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11601
Mathematical Modelling of Cholera Transmission incorporating Media Coverage.
Published 2024“…The spread of the disease depends largely on social and environmental factors such as, eating food or drinking water contaminated with feaces from an infected person. Cholera outbreaks, for instance, in Uganda have led to deaths and hospitalization. …”
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11602
The Role of Community-Based Organisations in Compating HIV/AIDS in Kanungu District, Uganda.
Published 2020“…Kanungu Development Initiative has proved that CBOs have great potential in not only educating people about the prevention of HIV/AIDS, but also in providing care and support to people living with HIV/AIDS and their families, by providing a wide range of interventions to both the people infected and affected by the pandemic. The study recommended that there was a need to establish or strengthen partnerships other service providers outside the field of HIV/AIDS to complement services provided by KADI, for example linking clients to organisations providing income generating activities like operations wealth creation, prosperity for all program, to mention but a few.…”
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11603
Comprehensive epidemiological evaluation of ruminant brucellosis and associated risk factors in some Egyptian Governorates
Published 2025-12-01“…The difficulty in accurately diagnosing all infected animals, particularly carriers, is a major limitation of eradication and control programs. …”
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11604
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11605
Understanding Nigeria’s antibiotic resistance crisis among neonates and its future implications
Published 2025-01-01“…Studies show a significant rise in multi-drug-resistant infections, with almost half of Escherichia coli and 86% of Staphylococcus aureus strains among newborns resistant to conventionally used antibiotics like penicillin. …”
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11606
From Isolation to Application: Utilising Phage‐Antibiotic Synergy in Murine Bacteremia Model to Combat Multidrug‐Resistant Enterococcus faecalis
Published 2025-01-01“…ABSTRACT Enterococcus species, natural inhabitants of the human gut, have become major causes of life‐threatening bloodstream infections (BSIs) and the third most frequent cause of hospital‐acquired bacteremia. …”
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11607
The Prevalence of Enteric Viruses in Bivalve Molluscs in a Farming Area in Liguria, Northwest Italy
Published 2024-12-01“…Although norovirus (NoV) and the hepatitis A virus (HAV) are considered the most common causes of foodborne infections, in recent years, other viruses with a zoonotic potential have been identified in shellfish, such as the hepatitis E virus (HEV), astrovirus (AsV), and aichi virus (AiV). …”
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11608
Prevalence, Molecular Epidemiology, and Clinical Characteristics of Human Bocavirus Among Patients with Acute Gastroenteritis in Northern Brazil During 2017–2022
Published 2025-01-01“…Genotypes HBoV-1, HBoV-2, HBoV-3, and HBoV-4 were found in 42.5% (17/40), 22.5% (9/40), 32.5% (13/40), and 2.5% (1/40) of the specimens, respectively. Co-infections with HBoV and other enteric viruses occurred in 48.3% (31/64) of cases, with RVA being the most frequent (31.2%, 20/64). …”
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11609
Water Birth – Benefits, Risks, and Controversies
Published 2025-01-01“…Water birth, however, carries potential risks, such as neonatal respiratory complications and infections, although studies generally report no significant differences in neonatal outcomes compared to land birth. …”
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11610
Population Structure Based on Microsatellite Length Polymorphism, Antifungal Susceptibility Profile, and Enzymatic Activity of <i>Candida auris</i> Clinical Isolates in Russia
Published 2025-01-01“…<i>Candida auris</i> is an emerging multidrug-resistant fungal pathogen causing nosocomial transmission and invasive infections with high mortality. This study aimed to investigate the genetic relationships, enzymatic activities, and drug-resistance profiles of <i>C. auris</i> isolates to evaluate the population and epidemiological diversity of candidiasis in Russia. …”
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11611
A mechanistic overview on green assisted formulation of nanocomposites and their multifunctional role in biomedical applications
Published 2025-02-01“…Incorporating phytosynthesized nanocomposites in therapeutic interventions not only enhances healing processes but also augments the host's immune defenses against infections. This review highlights the phytosynthesis of nanocomposites and their various biomedical applications, including antibacterial, antidiabetic, antiviral, antioxidant, antifungal, anti-cancer, and other applications, as well as their toxicity. …”
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11612
<i>In Vitro</i> and <i>In Vivo</i> Evaluation of the Antischistosomal Activity of Polygodial and 9-Deoxymuzigadial Isolated from <i>Drimys brasiliensis</i> Branches
Published 2025-01-01“…Finally, in vivo studies with <i>S. mansoni</i>-infected mice treated with compound <b>1</b> demonstrated a 44.0% reduction in worm burden, accompanied by decreases in egg production of 71.8% in feces and 69.5% in intestines. …”
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11613
Correlation between Intraoperative Fluid Administration and Outcomes of Pancreatoduodenectomy
Published 2020-01-01“…The in-hospital mortality rate was 7.28% with the most common cause being grade C POPF and secondary intra-abdominal infections. The patients in the liberal group had significantly higher incidences of POPF (25%) and respiratory complications (21.43%). …”
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11614
The Global Challenge of <i>Campylobacter</i>: Antimicrobial Resistance and Emerging Intervention Strategies
Published 2025-01-01“…Resistance to fluoroquinolones, macrolides, and tetracyclines complicates treatment and increases the risk of severe infections. Drug-resistant <i>Campylobacter</i> is transmitted to humans via contaminated food, water, and direct contact with animals, highlighting its zoonotic potential. …”
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11615
Pharmacophore-based approach for the identification of prospective UDP-2,3-diacylglucosamine hydrolase (LpxH) inhibitor from natural product database against Salmonella Typhi
Published 2025-06-01“…The study concluded that compounds 1615 and 1553 hold significant potential as lead molecules for developing new treatments against drug-resistant S. Typhi infections. This study illustrates how computational techniques, such as MD simulations and pharmacophore modeling, can speed up drug discovery, especially in the fight against antibiotic resistance.…”
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11616
Detection and Whole-Genome Characteristics of <i>Bordetella trematum</i> Isolated from Captive Snakes
Published 2025-01-01“…<i>Bordetella trematum</i> is a rare member of the genus <i>Bordetella</i>, primarily associated with human wound infections rather than respiratory diseases. The bacterium has been isolated from various clinical specimens, including ear inflammatory discharge, diabetic ulcers, and chronic wounds. …”
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11617
Machine learning and genetic algorithm-guided directed evolution for the development of antimicrobial peptides
Published 2025-02-01“…Introduction: Antimicrobial peptides (AMPs) are valuable alternatives to traditional antibiotics, possess a variety of potent biological activities and exhibit immunomodulatory effects that alleviate difficult-to-treat infections. Clarifying the structure-activity relationships of AMPs can direct the synthesis of desirable peptide therapeutics. …”
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11618
Penetration of linezolid and tedizolid in cerebrospinal fluid of mouse and impact of blood–brain barrier disruption
Published 2025-01-01“…Abstract Penetration of antimicrobial treatments into the cerebrospinal fluid is essential to successfully treat infections of the central nervous system. This penetration is hindered by different barriers, including the blood–brain barrier, which is the most impermeable. …”
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11619
Comparative in Vitro Study on the Antimicrobial Efficacy of Endodontic Sealers Against Common Oral Pathogens
Published 2024-12-01“…<b>Background/Objectives</b>: Microorganisms are the leading cause of infections in the root canal system, contributing to the failure of endodontic treatments. …”
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11620
Spireoside Controls Blast Disease by Disrupting Membrane Integrity of Magnaporthe oryzae
Published 2025-01-01“…We found that 24 and 48 h post-inoculation with Magnaporthe oryzae were critical time points for metabolomic profiling, based on the infected status of M. oryzae in rice and the observed differences in shikimate accumulation between the two varieties. …”
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