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13601
Hepatitis C Virus–Pediatric and Adult Perspectives in the Current Decade
Published 2024-12-01“…Hepatitis C virus (HCV) infects both pediatric and adult populations and is an important cause of chronic liver disease worldwide. …”
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13602
KSHV hijacks the antiviral kinase IKKε to initiate lytic replication.
Published 2025-01-01“…IKKε is a traditional antiviral kinase known for positively regulating the production of type I interferon (IFN) and the expression of IFN-stimulated genes (ISGs) during various virus infections. However, through an inhibitor screen targeting cellular kinases, we found that IKKε plays a crucial role in the lytic replication of Kaposi's sarcoma-associated herpesvirus (KSHV). …”
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13603
Kennel Disinfectants for Microsporum canis and Trichophyton sp.
Published 2015-01-01“…The antifungal efficacy of commonly used kennel disinfectants for large surfaces was tested using naturally infective material from untreated animals (M. canis and Trichophyton sp.) soaked and macerated but unfiltered leaving visible fluorescing hairs and/or scales in the test inoculum to create a robust challenge. …”
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13604
The silent menace: Worm bezoar causing acute intestinal obstruction
Published 2025-01-01“…In contrast to developed nations, where the usual causes of obstruction are adhesions, strictures, and metabolic derangements, infective etiologies, like tuberculosis and parasitic infestations, are more common in developing countries. …”
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13605
Cell-free assays reveal that the HIV-1 capsid protects reverse transcripts from cGAS immune sensing.
Published 2025-01-01“…Strikingly, the capsid inhibitor lenacapavir also disrupted viral cores and dramatically potentiated cGAS activity, both in vitro and in cellular infections. Our results provide biochemical evidence that the HIV-1 capsid lattice conceals the genome from cGAS and that chemical or physical disruption of the viral core can expose HIV-1 DNA and activate innate immune signaling.…”
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13606
NK Cell Subtypes as Regulators of Autoimmune Liver Disease
Published 2016-01-01“…As major components of innate immunity, NK cells not only exert cell-mediated cytotoxicity to destroy tumors or infected cells, but also act to regulate the functions of other cells in the immune system by secreting cytokines and chemokines. …”
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13607
Multicentric Castleman's Disease in a Hepatitis C-Positive Intravenous Drug User: A Case Report
Published 2011-01-01“…A 46-year-old male with untreated hepatitis C and a 16-year history of intravenous drug use presented with pleuritic chest pain and bony pain in the knee, hip, and lower back, on a background of unexplained weight loss of 40 kilograms, fevers, night sweats, and repeated infections over the last two years. Examination discovered tender hepatomegaly, a warm right knee effusion, and painless lymphadenopathy. …”
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13608
Prevalence of Multidrug-Resistant Klebsiella pneumoniae Clinical Isolates in Nepal
Published 2022-01-01“…Three electronic databases: PubMed, Google Scholar, and Research4Life were used to search publications specifying K. pneumoniae infections and/or their MDR status from January 2015 to October 2021. …”
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13609
Amp-CKlebsiella-Induced Chorioamnionitis and Associated Abnormalities in Cardiotocography: A Case Report with a Narrative Review
Published 2022-01-01“…Introduction. Infections caused by multidrug-resistant organisms are on the rise in obstetric patients. …”
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13610
Alginate Nanoparticles Containing Cuminum cyminum and Zataria multiflora Essential Oils with Promising Anticancer and Antibacterial Effects
Published 2024-01-01“…Cancer and bacterial infections are major global health concerns driving the need for innovative medicines. …”
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13611
Facial Lichen Planus Pigmentosus-Like Pigmentation Induced by Vicks VapoRub: A Case Report
Published 2025-01-01“…Vicks VapoRub is an inhalant ointment frequently used to relieve symptoms of upper respiratory tract infections. We report a case of lichen planus pigmentosus induced by Vicks VapoRub and successfully treated with topical tacrolimus 0.1% cream.Keywords: lichen planus pigmentosus, Vicks VapoRub, tacrolimus, facial hyperpigmentation, lichen planus…”
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13612
Antibacterial Effects of the Novel Blue Laser and Erbium Chromium Laser on Enterococcus Faecalis in Root Canal Dentin with Different Thicknesses
Published 2022-01-01“…It seems that these lasers can be used as an adjunct to conventional chemical methods in cleaning infected canals.…”
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13613
Optimal Control and Cost-Effectiveness Strategies of Malaria Transmission with Impact of Climate Variability
Published 2022-01-01“…Secondly, using the maximum principle of Pontryagin, the optimal malaria reduction strategies are described with three control measures, namely, treated bed nets, infected human treatment, and indoor residual spraying. …”
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13614
Evaluation of some properties of elastomeric dental impression materials after disinfection
Published 2019-06-01“… Backgrounds and objectives: Dental impressions present a risk to spread infections among dental practitioners and should be disinfected to prevent the spread of these microorganisms. …”
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13615
Profile of STING agonist and inhibitor research: a bibliometric analysis
Published 2025-02-01“…Its activation has shown great potential in anti-tumor and anti-infective therapies, with STING agonists emerging as a promising approach in cancer immunotherapy in recent years. …”
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13616
The Effectiveness of Medical Podcasts in Raising Women’s Health Awareness
Published 2024-05-01“…Online pretests and posttests, one based on a podcast episode regarding vaginal infections, were used to assess changes in knowledge level pre– and post–podcast listening. …”
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13617
Ignoring Gender-Based Immunometabolic Reprograming, a Risky Business in Immune-Based Precision Medicine
Published 2025-01-01“…On the other hand, reproductive-age females also show a more potent immune response against infections and vaccines than their age-matched males—furthermore, some immune-based therapies, including immune checkpoint inhibitors (ICIs), show gender-based efficacy and adverse events. …”
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13618
Tigecycline-induced acute pancreatitis with electrocardiogram changes in renal insufficiency elderly
Published 2024-12-01“…This medicine is commonly used to treat complicated skin and intraabdominal infections as well as community-acquired pneumonia. …”
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13619
Antiretroviral Treatment Adherence: Knowledge and Experiences among Adolescents and Young Adults in Soweto, South Africa
Published 2017-01-01“…Four focus group discussions (FGDs) and eight in-depth interviews (IDIs) were conducted with HIV-infected 15–25-year-old ART recipients. Transcripts were coded thematically. …”
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13620
Vaccines in the fight against antimicrobial resistance – perspectives from South Africa
Published 2024-09-01“…Behavioural factors, such as purchasing antibiotics without a prescription from a registered healthcare professional, not completing the prescribed course or overly prolonged courses of antibiotics, using antibiotics to treat viral infections, lack of access to quality antibiotics, and the proliferation of substandard or falsified (SF) drugs, have also been identified as significant contributors to AMR. …”
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