisellaceae and the differentiation of main European F. tularensis ssp. holarctica strains (Clades) by new designed qPCR assays by Kristin Köppen, Kerstin Rydzewski, Julia Zajac, Marwah Al-Senwi, Sema Evcimen, Darius Schulze, Daniela Jacob, Klaus Heuner

“…Tularemia in humans is mainly caused by F. tularensis subspecies tularensis and holarctica, but Francisella species like F. novicida, F. philomiragia, F. hispaniensis and others are known to cause tularemia-like infections in immunocompromised humans. In addition to these Francisella species, further genera of the family Francisellaceae have been described, such as Allofrancisella, Parafrancisella and Pseudofrancisella, but less is known about the distribution and putative virulence of these genera. …”
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