Pitfalls in Diagnosis: JMML versus KMT2A Rearranged Juvenile AML by Liesbeth Vanheeswijck, Sanjay Tewari, Robin Dowse, Nicola Potter, Jelena Jovanovic, Caroline L. Furness, Elsje Van Rijswijk

“…We report a case of a 20-month-old girl, who presented with lethargy, recurrent infections, bruising, and marked hepatosplenomegaly. …”
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Design, synthesis and molecular docking of novel triazole derivatives as potential CoV helicase inhibitors by Zaher Nashwa Hafez, Mostafa Mohammed Ismail, Altaher Abdullah Yousef

“…Middle East respiratory syndrome coronavirus (MERS-CoV) had emerged and spread because of the worldwide travel and inefficient healthcare provided for the infected patients in several countries. Herein we investigated the anti-MERS-CoV activity of newly synthesized sixteen halogenated triazole compounds through the inhibition of helicase activity using the FRET assay. …”
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Marine Diterpenoids as Potential Anti-Inflammatory Agents by Yisett González, Daniel Torres-Mendoza, Gillian E. Jones, Patricia L. Fernandez

“…The search for agents inhibiting inflammation is a great challenge as the inflammatory response plays an important role in the defense of the host to infections. Marine invertebrates are exceptional sources of new natural products, and among those diterpenoids secondary metabolites exhibit notable anti-inflammatory properties. …”
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Ciprofloxacin stress changes key enzymes and intracellular metabolites of Lactobacillus plantarum DNZ-4 by Pin Chen, Xiaoqian Chen, Wei Yu, Bo Zhou, Lihua Liu, Yuzhuo Yang, Peng Du, Libo Liu, Chun Li

“…Ciprofloxacin (CIP) is an antibiotic used to treat infections caused by bacteria. In this experiment, key enzymes and intracellular metabolites of Lactobacillus plantarum DNZ-4 was researched under CIP stress. …”
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The Emergence of Extensively Drug-Resistant Tuberculosis (TB): TB/HIV Coinfection, Multidrug-Resistant TB and the Resulting Public Health Threat from Extensively Drug-Resistant TB,... by Paul E Alexander, Prithwish De

“…There is evidence that persons infected with HIV are more likely to experience XDR-TB. …”
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Pyogenic Sacroiliitis in Children: Two Case Reports by L. Ghedira Besbes, S. Haddad, A. Abid, Ch. Ben Meriem, M. N. Gueddiche

“…Pyogenic sacroiliitis is rare and accounts for approximately 1-2% of osteoarticular infections in children. Considerable delay between presentation and diagnosis is recognized. …”
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Parameter estimation and uncertainty quantification for an epidemic model by Alex Capaldi, Samuel Behrend, Benjamin Berman, Jason Smith, Justin Wright, Alun L. Lloyd

“…We examine estimation of the parameters of Susceptible-Infective-Recovered(SIR) models in the context of least squares. …”
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Lipid Antigens: Revealing the Hidden Players in Adaptive Immune Responses by Tamana Eskandari, Yasamin Eivazzadeh, Fatemeh Khaleghinia, Fatemeh Kashi, Valentyn Oksenych, Dariush Haghmorad

“…Lipid trafficking, CD1 molecule interactions, and the immune system’s response to lipid antigens are yet to be completely understood, particularly in the context of autoimmunity and microbial infections. In the years to come, continued research efforts are needed to uncover its underlying biological mechanisms and to exploit the full potential of therapies directed against lipid antigens.…”
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Emerging nanomedicine strategies for hepatocellular carcinoma therapy by Chen Guo, Jiayu Zhang, Xiaomeng Cai, Rui Dou, Jiaruo Tang, Zhengyuan Huang, Xueting Wang, Yan Guo, Hanqing Chen, Jun Chen

“…Abstract Hepatocellular carcinoma (HCC) is a prevalent malignant tumor with a range of risk factors, including viral infections, alcoholic liver disease, exposure to fungal toxins, obesity, and type 2 diabetes. …”
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Biochemical Composition of Propolis and Its Efficacy in Maintaining Postharvest Storability of Fresh Fruits and Vegetables by İbrahim Kahramanoğlu, Volkan Okatan, Chunpeng Wan

“…Moreover, it has a long history in the traditional and scientific medicine as having antibacterial, anticancer, anti-inflammatory, anti-infective, and wound healing effects since 300 BC. …”
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Secondary Syphilis Presenting as Glossodynia, Plaques en Prairie Fauchée, and a Split Papule at the Oral Commissure: Case Report and Review by Walter de Araujo Eyer-Silva, Maria Alessandra Leite Freire, Cecília Angelina Horta-Araujo, Guilherme Almeida Rosa da Silva, Jorge Francisco da Cunha Pinto, Fernando Raphael de Almeida Ferry

“…We report the case of a 45-year-old HIV-infected male patient in whom secondary syphilis presented with burning mouth and dysgeusia that progressed to glossodynia and odynophagia. …”
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A systematised review and evidence synthesis on the broader societal impact of vaccines against Salmonella by Ezgi Dilek Demirtas, Rosanna Barnard, Jungseok Lee, Mark Jit

“…Despite variations in study design, methodology, and study quality, salmonellae infections were largely associated with negative broader societal impacts, including detriments in childhood physical development (very weak association), childhood educational development (strong to very strong association), household security (moderate association), public health spending (moderate association), and national income (moderate to strong association). …”
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Development of an in vitro triculture model of intestine inflammation to assess the immunomodulatory properties of cassava and roselle, two African green leafy vegetables by Nelly Fioroni, Maria Del Carmen Ponce de León Rodríguez, Nicolas Leconte, Claire Mouquet-Rivier, Caroline Guzman, Frédéric Boudard, Claudie Dhuique-Mayer, Myriam Collin, Anaïs Deglos, Emmanuelle Reboul, Ángela Bravo-Núñez, Caroline Laurent-Babot

“…In sub-Saharan Africa, frequent infections and enteric dysfunction can cause intestinal inflammation that is associated with stunting. …”
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Growth and Neurodevelopmental Outcome in Preterm LBW Infants with Sepsis in India: A Prospective Cohort by Sunil J. Pawar, Tejopratap Oleti, Siluvery Bharathi, Shyamsunder Tipparaju, Ershad Mustafa

“…Conclusion. Neonatal infections are associated with the abnormal neurodevelopmental outcomes in LBW infants but there was no significant difference at growth outcome at 9 to 15 months of corrected age between both groups.…”
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Association between Severe Dehydration in Rotavirus Diarrhea and Exclusive Breastfeeding among Infants at Dr. Hasan Sadikin General Hospital, Bandung, Indonesia by Dwi Prasetyo, Iesje Martiza Sabaroedin, Yudith Setiati Ermaya, Yati Soenarto

“…Infants who are exclusively breastfed develop fewer infections and have less severe illnesses. This study aimed to determine association between severe dehydration in rotavirus diarrhea and exclusive breastfeeding. …”
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Potential use of peptides mimicking CRAC/CARC domains as antivirulence therapies to inhibit RTX toxins activities by Vanesa Herlax

“…In recent years, research efforts have increased to develop new therapeutics aimed at combating antibiotic-resistant bacterial infections. These efforts focus on inhibiting the virulence factors bacteria secrete to proliferate. …”
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IL-18 biology in severe asthma by Sarita Thawanaphong, Sarita Thawanaphong, Sarita Thawanaphong, Aswathi Nair, Aswathi Nair, Emily Volfson, Emily Volfson, Parameswaran Nair, Parameswaran Nair, Manali Mukherjee, Manali Mukherjee

“…Furthermore, we discuss the emerging evidence of IL-18’s involvement in autoimmunity and highlight potential therapeutic targets within the IL-18 and inflammasome pathways in severe asthma patients with evidence of infections and airway autoimmune responses. By synthesizing recent advancements and ongoing research, this review underscores the importance of IL-18 as a potential novel therapeutic target in the treatment of severe asthma and other related conditions.…”
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Aspergillus fumigatus ctf1–a novel zinc finger transcription factor involved in azole resistance by Xiao Gong, Heng Zhang, Wenxu Cheng, Zhangxuan He, Tianyan Ma, Tian Chen, Yi Sun

“…Elucidating the mechanisms underlying antifungal resistance in Aspergillus fumigatus, discovering new antifungal targets, and developing drugs to inhibit resistance are the key approaches to treating A. fumigatus infections. Here, we investigated the function of ctf1 (AFUA_1G03800), a gene encoding a C6 transcription factor. …”
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Determination of whole genome sequence of human cytomegalovirus circulating in Japan and discovery of geographic genome structure in UL148 gene by Yuji Wada, Ken Ishioka, Tatsuo Suzutani

“…HCMV is generally asymptomatic but causes severe disease in immunocompromised patients or infants who are congenitally infected. Recent advances in sequencing technology have led to the rapid expansion of the HCMV genetic database, providing a comprehensive resource for studying viral genetics. …”
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Lesion Distribution and Epidemiology of Mycobacterium bovis in Elk and White-Tailed Deer in South-Western Manitoba, Canada by Todd K. Shury, Doug Bergeson

“…Period prevalence in elk was approximately six times higher than deer, suggesting a significant reservoir role for elk, but that infected deer may also be involved. Prevalence was consistently higher in elk compared to deer in a small core area and prevalence declines since 2003 are likely due to a combination of management factors instituted during that time. …”
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