Role of antioxidants in skin aging and the molecular mechanism of ROS: A comprehensive review by Narmin Hama amin Hussen, Sakar Karem Abdulla, Naza Mohammed Ali, Van Abdulqader Ahmed, Aso Hameed Hasan, Eman Erfan Qadir

“…The systematic search was done for eligible articles which including in vivo and in vitro studies from studies between (1997 until 2024).…”
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Scutellarein Inhibits Osteosarcoma Growth by Targeting the TLR4/TRAF6/NF-κB Pathway by Shi Y, Tang Y, Sun Z, Sui P, Shao Y, Wang Z, Zhang J, Gao M

“…Molecular docking and cellular thermal shift assay were employed to confirm the binding interaction between SCU and TLR4. …”
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The influence of different crosslinking agents onto the physical properties, integration behavior and immune response of collagen-based barrier membranes by Yanru Ren, Said Alkildani, Kim Burckhardt, Alexander Köwitsch, Milena Radenkovic, Sanja Stojanovic, Sanja Stojanovic, Stevo Najman, Stevo Najman, Ole Jung, Luo Liu, Mike Barbeck, Mike Barbeck

“…This study investigates the mechanical properties as well as in vitro and in vivo cyto- and biocompatibility of collagen membranes cross-linked with glutaraldehyde (GA), proanthocyanidins (PC), hexamethylendiisocyanate (HMDI) and 1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide/N-hydroxysuccinimide (EC/NHS). …”
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LDHA-mediated glycolysis in stria vascularis endothelial cells regulates macrophages function through CX3CL1-CX3CR1 pathway in noise-induced oxidative stress by Ying Yi, Min-Yu Wu, Kai-Tian Chen, An-Hai Chen, Lin-Qiu Li, Qin Xiong, Xian-Ren Wang, Wen-Bin Lei, Guan-Xia Xiong, Shu-Bin Fang

“…In this study, we investigated the effects of glycolysis on SV-ECs in vitro and on the SV in vivo. Our previous research identified the glycolysis pathway as a potential mechanism underlying the SV-ECs injuries induced by oxidative stress. …”
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NKX6.3 modulation of mitotic dynamics and genomic stability in gastric carcinogenesis by Jung Hwan Yoon, Jeong-Kyu Kim, Jung Woo Eun, Hassan Ashktorab, Duane T. Smoot, Suk Woo Nam, Won Sang Park

“…Mitotic integrity and genomic stability are crucial in maintaining cellular homeostasis and preventing tumorigenesis. …”
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The role of Latin America medicinal plants in wound healing by Mariana Sánchez-Ramos, Andrea Ruiz-Betancourt, Stephany Abigail Tadeo-Cuenca, Angélica Román-Guerrero, María Crystal Columba-Palomares, Araceli Guerrero-Alonso, Antonio Bernabé-Antonio, Deyanira Ojeda-Ramírez, Francisco Cruz-Sosa

“…At a biological level, wound healing involves a complex mechanism in which the immune system and cellular biochemical cascades intervene in a coordinated manner, whose development occurs in stages such as inflammation, proliferation, and remodeling. …”
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Novel and potent MICA/B antibody is therapeutically effective in KRAS LKB1 mutant lung cancer models by Shohei Koyama, Yujiro Naito, John D Minna, David E Gerber, Ryan R Kowash, Manoj Sabnani, Laura T Gray, Qing Deng, Nusrat U A Saleh, Luc Girard, Kentaro Masahiro, Zhiqian Lucy Liu, Hemanta Baruah, Esra A Akbay

“…We performed in vitro assays using ELISA and flow cytometry-based assays to confirm that our antibody potently binds to and stabilizes MICA/B expression across lung cancer and other solid tumor cell lines. …”
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OSM May Serve as a Biomarker of Poor Prognosis in Clear Cell Renal Cell Carcinoma and Promote Tumor Cell Invasion and Migration by Shuzhang Wei, Yin Chen, Xiaokai Shi, Li Zuo, Lifeng Zhang

“…Also, the univariate and multivariate Cox analyses of clinical characteristics show that OSM in ccRCC may be able to predict a poor prognosis on its own as a biomarker. In vitro cellular experiments demonstrated that high OSM expression had no discernible impact on ccRCC cell proliferation compared to the control group, but it did promote tumor cell invasion and migration. …”
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Telomerase RNA structural heterogeneity in living human cells detected by DMS-MaPseq by Nicholas M. Forino, Jia Zheng Woo, Arthur J. Zaug, Arcelia Gonzalez Jimenez, Eva Edelson, Thomas R. Cech, Silvi Rouskin, Michael D. Stone

“…We propose that this misfolded portion of the cellular hTR pool is either slowly refolded or degraded, suggesting that kinetic RNA folding traps studied in vitro may also hinder ribonucleoprotein assembly in vivo.…”
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Development of Delivery Systems Enhances the Potency of Cell-Based HIV-1 Therapeutic Vaccine Candidates by Amin Hadi, Abbas Rastgoo, Maryam Eskandarian, Nooshin Haghighipour, Azam Bolhassani

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Preparation of Ginsenoside Rg3 and Protection against H2O2-Induced Oxidative Stress in Human Neuroblastoma SK-N-SH Cells by Gang Li, Xiao-xiao Zhang, Lin Lin, Xiao-ning Liu, Cheng-jun Ma, Ji Li, Chi-bo Wang

“…MTT assay and LDH leakage assay were used to determine the cell viability and the oxidative stress cellular model was established by means of H2O2 (600 μM for 4 h). …”
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Antihyperglycemic Activity of Eucalyptus tereticornis in Insulin-Resistant Cells and a Nutritional Model of Diabetic Mice by Alis Guillén, Sergio Granados, Kevin Eduardo Rivas, Omar Estrada, Luis Fernando Echeverri, Norman Balcázar

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CRP and TNF-α  Induce PAPP-A Expression in Human Peripheral Blood Mononuclear Cells by Weiping Li, Hongwei Li, Fusheng Gu

“…Human PBMCs are capable of expressing PAPP-A in vitro, expression that may be regulated by CRP and TNF-α through the NF-κB pathway. …”
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hUC-MSC extracellular vesicles protect against hypoxic-ischemic brain injury by promoting NLRP3 ubiquitination by Shanshan Xiao, Ying Lv, Xuejing Hou, Shuqiang Qu

“…Behavioral reflexes and brain infarction were assessed, along with cellular and molecular analyses of hippocampal tissue. …”
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Development and Characterization of an F-labeled Ghrelin Peptidomimetic for Imaging the Cardiac Growth Hormone Secretagogue Receptor by Ahmed Abbas MSc, Lihai Yu PhD, Tyler Lalonde BSc, Derek Wu BSc, Jonathan D. Thiessen PhD, Leonard G. Luyt PhD, Savita Dhanvantari PhD

“…We have synthesized and characterized a novel ghrelin peptidomimetic tracer, an 18 F-labeled analogue of G-7039, for positron emission tomography (PET) imaging of cardiac GHSR1a. In vitro analysis showed enhanced serum stability compared to natural ghrelin and significantly increased cellular uptake in GHSR1a-expressing OVCAR cells. …”
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Microglial Lyzl4 Facilitates β‐Amyloid Clearance in Alzheimer's Disease by Jie Pan, Jie Zhong, Ji Geng, Jane Oberhauser, Shihua Shi, Jun Wan

“…Furthermore, it is found that Lyzl4 overexpression boosts Aβ clearance both in vitro and in vivo, underscoring its potential for mitigating Aβ burden. …”
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FTO effects the proliferation, invasion, and glycolytic metabolism of colon cancer by regulating PKM2 by Kongyan Zhang, Fei Zhang, Jiahe Wang

“…Cellular behaviors such as proliferation, migration, invasion, and apoptosis were evaluated using various assays. …”
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Bioprinting of bespoke islet-specific niches to promote maturation of stem cell-derived islets by Myungji Kim, Seungyeon Cho, Dong Gyu Hwang, In Kyong Shim, Song Cheol Kim, Jiwon Jang, Jinah Jang

“…Abstract Pancreatic islets are densely packed cellular aggregates containing various hormonal cell types essential for blood glucose regulation. …”
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Human Cardiac Fibroblast Number and Activation State Modulate Electromechanical Function of hiPSC-Cardiomyocytes in Engineered Myocardium by Cassady E. Rupert, Tae Yun Kim, Bum-Rak Choi, Kareen L. K. Coulombe

“…It is well accepted that heterotypic cellular interactions impact the phenotype of cardiomyocytes. …”
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Effects of ketamine and propofol on muscarinic plateau potentials in rat neocortical pyramidal cells. by Anne S Fleiner, Daniel Kolnier, Nicholas Hagger-Vaughan, Johan Ræder, Johan F Storm

“…Ketamine is an N-methyl-D-aspartate (NMDA) receptor antagonist, while propofol is a γ-aminobutyric-acid (GABAA) receptor positive allosteric modulator, but these mechanisms do not fully explain how these drugs alter consciousness. Most previous in vitro studies of cellular mechanisms of anaesthetics have used brain slices or neurons in a nearly "comatose" state, because no "arousing" neuromodulators were added. …”
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