Synthesis, characterization, and evaluation of copper-doped zinc oxide nanoparticles anticancer effects: in vitro and in vivo experiments by Habib Ghaznavi, Mohammad Reza Hajinezhad, Zahra Hesari, Milad Shirvaliloo, Saman Sargazi, Sheida Shahraki, Eshagh Ali Saberi, Roghayeh Sheervalilou, Somayeh Jafarinejad

Get full text

Impedance mapping with high-density microelectrode array chips reveals dynamic heterogeneity of in vitro epithelial barriers by Alessandra Venz, Bastien Duckert, Liesbet Lagae, Saeedeh Ebrahimi Takalloo, Dries Braeken

“…Abstract Epithelial tissues in vitro undergo dynamic changes while differentiating heterogeneously on the culture substrate. …”
Get full text

<i>In vitro</i> and <i>in vivo</i> tropism and biodistribution of recombinant simian adenovirus type 25 by Irina V. Vavilova, Tatiana A. Ozharovskaia, Olga V. Zubkova, Olga Popova, Daria V. Voronina, Polina P. Goldovskaya, Denis I. Zrelkin, Alina Sh. Dzharullaeva, Inna V. Dolzhikova, Dmitry V. Shcheblyakov, Denis Yu. Logunov, Alexander L. Gintsburg

“…The aim of this study was to investigate the cellular tropism of the simian adenovirus type 25 in vitro and its biodistribution in vivo in comparison with human adenoviruses types 5 and 26. …”
Get full text

Revolutionizing precision medicine in oral squamous cell carcinoma: Harnessing 3D in vitro models for translation by Nitesh Buldak, Vishnu Priya Veeraraghavan, Ullas Mony

“…In recent years, three-dimensional (3D) in vitro models have emerged as powerful tools to study OSCC biology and evaluate targeted therapies in a more physiologically relevant context. …”
Get full text

Development and characterization of in vitro inducible immortalization of a murine microglia cell line for high throughput studies by Hana Yeh, Matthew A. De Cruz, Yang You, Seiko Ikezu, Tsuneya Ikezu

“…Treatment with transforming growth factor-β modified the transcriptome of the 2E11 cell line, affecting cellular immune pathways. Our findings indicate that the 2E11 inducible immortalized cell line is a practical and convenient tool for studying microglial biology in vitro.…”
Get full text

Effects of Self-Assembled Monolayers with Different Chemical Groups on Ovarian Cancer Cell Line Behavior In Vitro by Jie Li, Ting Guan, Chenjun Hao, Lihua Li, Yu Zhang

Get full text

A novel lidocaine-chitosan-barium titanate microemulsion gel for prolonged local anesthesia: An in vitro study by Qiao Xiaoru, Li Ling

“…Virgin oil was used as an auxiliary oil to increase the microemulsion area, allowing for a reduced amount of surfactant. In vitro analysis was conducted to evaluate the release of lidocaine from the microemulsion. …”
Get full text

Synthesis, Characterization, and In Vitro Drug Delivery Capabilities of (Zn, Al)-Based Layered Double Hydroxide Nanoparticles by Vinay J. Nagaraj, Xiaodi Sun, Jiten Mehta, Mac Martin, Thi Ngo, Sandwip K. Dey

Get full text

Cell Surface Proteins for Enrichment and In Vitro Characterization of Human Pluripotent Stem Cell-Derived Myogenic Progenitors by Sin-Ruow Tey, Madison Mueller, Megan Reilly, Colton Switalski, Samantha Robertson, Mariko Sakanaka-Yokoyama, Masatoshi Suzuki

Get full text

UDP-Induced Phagocytosis and ATP-Stimulated Chemotactic Migration Are Impaired in STIM1−/− Microglia In Vitro and In Vivo by Hye Min Lim, Heo Woon, Jung Woo Han, Yoshihiro Baba, Tomohiro Kurosaki, Min Goo Lee, Joo Young Kim

“…Microglial functions regulated by chronic and global Ca2+i changes were reduced significantly, including cytokine releases and opsonin-dependent phagocytosis. More dramatically, cellular functions governed by Ca2+ regulation in local microdomains at the cell periphery, such as UDP-induced phagocytosis and ATP-stimulated chemotactic migration, were severely reduced in STIM1−/− microglia. …”
Get full text

Effects of Hyaluronic Acid on Three Different Cell Types of the Periodontium in a Novel Multi-Culture Cell Plate: An Exploratory Study by Alessio Barbieri, Luciano Pitzurra, Bruno Loos, Ineke D. C. Jansen

“…The proliferation and function of the periodontal ligament fibroblasts were not changed by HA or the cellular interplay. The use of multi-culture plates could represent a promising method to investigate and compare dental biomaterials in experiments mimicking an in vivo environment.…”
Get full text

Advances in Microengineered Platforms for Skin Research by Sireesh Kumar Teertam, Vijayasaradhi Setaluri, Jose M. Ayuso

“…Compared with traditional in vitro models, microfluidic platforms offer improved control of fluid flow, which in turn allows precise manipulation of cell and molecular distribution. …”
Get full text

Advancements in Bone Replacement Techniques–Potential Uses After Maxillary and Mandibular Resections Due to Medication-Related Osteonecrosis of the Jaw (MRONJ) by Judit Bovari-Biri, Judith A Miskei, Zsanett Kover, Alexandra Steinerbrunner-Nagy, Kinga Kardos, Peter Maroti, Judit E Pongracz

“…While various biomaterial scaffolds have shown promise in addressing these challenges, regenerating bone in this region remains complex due to its irregular shape, intricate structure, and differing cellular origins compared to other bones in the human body. …”
Get full text

In vitro effect of hCG on cryptorchid patients’ gubernacular cells: a predictive model for adjuvant personalized therapy by Andrea Errico, Giulia Ambrosini, Sara Vinco, Emanuela Bottani, Elisa Dalla Pozza, Nunzio Marroncelli, Jessica Brandi, Daniela Cecconi, Ilaria Decimo, Filippo Migliorini, Nicola Zampieri, Ilaria Dando

“…On these in vitro cultured cells, we analyzed the effect of hCG on cell proliferation, tubular structure formation, cellular respiration, reactive oxygen species content, and proteome. …”
Get full text

The Effect of an Aqueous Extract of Teucrium polium on Glutathione Homeostasis In Vitro: A Possible Mechanism of Its Hepatoprotectant Action by Stella Shtukmaster, Predrag Ljubuncic, Arieh Bomzon

Get full text

Expression Profiling of Long Noncoding RNA Splice Variants in Human Microvascular Endothelial Cells: Lipopolysaccharide Effects In Vitro by Imran H. Chowdhury, Hema P. Narra, Abha Sahni, Kamil Khanipov, Casey L. C. Schroeder, Jignesh Patel, Yuriy Fofanov, Sanjeev K. Sahni

Get full text

In Vitro Analyses Reveal the Effect of Synthetic Cytokinin Forchlorfenuron (FCF) on a Septin-Like Protein of Taeniid Cysticerci by Diana G. Rios-Valencia, Edgar O. López-Villegas, Dylan Diaz Chiguer, Adrian Marquez Navarro, Ruben D. Díaz-Martín, Benjamin Nogueda-Torres, Javier R. Ambrosio

“…In addition, we observed by ultrastructural observation that FCF alters the cellular subunit of the protonephridial system of cestodes, where disruption of the axoneme pattern of flame cells was observed. …”
Get full text

In vitro immunomodulatory effects of thymol and cinnamaldehyde in a pig intestinal epithelial cell line (IPEC-J2) by C. Shen, L.G. Christensen, P.B. Rasmussen, K.M. Kragh

“…This study evaluated the in vitro immune modulating effects of thymol and cinnamaldehyde blend (TCB) in a porcine gut epithelial cell line (IPEC-J2), with or without cellular damage caused by challenge with lipopolysaccharides. …”
Get full text

Effect of Inflammation on Gingival Mesenchymal Stem/Progenitor Cells’ Proliferation and Migration through Microperforated Membranes: An In Vitro Study by M. Al Bahrawy, K. Ghaffar, A. Gamal, K. El-Sayed, V. Iacono

Get full text

Development and in vitro evaluation of biomimetic injectable hydrogels from decellularized human nerves for central nervous system regeneration by Gopal Agarwal, Kennedy Moes, Christine E. Schmidt

Get full text