Regulated microbe vaccines: from concept to (pre-clinical) reduction to practice by Richard Voellmy, David C Bloom, Nuria Vilaboa

“…Introduction Vaccines to prevent important infections involving, e.g. influenza viruses, severe acute respiratory syndrome-causing coronaviruses (e.g. …”
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Expert Opinion on Fixed Dose Combination of Dapagliflozin Plus Sitagliptin for Unmet Cardiovascular Benefits in Type 2 Diabetes Mellitus by Soumitra Ray, J Ezhilan, Rajiv Karnik, Ashish Prasad, Rajashree Dhar

“…The fixed dose combination (FDC) of sodium-glucose cotransporter-2 (SGLT2) inhibitors and dipeptidyl peptidase-4 (DPP-4) inhibitors provides both glycemic and pleiotropic effects, including lower risk of hypoglycemia, lower rates of genitourinary tract infections, and weight neutrality. Based on CV risk, including HF, the combination of SGLT2i and DPP4i may be preferred over other conventional therapies (those with no CV benefit) in cases of established CV disease and/or HF risk. …”
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Limited Transmission of the Ectoparasitic Fungus Hesperomyces virescens between Lady Beetles by Ted E. Cottrell, Eric W. Riddick

“…The ectoparasitic fungus Hesperomyces virescens Thaxter (Ascomycota: Laboulbeniales) commonly infects the invasive lady beetle Harmonia axyridis (Pallas) and several other aphidophagous lady beetles in North America and Europe. …”
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Nonlinear Pulse Vaccination in an SIR Epidemic Model with Resource Limitation by Wenjie Qin, Sanyi Tang, Robert A. Cheke

“…Once the threshold value exceeds a critical level, both susceptible and infected populations can oscillate periodically. Furthermore, when the pulse vaccination period is chosen as a bifurcation parameter, the SIR model with nonlinear pulse vaccination reveals complex dynamics including period doubling, chaotic solutions, and coexistence of multiple attractors. …”
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First report of wilt disease in cashew (Anacardium occidentale L.) caused by Fusarium decemcellulare in Kerala, India by A. V. Meera Manjusha, P. K. Laya, Amal Premachandran, M. Veena

“…Methods A fungal pathogen was isolated repeatedly from the infected vascular tissues onto potato dextrose agar medium. …”
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A Semi-supervised Deep Learning Method for Cervical Cell Classification by Siqi Zhao, Yongjun He, Jian Qin, Zixuan Wang

“…It can detect precancerous conditions and microbial infections. However, this technique entirely relies on manual operation and doctors’ naked eye observation, resulting in a heavy workload and low accuracy rate. …”
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Treatment outcomes in NTM-PD in a high TB burden context by S. Kang, J.E. Schmidt, I. Chen, S. Tiberi

“…The addition of cefoxitin and linezolid improved culture conversion rates in MC-AG-infected patients. One study ( n = 24) demonstrated that resecting lesions and chemotherapy led to more favourable clinical outcomes. …”
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Propionibacterium acnes: A Treatable Cause of Constrictive Pericarditis by Daniel Cruz, Haitham Ahmed, Yousuf Gandapur, M. Roselle Abraham

“…In this case report we share a case of infective Pericarditis caused by Propionibacterium acnes (P. acnes) in an immune-competent, nonsurgical patient. …”
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Unleashing the Power of Artificial Intelligence-Driven Drug Discovery in Streptomyces by Wei-Shan Ang, Jodi Woan-Fei Law, Yatinesh Kumari, Vengadesh Letchumanan, Loh Teng-Hern Tan

“…., paved the way for discovering other antibiotics for combating bacterial infections. By exploring the genome-based biosynthetic potential of various Streptomyces species, a vast array of secondary metabolites with potential therapeutic applications can be identified, contributing a transformative impact on the field of medicine. …”
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Serum IL-18 Is Increased at Early Postburn Period in Moderately Burned Patients by Y. Kenan Coban, Murat Aral

“…IL-18 enhances the Th1 immune responses in bacterial andviral infections. In order to evaluate the IL-18 serum levels as well as IL-6 and TNF-α at the 48th hour postburn, serial serum samples of 8 burned patients were analyzed. 8 moderately burned patients were included into the study. …”
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Theories, models and strategies in developing an effective HIV/AIDS campaign in South Africa by Mpine Qakisa

“…The purpose of HIV/AIDS health communication and campaigns is to educate by improving health, reducing the risks of HIV infections and promoting the well-being of individuals and communities. …”
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Factors Associated with Methicillin Resistant Staphylococcus aureus Carriage by Masood Abdulkareem Abdulrahman, Arazoo Issa Taher

“…Methicillin Resistant Staphylococcus Aureus carrier rate showed a significant association with skin and soft tissue infections, health facilities visits and certain jobs of food handlers. …”
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Predictors associated with time to default for HIV/AIDS patients under HAART at Debre Tabor Referral Hospital: a Cox regression model by Koyachew Bitew Abebe

“…To advance the longevity of HIV/AIDS-infected patients within HAART medication, an intervention should be taken from the concerned body for those patients who had been at high risk of defaulting during initial and some stages of treatment. …”
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Psychological Determinants and Consequences of COVID-19 Anxiety: A Web-Based Study in Iran by Reza Shabahang, Mara S. Aruguete, Sajjad Rezaei, Lynn E. McCutcheon

“…The participants also responded to two additional questions: "Do you personally know of anyone who was suspected of having been infected with COVID-19?" and "Did you get sick in the past year?” …”
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The Detection of Fosfomycin-Modifying Enzymes (fos) in Uropathogenic Enterobacterale, Azerbaijan, Iran by Aidin Lalezadeh, Pardis Ghotaslou, Reza Ghotaslou

“…Enterobacteriaceae is the most common agent of urinary tract infections (UTIs). Multidrug resistant (MDR) and XDR (extensively drug-resistant) Enterobacteriaceae in UTIs have increased in the world. …”
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Interventions impacting the accessibility of sexual reproductive health services for head porters in sub-Saharan Africa- A scoping review protocol. by Kimberly Jarvis, Solina Richter, Samuel Adjorlolo, Michelle Swab, Eric Tenkorang, Yuping Mao, Laura A Chubb, Charles Ampong Adjei, William Midodzi, Adom Manu, Kwasi Torpey, Cara Spence, Pammla Petrucka

“…Most female head porters are in their reproductive years and often lack access to sexual reproductive health services (SRHS) despite being at high risk for sexually transmitted infections (STIs), unplanned pregnancies, and gender-based violence. …”
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Th2 Regulation of Viral Myocarditis in Mice: Different Roles for TLR3 versus TRIF in Progression to Chronic Disease by Eric D. Abston, Michael J. Coronado, Adriana Bucek, Djahida Bedja, Jaewook Shin, Joseph B. Kim, Eunyong Kim, Kathleen L. Gabrielson, Dimitrios Georgakopoulos, Wayne Mitzner, DeLisa Fairweather

“…Viral infections are able to induce autoimmune inflammation in the heart. …”
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Challenges and Economic Implications in the Control of Foot and Mouth Disease in Sub-Saharan Africa: Lessons from the Zambian Experience by Y. Sinkala, M. Simuunza, D. U. Pfeiffer, H. M. Munang’andu, M. Mulumba, C. J. Kasanga, J. B. Muma, A. S. Mweene

“…Foot and mouth disease is one of the world’s most important livestock diseases for trade. FMD infections are complex in nature and there are many epidemiological factors needing clarification. …”
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Mechanisms of T-cell Depletion in Tumors and Advances in Clinical Research by Xiangfei Su, Mi Zhang, Hong Zhu, Jingwen Cai, Zhen Wang, Yuewei Xu, Li Wang, Chen Shen, Ming Cai

“…Abstract T lymphocytes (T cells) are essential components of the adaptive immune system that play a vital role in identifying and eliminating infected and tumor cells. In tumor immunotherapy, T cells have emerged as a promising therapeutic strategy due to their high specificity, potent cytotoxic capability, long-lasting immune memory, and adaptability within immunotherapeutic approaches. …”
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Successful Treatment of Fungal Dermatitis in a Bottlenose Dolphin (<i>Tursiops truncatus</i>) by Takashi Kamio, Honoka Nojo, Rui Kano, Mami Murakami, Yukako Odani, Koji Kanda, Tomoko Mori, Yuichiro Akune, Masanori Kurita, Ayaka Okada, Yasuo Inoshima

“…Immunosuppression by chronic diseases and starvation decreased resistance against opportunistic infections. Sequencing analysis revealed that the fungi on the wound surface were <i>Fusarium oxysporum,</i> and antifungal susceptibility testing was performed. …”
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