Tau oligomers impair memory and synaptic plasticity through the cellular prion protein by Claudia Balducci, Franca Orsini, Milica Cerovic, Marten Beeg, Beatrice Rocutto, Letizia Dacomo, Antonio Masone, Eleonora Busani, Ilaria Raimondi, Giada Lavigna, Po-Tao Chen, Susanna Leva, Laura Colombo, Chiara Zucchelli, Giovanna Musco, Nicholas M. Kanaan, Marco Gobbi, Roberto Chiesa, Luana Fioriti, Gianluigi Forloni

“…Evidence suggests that the cellular prion protein (PrPC) may act as a mediator of TauO neurotoxicity, as previously proposed for β-amyloid and α-synuclein oligomers. …”
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Stem Cells as In Vitro Model of Parkinson's Disease by Patricia L. Martínez-Morales, Isabel Liste

“…Progress in understanding neurodegenerative cell biology in Parkinson's disease (PD) has been hampered by a lack of predictive and relevant cellular models. In addition, the lack of an adequate in vitro human neuron cell-based model has been an obstacle for the uncover of new drugs for treating PD. …”
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Antiaging and Antioxidant Bioactivities of Asteraceae Plant Fractions on the Cellular Functions of the Yeast Schizosaccharomyces pombe by Rika Indri Astuti, Muhammad Eka Prastya, Irmanida Batubara, Eka Budiarti, Aulia Ilmiyawati

“…Based on the in vitro assay, the water fractions of S. trilobata showed a strong antioxidant activity. …”
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zIncubascope: Long-term quantitative imaging of multi-cellular assemblies inside an incubator. by Anirban Jana, Naveen Mekhileri, Adeline Boyreau, Aymerick Bazin, Nadège Pujol, Kevin Alessandri, Gaëlle Recher, Pierre Nassoy, Amaury Badon

“…Recent advances in bioengineering have made it possible to develop increasingly complex biological systems to recapitulate organ functions as closely as possible in vitro. Monitoring the assembly and growth of multi-cellular aggregates, micro-tissues or organoids and extracting quantitative information is a crucial but challenging task required to decipher the underlying morphogenetic mechanisms. …”
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Cellular Programming and Reprogramming: Sculpting Cell Fate for the Production of Dopamine Neurons for Cell Therapy by Julio C. Aguila, Eva Hedlund, Rosario Sanchez-Pernaute

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AHNAK2: a potential diagnostic biomarker for pancreatic cancer related to cellular motility by Mohamed Zardab, Barts Pancreas Tissue Bank, Richard P. Grose, Hemant M. Kocher

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in vitro activation of complement and contact system by lactic acidosis by J. Sonntag, M. Emeis, E. Strauss, M. Obladen

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In Vitro Effects of Strontium on Proliferation and Osteoinduction of Human Preadipocytes by V. Nardone, R. Zonefrati, C. Mavilia, C. Romagnoli, S. Ciuffi, S. Fabbri, G. Palmini, G. Galli, A. Tanini, M. L. Brandi

“…The aim of our study was to evaluate the in vitro effects of a wide range of strontium (Sr2+) concentrations on proliferation, ALP activity, and mineralization of a novel finite clonal hADSCs cell line, named PA20-h5. …”
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In Vitro Mechanism of Action of Acanthospermum hispidum in Trypanosoma brucei by Aboagye Kwarteng Dofuor, Temitayo Samson Ademolue, Karen Nana Akua Kuampah, Frederick Ayertey, Theresa Manful Gwira

“…This study aimed to investigate the cellular mechanisms of antitrypanosomal and antioxidant activities of A. hispidum against Trypanosoma brucei (T. brucei), a causative protozoan species of African trypanosomiasis. …”
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Navigating from cellular phenotypic screen to clinical candidate: selective targeting of the NLRP3 inflammasome by Rosalie Matico, Karolien Grauwen, Dhruv Chauhan, Xiaodi Yu, Irini Abdiaj, Suraj Adhikary, Ine Adriaensen, Garcia Molina Aranzazu, Jesus Alcázar, Michela Bassi, Ellen Brisse, Santiago Cañellas, Shubhra Chaudhuri, Francisca Delgado, Alejandro Diéguez-Vázquez, Marc Du Jardin, Victoria Eastham, Michael Finley, Tom Jacobs, Ken Keustermans, Robert Kuhn, Josep Llaveria, Jos Leenaerts, Maria Lourdes Linares, Maria Luz Martín, Rosa Martín-Pérez, Carlos Martínez, Robyn Miller, Frances M Muñoz, Michael E Muratore, Amber Nooyens, Laura Perez-Benito, Mathieu Perrier, Beth Pietrak, Jef Serré, Sujata Sharma, Marijke Somers, Javier Suarez, Gary Tresadern, Andres A Trabanco, Dries Van den Bulck, Michiel Van Gool, Filip Van Hauwermeiren, Teena Varghese, Juan Antonio Vega, Sameh A Youssef, Matthew J Edwards, Daniel Oehlrich, Nina Van Opdenbosch

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Development and assessment of an intestinal tri-cellular model to investigate the pro/anti-inflammatory potential of digested foods by Marina Ramal-Sanchez, Chiara Bravo-Trippetta, Veronica D’Antonio, Elena Corvaglia, Angela A. M. Kämpfer, Roel P. F. Schins, Mauro Serafini, Donato Angelino

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Epigenetic Changes in Endothelial Progenitors as a Possible Cellular Basis for Glycemic Memory in Diabetic Vascular Complications by Poojitha Rajasekar, Christina L. O’Neill, Lydia Eeles, Alan W. Stitt, Reinhold J. Medina

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Synthesis, in vitro safety and antioxidant activity of new pyrrole hydrazones by Tzankova Diana, Vladimirova Stanislava, Aluani Denitsa, Yordanov Yordan, Peikova Lily, Georgieva Maya

“…The antioxidant protective potential of the compounds was next determined in different in vitro cellular-based models, revealing compounds 4d and 3 [ethyl 5-(4-bromophenyl)-1-(1-hydrazineyl-1-oxo-3-phenylpropan-2-yl)-2-methyl-1H-pyrrole-3-carboxylate] as the most promising compounds, with 4d having better safety profile.…”
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In vitro antitumor effects of methanolic extracts of three Ganoderema mushrooms by Elshahat A. Toson, Amira A. El-Fallal, Marwa A. Oransa, Hoda M. El-Gharabawy

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Urothelial Differentiation of Human Umbilical Cord-Derived Mesenchymal Stromal Cells In Vitro by Shuai Wu, Zhongliang Cheng, Guohua Liu, Xinfeng Zhao, Liang Zhong, Yingjian Zhu, Jiang Zhu

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Immortalized Mesenchymal Stem Cells: A Safe Cell Source for Cellular or Cell Membrane-Based Treatment of Glioma by Yuxuan Zhang, Jie Liu, Yunzhao Mo, Zetao Chen, Taoliang Chen, Yan Li, Yaofeng Zheng, Shaokang Deng, Xiangdong Xu, Huajian Chen, Haoqi He, Jiansheng Chen, Tao Jin, Xinlin Sun, Yiquan Ke, Jihui Wang

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Stimulation of Alpha1-Adrenergic Receptor Ameliorates Cellular Functions of Multiorgans beyond Vasomotion through PPARδ by Yong-Jik Lee, Hyun Soo Kim, Hong Seog Seo, Jin Oh Na, You-Na Jang, Yoon-Mi Han, Hyun-Min Kim

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The Effect of Cyclooxygenase Inhibition on Tendon-Bone Healing in an In Vitro Coculture Model by Tim Schwarting, Sebastian Pretzsch, Florian Debus, Steffen Ruchholtz, Philipp Lechler

“…We examined the effects of selective COX-2 and nonselective COX inhibition on bone-tendon integration in an in vitro model. We measured the dose-dependent effects of ibuprofen and parecoxib on the viability of lipopolysaccharide- (LPS-) stimulated and unstimulated mouse MC3T3-E1 and 3T3 cells, the influence on gene expression at the osteoblast, interface, and fibroblast regions measured by quantitative PCR, and cellular outgrowth assessed on histological sections. …”
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In Vitro Vitamin K3 Effect on Conjunctival Fibroblast Migration and Proliferation by I. Pinilla, L. B. Izaguirre, F. J. Gonzalvo, E. Piazuelo, M. A. Garcia-Gonzalez, A. I. Sanchez-Cano, F. Sopeña

“…There were no differences among groups at the initial time. In vitro wound repair was slower in groups 4, 5, and 6. …”
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A STUDY OF THE INFLUENCE OF EXTRACELLULAR VESICLES ON THE MORPHOFUNCTIONAL STATE OF THE ENDOMETRIUM IN VITRO by Оксана Александровна Мелкозерова, Ирина Викторовна Крутинь, Александра Юрьевна Храмцова, Мария Валерьевна Улитко, Алсу Фармутовна Мустафина

“…Despite the long history of assisted reproductive technologies (ART), the effectiveness of in vitro fertilization (IVF) programs remains at the level of 30-40%. …”
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