Involvement of the TGF-β pathway in epithelialmesenchymal transition promoted by the pulmonary microenvironment in Mycoplasma pneumoniae pneumonia by Fan Lu, Wang Huixia, Xu Nuo, Guo Yun, Li Ling

“…Mycoplasma pneumoniae (MP), one of the smallest prokaryotic microorganisms capable of independent survival, causes respiratory tract infections and various extrapulmonary diseases. Mycoplasma pneumoniae pneumonia (MPP) is the most significant clinical manifestation, often leading to complications such as atelectasis and pulmonary fibrosis. …”
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Relationship between Indicators of Nutritional Status and the Development of Pneumonia Associated with Ischemic Stroke by Alexis Suárez Quesada, Alexis Álvarez Aliaga, Julia Matilde Pupo Jiménez, Joel Berdú Saumell, Marta Elena Hernández Galano

“…This disease causes severe consequences in the clinical course, increases the risk of infections, among which pneumonia highlight, mortality and hospital stay. …”
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PCR-based methodologies for detection and characterization of Listeria monocytogenes and Listeria ivanovii in foods and environmental sources by Jin-Qiang Chen, Stephanie Healey, Patrick Regan, Pongpan Laksanalamai, Zonglin Hu

“…Specifically, we described (a) conventional PCR and mono-, duplex- and multiplex-qPCR methodologies; (b) development and applications of gene HlyA-, Iap-, PrfA – and SsrA-based conventional and qPCR assays as well as PCR assays targeting newly identified gene targets for specific detection of L. monocytogenes; differentiation of viable from dead L. monocytogenes by qPCR in conjugation with propidium monoazide pretreatment; PCR-based serotype identification of L. monocytogenes isolates; PCR-based detection of L. ivanovii, infecting ruminants, differentiation of L. monocytogenes from other Listeria species; and sigB-gene based PCR identification of Listeria spp; (c) applications of ddPCR in detection of L. monocytogenes; and (d) application of qPCR assays in detection and subtyping of L. monocytogenes in milk and dairy products; meats, meat products and meat-processing environment; and seafood, seafood products and processing environment. …”
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Assessing environmental and human health risks of pharmaceutical contamination in surface water by Ioana-Antonia Cimpean, Florentina Laura Chiriac, Diana Constantinescu-Groposila, Victor Constantin Cojocaru, Vasile Ion Iancu

“…Pharmaceuticals, also known as medicines, are a mixture of substances used to prevent and treat human or animal diseases or infections. These products are used in many areas, such as medicine, aquaculture, animal husbandry, and, not least, in people’s everyday lives. …”
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Deciphering the significance of neutrophil to lymphocyte and monocyte to lymphocyte ratios in tuberculosis: A case-control study from southern India [version 2; peer review: 2 appr... by Poorva Bakshi, Shikha Jayasheelan, Rakshatha Nayak, Sharada Rai

“…While AFB culture remains a gold standard for diagnosing TB and other mycobacterial infections, its limitations include slow turnaround time, and the requirement for specialized resources and expertise. …”
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Harnessing natural polymers and nanoparticles: Synergistic scaffold design for improved wound healing by Anitha S, Nandini Robin Nadar, Srividya Shivakumar, Sharma S C, Siddharth P, Surekha Varalakshmi V, Rajesh Lenka, Rajadurai S

“…Skin injuries may be due to acute or chronic trauma, infections, and operations and can cause severe dysfunction or death. …”
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Multiplex Evaluation of Influenza Neutralizing Antibodies with Potential Applicability to In-Field Serological Studies by Eleonora Molesti, Edward Wright, Calogero Terregino, Rafat Rahman, Giovanni Cattoli, Nigel J. Temperton

“…Sera obtained from chickens vaccinated with a monovalent H5N2 vaccine, chickens vaccinated with a bivalent H7N1/H5N9 vaccine, or turkeys naturally infected with an H7N3 virus were evaluated in this assay and the results correlated strongly with data obtained by HI assay. …”
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Antimalarial Efficacy and Antioxidant Activity of Lophira lanceolata Stem Bark Ethanol Extract Using Plasmodium berghei Induced-Malaria in Swiss Albino’s Mice by Mounvera Abdel Azizi, Noumedem Anangmo Christelle Nadia, Yamssi Cedric, Ngouyamsa Nsapkain Aboubakar Sidiki, Gamago Nkadeu Guy-Armand, Djeussi Doriane Esther, Tientcheu Noutong Jemimah Sandra, Tako Djimefo Alex Kevin, Vincent Khan Payne

“…The antimalarial activity was determined using the Peter 4-days’ suppressive and Rane’s curative tests on Swiss albino: these mice were infected with 1×107 parasitized red blood cells. The percentage reduction of parasitemia was related to each test, and the liver homogenate was used to assay malondialdehyde, superoxide dismutase, nitrogen monoxide, catalase, and glutathione for the evaluation of oxidative stress. …”
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Pulmonary Bacterial Communities in Surgically Resected Noncystic Fibrosis Bronchiectasis Lungs Are Similar to Those in Cystic Fibrosis by Heather Maughan, Kristopher S. Cunningham, Pauline W. Wang, Yu Zhang, Marcelo Cypel, Cecilia Chaparro, D. Elizabeth Tullis, Thomas K. Waddell, Shaf Keshavjee, Mingyao Liu, David S. Guttman, David M. Hwang

“…Recurrent bacterial infections play a key role in the pathogenesis of bronchiectasis, but conventional microbiologic methods may fail to identify pathogens in many cases. …”
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Aberrant heterochromatin silences immune response genes in chronic lymphocytic leukemia by Olivia M. Depies, Qianqian Guo, Yuan Gao, Sutapa Sinha, Zhenqing Ye, Weiguo Han, Kari G. Rabe, Mingma S. Hoel, Heather C. Darby, Chuanhe Yu, Esteban Braggio, Sameer A. Parikh, Susan L. Slager, Neil E. Kay, Zhiquan Wang

“…In summary, we described an epigenetic silencing mechanism mediated by the heterochromatin that persists throughout CLL disease development and treatment and which may increase the risk of severe infections in MBL and CLL.…”
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Expression of Toll-Like Receptors 2 and 4 and Related Cytokines in Patients with Hepatic Cystic and Alveolar Echinococcosis by Tuerhongjiang Tuxun, Hai-Zhang Ma, Shadike Apaer, Heng Zhang, Amina Aierken, Yu-Peng Li, Ren-Yong Lin, Jin-Ming Zhao, Jin-Hui Zhang, Hao Wen

“…Several studies have demonstrated the important role of Toll-like receptors in various parasitic infections. This study aims to explore expression of Toll-like receptors (TLRs) and related cytokines in patients with human cystic echinococcosis (CE) and alveolar echinococcosis (AE). 78 subjects including AE group (N=28), CE group (N=22), and healthy controls (HC, N=28) were enrolled in this study. …”
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Nutrition before and during Surgery and the Inflammatory Response of the Heart: A Randomized Controlled Trial by Marlieke Visser, Hans W. M. Niessen, Wouter E. M. Kok, Riccardo Cocchieri, Willem Wisselink, Paul A. M. van Leeuwen, Bas A. J. M. de Mol

“…Major surgery induces a long fasting time and provokes an inflammatory response which increases the risk of infections. Nutrition given before and during surgery can avoid fasting and has been shown to increase the arginine/asymmetric dimetlhylarginine ratio, a marker of nitric oxide availability, in cardiac tissue and increased concentrations of branched chain amino acids in blood plasma. …”
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The Antibacterial Effect of Tinospora Cordifolia (Guduchi) and Its Role in Combating Antimicrobial Resistance by Kavitha EZHILARASU, Anand KASIRANJAN, Shanmuga PRIYA, Anand KAMARAJ

“…In order to combat the MDR infections isolated from patients' bodies, the current study was conducted to evaluate and investigate the antibacterial capabilities of Tinospora cordifolia. …”
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SARS-CoV-2 Remained Airborne for a Prolonged Time in a Lockdown Confined Space by Xinyue Li, Xiao Qi, Jianxin Ma, Yang Pan, Tian Tian, Yue Zhang, Zhen Li, Wenjing Li, Lingli Sun, Lu Zhang, Zheng Zhang, Quanyi Wang, Maosheng Yao

“…Here, we investigated a COVID-19 outbreak with two fast food employees infected, in which a traveler despite of a 14-day quarantine turned positive after check in with a hotel, using environmental SARS-CoV-2 sampling, epidemiological tracing, viral RNA sequence as well as surveillance method. …”
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A Rare Case of Pneumonia Caused by Shewanella putrefaciens by Rajshree Patel, Albin Abraham, Johnson Thomas, Wanqing Zhi, Shadab Ahmed, Janice Verley

“…It can produce a wide variety of clinical syndromes including bacteremia as well as skin and soft tissue infections. However, pneumonia due to S. putrefaciens is rare; there are a total of 4 reported cases in the literature. …”
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A Multiagent Alphavirus DNA Vaccine Delivered by Intramuscular Electroporation Elicits Robust and Durable Virus-Specific Immune Responses in Mice and Rabbits and Completely Protect... by Lesley C. Dupuy, Michelle J. Richards, Brian D. Livingston, Drew Hannaman, Connie S. Schmaljohn

“…Taken together, the results from these studies demonstrate that the individual VEEV, WEEV, and EEEV DNA vaccines and the 3-EEV DNA vaccine delivered by IM EP provide an effective means of eliciting protection against lethal encephalitic alphavirus infections in a murine model and represent viable next-generation vaccine candidates that warrant further development.…”
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A combined recombinase polymerase amplification CRISPR/Cas12a assay for detection of Fusarium oxysporum f. sp. cubense tropical race 4 by Megan Ceris Matthews, Jos van der Linden, Isabelle Robène, Samuel Rozsasi, Beatrix Coetzee, Manuela Campa, Johan Burger, Uzoma Nobel Akwuruoha, Ndubuisi Johnkennedy Madufor, Willem Perold, Umezuruike Linus Opara, Altus Viljoen, Diane Mostert

“…The RPA-Cas12a assay detected Foc TR4 from naturally infected banana samples collected in the field and visualization was possible with the naked eye under LED blue light transillumination. …”
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Partly cloudy with a chance of mosquitoes: Developing a flexible approach to forecasting mosquito populations by Travis McDevitt‐Galles, Arthur T. Degaetano, Sarah C. Elmendorf, John R. Foster, Howard S. Ginsberg, Mevin B. Hooten, Shannon LaDeau, Katherine M. McClure, Sara Paull, Erin Posthumus, Ilia Rochlin, Daniel Grear

“…The timing and intensity of mosquito interactions with infected and susceptible hosts are a primary determinant of vector‐borne disease dynamics. …”
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Using a Herd Profile to Determine Age-Specific Prevalence of Bovine Leukemia Virus in Michigan Dairy Herds by Ronald J. Erskine, Paul C. Bartlett, Todd M. Byrem, Chelsea L. Render, Catherine Febvay, Jessica T. Houseman

“…The mean BHP for all herds was 32.8%, with means of 18.5, 28.8, 39.2, and 44.8% of 1st, 2nd, 3rd, and ≥4th lactation animals infected, respectively. In eight herds, we determined the correlation between the BHP, and true herd prevalence by testing the entire lactating herd (r=0.988,  P<0.0001). …”
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Innovations in Nipple-areolar Complex Reconstruction: Evaluation of a New Prosthesis by Michele Riccio, MD, Angelica Aquinati, MD, Mario Fordellone, PhD, Nicola Carboni, MD, Andrea Marchesini, MD, Francesco De Francesco, MD, PhD

“…Except for 4 patients, there were no reports of skin adverse reactions, infections, or erosion. Conclusions:. Encouraged by these auspicious outcomes that indicate a significant rate of safety and satisfaction, we believe that this straightforward, noninvasive, affordable medical device deserves consideration as a reconstructive option for all patients seeking breast reconstruction, promoting full body integrity.…”
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