How do serum cytokine levels change in myocarditis and inflammatory dilated cardiomyopathy relative to healthy individuals? A protocol for a systematic review and meta-analysis by Romuald Wojnicz, Piotr Lewandowski, Maciej Baron, Marcin A Rojek, Marcin Goławski, Karol Krystek, Magdalena Żegleń, Pascal Zytkiewicz, Jakub Kancerek, Klaudia Gabriela Lis, Jakub Warecki, Jakub Kufel, Kamila Kuśpiel

“…Introduction Myocarditis is an inflammatory heart disease resulting from infections, toxic exposures or autoimmune reactions. …”
Get full text

Inflammation-Related Mechanisms in Chronic Kidney Disease Prediction, Progression, and Outcome by Simona Mihai, Elena Codrici, Ionela Daniela Popescu, Ana-Maria Enciu, Lucian Albulescu, Laura Georgiana Necula, Cristina Mambet, Gabriela Anton, Cristiana Tanase

“…There are many factors that contribute to the setting of the inflammatory status in CKD, including increased production of proinflammatory cytokines, oxidative stress and acidosis, chronic and recurrent infections, altered metabolism of adipose tissue, and last but not least, gut microbiota dysbiosis, an underestimated source of microinflammation. …”
Get full text

Inhibition of STING-mediated type I IFN signaling by African swine fever virus DP71L by Lakmal Ranathunga, Sachini Abesinghe, Ji-Won Cha, Niranjan Dodantenna, Kiramage Chathuranga, Asela Weerawardhana, D. K. Haluwana, Nuwan Gamage, Jong-Soo Lee

“…Consistently, knockdown of DP71L enhanced antiviral gene expression in ASFV-infected cells. Taken together, these results highlight the important role of DP71L with respect to inhibition of interferon responses and provide guidance for a better understanding of ASFV pathogenesis and the development of live attenuated ASFV vaccines.…”
Get full text

Identification of a New Pentafluorosulfanyl-Substituted Chalcone with Activity Against Hepatoma and Human Parasites by Alessandra Viperino, Michael Höpfner, Nicole Edel, Ibrahim S. Al Nasr, Waleed S. Koko, Tariq A. Khan, Imen Ben Abdelmalek, Rainer Schobert, Bernhard Biersack, Bianca Nitzsche

“…Background/Objectives: New drugs are required for the treatment of liver cancers and protozoal parasite infections. Analogs of the known anticancer active and antileishmanial 2′,4′,6′-trimethoxychalcone SU086 were prepared and investigated. …”
Get full text

RNA N4‐acetylcytidine modification and its role in health and diseases by Qiang Wang, Yixiao Yuan, Qiang Zhou, YingDong Jia, Jing Liu, GuangJun Xiao, Chunhong Li, Xiulin Jiang

“…Previous studies have demonstrated that ac4C plays a pivotal role in viral infections. Despite numerous studies highlighting the strong correlation between ac4C modification and cancer progression, its detailed roles and molecular mechanisms in normal physiological processes and cancer progression remain incompletely understood. …”
Get full text

Low-Dose Oxygen Enhances Macrophage-Derived Bacterial Clearance following Cigarette Smoke Exposure by William G. Bain, Ashutosh Tripathi, Pooja Mandke, Jonathan H. Gans, Franco R. D’Alessio, Venkataramana K. Sidhaye, Neil R. Aggarwal

“…Patients with COPD frequently suffer disease exacerbations induced by bacterial respiratory infections, suggestive of impaired innate immunity. …”
Get full text

Assessing waste separation behaviour in Nigeria: implications for post-Covid-19 pandemic waste management strategies by Tolulope B Olaiya, Shuliang Zhao, Oyewale D Abioye, Uzoamaka P Mgbachi, Oluwabunmi A Falebita

“…During medical emergencies, effective management of waste is crucial to preventing the spread of infections, protecting healthcare workers, and ensuring the safety of the broader society. …”
Get full text

Post-COVID pain and quality of life in COVID-19 patients: protocol for a meta-analysis and systematic review by Yongxing Xu, Jianwen Gu, Mengrong Miao, Yitian Yang, Pule Li, Mengqi Jia, Zhaoyu Wen, Mengmeng Yu, Jiaqiang Zhang

“…Introduction During the COVID-19 pandemic, approximately 10%–35% of COVID-19 infected patients experience post-COVID sequela. Among these sequelae, pain symptoms should not be neglected. …”
Get full text

Behavior of Olive Genotypes Against Quick Decline Syndrome (QDS) Caused by <i>Xylella fastidiosa</i> subsp. <i>pauca</i> in Apulia by Mariangela Carlucci, Michele Antonio Savoia, Pompea Gabriella Lucchese, Valentina Fanelli, Isabella Mascio, Francesco Luigi Aurelio, Monica Marilena Miazzi, Andrea Pacifico, Cinzia Montemurro, Franco Nigro

“…These genotypes, which survived in heavily infected areas, showed varied responses to <i>Xfp</i>; some maintained low symptom severity with minimal bacterial presence (high or undetectable Cq values), while others exhibited increased bacterial loads yet remained asymptomatic or showed limited canopy desiccation. …”
Get full text

Severe IgG4-Related Disease in a Young Child: A Diagnosis Challenge by Susana Corujeira, Catarina Ferraz, Teresa Nunes, Elsa Fonseca, Luísa Guedes Vaz

“…We report the case of a 22-month-old female child with failure to thrive and recurrent respiratory tract infections since 8 months of age. Physical examination was normal except for pulmonary auscultation with bilateral crackles and wheezes. …”
Get full text

Immune Activation, Immunosenescence, and Osteoprotegerin as Markers of Endothelial Dysfunction in Subclinical HIV-Associated Atherosclerosis by Alessandra D’Abramo, Maria Antonella Zingaropoli, Alessandra Oliva, Claudia D’Agostino, Samir Al Moghazi, Giulia De Luca, Marco Iannetta, Claudio Maria Mastroianni, Vincenzo Vullo

“…HIV-infected patients have a significantly greater risk of cardiovascular disease. …”
Get full text

Insight into the codon usage patterns and adaptation of Tembusu Virus by Fucheng Guo, Huiming Tan, Jinjin Yang, Rumin Jia, Ruichen Wang, Lie Wu, Fengzhi Pan, Kai Kang, Weitian Xie, Youquan Li, Kewei Fan

“…Thus, species-specific adaptability to the host environment may be a reason account for the distinct infectivity and clinic outcome of TMUV acted on hosts. …”
Get full text

Photocatalytic degradation of ciprofloxacin antibiotic from aqueous solution by BiFeO3 nanocomposites using response surface methodology by R. Mostafaloo, M. Asadi-Ghalhari, H. Izanloo, A. Zayadi

“…Ciprofloxacin antibiotic that is used to cure several kinds of bacterial infections have a high solubility capacity in water. …”
Get full text

Updates on hosts and distribution of pepper yellow leaf curl Indonesia virus and squash leaf curl China virus in Central Java Province, Indonesia by Adyatma Irawan Santosa, Adenisa Hanifah Irbati, Geby Nandita Cahyaning Pratiwi, Antama Surwadinata, Putri Laeshita, Krisnanda Surya Dharma, Reko Saputra Jaya, Annisa Lisa Andriyani, Chilya Qurrota A'yun, Chusnu Naura Syifa Fatika

“…However, PCR test confirmed only begomovirus infections. BLAST analysis concluded that the chili pepper and tomato isolates were pepper yellow leaf curl Indonesia virus (PepYLCIV) while the squash isolate was squash leaf curl China virus (SLCCNV). …”
Get full text

CRISPR/Cas9-Mediated Editing of a <i>NODULATION SIGNALING PATHWAY 1</i> Homolog Alters the Production of Strigolactones in Sunflower Roots by Maria A. Lebedeva, Maria S. Gancheva, Maksim R. Losev, Sofia V. Sokornova, Oleg S. Yuzikhin, Anna A. Krutikova, Kirill V. Plemyashov, Lyudmila A. Lutova

“…Sunflower (<i>Helianthus annuus</i> L.) is specifically infected by an obligatory root parasitic plant <i>Orobanche cumana Wallr.…”
Get full text

Proline isomerization modulates the bacterial IsdB/hemoglobin interaction: an atomic force spectroscopy study by Francesca Pancrazi, Omar De Bei, Francesco Lavecchia di Tocco, Marialaura Marchetti, Barbara Campanini, Salvatore Cannistraro, Stefano Bettati, Anna Rita Bizzarri

“…Our results suggest that these events might represent the molecular basis for the stress-dependence of bond strength observed for wild type IsdB, shedding light on the mechanisms that govern the capability of SA to infect host cells.…”
Get full text

Prevalence of TB-related symptoms and self-reported disability among adult TB survivors by A.K. McDonald, D. Nakkonde, P. Kaggwa, S. Zalwango, A. Joseph, E. Buregyeya, J.N. Sekandi

“…RESULTS: Of the 200 participants, the median age was 33.0 years (IQR 26–44.5); 52.5% were male, and 23% were HIV-infected. The prevalence of TB symptoms was 58%, and self-reported disability was 83.5%. …”
Get full text

Fungal Biocontrol Agents in the Management of Postharvest Losses of Fresh Produce—A Comprehensive Review by Phathutshedzo Ramudingana, Ndivhuho Makhado, Casper Nyaradzai Kamutando, Mapitsi Silvester Thantsha, Tshifhiwa Paris Mamphogoro

“…Physical methods, on the other hand, cause damage to fresh produce, exposing it to even more infections. Therefore, healthier and more environmentally friendly alternatives to existing methods for managing postharvest decays of fresh produce should be advocated. …”
Get full text

Prevalence of Undernutrition and Its Associated Factors among Children below Five Years of Age in Bure Town, West Gojjam Zone, Amhara National Regional State, Northwest Ethiopia by Desalegne Amare, Ayenew Negesse, Baye Tsegaye, Birtukan Assefa, Birehanu Ayenie

“…Male sex, maternal educational status, low household income, preterm babies, absence of antenatal follow-up, diarrhea, and respiratory infections within one-month duration were factors affecting undernutrition.…”
Get full text

Acute Kidney Injury Caused by Obstructive Nephropathy by Jonathan S Chávez-Iñiguez, Goretty J Navarro-Gallardo, Ramón Medina-González, Luz Alcantar-Vallin, Guillermo García-García

“…The diagnosis consists of a complete medical history and should include changes in urinary voiding and urgency and enuresis, history of urinary tract infections, hematuria, renal lithiasis, prior urinary interventions, and constipation. …”
Get full text