Outcome of dual implantation in distal end femur fractures among patients attending a tertiary care hospital in Karnataka by Kumar SVA, Vishnuprasad SH, Vittal V, Diwakar P, Zai SAK

“…Complications occurred in 60.0%, mainly limb length discrepancy (43.3%), valgus deformity (36.7%), and infection (16.7%). There is no statistically significant difference in outcome between type of fractures and dual implants used. …”
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Outpatient Intravenous Antibiotic Therapy: The Vancouver Hospital experience by Grant Stiver, Amy Wai, Lynne Chase, Luciana Frighetto, Carlo Marra, Peter Jewessen

“…Ninety-two of 107 patients treated in the VHHSC program completed their course uneventfully with resolution of the infection. The average duration of hospital therapy was 10.9 days versus 23.6 days of outpatient therapy. …”
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Population genetics studies of <i>Puccinia striiformis</i> f. sp. <i>tritici</i> in Dagestan and Northwestern Russia by E. L. Shaydayuk, D. R. Yakovleva, K. M. Abdullaev, V. P. Pyukkenen, E. I. Gultyaeva

“…In 2020, the resistance of differential sets was tested in the field in Derbent under a high natural infection pressure. SCAR markers were used to identify the invasive PstS1 and PstS2 isolates. …”
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Exploiting gasdermin-mediated pyroptosis for enhanced antimicrobial activity of phage endolysin against Pseudomonas aeruginosa by Dorota Kuc-Ciepluch, Karol Ciepluch, Daria Augustyniak, Grzegorz Guła, Barbara Maciejewska, Artur Kowalik, Ewelina Jop, Zuzanna Drulis-Kawa, Michał Arabski

“…The obtained results suggest the limited possibility of using the natural process of pyroptosis occurring in monocytic cells to enhance the bactericidal effect of recombinant phage endolysins against Gram-negative bacteria infection.…”
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Acute kidney injury in critically ill COVID-19 patients in a tertiary hospital: short and long-term kidney and patient outcomes by Juliana Alves Manhães de Andrade, Gisele Meinerz, Raphael Palma, Eduardo Rech, Marco Antônio Vinciprova Dall’Agnese, Cristiane Bundchen, Fernanda Bordignon Nunes, Gisele Branchini, Elizete Keitel

“…Female gender (p = 0.047), older age (p = 0.047), AKI stage 3 (p = 0.005), requirement of KRT (p < 0.0001), mechanical ventilation (p < 0.0001), and superimposed bacterial infection (p < 0.0001) were significantly associated death within 90 days. …”
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HIV risk perception and changes in sexual behavior and sexual satisfaction following male circumcision among circumcised males and their female partners from a traditionally noncir... by Barbara Burmen, Kennedy Mutai, George Otieno Olilo

“…Most of (≥ 90%) all men and women believed that circumcised men are less likely to get HIV infection and felt that both reducing the number of sex partners, and condom use with a partner with unknown HIV status were still necessary despite male circumcision (MC) being available in their community. …”
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Comparison of characteristics and immune responses between paired human nasal and bronchial epithelial organoids by Lu Zhu, Wenhao Yang, Jiaxin Luo, Danli Lu, Yanan Hu, Rui Zhang, Yan Li, Li Qiu, Zelian Chen, Lina Chen, Hanmin Liu

“…RNA sequencing analysis of differentially expressed genes indicated a significant reduction in the immune response in NO. RSV infection revealed more productive replication in NO, with a downregulated immune pathway identified by RNA sequencing analysis and upregulated levels of pro-inflammatory cytokines in culture supernatants in NO compared to BO. …”
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Extended spectrum betalactamase and Carbapenemase producing gram negative bacteria from healthcare workers gowns at Debre Berhan Comprehensive Specialized Hospital, Ethiopia by Sisay Gebrish Sharew, Daniel Gebretsadik Weldehanna, Demissew Shenkute Gebreyes, Tsegahun Asfaw Abebe, Agumas Shibabaw

“…Gowns used by healthcare workers (HCWs) in daily practice are a source of hospital-acquired infections in hospital settings. The study aimed to determine the prevalence of extended-spectrum beta-lactamase and carbapenemase-producing gram-negative bacteria from gowns of healthcare workers at Debre Berhan Comprehensive Specialized Hospital, Amhara Regional State, Ethiopia. …”
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Considerations and experiences with healthcare-seeking during the first COVID-19 lockdown in Denmark by Isabella Raasthøj Holst, Lisa Maria Sele Sætre, Gitte Bruun Lauridsen, Kirubakaran Balasubramaniam, Peter Haastrup, Sonja Wehberg, Dorte Ejg Jarbøl

“…Being worried about burdening the healthcare system was most frequently reported (45%), followed by being in doubt about acceptable contact reasons (33%), and concern about infection (24%). Although 44% of those who needed to contact their GP found the digital solutions advantageous, individuals frequently found it difficult to discuss symptoms by telehealth (29%) and that they were examined less thoroughly. …”
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Onchocerciasis is not a major cause of blindness in two endemic villages in Sierra Leone by Ibrahim Kargbo-Labour, Victoria Redwood-Sawyerr, Abdulai Conteh, Doris Harding, Mohamed S. Bah, Patricia Houck, Sugandh Juneja, Achille Kabore, Darin Evans, Angela M. Weaver, Yaobi Zhang

“…However, otoscopic eye examinations and microscopic skin snip tests were all negative for Onchocerca volvulus microfilariae, indicating no active or low-intensity infection among adults and a low or zero risk of serious ocular morbidity in the two villages. …”
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SARS-CoV-2 Evolution: Implications for Diagnosis, Treatment, Vaccine Effectiveness and Development by Fabrizio Angius, Silvia Puxeddu, Silvio Zaimi, Serena Canton, Sepehr Nematollahzadeh, Andrea Pibiri, Ilenia Delogu, Gualtiero Alvisi, Meng Ling Moi, Aldo Manzin

“…We further discuss vaccine safety in pregnancy and the implications of hybrid immunity on long-term protection against infection, as well as the latest developments on a pan-coronavirus vaccine and nasal formulations, emphasizing the need for continued surveillance, research, and adaptive public health strategies in response to the ongoing SARS-CoV-2 evolution race.…”
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Lactobacillus gasseri LGV03-derived indole-3-lactic acid ameliorates immune response by activating aryl hydrocarbon receptor by Zikang Zhang, Kangdi Zheng, Zhao Zhang, Longbin Cao, Lizhu Lin, Weimin Sun, Feng Qiu

“…Our previous research has shown that Lactobacillus gasseri LGV03 (L. gasseri LGV03) isolated from cervico-vagina of HPV-cleared women contributes to clearance of HPV infection and beneficially regulate immune response. …”
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Temperature Effect Study on Growth and Survival of Pathogenic Vibrio parahaemolyticus in Jinjiang Oyster (Crassostrea rivularis) with Rapid Count Method by Yuan Wang, Hai-yan Zhang, Essy Kouadio Fodjo, Cong Kong, Run-Run Gu, Feng Han, Xiao-Sheng Shen

“…The growth of Vibrio parahaemolyticus (V. parahaemolyticus) in oysters during postharvest storage increases the possibility of its infection in humans. In this work, to investigate the growth or survival profiles in different media, pathogenic V. parahaemolyticus in APW, Jinjiang oyster (JO, Crassostrea rivularis) slurry, and live JO were studied under different temperatures. …”
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Clinical characteristics and risk factors to high-grade vaginal intraepithelial neoplasia: a single-institution study by Min Lu, Xiaoshan Hong, Tingyan Liu, Bi Mai, Guiying Hu, Xiaoli Sun

“…Single-genotype HPV infections were observed in 58.4% of high‐grade VaIN and 64.3% of high‐grade CIN, while multiple infections were found in 39.6% and 32.8%, respectively. …”
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Pasteurisation temperatures effectively inactivate influenza A viruses in milk by Jenna Schafers, Caroline J. Warren, Jiayun Yang, Junsen Zhang, Sarah J. Cole, Jayne Cooper, Karolina Drewek, B. Reddy Kolli, Natalie McGinn, Mehnaz Qureshi, Scott M. Reid, Thomas P. Peacock, Ian Brown, Joe James, Ashley C. Banyard, Munir Iqbal, Paul Digard, Edward Hutchinson

“…This includes human and avian influenza A viruses (IAVs), an influenza D virus that naturally infects cattle, and recombinant IAVs carrying contemporary avian or bovine H5N1 glycoproteins. …”
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A comparative study between central quadrantectomy and nipple resection with areola preservation Versus Grisotti flap mammoplasty in central breast lesions extending to nipple: a r... by Philobater Bahgat Adly Awad, Basma Hussein Abdelaziz Hassan, Abanoub Adel Shafek Awad, Abdelrahman Ahmed Younis Mohamed Attaia, Kerolos Bahgat Adly Awad, Dina Mohamed Hanafy, Ahmed Gamal El Din Osman

“…Regarding, the wound infection was found in one case (5%) in group (I) and 3(15%) cases in group II (p = 0.605). …”
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Nucleosome patterns in four plant pathogenic fungi with contrasted genome structures by Clairet, Colin, Lapalu, Nicolas, Simon, Adeline, Soyer, Jessica L., Viaud, Muriel, Zehraoui, Enric, Dalmais, Berengère, Fudal, Isabelle, Ponts, Nadia

“…Control of fungal diseases on crops necessitates a global understanding of fungal pathogenicity determinants and their expression during infection. Genomes of phytopathogenic fungi are often compartmentalized: the core genome contains housekeeping genes whereas the fast-evolving genome mainly contains transposable elements and species-specific genes. …”
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Tuberculosis and COVID-19: Lessons from the Past Viral Outbreaks and Possible Future Outcomes by Radu Crisan-Dabija, Cristina Grigorescu, Cristina-Alice Pavel, Bogdan Artene, Iolanda Valentina Popa, Andrei Cernomaz, Alexandru Burlacu

“…Because viral respiratory infections and TB impede the host’s immune responses, it can be assumed that their lethal synergism may contribute to more severe clinical evolution. …”
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Effectiveness of Kaempferia galanga extract for the prevention of saprolegniasis on catfish Clarias gariepinus eggs by Arvilia Humsari, , Rosidah, , Junianto

“…ABSTRACT Saprolegniasis is a disease caused by the infection of Saprolegnia sp. Saprolegniasis can attack catfish eggs causing a decrease in hatching rate. …”
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Age-dependent differences in the association between blood interleukin-6 levels and mortality in patients with sepsis: a retrospective observational study by Takashi Shimazui, Takehiko Oami, Tadanaga Shimada, Keisuke Tomita, Taka-aki Nakada

“…Elderly patients have blunted and easily dysregulated host responses to infection, which may influence IL-6 kinetics and alter the association between IL-6 levels and clinical outcomes. …”
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