Helminth Products Potently Modulate Experimental Autoimmune Encephalomyelitis by Downregulating Neuroinflammation and Promoting a Suppressive Microenvironment by Alberto N. Peón, Yadira Ledesma-Soto, Jonadab E. Olguín, Marcel Bautista-Donis, Edda Sciutto, Luis I. Terrazas

“…A negative correlation between the geographical distribution of autoimmune diseases and helminth infections has been largely associated in the last few years with a possible role for such type of parasites in the regulation of inflammatory diseases, suggesting new pathways for drug development. …”
Get full text

Exploring green synthesis of parietin-mediated silver nanoparticles using γ-ray induced Xanthoria parietina foliose extracts for antibacterial potential by Sikander Ali, Alisha Moazzam, Saima Shahzad Mirza, Majid Mahmood, Sibtain Ahmed, Muhammad Usman Ahmad, Gildardo Rivera, Akhtar Rasool Asif, Muhammad Arshad, Mirza Imran Shahzad, Kaynat William, Sundas Sharif

“…The current results exhibited that Xa-AgNPs are potent bactericidal agents and should be considered a promising candidate to combat bacterial infections.…”
Get full text

High Level Aminoglycoside Resistance and Distribution of Aminoglycoside Resistant Genes among Clinical Isolates of Enterococcus Species in Chennai, India by Elango Padmasini, R. Padmaraj, S. Srivani Ramesh

“…Aminoglycosides along with cell wall inhibitors are given clinically for treating enterococcal infections. 178 enterococcal isolates were analyzed in this study. …”
Get full text

Possible Role of Large Fluid Intake in Delaying Formation of Encrustations and, thereby, Prolonging Working Life of Memokath Stent for Nearly 14 Years in a Spinal Cord Injury Patie... by Subramanian Vaidyanathan, Bakul M. Soni, Peter L. Hughes, Gupreet Singh

“…Large fluid intake resulted in high urine output and, consequently, deceased the risk of urine infections and delayed formation of encrustations around the stent. …”
Get full text

Expanding the BP1-BP2 15q11.2 Microdeletion Phenotype: Tracheoesophageal Fistula and Congenital Cataracts by D. Wong, S. M. Johnson, D. Young, L. Iwamoto, S. Sood, T. P. Slavin

“…The region is approximately 500 kb and microdeletions within the BP1-BP2 region have been reported in patients with developmental delay, behavioral abnormalities, and motor apraxia as well as dysmorphic features including hypertelorism, cleft or narrow palate, ear abnormalities, and recurrent upper airway infections. We report two patients with unique, never-before-reported 15q11.2 BP1-2 microdeletion syndrome findings, one with proximal esophageal atresia and distal tracheoesophageal fistula (type C) and one with congenital cataracts. …”
Get full text

Extended Spectrum Beta-Lactamase Carriage State among Elderly Nursing Home Residents in Beirut by M. A. Jallad, R. Naoufal, J. Irani, E. Azar

“…ESBL-producing Enterobacteriaceae can cause severe infections, but they are also isolated from the stool of asymptomatic subjects. …”
Get full text

Nucleic Acid-based Identification of Major Honeybee (Apis mellifera L.) Viruses in the Jammu Region of India by Ram Narayan Sharma Ram, Devinder Sharma, Biswajit Brahma, Pradeep Kumar Kumawat, Sharad Kumar Meena

“…Using the RT-PCR technology, research was done to confirm that A. mellifera is infected by the Israeli acute paralysis virus (IAPV), the Thai sacbrood virus (TSBV), the Kashmir bee virus (KBV), and sacbrood virus (SBV). …”
Get full text

Secretory Leukocyte Protease Inhibitor Is an Inducible Antimicrobial Peptide Expressed in Staphylococcus aureus Endophthalmitis by Victor E. Reviglio, Ruben H. Sambuelli, Alejandra Olmedo, Micaela Falco, Jose Echenique, Terrence P. O'Brien, Irene C. Kuo

“…Western blots confirmed increased SLPI expression in all infected eyes. By immunohistochemical assays, SLPI was absent in the BSS and control eyes. …”
Get full text

Locked-in Syndrome: Insights into Etiology, Diagnosis, Management, and Quality of Life by Urszula Zelik, Wojciech Florczak, Joanna Śnieżna, Jakub Dziewic, Karol Dzwonnik, Wiktoria Domino, Gabriela Trestka, Maria Przygoda, Jagienka Włodyka, Kamila Stępień, Sabina Adamczyk

“…This review consolidates current knowledge on the etiology, diagnosis, management, and quality of life in LIS, emphasizing its complexity and the need for a multidisciplinary approach.The condition’s etiological spectrum includes vascular events, trauma, infections, and demyelinating disorders, necessitating a comprehensive diagnostic approach integrating advanced neuroimaging and electrophysiological tools. …”
Get full text

Pradofloxacin Minimum Inhibitory Concentration Profiling of <i>Streptococcus suis</i> Isolates: Insights into Antimicrobial Susceptibility in Swine by Jessica Risser, Ronald Tessman, Don Bade, Orhan Sahin, Maria J. Clavijo, Saumya Dhup, Patrick Hoffmann

“…These findings suggest that pradofloxacin has broad-spectrum activity against Gram-positive and Gram-negative bacteria and may serve as a reliable therapeutic option for managing <i>S. suis</i> and other swine respiratory infections. This study highlights pradofloxacin as an alternative antimicrobial therapy for swine respiratory diseases, offering a potential solution amidst rising concerns over antibiotic resistance.…”
Get full text

An Evaluation of Quality of Life after Ventral Hernia Repair Using the EuraHS-QoL Score: a Cross-Sectional Survey by Harshit Kumar Prabhakar, Vipin V Nair, Pranay Pratap, Sarath Kumar, Brig Alok Bhalla

“…Three patients suffered surgery site infections and one had skin dehiscence. All patients showed overall improvement of QoL at the end of 90 days. …”
Get full text

Immunological Impacts of Diabetes on the Susceptibility of Mycobacterium tuberculosis by Birhanu Ayelign, Markos Negash, Meaza Genetu, Tadelo Wondmagegn, Tewodros Shibabaw

“…The interaction between diabetes and major world infections like TB is a major public health concern because of rapidly rising levels of diabetes. …”
Get full text

A New Combination Formula for Treatment of Fungal Keratitis: An Experimental Study by Hala Mohamed El-Mofty, Mohamad Amr Salah Eddin Abdelhakim, Mohamed Farid El-Miligi, Mohamed A. El-Nabarawi, Islam Ahmed Hamed Khalil

“…Gels containing high polymer concentration showed both high viscosity and mucoadhesion properties with slower drug release. The infected eyes treated with slow release formula containing both drugs showed better curing of the cornea and pathologically less inflammation than eyes treated with fast release formula. …”
Get full text

Effectiveness of rehabilitation interventions in patients with colorectal cancer: an overview of systematic reviews by Mengzhe Yang, Bhasker Amatya, Sana Malik, Krystal Song, Stefanie Marcella, Catherine Voutier, Fary Khan

“…The findings suggest: moderate-quality evidence for exercise interventions for improving physical fitness and quality of life; high-quality evidence for nutritional interventions in reducing postoperative infections; high-quality evidence for multimodal prehabilitation for improved preoperative functional capacity; moderate-quality evidence for nutritional interventions for improving humoral immunity, reducing inflammation, and length of stay; moderate-quality evidence for acupuncture in improving gastrointestinal functional recovery; psychosocial interventions in improving short-term quality of life and mental health, and lifestyle interventions for improved quality of life. …”
Get full text

Community-Acquired Rotavirus Gastroenteritis Compared with Adenovirus and Norovirus Gastroenteritis in Italian Children: A Pedianet Study by D. Donà, E. Mozzo, A. Scamarcia, G. Picelli, M. Villa, L. Cantarutti, C. Giaquinto

“…Risk of hospitalisation, access to emergency room (ER), and workdays lost from parents were not significantly different in RVGEs compared to the other viral infections. Conclusions. Features of RVGE in terms of hospitalisation length and indirect cost are lower than those reported in previous studies. …”
Get full text

Lactoferrin exhibits PEDV antiviral activity by interfering with spike-heparan sulfate proteoglycans binding and activating mucosal immune response by Peng Liu, Jinjiao Zuo, Hui Lu, Bin Zhang, Caihong Wu

“…Abstract Neonatal piglets infected with Porcine Epidemic Diarrhea Virus (PEDV) experience a mortality rate of up to 90%, resulting in significant economic losses to the swine industry in China. …”
Get full text

The Optimal Intervention Time of Bone Marrow Mesenchymal Stem Cells in Ameliorating Cardiac Fibrosis Induced by Viral Myocarditis: A Randomized Controlled Trial in Mice by Tingting Wu, Yuan Xie, Jing Huang, Ping Li, Xuliang Wang, Yaoyao Yan, Tianhe Xia, Lei Li, Feng Zhu, Hao Li, Rongzhou Wu

“…On the 1st day, 3rd day, 7th day, and 14th day after BALB/c mice were infected by CVB3, we intravenously injected equivalent BMSCs into the treatment groups. …”
Get full text

Perceptions and Practices towards Anthrax in Selected Agricultural Communities in Arua District, Uganda by Joseph M. Kungu, Peninah Nsamba, Alfred Wejuli, John D. Kabasa, William Bazeyo

“…Poor practices associated with anthrax outbreaks included poor disposal of carcasses and ruminal wastes, occupational hazards (butchers, slaughter men, and herdsmen), consumption of meat from infected animals, communal herding, and cultural norms encouraging consumption of dead animals. …”
Get full text

Eosinophil as a Protective Cell in S. aureus Ventilator-Associated Pneumonia by Ana Rodriguez-Fernandez, David Andaluz-Ojeda, Raquel Almansa, Mar Justel, Jose Maria Eiros, Raul Ortiz de Lejarazu

“…Cell counts of leukocytes subpopulations are demonstrating to have an important value in predicting outcome in severe infections. We evaluated here the render of leukogram counts to predict outcome in patients with ventilator-associated pneumonia (VAP) caused by Staphylococcus aureus. …”
Get full text

Towards Elimination of Mother-to-Child Transmission of HIV: The Impact of a Rapid Results Initiative in Nyanza Province, Kenya by Lisa L. Dillabaugh, Jayne Lewis Kulzer, Kevin Owuor, Valerie Ndege, Arbogast Oyanga, Evelyne Ngugi, Starley B. Shade, Elizabeth Bukusi, Craig R. Cohen

“…Significant improvement in PMTCT services can be achieved through introduction of an RRI, which appears to lead to sustained benefits for pregnant HIV-infected women and their infants.…”
Get full text