Characterization of Active Compounds of Different Garlic (Allium sativum L.) Cultivars by Szychowski Konrad A., Rybczyńska-Tkaczyk Kamila, Gaweł-Bęben Katarzyna, Świeca Michał, Karaś Monika, Jakubczyk Anna, Matysiak Magdalena, Binduga Urszula E., Gmiński Jan

“…Garlic (Allium sativum L.) has a reputation as a therapeutic agent for many different diseases such as microbial infections, hypertension, hypercholesterolaemia, diabetes, atherosclerosis and cancer. …”
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An environmental isolate of Pseudomonas, 20EI1, reduces Aspergillus flavus growth in an iron-dependent manner and alters secondary metabolism by Elizabeth M. Wyman, W. Scott Grayburn, Matthew K. Gilbert, Matthew D. Lebar, Jessica M. Lohmar, Jeffrey W. Cary, Thomas J. C. Sauters, Antonis Rokas, Ana M. Calvo

“…IntroductionAspergillus flavus is an opportunistic pathogenic fungus that infects oilseed crops worldwide. When colonizing plants, it produces mycotoxins, including carcinogenic compounds such as aflatoxins. …”
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Evaluation of Antibiotic Resistance and Biofilm Production among Clinical Strain Isolated from Medical Devices by Veronica Folliero, Gianluigi Franci, Federica Dell’Annunziata, Rosa Giugliano, Francesco Foglia, Rossella Sperlongano, Anna De Filippis, Emiliana Finamore, Massimiliano Galdiero

“…Prolonged periods of implantation carry a high risk of device-related infections (DRIs). Patients with DRIs often have negative outcomes following the failure of antibiotic treatment. …”
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Mid-Term to Long-Term Outcomes of Total Hip Arthroplasty Using a Cementless Trochanteric Sparing Short Stem Through Direct Anterior Approach: A Single-Center Study by Seyed Mohammad Javad Mortazavi, MD, Pouya Tabatabaei Irani, MD, Mohammad Poursalehian, MD, Mahsa Mahanrad, MD, Peyman Mirghaderi, MD, Mohammadreza Razzaghof, MD, Sadegh Saberi, MD

“…Stem revisions were performed in 20 hips, primarily due to periprosthetic fractures followed by periprosthetic joint infections and recurrent dislocations. The clinical outcomes showed significant improvements in HHS, WOMAC Index, and VAS pain scores. …”
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Gut microbiota and bacterial associations in monkeys with gastrointestinal diseases in the setting of helminth infestation by V. A. Kalashnikova, T. P. Egorova, A. V. Demerchyan, V. I. Polyakova, Y. I. Lenshina, D. A. Ilyazyants, I. M. Arshba

“…One of the topical issues of current primatology is spontaneous pathology in monkeys, primarily gastrointestinal infections, which are the leading ones in the morbidity and mortality patterns of the animals raised in captivity. …”
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Development and validation of a LAMP-based method for rapid and reliable detection of Xanthomonas albilineans, the causal agent of sugarcane leaf scald by Moutoshi Chakraborty, Moutoshi Chakraborty, Shamsul Arafin Bhuiyan, Shamsul Arafin Bhuiyan, Simon Strachan, Simon Strachan, Muhammad J. A. Shiddiky, Nam-Trung Nguyen, Rebecca Ford, Rebecca Ford

“…Sugarcane samples from infected plants were subjected to heat lysis, followed by loop-mediated isothermal amplification (LAMP)-based fluorescence and colorimetric quantification within a single microcentrifuge tube.ResultsThe method exhibited exceptional detection sensitivity (detecting as low as 1 cell/μL), reproducibility [with a standard deviation (SD) of <5% for n = 3], and a broad linear dynamic range (10 pM to 1 aM or 107–100 copies/μL, r = 0.99). …”
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Adaptive evolution of stress response genes in parasites aligns with host niche diversity by Armando J. Cruz-Laufer, Maarten P. M. Vanhove, Lutz Bachmann, Maxwell Barson, Hassan Bassirou, Arnold R. Bitja Nyom, Mare Geraerts, Christoph Hahn, Tine Huyse, Gyrhaiss Kapepula Kasembele, Samuel Njom, Philipp Resl, Karen Smeets, Nikol Kmentová

“…We also observed positive selection patterns in genes related to mitochondrial protein import (H sp) and behaviour (For) in species of Cichlidogyrus infecting East African cichlids—a host lineage under adaptive radiation. …”
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The microbiome of Total Suspended Particles and its influence on the respiratory microbiome of healthy office workers by Giulia Solazzo, Sabrina Rovelli, Simona Iodice, Matthew Chung, Michael Frimpong, Valentina Bollati, Luca Ferrari, Elodie Ghedin

“…The indoor samples had higher relative abundance of environmental bacteria often associated with opportunistic infections like Paracoccus sp., as well as respiratory bacteria such as Staphylococcus aureus and Klebsiella pneumoniae. …”
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Plasma IL-6/IL-10 Ratio and IL-8, LDH, and HBDH Level Predict the Severity and the Risk of Death in AIDS Patients with Pneumocystis Pneumonia by Jia Sun, Junwei Su, Yirui Xie, Michael T. Yin, Ying Huang, Lijun Xu, Qihui Zhou, Biao Zhu

“…Biomarkers including clinical parameters and plasma inflammatory cytokines were assessed in 32 HIV-infected patients with Pneumocystis pneumonia (PCP) at time of admission. …”
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Fragment optimized chalcone derivatives targeting OmpA protein as a therapeutic approach against multidrug resistant Acinetobacter baumannii by Muhammad Naveed, Amina Abid, Tariq Aziz, Ayesha Saleem, Arooj Arshad, Khushbakht Javed, Hafiz Muzzammel Rehman, Ghulam Nabi, Mitub Al-harbi, Abdullah F. Alasmari

“…Abstract Acinetobacter baumannii is a notorious pathogen associated with life-threatening infections, with its outer membrane protein A (OmpA) being a key contributor to its pathogenicity by targeting epithelial cell apoptosis. …”
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Therapeutic efficacy of LysGH15 against necrotising pneumonia caused by Staphylococcus aureus in a rabbit model by Bowei Zhang, Liran Song, Yongran Wang, Meimei Zhang, Chong Chen, Hui Ning, Li Wang, Cao Qiu, Xinwu Wang, Changjiang Sun, Xin Feng, Wenyu Han, Wenyu Han, Bin Wang, Yalu Ji, Jingmin Gu, Jingmin Gu

“…In addition, LysGH15 treatment alleviated lung tissue damage in infected rabbits and significantly reduced the levels of Panton-Valentine leukocidin (PVL), alpha-toxin (Hla), and the cytokines IFN-γ, TNF-α, and IL-8 in their lung tissues, similar to those in rabbits treated with linezolid.DiscussionThese results suggest that LysGH15 has the potential to be used as a novel antimicrobial agent for the treatment of necrotising pneumonia caused by S. aureus.…”
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Seasonal activities, morphological characteristics, and veterinary importance of Haemaphysalis mageshimaensis in Ishigaki and Yonaguni, Okinawa, Japan by Satoko Nakao, Thillaiampalam Sivakumar, Yuko Takakuwa, Hajime Suzuki, Keiichiro Ohta, Keiko Nakamura, Osamu Tsuha, Yuzuru Ikehara, Sanae Ikehara, Syota Ohki, Mizue Inumaru, Yukiko Higa, Rika Umemiya-Shirafuji, Naoaki Yokoyama

“…PCR screening of DNAs from selected ticks showed that 9.7 % of H. mageshimaensis and 25 % of H. longicornis were infected with Theileria orientalis. Our findings indicate that H. mageshimaensis has overtaken H. longicornis as the dominant species in Yaeyama, highlighting the need for year-round tick control measures.…”
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NTHi killing activity is reduced in COPD patients and is associated with a differential microbiome by Vancheswaran Gopalakrishnan, Ben Sparklin, Jung Hwan Kim, Jerome Bouquet, Margaret Kehl, Tara Kenny, Christopher Morehouse, Carolina Caceres, Paul Warrener, Ventzislava A. Hristova, Susan Wilson, Harini Shandilya, Arnita Barnes, Alexey Ruzin, Junmin Wang, Lisa Oberg, Bastian Angermann, Christopher McCrae, Adam Platt, Daniel Muthas, Sonja Hess, Christine Tkaczyk, Bret R. Sellman, Kristoffer Ostridge, Maria G. Belvisi, Tom M. A. Wilkinson, Karl J. Staples, Antonio DiGiandomenico, on behalf of the MICA II Study Group

“…Non-typeable Haemophilus influenzae (NTHi) lung infections are common in COPD, promoting frequent exacerbations and accelerated lung function decline. …”
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Evaluating ChatGPT-4's performance on oral and maxillofacial queries: Chain of Thought and standard method by Kaiyuan Ji, Zhihan Wu, Jing Han, Guangtao Zhai, Guangtao Zhai, Jiannan Liu

“…These questions encompass 12 areas of oral and maxillofacial surgery, including Prosthodontics, Pediatric Dentistry, Maxillofacial Tumors and Salivary Gland Diseases, and maxillofacial Infections.ResultsUsing CoT approach, ChatGPT-4 exhibited marked enhancements in accuracy, structure, completeness, professionalism, and overall impression for open-ended questions, revealing statistically significant differences compared to its performance on general oral and maxillofacial inquiries. …”
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Population genetics of Glossina palpalis gambiensis in the sleeping sickness focus of Boffa (Guinea) before and after eight years of vector control: no effect of control despite a... by Kagbadouno, Moise S, Séré, Modou, Ségard, Adeline, Camara, Abdoulaye Dansy, Camara, Mamadou, Bucheton, Bruno, Bart, Jean-Mathieu, Courtin, Fabrice, De Meeûs, Thierry, Ravel, Sophie

“…We thus recommend the pursuit of vector control measures with the same strategy, through the joint effect of VCC and medical surveys and treatments, in order to protect human populations from HAT infections until the disease can be considered as entirely eradicated from the focus.…”
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Plasma Fatty Acids in Zambian Adults with HIV/AIDS: Relation to Dietary Intake and Cardiovascular Risk Factors by Christopher K. Nyirenda, Edmond K. Kabagambe, John R. Koethe, James N. Kiage, Benjamin H. Chi, Patrick Musonda, Meridith Blevins, Claire N. Bosire, Michael Y. Tsai, Douglas C. Heimburger

“…In a cross-sectional study among 210 antiretroviral therapy-naïve HIV-infected adults from Lusaka, Zambia, we collected data on medical history and dietary intake using 24 hr DR. …”
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First Detection and Genomic Characterization of Linezolid-Resistant <i>Enterococcus faecalis</i> Clinical Isolates in Bulgaria by Tanya V. Strateva, Preslava Hristova, Temenuga J. Stoeva, Hristina Hitkova, Slavil Peykov

“…Linezolid is an oxazolidinone antibiotic and is considered a last-resort treatment option for serious infections caused by problematic Gram-positive pathogens, including vancomycin-resistant enterococci. …”
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Multiplex one-step RT‒qPCR assays for simultaneous detection of AMDV, MEV and CDV by Zhi Cao, Hang Xu, Xinru Zhao, Ke Zhang, Dehua Yin, Shuai Ma, Wenling Li, Siyu Li, Jianwei Ren, Jianxin Wen

“…In clinical practice, aleutian mink disease virus (AMDV), mink enteritis virus (MEV) and canine distemper virus (CDV) are common mixed infections, and they have similar clinical clinical signs, such as diarrhoea. …”
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Lactoferrin: a secret weapon in the war against pathogenic bacteria by Lucero Ruiz-Mazón, Gerardo Ramírez-Rico, Mireya de la Garza

“…Because of its effectiveness, accessibility, low cost, and nontoxicity, Lf could be a promising alternative for preventing or treating infections in animals and humans.…”
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Evaluation of the antibacterial activity of essential oils from oregano (Origanum vulgare) against Escherichia coli strains isolated from meat products by L. Brito-Junior, H. C. Brito, M. M. Simões, B. Santos, F. M. C. Marques, M. A. A. Medeiros, M. S. Alves, J. H. A. Farias, C. T. Pereira, A. F. Diniz, A. A. Oliveira-Filho, V. L. R. Vilela

“…In short, O. vulgare essential oil exhibited antimicrobial potential against E. coli strains isolated from meat products, suggesting which, upon more detailed investigations, could be used both in isolation or in combination with synthetic antibiotics to combat infections caused by this pathogen.…”
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