Antibacterial and Cytotoxic Effects of Moringa oleifera (Moringa) and Azadirachta indica (Neem) Methanolic Extracts against Strains of Enterococcus faecalis by Lucía Arévalo-Híjar, Miguel Ángel Aguilar-Luis, Stefany Caballero-García, Néstor Gonzáles-Soto, Juana Del Valle-Mendoza

“…To evaluate antibacterial and cytotoxic effect of 2 methanolic extracts of Azadirachta indica and Moringa oleifera against strains of Enterococcus faecalis (ATCC 29212) in vitro. Methods. The methanolic extracts of Azadirachta indica and Moringa oleifera were prepared in vitro. …”
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Nonclinical immunogenicity risk assessment for knobs-into-holes bispecific IgG1 antibodies by Wen-Ting K. Tsai, Yinyin Li, Zhaojun Yin, Peter Tran, Qui Phung, Zhenru Zhou, Kun Peng, Dan Qin, Sien Tam, Christoph Spiess, Jochen Brumm, Manda Wong, Zhengmao Ye, Patrick Wu, Sivan Cohen, Paul J. Carter

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Fluorescence Lifetime Imaging of NAD(P)H in Patients’ Lymphocytes: Evaluation of Efficacy of Immunotherapy by Diana V. Yuzhakova, Daria A. Sachkova, Anna V. Izosimova, Konstantin S. Yashin, Gaukhar M. Yusubalieva, Vladimir P. Baklaushev, Artem M. Mozherov, Vladislav I. Shcheslavskiy, Marina V. Shirmanova

“…In this regard, the selection of an appropriate in vitro model and the choice of cellular response assay are critical for reliable predictions. …”
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Patient-derived xenografts from circulating cancer stem cells as a preclinical model for personalized pancreatic cancer research by Benedikt J. Wagner, Andreas Ettner-Sitter, Nicolas A. Ihlo, Merle Behr, Sebastian Koelbl, Stefan M. Brunner, Florian Weber, Bettina M. Rau, Hans J. Schlitt, Christoph Brochhausen, Rebecca Schoenmehl, Annalena Artinger, Dorothea Schott, Monika Pizon, Katharina Pachmann, Thiha Aung, Silke Haerteis, Christina Hackl

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Effects of linsitinib on M22 and IGF:1-treated 3D spheroids of human orbital fibroblasts by Fumihito Hikage, Megumi Suzuki, Tatsuya Sato, Araya Umetsu, Toshifumi Ogawa, Nami Nishikiori, Masato Furuhashi, Hiroshi Ohguro, Megumi Watanabe

“…Lins had effects similar to those of IGF1/M22 on cellular biological functions of HOFs but not on those of GHOFs. …”
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Optimizations of Placenta Extracellular Matrix‐Loaded Silk Fibroin/Alginate 3D‐Printed Scaffolds Structurally and Functionally for Bone Tissue Engineering by Zahra Bashiri, Zahra Khosrowpour, Ali Moghaddaszadeh, Davod Jafari, Sanaz Alizadeh, Hajar Nasiri, Houman Parsaei, Zahra Keshtkaran, Meghdad Abdollahpour‐Alitappeh, Farshad Bargrizaneh, Behzad Rezaei, Sara Simorgh, Mazaher Gholipourmalekabadi

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Gold Nanorods Targeted to Delta Opioid Receptor: Plasmon-Resonant Contrast and Photothermal Agents by Kvar C. Black, Nathaniel D. Kirkpatrick, Timothy S. Troutman, Liping Xu, Josef Vagner, Robert J. Gillies, Jennifer K. Barton, Urs Utzinger, Marek Romanowski

“…Molecularly targeted gold nanorods were investigated for applications in both diagnostic imaging and disease treatment with cellular resolution. The nanorods were tested in two genetically engineered cell lines derived from the human colon carcinoma HCT-116, a model for studying ligand-receptor interactions. …”
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Synthesis and Evaluation of Some New Isoquine Analogues for Antimalarial Activity by Chandra Nath Saha, Sanjib Bhattacharya, Dipak Chetia

“…The drug toxicity involves the formation of an electrophilic metabolite, amodiaquine quinoneimine (AQQI), which binds to cellular macromolecules leading to hepatotoxicity and agranulocytosis. …”
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Biological Characteristics of Fluorescent Superparamagnetic Iron Oxide Labeled Human Dental Pulp Stem Cells by Liang Ma, Ming-wei Li, Yu Bai, Hui-hui Guo, Sheng-chao Wang, Qing Yu

“…Tracking transplanted stem cells is necessary to clarify cellular properties and improve transplantation success. …”
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A three-dimensional mouse liver organoid platform for assessing EDCs metabolites simulating liver metabolism by Ji Hyun Moon, Hyun-Soo Roh, Young Jae Park, Hyun Ho Song, Jieun Choi, Da Woon Jung, Soo Jin Park, Ho Jin Park, So-Hyeon Park, Da-Eun Kim, Gahee Kim, Joong-Hyuck Auh, Dong Ha Bhang, Hong Jin Lee, Do Yup Lee

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Radiation Induces Apoptosis and Osteogenic Impairment through miR-22-Mediated Intracellular Oxidative Stress in Bone Marrow Mesenchymal Stem Cells by Zhonglong Liu, Tao Li, Si’nan Deng, Shuiting Fu, Xiaojun Zhou, Yue He

“…Intervention with antioxidant (NAC) indicated that IR-induced cellular apoptosis was partly due to the accumulation of intracellular ROS. …”
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Decoding CKD-induced muscle atrophy through the critical role of lncRNA GAS5 and pyroptosis by Rong Huang, Xinying Tang, Shuang Liu, Lijing Sun

“…Our findings provide new evidence for GAS5’s role in regulating cellular pyroptosis in CKD-induced skeletal muscle atrophy.…”
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The role of Mitofusin-1 and Mitofusin-2 in periodontal disease: a comprehensive review by Sudhir R. Varma, Sudhir R. Varma, Omar H. A. A. Ani, Jayaraj K. Narayanan, Jayaraj K. Narayanan, Asok Mathew, Asok Mathew

“…Data from chosen in vivo, clinical studies, and in vitro were synthesized. Outcomes indicate that MFN2 and MFN1 are important for preserving cellular function, mitigating oxidative damage, and mitochondrial fusion. …”
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The role of size in PEGylated liposomal doxorubicin biodistribution and anti‐tumour activity by Saba Dadpour, Amin Mehrabian, Mahdieh Arabsalmani, Elaheh Mirhadi, Anis Askarizadeh, Mohammad Mashreghi, Mahmoud Reza Jaafari

“…First, 100, 200, and 400 nm PLDs were prepared by remote loading procedure and characterised for their size, zeta potential, encapsulation efficacy, and release properties. Then, in vitro cellular uptake and cytotoxicity were studied by flow cytometry and MTT assay, and compared with commercially available PLD Caelyx®. …”
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Effects of Severe Hypoxia on Bone Marrow Mesenchymal Stem Cells Differentiation Potential by Claudia Cicione, Emma Muiños-López, Tamara Hermida-Gómez, Isaac Fuentes-Boquete, Silvia Díaz-Prado, Francisco J. Blanco

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Integrative analysis of single-cell and transcriptome sequencing with experimental validation reveals PKHD1L1 as a novel biomarker in lung adenocarcinoma by Xiangqian Zhang, Jie Wang, Hanyang Su, Xiaojin Liu

“…In vitro experiments revealed that the over-expression of PKHD1L1 significantly inhibited the proliferation and migration ability of LUAD cell lines. …”
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Integrating single-cell RNA-Seq and bulk RNA-Seq data to explore the key role of fatty acid metabolism in hepatocellular carcinoma by Hua Dai, Xin Tao, Yuansen Shu, Fanrong Liu, Xiaoping Cheng, Xiushen Li, Bairui Shu, Hongcheng Luo, XuXiang Chen, Zhaorui Cheng

“…Subsequent to its identification, cellular communication analysis was employed to assess the immunological attributes of PTGES3 within the tumor microenvironment. …”
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Related Pentacyclic Triterpenes Have Immunomodulatory Activity in Chronic Experimental Visceral Leishmaniasis by Jéssica Adriana de Jesus, Márcia Dalastra Laurenti, Leila Antonangelo, Caroline Silvério Faria, João Henrique Ghilardi Lago, Luiz Felipe Domingues Passero

“…(L.) infantum; additionally, both triterpenes activated cellular immune response in the hamster model of visceral leishmaniasis.…”
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MAZ-mediated tumor progression and immune evasion in hormone receptor-positive breast cancer: Targeting tumor microenvironment and PCLAF+ subtype-specific therapy by Gaofeng Ni, Yuwei Sun, Hongling Jia, Zhikai Xiahou, Yumeng Li, Fu Zhao, Hongyan Zang

“…Cellular communication dynamics between tumor cell subtypes and other cells were analyzed with the CellChat. …”
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MSC-sEVs exacerbate senescence by transferring bisecting GlcNAcylated GPNMB by Yihan Ma, Chongfu Zhao, Jingjing Feng, Junjie Gou, Enci Kang, Feng Guan, Qiong Wu, Xiang Li

“…Glycoprotein non-metastatic melanoma protein B (GPNMB), a type I transmembrane glycoprotein, is upregulated during cellular senescence and can regulate stem cell ageing. …”
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