Preparation of oat galactolipid and anti-liver cancer effects of oat galactolipid–modified curcumin-loaded liver targeting vesicle by Huiying Ren, Nuo Chen, Yanqing Liu, Meimei Wu, Meimei Wu, Meimei Wu, Jingsong Yan, Jingsong Yan, Jingsong Yan, Mingxiang Chang, Mingxiang Chang, Mingxiang Chang, Hanmin Li, Hanmin Li, Hanmin Li

“…IntroductionThe mortality rate for liver cancer is extremely high but clinical treatments have not made much progress, so it is necessary to develop anticancer agents with lower toxicities and more effective liver-targeting drug delivery systems (LTDDSs). …”
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Linking winter wheat (Triticum aestivum L) root traits and root water uptake with electrical resistivity tomography by Huijie Gu, Yanzhe Wang, Luca Peruzzo, Baoru Li, Yang Lu, Xiuwei Liu

“…Field experiments conducted during the grain-filling phase, when root size was stable, showed significant differences in soil ER changes (defined as the difference between two consecutive ER measurements) among winter wheat cultivars in both shallow (0–40 cm) and deep (40–100 cm) soil layers under various irrigation treatments. It was observed that wheat tends to utilize deep soil moisture in later growth stages, even with sufficient water conditions. …”
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Loss of MEF2C function by enhancer mutation leads to neuronal mitochondria dysfunction and motor deficits in mice by Ali Yousefian-Jazi, Suhyun Kim, Jiyeon Chu, Seung-Hye Choi, Phuong Thi Thanh Nguyen, Uiyeol Park, Min-gyeong Kim, Hongik Hwang, Kyungeun Lee, Yeyun Kim, Seung Jae Hyeon, Hyewhon Rhim, Hannah L. Ryu, Grewo Lim, Thor D. Stein, Kayeong Lim, Hoon Ryu, Junghee Lee

“…This genetic and epigenetic crosstalk mechanism provides insights for advancing our understanding of motor neuron disease and developing effective treatments.…”
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A study on the effect of biostimulant application on yield and quality of tomato under long-lasting water stress conditions by Cristina Patanè, Alessandra Pellegrino, Alessandro Saita, Silvio Calcagno, Salvatore L. Cosentino, Alessio Scandurra, Valeria Cafaro

“…PCA analysis allowed to distribute cultivars and treatments in four distinct groups, according to quality traits. …”
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Exploring the allometry between ear saturated water accumulation and dry mass for diagnosing winter wheat water status during the reproductive growth by Tingxuan Zhuang, Ben Zhao, Syed Tahir Ata-Ul-Karim, Gilles Lemaire, Xiaojun Liu, Yongchao Tian, Yan Zhu, Weixing Cao, Qiang Cao

“…Field experiments involving four water and two nitrogen treatments were conducted from 2019 to 2023 to determine the relationship between ear dry mass (EDM) and SWAE during the reproductive growth phase of winter wheat. …”
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Proteasome inhibition enhances oncolytic reovirus therapy in multiple myeloma independently of its direct cytotoxic effects by Ada Alice Dona, Theophilus Tandoh, Lokesh Nigam, Mahmoud Singer, Enrico Caserta, Mariam Murtadha, Yinghui Zhu, Milad Moloudizargari, Preeti Sharma, Ottavio Napolitano, Janet Winchester, Arnab Chowdhury, Alex Pozhitkov, James F. Sanchez, Hawa Vahed, Guido Marcucci, Matt Coffey, Gerard Nuovo, Douglas W. Sborov, Flavia Pichiorri, Craig C Hofmeister

“…Immune fluorescence, flow cytometry, and luciferase reporter assays were used to assess NF-κB pathway activation upon RV treatments. Immune profiling changes, both ex vivo and in MM patients, were analyzed by flow cytometry and CyTOF analysis. …”
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Quantitative N-glycoproteomic analysis reveals glycosylation signatures of plasma immunoglobulin G in systemic sclerosis by Lu Cheng, Lu Cheng, Yanhong Li, Yu Zhou, Yingying Ling, Tong Wu, Zongan Liang, Yinlan Wu, Chunyu Tan, Yi Liu, Yong Zhang

“…Systemic sclerosis (SSc) is a perplexing autoimmune disorder, characterized by mysterious causes, high mortality rates, and a lack of effective treatments. The role of abnormal glycosylation in the onset of autoimmune diseases has been recognized for some time. …”
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Effects of different monochromatic light on growth performance and liver circadian rhythm of Yangzhou geese by Yingqing Xu, Yi Tang, Yiyi Cheng, Wen Yang, Jie Liu, Binbin Guo, Gang Luo, Huanxi Zhu

“…After undergoing the four photochromic treatments, both plasma melatonin levels and liver positive feedback clock gene expression displayed a diurnal low-night high pattern, reaching their peak in the evening. …”
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Retrospective Analysis of the Prevalence and Risk Factors of Retinopathy of Prematurity in a Single-Center Cohort in Romania and Comparison with National and European Data by Zsuzsánna Simon-Szabó, Sándor Pál, Aliz Pándi, Zsuzsanna Gáll, Hajnal Finta, Zsuzsánna Incze-Bartha, Cristina Maki, Manuela Cucerea

“…In those found to have stage 2 and 3 ROP in zone II with plus disease (n = 6), intravitreal anti-VEGF injections and/or retinal laser treatments were performed. Notably, no cases of ROP-related blindness were recorded. …”
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Increased methane production associated with community shifts towards Methanocella in paddy soils with the presence of nanoplastics by Zhibin He, Yarong Hou, Ying Li, Qicheng Bei, Xin Li, Yong-Guan Zhu, Werner Liesack, Matthias C. Rillig, Jingjing Peng

“…Among 391 metagenome-assembled genomes (MAGs), the abundance of several Syntrophomonas and Methanocella MAGs increased concomitantly, suggesting that the NPs treatments stimulated the syntrophic oxidation of fatty acids. mRNA profiling further identified Methanosarcinaceae and Methanocellaceae to be the key players in the NPs-induced CH4 production. …”
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Transient lymphocyte count decrease correlates with oncolytic adenovirus efficacy in humans: mechanistic and biomarker findings from TUNIMO phase I trial by Tuomo Alanko, Akseli Hemminki, Víctor Cervera-Carrascón, Riikka Havunen, Kristian Taipale, Dafne C A Quixabeira, Jorma Sormunen, Katriina Peltola, Suvi Sorsa, Santeri A Pakola, Elise Jirovec, Lyna Haybout, Claudia Kistler, Tatiana V Kudling, Victor Arias, James H A Clubb, Mirte van der Heijden, Teijo Pellinen, Joao M Santos

“…Research presented in this study evaluated the immunological effects of TILT-123 in the TUNIMO trial by using biological samples collected from the patients during the study, with an objective to leverage the findings to develop possible biomarkers of response and gain insights into possible synergistic combination treatments.Methods 20 patients with advanced solid tumors were treated with TILT-123. …”
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Dairy cows' responses to 2 separation methods after 3 months of cow-calf contact by Anina Vogt, Susanne Waiblinger, Rupert Palme, Uta König von Borstel, Kerstin Barth

“…Furthermore, there was a transient increase in physiological distress markers and a short-lived retention of milk yield at initiation of treatments, indicating that both methods induced distress for the cows. …”
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First-trimester Doppler Ultrasound for Predicting Successful Management of Pregnancy with Recurrent Pregnancy Losses Due to Antiphospholipid Syndrome and Thrombophilia: A Cohort St... by Muhammad Adrianes Bachnas, Uki Retno Budihastuti, Eriana Melinawati, Nutria Widya Purna Anggraini, Robert Ridwan, Lini Astetri, Agung Sari Wijayanti, Atthahira Amalia Hafiizha, Muhammad Denny Gagah Pradana, Aliffudin Nur, Muhammad Alamsyah Azis, Wiryawan Permadi, Luthfi Rahman, Jimmy Yanuar Annas, Daniel Jonathan Mangapul Siagian, Neissya Nastiti Firmanto, Gilang Rizqy Perdana Aries Rohman, Muhammad Ilham Aldika Akbar

“…Background: Recurrent pregnancy loss (RPL) often stems from a hypercoagulable state that exacerbates conditions such as antiphospholipid syndrome (APS) and thrombophilia, leading to early placental issues. Although treatments such as low-molecular-weight heparin (LMWH) and low-dose aspirin (LDA) are used, outcomes vary. …”
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Mechanism of Action of <i>Fusarium oxysporum</i> CCS043 Utilizing Allelochemicals for Rhizosphere Colonization and Enhanced Infection Activity in <i>Rehmannia glutinosa</i> by Feiyue Yuan, Fuxiang Qiu, Jiawei Xie, Yongxi Fan, Bao Zhang, Tingting Zhang, Zhongyi Zhang, Li Gu, Mingjie Li

“…Meanwhile; it was found that among the effector-protein-coding genes; ChiC; VRDA; csn; and chitinase exhibited upregulated expression across all treatments. The expression patterns of these key genes were validated using qRT-PCR. …”
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Putative effects of moringa oil or its nano-emulsion on the growth, physiological responses, blood health, semen quality, and the sperm antioxidant-related genes in ram by Rehab F. S. A. Ismail, Wael A. Khalil, Sara I. Grawish, Karima Gh. M. Mahmoud, Sameh A. Abdelnour, Alaa M. A. Gad

“…Growth, physiological response, blood health, semen quality, and antioxidant genes in sperm were assessed. The MO and NMO treatments had no significant effect on growth indices (final body weight and weight gain ) and physiological response (rectal temperature, pulse, and respiration rates) (P > 0.05). …”
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Vaccination in Nile tilapia broodstock with whole cell vaccine and disease resistance in its fry against Aeromonas hydrophila by Sukenda Sukenda, Odang Carman, Rahman Rahman, Dendi Hidayatullah, Nurfitriani Siti Yumaidawati

“…This study used complete randomized design with two treatments and three replications. Antibody level was measured by using indirect enzyme-linked immunosorbent assay (ELISA) method in the broodstock, egg, and fry.  …”
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The Impact of Mixed Application of Modified Straw Biochar and Organic Fertilizer on Soil Water Retention and Fertility Maintenance in the Loess Hilly Dry Area by ZHANG Peizhen, LUO Juan, YAO Zonglu, CHANG Fangling, HUO Lili, ZHAO Lixin

“…In terms of soil water retention and nutrient conservation properties, under the treatments of mixed application of biochar and fertilizer, soil bulk density decreased with the increase of the biochar-to-fertilizer ratio, and soil porosity increased by 2.42%~4.07%. …”
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Crocin improves post-thaw quality, fertility-associated gene expression and fertilization potential of buffalo bull sperm by Amjad Riaz, Ghulam S. Khan, Muhammad Zahid Tahir, Muhammad Yasir Zahoor, Hifz-ul-Rahman Hifz-ul-Rahman

“…Tukey test was applied for multiple comparisons among treatments. Post-thaw evaluation revealed that 0.5 and 1mM crocin improved total motility, plasma membrane integrity, acrosome integrity, mitochondrial membrane potential, and viability, and one and 1.5mM crocin enhanced catalase activity and reduced lipid peroxidation compared to control (p<0.05). …”
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The hydraulic performance and clogging characteristics of a subsurface drip irrigation system operating for five years in the North China plain by Li Zaiyu, Mo Yan, Gao Hao, Gong Shihong, Zhang Yanqun, Li Guangyong, Wu Feng

“…To achieve a life of more than 20 years, additional acid/chlorine treatments, which supplement the existing system components and the current practice of flushing twice annually, are necessary.…”
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Morphological characterization and yield of pepper (Piper nigrum L.) types grown in Morogoro District, Tanzania by Abdul Jafari Shango, Ramadhani Omari Majubwa, Amon Petro Maerere

“…Methods The evaluation of pepper morphological characters was conducted following a randomized complete block design with three replications and four treatments (pepper types). Observations were recorded with respect to 28 characters (9 qualitative and 19 quantitative) which entail vegetative (8) and reproductive (20) traits. …”
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