Medial sural artery perforator free flap for small- to medium-sized defects in head and neck reconstruction: a suitable replacement for radial forearm free flap by Yulian Zhang, Keran Pan, Jian Wu, Xi Tang

“…The patient and flap characteristics (age, sex, flap size, harvest time, etc.) and outcomes (success rate, donor site complications including infection, hematoma, and fistula, donor site morbidity including abnormal sensation, weakness, range of motion, postoperative oral function) were recorded and compared. …”
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Acute kidney injury and outcomes in hospitalized children with autoimmune rheumatic disease by Chien-Hung Lin, Wen-Sheng Liu, Chuan Wan, Hsin-Hui Wang

“…Children with SSc had increased risks of infection/pneumonia (aOR = 2.51, 95% CI: 1.84–3.41) and sepsis (aOR = 2.13, 95% CI: 1.26–3.58). …”
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Inhalation of multiple pen caps causing bronchial foreign bodies: a rare case in an older child by Jia Zhai, Yongsheng Guo, Chunlei Chen, Xuelin Wang, Yifan Wang, Ying-Xue Zou

“…The patient was started on anti-infective therapy to address any underlying infection before proceeding with removal. …”
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Metabolic Perturbations and Severe COVID-19 Disease: Implication of Molecular Pathways by Ersilia Nigro, Fabio Perrotta, Rita Polito, Vito D’Agnano, Filippo Scialò, Andrea Bianco, Aurora Daniele

“…In addition, the role of the main biological processes that may connect metabolic alterations to SARS-CoV-2 infection such as hyperglycemia, immune system deregulation, ACE-2 receptor modulation, and inflammatory response is described. …”
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Clinical evaluation and management of a 45-year-old man with confusion, psychosis, agitation, stereotyped behavior, and impaired speech by Xiaolin Deng, Paulo J. Negro, Patrick L. Jung, Christopher M. Marano, Stephanie Knight, Seshagiri R. Doddi, Nana Y. A. Nimo, Rachel M. LeMalefant, Drew A. Myers, Andrea K. Haake, Rebecca Chandler

“…He incurred a lumbar spinal injury due to a motor vehicle incident in his 20s which led to weakness, numbness, and frequent infection over both of his lower extremities. He also developed alcohol addiction over the course of his life. …”
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Mpox and the men who have sex with men (MSM) community in Nigeria: Exploratory insights from MSM and persons providing healthcare services to them by Michael Kunnuji, Megan Schmidt-Sane, Olufunke Adegoke, Syed Abbas, Elizabeth Shoyemi, Akanni O. Lawanson, Ayodele Jegede, Hayley MacGregor

“…Intimate contact during sexual intercourse is a likely source of infection among MSM. The Nigerian mpox response does not centre MSM, and centreing them may not be ideal due to potential stigma. …”
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Technical considerations towards commercialization of porcine respiratory and reproductive syndrome (PRRS) virus resistant pigs by A. Mark Cigan, Pieter W. Knap

“…Rather than backcrossing the resistance gene from a few non-commercial founders, as a global supplier of high genetic merit livestock genetics, Genus plc and its pig division PIC (Pig Improvement Company) with Genus R&D have mobilized advances in reproductive biology, gene editing, DNA sequencing, and bioinformatics to simultaneously generate and introduce a single modified CD163 allele across four genetically diverse porcine lines of commercial importance that prevents PRRS virus (PRRSV) infection. This report focuses on technical aspects for a scaled gene editing program to consider for rapid and efficient generation and advancement of a small population of non-transgenic founder pigs for commercial breeding. …”
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Daratumumab for autoimmune diseases: a systematic review by Martin Krusche, Ina Kötter, Lennard Ostendorf, Nikolas Ruffer, Marie-Therese Holzer, Tobias B. Huber

“…Adverse events were reported in 45% of patients including application-associated reaction (20%), infection (19%) and hypogammaglobulinaemia (33%).Conclusion Targeting CD38 via daratumumab is a new promising therapeutic option in therapy refractory autoimmune diseases. …”
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A Rare Case of Pylephlebitis as a Complication of Cholecystocolonic Fistula by Kouki Imaoka, Saburo Fukuda, Hirofumi Tazawa, Sotaro Fukuhara, Yuzo Hirata, Seiji Fujisaki, Mamoru Takahashi, Hideto Sakimoto

“…Pylephlebitis is defined as a septic thrombophlebitis of the portal vein and its tributaries that is associated with multiple suppurative abdominal infections. We report a case of pylephlebitis associated with a cholecystocolonic fistula (CCF). …”
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Real-Life Report on Chemoembolization Using DEBIRI for Liver Metastases from Colorectal Cancer by M. Stutz, A. Mamo, D. Valenti, A. Hausvater, T. Cabrera, P. Metrakos, P. Chaudhury, G. Steacy, E. Garoufalis, P. Kavan

“…Hospitalization was also required for 1 case of allergic reaction and 1 case of infection. Conclusion. Our data suggest that TACE with DEBIRI could be efficacious in a palliative setting for patients with LMCRC, but they do not necessarily support routine use in clinical practice.…”
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Bacteriological Analysis of Raw Beef Retailed in Selected Open Markets in Accra, Ghana by Michael Olu-Taiwo, Prince Obeng, Akua Obeng Forson

“…Conclusively, effective monitoring of the bacteriological profiles and bacterial loads of meat and meat products in abattoirs and points of sale should be established, since such a continuous monitoring system could help prevent potential health problems for consumers and provide information on possible sources of meat borne intoxication and infection.…”
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Vaccine-induced reduction of COVID-19 clusters in school settings in Japan during the epidemic wave caused by B.1.1.529 (Omicron) BA.2, 2022 by Yuta Okada, Hiroshi Nishiura

“…We first estimated the protected (immune) fraction of each age group either by infection or vaccination and then linked the case count in each age group to the number of clusters via a time series regression model that accounts for the time-varying hazard of clustering per infector. …”
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Inflammation and ER Stress Downregulate BDH2 Expression and Dysregulate Intracellular Iron in Macrophages by Susu M. Zughaier, Brandon B. Stauffer, Nael A. McCarty

“…Hepcidin is the master iron regulating hormone that limits dietary iron absorption from the gut and limits iron egress from macrophages. Upon infection macrophages retain iron to limit its bioavailability which limits bacterial growth. …”
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Analysis and Characterization of the Immunogenicity of Rhoptry Protein 18 by Masoud Foroutan, Amir Karimipour-Saryazdi, Ali Dalir Ghaffari, Hamidreza Majidiani, Arezo Arzani Birgani, Elaheh Karimzadeh-Soureshjani, Shahrzad Soltani, Hany M Elsheikha

“…Rhoptry protein 18 (ROP18) is a key virulence factor secreted into host cells during the invasion of Toxoplasma gondii ( T. gondii ) and plays an important role in the pathogenesis of infection. Due to its potential as a vaccine candidate, this study aimed to characterize several properties of the T. gondii ROP18 (TgROP18) protein to support its inclusion in vaccine formulations. …”
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Role of Chest Radiography in Diagnosing Pulmonary Tuberculosis, Does Every Suspected Case Needs GeneXpert MTB; A Cross-Sectional Study by Mujahid Raza, Saleh Khurshied, Altaf Hussain, Nawal Khurshid, Ali Khurshid

“… Background: Pulmonary tuberculosis (TB) triggers a common infection globally. Chest X-ray (CXR) plays a role in diagnosis of pulmonary TB and has typical findings. …”
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Post-translational modifications as a key mechanism for herpes simplex virus type I evasion of host innate immunity by Yongxing Zhang, Junlei Xie, Ying Feng, Abdul Qadeer, Shanni Li, Xu Deng, Lipeng Zhu, Bo Kong, Zanxian Xia, Zanxian Xia

“…Herpes simplex virus type 1 (HSV-1) is a DNA virus that infects humans and establishes long-term latency within the host. …”
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Coexistence of Virulence Factors and Efflux Pump Genes in Clinical Isolates of Pseudomonas aeruginosa: Analysis of Biofilm-Forming Strains from Iran by Shahram Shahraki Zahedani, Hamed Tahmasebi, Mojdeh Jahantigh

“…In this study, biofilm formation and EP’s collaborative role in clinical isolates of P. aeruginosa infection were investigated. Methods. Eighty-six (86) P. aeruginosa isolates were collected from different clinical specimens and were confirmed using different biochemical tests. …”
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Optic Neuritis in an Adult Patient with Chickenpox by Ana Rita Azevedo, Rita Simões, Filipe Silva, Susana Pina, Cristina Santos, Peter Pêgo, Filomena Silva, Susana Teixeira

“…Central nervous system involvement in a patient with primary infection with Varicella zoster virus is rare, especially in the immunocompetent adult. …”
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Antiulcer Effect of Genus Symphytum L. and Portulaca oleracea L. as Investigated on Experimental Animals by El-Sayed H. Bakr, Amal Al-Ghamdi, Reham Al-Amri, Muna Al-Otaibi, Nada Al-Saad, Ghala Al-Matrafi, Ziad T. Kishmira, Firas Azzeh, Areej A. Almuraee

“…Peptic ulcer disease (PUD) occurs when open sores, or ulcers, form in the stomach or first part of the small intestine caused by bacterial infection (H. pylori) and/or nonsteroidal anti-inflammatory drug (NSAID) use. …”
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Case report: Tongue metastasis as an initial sign of clear cell renal cell carcinoma and its prognosis by Shuo Liu, Hongyun Liu, Bowen Weng, Sichuan Hou

“…His disease progressed to progressive disease (PD), and he ultimately succumbed to systemic infection, with a progression-free survival (PFS) of approximately 15 months. …”
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