AFP shields hepatocellular carcinoma from macrophage phagocytosis by regulating HuR-mediated CD47 translocation in cellular membrane by Yinglian Pan, Qiushi Yin, Zhaoliang Wang, Gang Wu, Kun Liu, Xiaowei Li, Jinchen Liu, Jiangzheng Zeng, Bo Lin, Wei Li, Mingyue Zhu, Mengsen Li

“…In this study, explore AFP regulates macrophage immunomodulation in hepatocellular carcinoma(HCC) through comprehensive in vitro and in vivo studies. Methods: Immunohistochemical and immunofluorescence staining was used to analyze the relativity of AFP and cellular membrane CD47 expression in clinical 30 HCC tissues, and the expression of AFP and CD47 in HCC cells. …”
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Effect of In Vitro Exposure of Corticosteroid Drugs, Conventionally Used in AMD Treatment, on Mesenchymal Stem Cells by Raffaele Nuzzi, Monica Gunetti, Deborah Rustichelli, Barbara Roagna, Francesca Fronticelli Bardelli, Franca Fagioli, Ivana Ferrero

“…In conclusion, this in vitro study demonstrated that high doses of corticosteroid drugs have a negative effect on MSCs, reduced in the presence of a conditioned media.…”
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Effects of exogenous selenium application on quality characteristics, selenium speciation, and in vitro bioaccessibility of rice pancakes by Feiran An, Kun Zhuang, Lingling Shangguan, Lan Yao, Jun Dai

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Assessment of Transformed Properties In Vitro and of Tumorigenicity In Vivo in Primary Keratinocytes Cultured for Epidermal Sheet Transplantation by A. Thépot, A. Desanlis, E. Venet, L. Thivillier, V. Justin, A. P. Morel, F. DeFraipont, M. Till, V. Krutovskikh, M. Tommasino, O. Damour, P. Hainaut

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How cells align to structured collagen fibrils: a hybrid cellular Potts and molecular dynamics model with dynamic mechanosensitive focal adhesions by Koen A. E. Keijzer, Erika Tsingos, Erika Tsingos, Roeland M. H. Merks, Roeland M. H. Merks

“…Many mammalian cells, including endothelial cells and fibroblasts, align and elongate along the orientation of extracellular matrix (ECM) fibers in a gel when cultured in vitro. During cell elongation, clusters of focal adhesions (FAs) form near the poles of the elongating cells. …”
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Mesenchymal stem cell‐derived exosomes mitigate amyloid β‐induced retinal toxicity: Insights from rat model and cellular studies by Amanda Qarawani, Efrat Naaman, Rony Ben‐Zvi Elimelech, Michal Harel, Shahaf Sigal‐Dror, Tali Ben‐Zur, Tamar Ziv, Daniel Offen, Shiri Zayit‐Soudry

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Immunobiotics Beneficially Modulate TLR4 Signaling Triggered by Lipopolysaccharide and Reduce Hepatic Steatosis In Vitro by Paulraj Kanmani, AbuZar Ansari, Julio Villena, Hojun Kim

“…Therefore, this study was conducted to evaluate lipid reduction and immunoregulatory potentials of probiotic bacteria in vitro. HepG2 cells treated with total cellular fluid (TCF) of LABs reduced lipid accumulation. …”
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Study on the In Vitro and In Vivo Antioxidant Activity and Potential Mechanism of <i>Polygonum viviparum</i> L. by Zhen Yang, Jingyuan Man, Haoyu Liu, Di Wu, Qiangwen Gu, Hongjuan Zhang, Yu Liu, Dan Shao, Baocheng Hao, Shengyi Wang

“…However, there are few studies that have focused on its antioxidant activity and mechanism of action in vitro and in vivo. Therefore, the present study firstly demonstrated that PV could exert good in vitro antioxidant effects by scavenging DPPH radicals and inhibiting the production of hydroxyl radicals through in vitro experiments. …”
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Anti-melanogenic effects of hydroxyethyl chrysin through the inhibition of tyrosinase activity: In vitro and in silico approaches by Yuna Lee, Ha-Yeon Song, Eui-Baek Byun

“…In the present study, we explored whether HE-chrysin has antioxidant and anti-melanogenic capacity using in vitro B16F10 murine melanoma cells and in silico molecular docking. …”
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In vitro evaluation of glutathione implementation on oxidative dna damage and oxidant status in high glucose conditions by Fatmagul Yur, Semiha Dede, Sedat Cetin, Mehmet Taspinar, Ayse Usta

“…<p> <b>Materials and Methods: </b>BHK-21 cell line was regularly surpassed in vitro conditions (5% FBS, 10% horse serum, 1% L-Glutamine, 1% penicillin/ streptomycin in RPMI 1640 medium, and 5% CO2 and 95% humidity and 37ºC) incubated. …”
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In Vitro Studies of Bacterial Cellulose and Magnetic Nanoparticles Smart Nanocomposites for Efficient Chronic Wounds Healing by Bianca Galateanu, Mihaela-Cristina Bunea, Paul Stanescu, Eugenia Vasile, Angela Casarica, Horia Iovu, Anca Hermenean, Catalin Zaharia, Marieta Costache

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Experimental Solution of Chitosan and Nanochitosan on Wettability in Root Dentine: In Vitro Model Prior Regenerative Endodontics by Fernando Arias Alvarado, Maira Rivero Iriarte, Freddy Jordan Mariño, Sara Quijano-Guauque, León D. Pérez, Yolima Baena, Claudia García-Guerrero

“…The wettability of the chemically modified dentin substrate is a condition that intervenes in dentin-vascular and cellular interaction across regenerative endodontics. …”
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Stryphnodendron adstringens have a modulatory effect on inflammatory cytokines markers of in vitro activated macrophages by Ivana Beatrice Mânica da Cruz, Cibele Ferreira Teixeira, Neida Luiza Pellenz, Moisés Henrique Mastella, Verônica Farina Azzolin, Euler Esteves Ribeiro, Fernanda Barbisan

“…This will be achieved using an in vitro protocol with the commercial macrophage cell line RAW 264.7. …”
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Two Cysteines in Raf Kinase Inhibitor Protein Make Differential Contributions to Structural Dynamics In Vitro by Hyun Sang Cho, Mohammad Faysal Al Mazid, Eun-Young Lee, Md Abu Rayhan, Hyoun Sook Kim, Byung Il Lee, Hye Jin You

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Quaternary ammoniums activate human dendritic cells and induce a specific T-cell response in vitro by Marine Peyneau, Mathilde Zeller, Virginie Paulet, Benoît Noël, Marie-Hélène Damiens, Natacha Szely, Andreas Natsch, Marc Pallardy, Sylvie Chollet-Martin, Luc de Chaisemartin, Saadia Kerdine-Römer

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Homologs of the rolC gene of naturally transgenic toadflaxes Linaria vulgaris and Linaria creticola are expressed in vitro by T. V. Matveeva, O. D. Bogomaz, L. A. Golovanova, Yu. S. Li, D. Dimitrov

“…Such plants are called naturally transgenic plants, and T-DNA in their genomes is called cellular (cT-DNA). It is proposed that in the evolution of these genera, the introduced sequences played an important role. …”
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Deciphering molecular and cellular ex vivo responses to bispecific antibodies PD1-TIM3 and PD1-LAG3 in human tumors by Alfred Zippelius, Petra Herzig, Pratiksha Gulati, Christian Klein, Marta Trüb, Kirsten D Mertz, Robert Rosenberg, Viola Heinzelmann-Schwarz, Mark Wiese, Didier Lardinois, Pablo Umana, Marina Natoli, Klas Hatje, Fabian Junker, Zhiwen Jiang, Iakov I Davydov, Markus Germann, Daniel Marbach, Adrian Zwick, Patrick Weber, Stefan Seeber, Lothar Tietze, Laura Codarri-Deak, Henry Kao

“…Yet, the molecular and cellular mechanisms by which either receptor functions to mediate its inhibitory effects are still poorly understood. …”
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Cellular Localization and Biochemical Characterization of a Chimeric Fluorescent Protein Fusion of Arabidopsis Cellulose Synthase-Like A2 Inserted into Golgi Membrane by Monica De Caroli, Marcello S. Lenucci, Gian-Pietro Di Sansebastiano, Michela Tunno, Anna Montefusco, Giuseppe Dalessandro, Gabriella Piro

“…Here we report a study on the cellular localization and the enzyme activity of an Arabidopsis CslA family member, AtCslA2. …”
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Toxicological Implications of Platinum Nanoparticle Exposure: Stimulation of Intracellular Stress, Inflammatory Response, and Akt Signaling In Vitro by Claudia J. Labrador-Rached, Rebecca T. Browning, Laura K. Braydich-Stolle, Kristen K. Comfort

“…As PtNPs have induced differential cellular responses in vitro, the goal of this study was to further characterize the behavior and toxicological potential of PtNPs within a HepG2 liver model. …”
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Age-Related Macular Degeneration (AMD) Transmitochondrial Cybrids Protected from Cellular Damage and Death by Human Retinal Progenitor Cells (hRPCs) by Jeffrey J. Yu, Daniel B. Azzam, Marilyn Chwa, Kevin Schneider, Jang-Hyeon Cho, Chinhui Hsiang, Henry Klassen, M. Cristina Kenney, Jing Yang

“…These in vitro data provide evidence that hRPCs may have therapeutic potential in atrophic AMD.…”
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