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13521
A systematised review and evidence synthesis on the broader societal impact of vaccines against Salmonella
Published 2025-02-01“…Despite variations in study design, methodology, and study quality, salmonellae infections were largely associated with negative broader societal impacts, including detriments in childhood physical development (very weak association), childhood educational development (strong to very strong association), household security (moderate association), public health spending (moderate association), and national income (moderate to strong association). …”
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13522
Development of an in vitro triculture model of intestine inflammation to assess the immunomodulatory properties of cassava and roselle, two African green leafy vegetables
Published 2025-03-01“…In sub-Saharan Africa, frequent infections and enteric dysfunction can cause intestinal inflammation that is associated with stunting. …”
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13523
Growth and Neurodevelopmental Outcome in Preterm LBW Infants with Sepsis in India: A Prospective Cohort
Published 2018-01-01“…Conclusion. Neonatal infections are associated with the abnormal neurodevelopmental outcomes in LBW infants but there was no significant difference at growth outcome at 9 to 15 months of corrected age between both groups.…”
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13524
Association between Severe Dehydration in Rotavirus Diarrhea and Exclusive Breastfeeding among Infants at Dr. Hasan Sadikin General Hospital, Bandung, Indonesia
Published 2015-01-01“…Infants who are exclusively breastfed develop fewer infections and have less severe illnesses. This study aimed to determine association between severe dehydration in rotavirus diarrhea and exclusive breastfeeding. …”
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13525
Potential use of peptides mimicking CRAC/CARC domains as antivirulence therapies to inhibit RTX toxins activities
Published 2024-11-01“…In recent years, research efforts have increased to develop new therapeutics aimed at combating antibiotic-resistant bacterial infections. These efforts focus on inhibiting the virulence factors bacteria secrete to proliferate. …”
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13526
IL-18 biology in severe asthma
Published 2024-11-01“…Furthermore, we discuss the emerging evidence of IL-18’s involvement in autoimmunity and highlight potential therapeutic targets within the IL-18 and inflammasome pathways in severe asthma patients with evidence of infections and airway autoimmune responses. By synthesizing recent advancements and ongoing research, this review underscores the importance of IL-18 as a potential novel therapeutic target in the treatment of severe asthma and other related conditions.…”
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13527
Aspergillus fumigatus ctf1–a novel zinc finger transcription factor involved in azole resistance
Published 2025-02-01“…Elucidating the mechanisms underlying antifungal resistance in Aspergillus fumigatus, discovering new antifungal targets, and developing drugs to inhibit resistance are the key approaches to treating A. fumigatus infections. Here, we investigated the function of ctf1 (AFUA_1G03800), a gene encoding a C6 transcription factor. …”
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13528
Determination of whole genome sequence of human cytomegalovirus circulating in Japan and discovery of geographic genome structure in UL148 gene
Published 2025-03-01“…HCMV is generally asymptomatic but causes severe disease in immunocompromised patients or infants who are congenitally infected. Recent advances in sequencing technology have led to the rapid expansion of the HCMV genetic database, providing a comprehensive resource for studying viral genetics. …”
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13529
Lesion Distribution and Epidemiology of Mycobacterium bovis in Elk and White-Tailed Deer in South-Western Manitoba, Canada
Published 2011-01-01“…Period prevalence in elk was approximately six times higher than deer, suggesting a significant reservoir role for elk, but that infected deer may also be involved. Prevalence was consistently higher in elk compared to deer in a small core area and prevalence declines since 2003 are likely due to a combination of management factors instituted during that time. …”
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13530
The occupational roles of hospitalized people due to Acquired Immune Deficiency Syndrome
Published 2014-04-01“…The casuistry was composed by 40 HIV-positive persons interned, subdivided in three groups considering diagnosis time; the control group was composed by 12 persons, not infected and not interned. Quantitative data were collected by means of the application of the protocol “List of Identification of Occupational Roles”, validated in Brazil, and analyzed by Fisher Exact Test. …”
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13531
A physiologically-based pharmacokinetic model for the antibiotic ertapenem
Published 2015-09-01“…Ertapenem is an antibiotic commonly used to treat a broad spectrum of infections, which is part of a broader class of antibiotics called carbapenem. …”
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13532
Using Cell-Based Strategies to Break the Link between Bronchopulmonary Dysplasia and the Development of Chronic Lung Disease in Later Life
Published 2013-01-01“…Therefore, it is possible that early-life pulmonary insults, such as extreme prematurity and BPD, may increase the risk of COPD later in life, especially if exposed to secondary challenges such as respiratory infections and/or smoking. Recent advances in our understanding of stem/progenitor cells and their potential to repair damaged organs offer the possibility of cell-based treatments for neonatal and adult lung injuries. …”
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13533
A Review on Synthesis, Optimization, Mechanism, Characterization, and Antibacterial Application of Silver Nanoparticles Synthesized from Plants
Published 2020-01-01“…Furthermore, a thorough discussion on the recent advances in the application of AgNPs synthesized from plant as therapeutic agent against bacterial infections was made.…”
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13534
Acceptability and completeness of vaccination schedules recommended for transgender women and travestis in the city of São Paulo, Brazil: a cross-sectional study, 2019-2020
Published 2025-01-01“…Conclusion Despite high adherence, the low completion of vaccination schedules highlighted the need for diversified strategies to improve vaccination coverage and reduce the prevalence of vaccine-preventable sexually transmitted infections in this population.…”
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13535
Serum Calprotectin: An Antimicrobial Peptide as a New Marker For the Diagnosis of Sepsis in Very Low Birth Weight Newborns
Published 2011-01-01“…To determine the diagnostic utility of serum calprotectin, a mediator of innate immune response against infections, we performed a multicenter study involving newborns with a birth weight <1500 g and a postnatal age >72 hours of life. …”
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13536
Intestinal permeability, food antigens and the microbiome: a multifaceted perspective
Published 2025-01-01“…Nevertheless, this frail balance might be disrupted for instance by westernized dietary habits, infections, pollution or exposure to antibiotics, thus diminishing protective immunity and leading to the onset of chronic diseases. …”
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13537
On the Stability and Equilibrium Points of Multistaged SI(n)R Epidemic Models
Published 2015-01-01“…The physical interpretation of the model is that the dynamics of the disease exhibits different stages in which the infectivity and the mortality rates vary as the individual numbers go through the process of recovery, each stage with a characteristic average time.…”
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13538
Eastern equine encephalitis virus: Pathogenesis, immune response, and clinical manifestations
Published 2025-03-01“…Eastern equine encephalitis virus (EEEV) is a lethal Alphavirus transmitted by Culiseta melanura mosquitoes that primarily cycles between birds. Although rare, infections in humans and horses are associated with high mortality rates and severe neurological effects. …”
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13539
Numerical simulation and dynamical system for solving biomathematical model with optimal control
Published 2025-03-01“…Our statistical analysis has revealed that social isolation between potentially infected carriers of the illness and healthy people may be able to stop or slow the illness from spreading. …”
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13540
CCR5-ligand decorated rilpivirine lipid-based nanoparticles for sustained antiretroviral responses
Published 2025-01-01“…The CCR5-mediated LBNP cell uptake and retention reduce HIV-1 replication in human monocyte-derived macrophages and infected humanized mice (hu mice). Focused ultrasound with microbubbles mediated blood brain barrier (BBB) disruption allows the CCR5-targeted LBNP to penetrate the BBB and reach brain myeloid cells. …”
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