Diverse biological roles of PhoP/PhoQ in Pseudomonas plecoglossicida: Impact on stress responses and virulence by Meiqin Mao, Li He, Xiangyang Lin, Jianshao Wu, Pan Wang, Chuanzhong Zhu, Qingpi Yan

“…Among these, genes related to flagellar assembly, two-component systems, type III secretion systems, and bacterial chemotaxis were downregulated, while genes involved in ABC transport, magnesium ion transport, type VI secretion systems, and membrane permeability were upregulated. In artificial infection experiments, the ΔphoQ strain showed significantly reduced virulence when infecting hybrid grouper (Epinephelus fuscoguttatus♀ × E. lanceolatus♂), with an LD50 value of 3.931 × 104 cfu/mL. …”
Get full text

Seroprevalence of SARS-CoV-2 virus antibodies and sociodemographic features of pregnant women in Mogadishu, Somalia: a cross-sectional survey study by Maryan Abdullahi Sh. Nur, Hassan Abdullahi Dahie, Nima Abdi Hassan, Bashiru Garba, Jamal Hassan Mohamoud, Najib Isse Dirie, Mohamed Hussein Adam

“…Hence, the urgent need to understand the prevalence rate and level of awareness about COVID-19 (SARS-CoV-2 virus infection) and the practice of preventive measures against the disease among pregnant women in Somalia. …”
Get full text

Clinical evidence based review and recommendations of aerosol generating medical procedures in otolaryngology – head and neck surgery during the COVID-19 pandemic by Andrew Thamboo, Jane Lea, Doron D. Sommer, Leigh Sowerby, Arman Abdalkhani, Christopher Diamond, Jennifer Ham, Austin Heffernan, M. Cai Long, Jobanjit Phulka, Yu Qi Wu, Phillip Yeung, Marc Lammers

“…During the COVID-19 pandemic, it is essential for HCWs to recognize which procedures are potentially aerosolizing so that appropriate infection prevention precautions can be taken. The aim of this literature review was to identify potential AGMPs in Otolaryngology - Head and Neck Surgery and provide evidence-based recommendations. …”
Get full text

<i>Candida auris</i> Antifungal Resistance, Virulence and Susceptibility to a Novel Nitric Oxide-Releasing Microparticle and Its Correlations to Clade Identification by Alessandro F. Valdez, Flora Bohner, Joshua P. Goldman, Ali B. Jaquiery, Eduardo V. C. do Amaral, Dario Correa-Junior, Andrew Draganski, Leonardo Nimrichter, Joshua D. Nosanchuk, Daniel Zamith-Miranda

“…Additionally, the clade 2 strain was more susceptible to treatment with the microparticle, while also being more virulent in an invertebrate model of infection. Our findings were then correlated to visualize parallels between clade identification and resistance/virulence patterns.…”
Get full text

CD40 Ligand Potentiates Immunogenecity of <i>Mycoplasma pneumoniae</i> Subunit Vaccine Candidate in a Murine Model by Jinqi Shu, Gaojian Li, Jianhong Shu, Huapeng Feng, Yulong He

“…<i>Mycoplasma hyopneumoniae</i> (Mhp) infection severely affects the daily weight gain and feed-to-meat ratio of pigs, while secondary infections with other pathogens can further lead to increased mortality, causing significant economic losses to the pig industry. …”
Get full text

Virulence diversity of the yellow rust pathogen population in Dagestan by E. I. Gultyaeva, E. L. Shaydayuk, R. E. Smirnova, K. M. Abdullaev, K. U. Kurkiev

“…Age-specific resistance of virulence testers under high natural infection pressure was studied in the field of DES VIR. …”
Get full text

Effects of Prone Positioning for Patients with Acute Respiratory Distress Syndrome Caused by Pulmonary Contusion: A Single-Center Retrospective Study by Xiaoyi Liu, Hui Liu, Shilian Liu, Wenlai Zhou, Qing Lan, Jun Duan, Xue Li, Xiangde Zheng

Get full text

Functional Prediction of Hypothetical Proteins from and Validation of the Predicted Models by Using ROC Curve Analysis by Md. Amran Gazi, Sultan Mahmud, Shah Mohammad Fahim, Mohammad Golam Kibria, Parag Palit, Md. Rezaul Islam, Humaira Rashid, Subhasish Das, Mustafa Mahfuz, Tahmeed Ahmeed

“…Our comprehensive analysis will help to gain greater understanding for the development of many novel potential therapeutic interventions to defeat Shigella infection.…”
Get full text

Multi-environment field trials for wheat yield, stability and breeding progress in Germany by Tien-Cheng Wang, Till Rose, Holger Zetzsche, Agim Ballvora, Wolfgang Friedt, Henning Kage, Jens Léon, Carolin Lichthardt, Frank Ordon, Rod J Snowdon, Andreas Stahl, Hartmut Stützel, Benjamin Wittkop, Tsu-Wei Chen

“…Beside grain yield, ten agronomic traits, four baking quality traits, plant height, heading date, maturity date and six fungal disease infection indices are included. Additionally, we provide management records, including fertilizer use, plant protection measures, irrigation, and weather data. …”
Get full text

Measles and Pregnancy: Immunity and Immunization—What Can Be Learned from Observing Complications during an Epidemic Year by Rosalia Ragusa, Armando Platania, Mario Cuccia, Gaetano Zappalà, Gabriele Giorgianni, Placido D’Agati, Maria Alessandra Bellia, Marina Marranzano

“…Unvaccinated pregnant women are not only at risk of infection but also at risk of severe pregnancy complications. …”
Get full text

Macrophage P2X7 Receptor Function Is Reduced during Schistosomiasis: Putative Role of TGF-β1 by Suellen D’arc Santos Oliveira, Hayandra Ferreira Nanini, Luiz Eduardo Baggio Savio, Mariana Caldas Waghabi, Claudia Lucia Martins Silva, Robson Coutinho-Silva

“…Furthermore, P2X7-mediated increases in intracellular Ca2+ levels were also reduced in macrophages from infected mice. TGF-β1 levels were increased in the peritoneal cavity of infected animals, and pretreatment of control macrophages with TGF-β1 reduced ATP-induced permeabilization, mimicking the effect of S. mansoni infection. …”
Get full text

Virological and Immunological Aspects of AIDS Pathogenesis by Brian Conway, Francisco J Diaz-Mitoma

“…In an initial study of 70 patients. proviral load/ 106 CD4 cells was clearly associated with the severity of immune disease. with up to 9.6% of cells being infected in subjects with CD4 cell counts below 200/µL. …”
Get full text

Stage-specific function of sphingolipid synthases in African trypanosomes by Norton Heise, Carolina M. Koeller, Mohamed Sharif, James D. Bangs

“…These findings raise interesting questions about the roles of individual phosphosphingolipids in in vivo infection of the mammalian and tsetse hosts.IMPORTANCEAfrican trypanosomes are eukaryotic pathogens that cause human and veterinary African trypanosomaisis. …”
Get full text

Spray-Induced Gene Silencing (SIGS): Nanocarrier-Mediated dsRNA Delivery Improves RNAi Efficiency in the Management of Lettuce Gray Mold Caused by <i>Botrytis cinerea</i> by Maria Spada, Claudio Pugliesi, Marco Fambrini, Diego Palpacelli, Andrea Caneo, Susanna Pecchia

“…The SIGS approach was evaluated to control <i>B. cinerea</i> infection on lettuce plants. In vitro-synthesized dsRNA molecules (<i>BcBmp1</i>-, <i>BcBmp3</i>-, and <i>BcPls1</i>-dsRNAs) were used naked, or complexed to small layered double hydroxide (sLDH) clay nanosheets. …”
Get full text

Mycobacterium avium subsp. paratuberculosis in an Italian Cohort of Type 1 Diabetes Pediatric Patients by Maria Luisa Manca Bitti, Speranza Masala, Francesca Capasso, Novella Rapini, Simona Piccinini, Federica Angelini, Andrea Pierantozzi, Roberta Lidano, Silvia Pietrosanti, Daniela Paccagnini, Leonardo A. Sechi

“…The aim of this study was to investigate the prevalence of MAP infection in a T1D cohort from continental Italy compared with healthy control subjects. 247 T1D subjects and 110 healthy controls were tested for the presence of MAP. …”
Get full text

Kejadian Gangguan Depresi pada Penderita HIV/AIDS yang Mengunjungi Poli VCT RSUP Dr. M. Djamil Padang Periode Januari - September 2013 by Yaslinda Yaunin, Rudi Afriant, Nurul Maulidya Hidayat

“…<br />Kata kunci: penderita HIV/AIDS, gangguan depresi, poli VCT</p><p>Abstract<br />HIV/AIDS infection is associated with depression disorders. …”
Get full text

Using machine learning models to plan HIV services: Emerging opportunities in design, implementation and evaluation by T Dzinamarira, E Mbunge, I Chingombe, D F Cuadros, E Moyo, I Chitungo, G Murewanhema, B Muchemwa, G Rwibasira, O Mugurungi, G Musuka, H Herrera

“…However, barriers such as lack of engagement, limited availability of early HIV-infection detection tools, high rates of HIV/sexually transmitted infections (STIs), barriers to access antiretroviral therapy, lack of innovative resource optimisation and distribution strategies, and poor prevention services for vulnerable populations still exist and substantially affect the attainment of the UNAIDS 95-95-95 targets. …”
Get full text

Management of Splenic Abscess after Splenic Arterial Embolization in Severe Acute Pancreatitis: A 5-Year Single-Center Experience by Gang Li, Lin Gao, Jing Zhou, Bo Ye, Jingzhu Zhang, Cheng Qu, Lu Ke, Zhihui Tong, Weiqin Li

“…One patient died due to uncontrolled infection and another patient died due to massive bleeding, and the remaining sixteen patients survived. …”
Get full text

Factors Associated With Adolescents' Human Papillomavirus Vaccination Intention: A Cross‐Sectional Survey by Angela Chia‐Chen Chen, ChengChing Hiya Liu, Kimberly Arcoleo, Jiying Ling, Lorraine B. Robbins

“…Nurses play a critical role in protecting adolescents from HPV infection and related cancers. Digital interventions addressing HPV vaccine‐related risks and facilitators and engaging key personnel (adolescent, parent, healthcare provider, teacher) in different settings have the potential to increase adolescent's vaccination intention. …”
Get full text

Prevalence and Intensity of Gastrointestinal Parasites in Donkeys in Selected Abattoirs in Kenya by Nancy Mulwa, Samuel Githigia, Davis Karanja, Cecilia Mbae, Eberhard Zeyhle, Erastus Mulinge, Japhet Magambo, Kennedy Ogolla

“…A significant percentage (55.3%) had no eggs in their feces, 39% had low infection, 5% had medium, and only 0.7% were heavily infected. …”
Get full text