Deciphering the Multifaceted Relationship between Oncolytic Viruses and Natural Killer Cells by Christopher A. Alvarez-Breckenridge, Jianhua Yu, Balveen Kaur, Michael A. Caligiuri, E. Antonio Chiocca

“…The immune response to viral infection appears to be an essential factor that determines the efficacy of oncolytic viral therapy. …”
Get full text

Influence of Gallic Acid and Thai Culinary Essential Oils on Antibacterial Activity of Nisin against Streptococcus mutans by Pimsumon Jiamboonsri, Pimpikar Kanchanadumkerng

“…These results suggest that GA and KLL oil may be potentially used as an adjunctive therapy along with nisin and chlorhexidine to control S. mutans infection.…”
Get full text

Exploring nagZ as a virulence biomarker and treatment target in Enterobacter cloacae by Xianggui Yang, Xuejing Yu, Li Zhou, Dan Wang, Weixian Chen

“…Our research showed that pathogenic strains of E. cloacae express higher levels of nagZ than colonizing strains, particularly in simulated infection environments. Deleting nagZ significantly reduced E. cloacae virulence in various infection models, including Galleria mellonella larvae, mice, and RAW264.7 cells. …”
Get full text

Challenges in Emerging Vaccines and Future Promising Candidates against SARS-CoV-2 Variants by Tanmay Ghildiyal, Nishant Rai, Janhvi Mishra Rawat, Maargavi Singh, Jigisha Anand, Gaurav Pant, Gaurav Kumar, Amrullah Shidiki

“…Since the COVID-19 outbreak, the severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) virus has evolved into variants with varied infectivity. Vaccines developed against COVID-19 infection have boosted immunity, but there is still uncertainty on how long the immunity from natural infection or vaccination will last. …”
Get full text

Helicobacter pylori Pathogenicity Factors Related to Gastric Cancer by Kianoosh Dadashzadeh, Maikel P. Peppelenbosch, Akyala Ishaku Adamu

“…Our results show an elevated prevalence of infection with H. pylori strains carrying known virulence genotypes with high genetic diversity. …”
Get full text

Nonprofessional Phagocytosis Can Facilitate Herpesvirus Entry into Ocular Cells by Vaibhav Tiwari, Deepak Shukla

“…Our findings suggest a novel mechanism by which the nonprofessional mediators of phagocytosis can be infected by human herpesviruses.…”
Get full text

Peritoneal Tuberculosis With a Challenging Diagnosis: A Case Report by Parivash Davoodian, Adel Sadeghdoost, Khadijeh Ahmadi, Behnoosh Heidari

“…Extra-pulmonary TB, especially in the gastrointestinal tract, is often a difficult and delayed diagnosis because it can mimic metastasis or infection. Diagnostic problems can delay appropriate treatment and play a role in TB transmission. …”
Get full text

Hantavirus pulmonary syndrome in Santa Cruz, Bolivia: outbreak investigation and antibody prevalence study. by Joel M Montgomery, Patrick J Blair, Darin S Carroll, James N Mills, Alberto Gianella, Naomi Iihoshi, Ana M Briggiler, Vidal Felices, Milagros Salazar, James G Olson, Raisa A Glabman, Daniel G Bausch

“…The first case was a physician infected with Laguna Negra virus during a weekend visit to his ranch. …”
Get full text

Inborn errors of immunity (primary immunodeficiencies) by Vy H. D. Kim, Julia E. M. Upton, Beata Derfalvi, Kyla J. Hildebrand, Christine McCusker

“…Although the clinical manifestations of IEIs are highly variable, traditionally many disorders involve an increased susceptibility to infection. Research in recent years has underscored how IEI can present with features other than infection such as: severe atopy, autoimmunity, autoinflammation, lymphoproliferation, and/or malignancy resulting from immune dysregulation. …”
Get full text

Actinomyces Acute Rhinosinusitis Complicated by Subperiosteal Abscess in an Immunocompromised 12-Year-Old: Case Report and Literature Review by Sai V. Nimmagadda, Li-Xing Man, Margo K. McKenna, John J. Faria, Isaac L. Schmale

“…Actinomycosis of the paranasal sinuses poses a diagnostic challenge, with infections varying widely in presentation and extent of disease. …”
Get full text

Prevalence of CagA-positive Helicobacter pylori strain and H. pylori-associated gastritis activity in Tuva schoolchildren of different age groups by Tamara V. Polivanova, Vitaly A. Vshivkov

“…Age-related increase in CagA-positive H pylori infection in specific ethnic group was insignificant. …”
Get full text

Fatal H1N1-Related Acute Necrotizing Encephalopathy in an Adult by Yu-Jin Lee, D. Scott Smith, Vivek A. Rao, Robert D. Siegel, Jon Kosek, Carol A. Glaser, Alexander C. Flint

“…Acute necrotizing encephalopathy (ANE) is a severe neurological complication of influenza infection, including H1N1 influenza. Many cases of ANE have been reported in the pediatric literature, but very few cases have been described in adults. …”
Get full text

Pantoea agglomerans Bacteremia: Is It Dangerous? by Ikwinder Preet Kaur, Sindhura Inkollu, Amulya Prakash, Haresh Gandhi, Mohsin Sheraz Mughal, Doantrang Du

“…The wound was healing, without active infection. Chest X-ray and CT scan of abdomen and pelvis to rule out infection were negative. …”
Get full text

Hubungan Nilai Laju Endap Darah (LED) dengan Kadar C-Reactive Protein (C-RP) pada Pasien Positif Covid-19 by Yumna Tahani Tsamarah, I Gusti Ayu Nyoman Danuyanti, Siti Zaetun

“…SARS-CoV-2 infection is a systemic infection that significantly affects hematopoiesis and the patient's immune response. …”
Get full text

HTLV-1 Tax-mediated inhibition of FOXO3a activity is critical for the persistence of terminally differentiated CD4+ T cells. by David Olagnier, Alexandre Sze, Samar Bel Hadj, Cindy Chiang, Courtney Steel, Xiaoying Han, Jean-Pierre Routy, Rongtuan Lin, John Hiscott, Julien van Grevenynghe

“…De novo HTLV-1 infection of CD4+ T cells or direct lentiviral-mediated introduction of Tax led to AKT activation and AKT-dependent inactivation of FOXO3a, via phosphorylation of residues Ser253 and Thr32. …”
Get full text

The effects of variable spatial aggregation on lymphatic filariasis transmission by Callum Shaw, Angus McLure, Kathryn Glass

“…With the addition of spatial structure, residual infections remained in limited groups, and infection resurgence was slowed. …”
Get full text

Ovine Paratuberculosis: A Seroprevalence Study in Dairy Flocks Reared in the Marche Region, Italy by Attili Anna Rita, Ngu Ngwa Victor, Preziuso Silvia, Pacifici Luciana, Domesi Anastasia, Cuteri Vincenzo

“…MAP infection was confirmed in 12.6% of infected farms by faecal culture. …”
Get full text

Modern modes of chronic hepatitis C treatment by V. T. Ivashkin, M. V. Mayevskaya, M. A. Morozova, Ye. O. Lyusina

“…Nowadays conventional «gold standard» treatment of chronic HCV-infection is antiviral therapy by pegilated interferon and ribavirin combination. …”
Get full text

Molecular and Phylogenetic Analysis of Bovine Papillomavirus Type 1: First Report in Iraqi Cattle by Mohammed A. Hamad, Ahmed M. Al-Shammari, Shoni M. Odisho, Nahi Y. Yaseen

“…This study presents the first report of BPV-1 infection in the Iraqi cattle and contributes to extending the knowledge of the origin of the spread of this disease. …”
Get full text

Strongyloides Hyperinfection in a Renal Transplant Patient: Always Be on the Lookout by Murtaza Mazhar, Ijlal Akbar Ali, Nelson Iván Agudelo Higuita

“…Strongyloides infection in renal transplant patient is very rare and often presents with hyperinfection, associated with high mortality rates. …”
Get full text