Ophiostomatoid fungi associated with Ips subelongatus, including eight new species from northeastern China by Zheng Wang, Ya Liu, Huimin Wang, Xianjing Meng, Xuewei Liu, Cony Decock, Xingyao Zhang, Quan Lu

“…Abstract Ips subelongatus is a major pest that infects larch plantations over large areas of northern and northeastern China. …”
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Elevated VEGF Levels in Pulmonary Edema Fluid and PBMCs from Patients with Acute Hantavirus Pulmonary Syndrome by Irina Gavrilovskaya, Elena Gorbunova, Frederick Koster, Erich Mackow

“…Hantaviruses alter the normal regulation of β3 integrins that restrict VEGF-directed permeability and hantavirus infected endothelial cells are hyperresponsive to the permeabilizing effects of VEGF. …”
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Case-Control Pilot Study on Acute Diarrheal Disease in a Geographically Defined Pediatric Population in a Middle Income Country by Ana E. Farfán-García, Chengxian Zhang, Aamer Imdad, Monica Y. Arias-Guerrero, Nayibe T. Sánchez-Alvarez, Rikhil Shah, Junaid Iqbal, Maria E. Tamborski, Oscar G. Gómez-Duarte

“…The E. coli pathogens were 18.8% of all infections making them the most frequent pathogens. …”
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Psychological Impacts among Older and Younger People Living with HIV/AIDS in Nanning, China by Hongjie Liu, Xin He, Judith A. Levy, Yongfang Xu, Chunpeng Zang, Xinqin Lin

“…Intervention programs dedicated to improving mental health and quality of life are greatly needed for HIV infected older adults.…”
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Syzygium aromaticum extract mediated, sustainable silver nanoparticle synergetic with heterocyclic antibiotic clarithromycin and their antimicrobial activities by Zehra Edis, Zehra Edis, Samir Haj Bloukh, Samir Haj Bloukh, Akram A. Ashames, Akram A. Ashames, Moawia M. Al-Tabakha, Moawia M. Al-Tabakha, Moyad J. S. A. Shahwan, Moyad J. S. A. Shahwan, Hamed Abu Sara, Hamed Abu Sara, Sai H. S. Boddu, Sai H. S. Boddu, Sohaib N. Khan, Sohaib N. Khan, Ibrahim Haj Bloukh, Maram Eladdasy, Somayeh Sadeghi, Haneen Alkubaisi, Iman Haj Bloukh, Nageeb A. G. M. Hassan, Nageeb A. G. M. Hassan

“…Microorganisms are becoming resistant to drugs and antimicrobials, making it a significantly critical global issue. Nosocomial infections are resulting in alarmingly increasing rates of morbidity and mortality. …”
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Global scenario of silica-associated diseases: A review on emerging pathophysiology of silicosis and potential therapeutic regimes by Prasad Sherekar, Sanvidhan G. Suke, Archana Dhok, Srikant Malegaonkar, Shrikrishna A. Dhale

“…Other crystalline silica-induced pulmonary disorders include a predisposition to mycobacterial infections, obstructive airway diseases, idiopathic pulmonary fibrosis, and lung cancer. …”
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Downregulation of mPGES-1 Expression via EGR1 Plays an Important Role in Inhibition of Caffeine on PGE2 Synthesis of HBx(+) Hepatocytes by Yan Ma, Xiaoqian Wang, Nanhong Tang

“…The results indicate that caffeine could effectively reduce PGE2 synthesis in HBx(+) hepatocytes by specifically blocking the PPARγ-EGR1-mPGES-1 pathway, thereby providing a new evidence of molecular biology for the hypothesis that drinking coffee is beneficial to HBV-infected patients.…”
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Hemophagocytic Lymphohistiocytosis in a Patient with Classical Hodgkin Lymphoma by G. Hyun, K. J. Robbins, N. Wilgus, L. Grosso, S. D. Goyal

“…Hemophagocytic lymphohistiocytosis (HLH) is a rare hyperinflammatory syndrome that can be associated with inherited genetic mutations, malignancy, autoimmune disorders, and viral infections. Though the pathogenesis is not fully known, HLH is understood to be a reactive process in the setting of uncontrolled activation of macrophages, CD8+ cytotoxic lymphocytes, and other immune cells. …”
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Two-centers machine learning analysis for predicting acid-fast bacilli results in tuberculosis sputum tests by Jichong Zhu, Yong Zhao, Chengqian Huang, Chenxing Zhou, Shaofeng Wu, Tianyou Chen, Xinli Zhan

“…Background: Tuberculosis (TB) is a chronic respiratory infectious disease caused by Mycobacterium tuberculosis, typically diagnosed through sputum smear microscopy for acid-fast bacilli (AFB) to assess the infectivity of TB. Methods: This study enrolled 769 patients, including 641 patients from the First Affiliated Hospital of Guangxi Medical University as the training group, and 128 patients from Guangxi Hospital of the First Affiliated Hospital of Sun Yat-sen University as the validation group. …”
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Strong immune responses and robust protection following a novel protein in adjuvant tuberculosis vaccine candidate by Marcellus Korompis, Christopher J De Voss, Shuailin Li, Alexandre Richard, Salem Salman Almujri, Alberta Ateere, Géraldine Frank, Céline Lemoine, Helen McShane, Elena Stylianou

“…M72/AS01E, demonstrated 49.7% efficacy in preventing active TB in latently infected adults, indicating that protective immunity through subunit vaccines is possible. …”
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Genetic analysis reveals the genetic diversity and zoonotic potential of Streptococcus dysgalactiae isolates from sheep by Ilona Stefańska, Ewelina Kwiecień, Anna Didkowska, Magdalena Kizerwetter-Świda, Dorota Chrobak-Chmiel, Agnieszka Sałamaszyńska-Guz, Piotr Żmuda, Krzysztof Anusz, Magdalena Rzewuska

“…Phylogenetic analysis showed that studied ovine isolates grouped together with human S. dysgalactiae isolates from the cases of zoonotic infections. Moreover, some ovine isolates shared identical STs and emm gene sequences with human non-invasive and invasive S. dysgalactiae strains. …”
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Synthesis, characterization, In silico, and In vitro studies of CuS–ZnO nanocomposite using mushroom extract by S. Anbazhagi, A. Murugesan, M. Paramanantham, K. Chinnaiah, Karthik Kannan, Nadezhda Palko, K. Gurushankar

“…Clavilactone D could be more effective against fungal infections. Hence, this study explores the antimicrobial and Vitro studies green-synthesized CuS–ZnO nanocomposite and examined the responsible major biocompound for activity through the theoretical study. …”
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Elucidation of peptide screen for targeted identification of Yersinia pestis by nano-liquid chromatography tandem mass spectrometry by Priya Rani, Syed Imteyaz Alam, Sandeep Singh, Subodh Kumar

“…Plague bacteria are usually transmitted to humans through the bite of an infected rat flea. Earlier studies have indicated that Y. pestis can survive in environmental matrices e.g. water and soil. …”
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The Causative Pathogen Determines the Inflammatory Profile in Cerebrospinal Fluid and Outcome in Patients with Bacterial Meningitis by Denis Grandgirard, Rahel Gäumann, Boubacar Coulibaly, Jean-Pierre Dangy, Ali Sie, Thomas Junghanss, Hans Schudel, Gerd Pluschke, Stephen L. Leib

“…The brain’s inflammatory response to the infecting pathogen determines the outcome of bacterial meningitis (BM), for example, the associated mortality and the extent of brain injury. …”
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RIOK1/2 Negatively Regulates the Antiviral Response by Targeting TBK1 in Yellow Catfish (<i>Pelteobagrus fulvidraco</i>) by Kejun Liu, Jiayang Huang, Yuting Gui, Qian Li, Lei Zhang, Shuting Xiong

“…Additionally, PfRIOK1 and PfRIOK2 could inhibit PfTBK1-mediated antiviral responses in infected cells. These results suggest that PfRIOK1 and PfRIOK2 act as negative regulators of the IFN response in yellow catfish, providing new insights into the regulatory mechanisms of fish innate immunity and offering target molecules for molecular design breeding in aquaculture.…”
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Prevalence and methodologies for detection, characterization and subtyping of Listeria monocytogenes and L. ivanovii in foods and environmental sources by Jin-Qiang Chen, Patrick Regan, Pongpan Laksanalamai, Stephanie Healey, Zonglin Hu

“…L. ivanovii, which is closely related to L. monocytogenes, is also widely distributed in nature and infects mainly warm-blooded ruminants, causing economic loss. …”
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TNF-α Promotes IFN-γ-Induced CD40 Expression and Antigen Process in Myb-Transformed Hematological Cells by Wenyi Gu, Jiezhong Chen, Lei Yang, Kong-Nan Zhao

“…Tumour necrosis factor-α, interferon-γ and interleukin-4 are critical cytokines in regulating the immune responses against infections and tumours. In this study, we investigated the effects of three cytokines on CD40 expression in Myb-transformed hematological cells and their regulatory roles in promoting these cells into dendritic cells. …”
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Phosphorylation of S‐S‐S Motif in Nuclear Export Protein (NEP) Plays a Critical Role in Viral Ribonucleoprotein (vRNP) Nuclear Export of Influenza A and B Viruses by Xiaokun Liu, Cha Yang, Xian Lin, Xiaomei Sun, Huanchun Chen, Qiang Zhang, Meilin Jin

“…These mutations significantly inhibited vRNPs nuclear export are founded, decreased viral infectivity and attenuated virulence in mice. In addition, inhibition or knockout of ATM or CK2, two predicated Ser/Thr protein kinases that phosphorylate the S‐S‐S motif, impedes vRNP nuclear export and virus replication in cells and reduces the virulence in vivo. …”
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Surgical treatment and outcomes in aortic valve endocarditis and perivalvular abscesses by Ellelan Degife, Alyssa Morrison, Syed Bin Usman Mahmood, Sigurdur Ragnarsson, Andrea Amabile, Roland Assi, Prashanth Vallabjoyshula, Arnar Geirsson

“…Abstract Patients with aortic root abscesses experience increased morbidity and mortality compared to those without abscess in aortic valve infective endocarditis. The superior intervention for patients with aortic root abscess is not determined. …”
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In Situ Aqueous Spice Extract-Based Antifungal Lock Strategy for Salvage of Foley’s Catheter Biofouled with <i>Candida albicans</i> Biofilm Gel by Bindu Sadanandan, Vaniyamparambath Vijayalakshmi, Kalidas Shetty, Adithya Rathish, Harshala Shivkumar, Malavika Gundreddy, Nikhil Kumar Kagganti Narendra, Nethra Machamada Devaiah

“…<i>Candida</i> forms a gel-like biofilm in the Foley’s catheter (FC) causing tenacious biofouling and severe urinary tract infections (UTIs). For the first time, a spice extract-based antifungal lock therapy (ALT) has been developed to inhibit the <i>Candida albicans</i> gel matrix in FC. …”
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