Comprehensive epidemiological evaluation of ruminant brucellosis and associated risk factors in some Egyptian Governorates by Nesreen Allam Tantawy Allam, Mahinour Ezzeldin Abdelsalam, Hend I. Elsharkawy, Mai Mohamed Kandil, Amany Mohamed Mohamed Mohamed, Fatma Ali, Mohamed A. Gebely, Safaa Y. Nour, Doaa Sedky, Mona Ebrahim Hussien Abd El-Gawad, Hoda M. Zaki, Nazek Al-Gallas, Amal M. Aboelmaaty, Mona Mohamed Sobhy, Nagwa Sayed Ata, Marwa Salah Abdel-Hamid, Ghada A. Badawy

“…The difficulty in accurately diagnosing all infected animals, particularly carriers, is a major limitation of eradication and control programs. …”
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Understanding Nigeria’s antibiotic resistance crisis among neonates and its future implications by Victor Oluwatomiwa Ajekiigbe, Ikponmwosa Jude Ogieuhi, Temiloluwa Adebayo Odeniyi, Praise Oluwatobi Ogunleke, Josiah Temitope Olatunde, Adedoyin Veronica Babalola, Akintunde Abisoye Omoleke, Tolulope Felix Omitade, Damilare Emmanuel Olakanmi, Adewunmi Akingbola, Chidera Stanley Anthony

“…Studies show a significant rise in multi-drug-resistant infections, with almost half of Escherichia coli and 86% of Staphylococcus aureus strains among newborns resistant to conventionally used antibiotics like penicillin. …”
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From Isolation to Application: Utilising Phage‐Antibiotic Synergy in Murine Bacteremia Model to Combat Multidrug‐Resistant Enterococcus faecalis by Fatma Al‐zahraa A. Yehia, Galal Yahya, Eslam M. Elsayed, Javier Serrania, Anke Becker, Salwa E. Gomaa

“…ABSTRACT Enterococcus species, natural inhabitants of the human gut, have become major causes of life‐threatening bloodstream infections (BSIs) and the third most frequent cause of hospital‐acquired bacteremia. …”
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The Prevalence of Enteric Viruses in Bivalve Molluscs in a Farming Area in Liguria, Northwest Italy by Chiara Masotti, Laura Serracca, Erica Costa, Barbara Betti, Aitor Garcia-Vozmediano, Elisabetta Suffredini, Roberta Battistini

“…Although norovirus (NoV) and the hepatitis A virus (HAV) are considered the most common causes of foodborne infections, in recent years, other viruses with a zoonotic potential have been identified in shellfish, such as the hepatitis E virus (HEV), astrovirus (AsV), and aichi virus (AiV). …”
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Prevalence, Molecular Epidemiology, and Clinical Characteristics of Human Bocavirus Among Patients with Acute Gastroenteritis in Northern Brazil During 2017–2022 by Yasmim Gabrielly Souza Sousa, Carolina Alcântara Maneschy, Carolina Costa Monteiro, João Victor Souza Rodrigues, Patrícia Santos Lobo, Dielle Monteiro Teixeira, Jones Anderson Monteiro Siqueira, Kenny Costa Pinheiro, Hugo Reis Resque, Luciana Damascena Silva, Sylvia Fátima dos Santos Guerra, Luana Silva Soares

“…Genotypes HBoV-1, HBoV-2, HBoV-3, and HBoV-4 were found in 42.5% (17/40), 22.5% (9/40), 32.5% (13/40), and 2.5% (1/40) of the specimens, respectively. Co-infections with HBoV and other enteric viruses occurred in 48.3% (31/64) of cases, with RVA being the most frequent (31.2%, 20/64). …”
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Water Birth – Benefits, Risks, and Controversies by Julia Górny, Alicja Kapciak, Katarzyna Naja, Jakub Zwardoń, Artur Hawajski, Natalia Jankowska, Oliwia Kamieniecka, Adrianna Świerzyńska, Weronika Mazur, Natalia Pawelec

“…Water birth, however, carries potential risks, such as neonatal respiratory complications and infections, although studies generally report no significant differences in neonatal outcomes compared to land birth. …”
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Eugenol targeting CrtM inhibits the biosynthesis of staphyloxanthin in Staphylococcus aureus by Jiang Chang, Bo Chen, Zeqian Du, Bowen Zhao, Jiahui Li, Ziyi Li, Kannappan Arunachalam, Ting Shi, Dongqing Wei, Chunlei Shi

“…Taken together, we first determined that eugenol was a prominent compound for staphyloxanthin inhibitor to combat S. aureus especially MRSA infections.…”
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Population Structure Based on Microsatellite Length Polymorphism, Antifungal Susceptibility Profile, and Enzymatic Activity of <i>Candida auris</i> Clinical Isolates in Russia by Ellina Oganesyan, Victoria Klimenteva, Irina Vybornova, Valentina Venchakova, Ekaterina Parshikova, Sergey Kovyrshin, Olga Orlova, Alexander Kruglov, Svetlana Gordeeva, Natalya Vasilyeva, Anastasiya Taraskina

“…<i>Candida auris</i> is an emerging multidrug-resistant fungal pathogen causing nosocomial transmission and invasive infections with high mortality. This study aimed to investigate the genetic relationships, enzymatic activities, and drug-resistance profiles of <i>C. auris</i> isolates to evaluate the population and epidemiological diversity of candidiasis in Russia. …”
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A mechanistic overview on green assisted formulation of nanocomposites and their multifunctional role in biomedical applications by Mahnoor, Khafsa Malik, Abeer Kazmi, Tahira Sultana, Naveed Iqbal Raja, Yamin Bibi, Mazhar Abbas, Irfan Anjum Badruddin, M. Mahmood Ali, Muhammad Nasir Bashir

“…Incorporating phytosynthesized nanocomposites in therapeutic interventions not only enhances healing processes but also augments the host's immune defenses against infections. This review highlights the phytosynthesis of nanocomposites and their various biomedical applications, including antibacterial, antidiabetic, antiviral, antioxidant, antifungal, anti-cancer, and other applications, as well as their toxicity. …”
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<i>In Vitro</i> and <i>In Vivo</i> Evaluation of the Antischistosomal Activity of Polygodial and 9-Deoxymuzigadial Isolated from <i>Drimys brasiliensis</i> Branches by Eric Umehara, Rayssa A. Cajas, Gabriel B. Conceição, Guilherme M. Antar, Adriano D. Andricopulo, Josué de Moraes, João Henrique G. Lago

“…Finally, in vivo studies with <i>S. mansoni</i>-infected mice treated with compound <b>1</b> demonstrated a 44.0% reduction in worm burden, accompanied by decreases in egg production of 71.8% in feces and 69.5% in intestines. …”
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Correlation between Intraoperative Fluid Administration and Outcomes of Pancreatoduodenectomy by Xuefeng Cao, Xixiu Wang, Baolei Zhao, Lingqun Kong, Lei Zhou, Wentao Zhu, Xutao Lin, Qiangpu Chen, Xingyuan Zhang

“…The in-hospital mortality rate was 7.28% with the most common cause being grade C POPF and secondary intra-abdominal infections. The patients in the liberal group had significantly higher incidences of POPF (25%) and respiratory complications (21.43%). …”
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Prognostic Value of Concomitant Bronchiectasis in Newly Diagnosed Diffuse Panbronchiolitis Patients on a Maintenance Therapy with Macrolides by Benyong Xu, Yanhua Mao, Xiaoyu Wan, Jianhui Chen, Meiping Ye, Mengling Zhan, Liyun Xu, Lan Zhao, Bing Li, Zhemin Zhang, Yang Liu, Haiqing Chu

“…The coexistence of bronchiectasis predicted a poor outcome of maintenance macrolide therapy and an increased exacerbation risk in DPB subjects, possibly through its impacts on nutritional status, pulmonary function, and P. aeruginosa infections.…”
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CRISPR-Cas9-mediated editing of ZmPL1 gene improves tolerance to drought stress in maize by Chunlai Wang, Yangyang Zhou, Yimeng Wang, Peng Jiao, Siyan Liu, Shuyang Guan, Yiyong Ma

“…Next, ZmPL1 transgenic plants were obtained by infecting maize callus using Agrobacterium-mediated method. …”
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Microbiological Quality and Risk Assessment for Aflatoxins in Groundnuts and Roasted Cashew Nuts Meant for Human Consumption by Modupeade Christianah Adetunji, Ogechi Precious Alika, Ngozi Precious Awa, Olusegun Oladimeji Atanda, Mulunda Mwanza

“…Nuts are one of the commonly consumed snacks but poor handling and storage practices can make them prone to foodborne infections. The study aimed at assessing the microbiological quality and risk assessment for aflatoxins in groundnuts and cashew nuts consumed in selected locations in Nigeria. …”
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Stability and computational analysis of Influenza-A epidemic model through double time delay by Ateq Alsaadi, Ali Raza, Muhammed Bilal Riaz, Umar Shafique

“…The four distinct sub-populations are considered susceptible, exposed, infected, and recovered. For the rigorous analysis, the fundamental properties of the model like positivity, boundedness, existence, and uniqueness, were studied. …”
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The Global Challenge of <i>Campylobacter</i>: Antimicrobial Resistance and Emerging Intervention Strategies by Zubeiru Bukari, Toyin Emmanuel, Jude Woodward, Richard Ferguson, Martha Ezughara, Nikhil Darga, Bruno Silvester Lopes

“…Resistance to fluoroquinolones, macrolides, and tetracyclines complicates treatment and increases the risk of severe infections. Drug-resistant <i>Campylobacter</i> is transmitted to humans via contaminated food, water, and direct contact with animals, highlighting its zoonotic potential. …”
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Pharmacophore-based approach for the identification of prospective UDP-2,3-diacylglucosamine hydrolase (LpxH) inhibitor from natural product database against Salmonella Typhi by Divyapriya Karthikeyan, Sanjit Kumar, NS Jayaprakash

“…The study concluded that compounds 1615 and 1553 hold significant potential as lead molecules for developing new treatments against drug-resistant S. Typhi infections. This study illustrates how computational techniques, such as MD simulations and pharmacophore modeling, can speed up drug discovery, especially in the fight against antibiotic resistance.…”
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Detection and Whole-Genome Characteristics of <i>Bordetella trematum</i> Isolated from Captive Snakes by Magdalena Zając, Inga Bona, Magdalena Skarżyńska, Renata Kwit, Anna Lalak, Ewelina Skrzypiec, Emilia Mikos-Wojewoda, Paulina Pasim, Dominika Wojdat, Weronika Koza, Dariusz Wasyl

“…<i>Bordetella trematum</i> is a rare member of the genus <i>Bordetella</i>, primarily associated with human wound infections rather than respiratory diseases. The bacterium has been isolated from various clinical specimens, including ear inflammatory discharge, diabetic ulcers, and chronic wounds. …”
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Machine learning and genetic algorithm-guided directed evolution for the development of antimicrobial peptides by Heqian Zhang, Yihan Wang, Yanran Zhu, Pengtao Huang, Qiandi Gao, Xiaojie Li, Zhaoying Chen, Yu Liu, Jiakun Jiang, Yuan Gao, Jiaquan Huang, Zhiwei Qin

“…Introduction: Antimicrobial peptides (AMPs) are valuable alternatives to traditional antibiotics, possess a variety of potent biological activities and exhibit immunomodulatory effects that alleviate difficult-to-treat infections. Clarifying the structure-activity relationships of AMPs can direct the synthesis of desirable peptide therapeutics. …”
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Penetration of linezolid and tedizolid in cerebrospinal fluid of mouse and impact of blood–brain barrier disruption by Marin Lahouati, Mélanie Oudart, Philippe Alzieu, Candice Chapouly, Antoine Petitcollin, Fabien Xuereb

“…Abstract Penetration of antimicrobial treatments into the cerebrospinal fluid is essential to successfully treat infections of the central nervous system. This penetration is hindered by different barriers, including the blood–brain barrier, which is the most impermeable. …”
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