Pregnant Women, a Potential Reservoir for Onchocerca volvulus? A Cross Sectional Study in Maridi County, South Sudan by Chiara Trevisan, Amber Hadermann, Stephen Raimon Jada, Raphael A. Abong, Yak Yak Bol, Joseph N. Siewe Fodjo, Katja Polman, Robert Colebunders

“…Pregnant women may be a parasite reservoir as they are not included in routine ivermectin (IVM) treatments due to unassessed drug safety. In our study we determined the proportion of pregnant women infected with Onchocerca volvulus and assessed the knowledge and practices on IVM use during pregnancy. …”
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Time to recovery of neonatal sepsis and its predictors in public hospitals of North Shoa Zone, Central Ethiopia by Befekadu Tesfaye Oyato, Teshome Ketema Sime, Tirunesh Debele, Husen Zakir Abasimel, Fikadu Tolesa Alemu, Samuel Boja Asfaw, Wuletaw Tadesse Mekonnin, Hana Israel Gesisa, Elleni Tesfaye Kebede

“…Prolonged recovery time of neonatal sepsis leads to hospitalization, increased cost of treatments, antimicrobial resistance, disseminated intravascular coagulation, respiratory failure, septic shock, brain lesions, renal failure, and cardiovascular dysfunction, and eventually death. …”
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Arctiin Protects Chondrocytes from Interleukin-1β-Induced Inflammation and Apoptosis by RNA Sequence In vivo and In vitro by Yong-Jia Song, Jia-Min Bao, Zeng-Qiao Zhang, Yun-Xiang Hai, Hao-Nan Wen, Tian-Jun Zhai, Wei Feng, Min Song

“…This highlights ARC’s therapeutic potential and its role in the development of treatments for OA.…”
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Enhancing ethical self-efficacy among dementia caregiver staff: A mixed-methods feasibility study of the care programme by Sigurd Lauridsen, Sofie Smedegaard Skov, Lucca-Mathilde Thorup, Marie-Eva Berg, Anna Paldam Folker, Peter Simonsen, Frederik Schou-Juul

“…Despite the increasing prevalence of dementia, effective treatments remain limited. High-quality care is critical, but it presents complex ethical challenges, including balancing autonomy with best interests, addressing the needs of individuals with dementia and their caregivers, and equitably allocating resources. …”
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Innovative Deep Learning Architecture for the Classification of Lung and Colon Cancer From Histopathology Images by Menatalla M. R. Said, Md. Sakib Bin Islam, Md. Shaheenur Islam Sumon, Semir Vranic, Rafif Mahmood Al Saady, Abdulrahman Alqahtani, Muhammad E. H. Chowdhury, Shona Pedersen

“…The health and well-being of patients are jeopardized in the absence of adequately trained histopathologists, potentially leading to misdiagnoses, unnecessary treatments, and tests, resulting in the inefficient utilization of healthcare resources. …”
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Identification of major hemorrhage in trauma patients in the prehospital setting: diagnostic accuracy and impact on outcome by Nigel R M Tai, Evangelia Kyrimi, Jared M Wohlgemut, Zane B Perkins, William Marsh, Michael Christian, Erhan Pisirir, Rebecca S Stoner, Thomas Hurst

“…Early identification of patients with major hemorrhage (MH) is important as treatments are time-critical. However, diagnosis can be difficult, even for expert clinicians. …”
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Impact of re-operation on progression-free survival in patients with recurrent GBM: Experience in a tertiary referral center. by Houssein Darwish, Tasnim Diab, Sarah Kawtharani, Mounir Barake, Bader Ali, Nagham Ramadan, Hiba Fadlallah, Jeannot Kekedjian, Marwan Najjar, Hazem I Assi

“…GBM is known for its aggressive nature and poor prognosis, with most patients experiencing tumor recurrence despite initial treatments. Some studies suggest a survival benefit from a second surgery, while others do not. …”
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Efficacy and Acceptability of a Mobile App for Monitoring the Clinical Status of Patients With Chronic Obstructive Pulmonary Disease Receiving Home Oxygen Therapy: Randomized Contr... by Anisbed Naranjo-Rojas, Luis Ángel Perula-de Torres, Freiser Eccehomo Cruz-Mosquera, Guillermo Molina-Recio

“…One of the primary treatments for COPD is oxygen therapy, which helps manage dyspnea and improve survival rates. …”
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Geographical Differences in the Safety and Efficacy of Tofacitinib Versus TNFi: A Post Hoc Analysis of ORAL Surveillance by Bogdan Batko, Slawomir Jeka, Piotr Wiland, Agnieszka Zielińska, Maria Stopińska-Polaszewska, Marcin Stajszczyk, Magdalena Kosydar-Piechna, Mary Jane Cadatal, Jose L. Rivas

“…Serious infections IRs were numerically higher in North America versus Poland across treatments. Venous thromboembolism/all-cause mortality IRs were generally comparable across regions. …”
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Incidence of opportunistic infections and its predictors among HIV/AIDS patients on antiretroviral therapy in Gondar University Comprehensive and Specialized Hospital, Ethiopia by Mequanente Dagnaw, Haileab Fekadu, Adhanom Gebre Egziabher, Tesfaye Yesfue, Meera Indracanti, Alemu Tebeje

“…Current and accurate information about the occurrence of opportunistic infections in HIV-infected adults is critical for developing more effective treatments and interventions. However, few studies have been conducted in Ethiopia on the prevalence of common opportunistic infections in HIV-infected adults. …”
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Effect of Sucrose as Carbon Source and Probiotic Administrations on Bacterial Population Dinamic and Water Quality in White Shrimp, Litopenaeus vannamei Culture by . Sukenda, P. Hadi, E. Harris

“…This study was performed to determine effect of sucrose and probiotic supplementation to shrimp culture pond on water quality profile and population dynamic on shrimp culture media.  The treatments were supplementation of sucrose as carbon source, probiotic, and sucrose + probiotic into 25 L culture medium containing white shrimp, Litopenaeus vannamei.  …”
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Exosomes and their distinct integrins transfer the characteristics of oxaliplatin- and 5-FU-resistant behaviors in colorectal cancer cells by Zeynab Vakili-Ghartavol, Hoda Deli, Amir Shadboorestan, Roxana Sahebnasagh, Elahe Motevaseli, Mohammad Hossein Ghahremani

“…Conclusion Our findings reveal that, despite discrepancies between cellular integrin patterns and cellular behaviors, the levels of exosomal ITGβ3, ITGαv, or ITGβ4 could serve as potential diagnostic and therapeutic markers for resistance to oxaliplatin and 5-FU in future cancer treatments.…”
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Trends and Gaps in Digital Precision Hypertension Management: Scoping Review by Namuun Clifford, Rachel Tunis, Adetimilehin Ariyo, Haoxiang Yu, Hyekyun Rhee, Kavita Radhakrishnan

“… BackgroundHypertension (HTN) is the leading cause of cardiovascular disease morbidity and mortality worldwide. Despite effective treatments, most people with HTN do not have their blood pressure under control. …”
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Insights into salinity effect on growth of the spotted scat (Scatophagus argus): Exploring the optimum salinity for its culture by Maoliang Su, Zhanquan Feng, Youling Zhong, Zhiyin Ye, Junbin Zhang

“…After a 12-week experimental period, the average body weight of S. argus juveniles was significantly different (p < 0.05) in six salinity treatments (5, 10, 15, 20, 25, and 30 ppt). Feed intake (FI) was increased with the enhancement of environmental salinity, and its highest value (1.51 ± 0.11) was found in 30 ppt group. …”
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Whole-cell vaccine of Streptococcus agalactiae in Oreochromis sp. with immersion method by , Sukenda, Trian Rizky Febriansyah, Sri Nuryati

“…Both vaccines have shown higher survival (60%) and RPS (40%) when challenged with pathogenic Streptococcus N14G isolates than other treatments. Based on RPS percentage observed, those vaccine were still not sufficiently effective to combat S. agalactiae infection.   …”
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Effects of home bleaching agents on hybrid ceramics: mechanical properties and color change by Waleed M. Hafny, Imam M. Ibrahim, Mohamed El-Demellawy, Hoda M. Abdel Sadek

“…This study provides comparative insights into the material responses to aesthetic treatments by assessing the effects of home bleaching agents on two hybrid ceramics: VITA ENAMIC® and Grandio Blocs. …”
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Embryonic heat conditioning induces paternal heredity of immunological cross- tolerance: coordinative role of CpG DNA methylation and miR-200a regulation by Padma Malini Ravi, Tatiana Kisliouk, Shelly Druyan, Amit Haron, Mark A. Cline, Elizabeth R. Gilbert, Noam Meiri

“…Male offspring were raised to maturity, and their sperm was analyzed for methylome patterns, revealing significant differences between treatments, particularly in immune and development related genes. …”
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Therapeutic potential of Chromolaena odorata, Vernonia amygdalina, and Cymbopogon citratus against pathogenic Bacteria by Udensi Justina Ugochi, Anyanwu Charles Obinna, Emedoh Andrew Emeka, Anyanwu Emilia Oluchi, Danladi Makeri, Pius Theophilus, Ezera Agwu

“…Abstract Antimicrobial resistance poses a global public health threat, compelling the search for alternative treatments, especially in resource-limited settings. …”
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A new approach to continuous monitoring of carbon use efficiency and biosynthesis in soil microbes from measurement of CO₂ and O₂ by K. E. Smart, D. O. Breecker, C. B. Blackwood, C. B. Blackwood, C. B. Blackwood, T. M. Gallagher

“…Extractions of microbial biomass carbon at the end of the experiments reveal minimal net increases in standing biomass across all amended treatments, suggesting that much of this newly produced biomass is likely converted to necromass as substrate availability declines, and this results in a net storage of new soil organic matter. …”
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Dietary rosemary oil with/without zymogen forte improves water quality, growth hormones, immune-physiological response, stress resilience, and health status of Chelon ramada grown... by Ashraf I. G. Elhetawy, Mohammed F. El Basuini, Ahmed I. A. Mansour, Shimaa A. Shahin, Amira A. Omar, Mohamed M. Zayed, Mohamed M. Abdel-Rahim

“…A 75-day rearing trial was conducted to evaluate fish growth, immune response, overall health, and water quality of Chelon ramada cultured in brackish GW and fed on a basal diet (BD) augmented with rosemary oil (RO) or RO + zymogen forte™ (ZF) as an anti-flatulent. Five treatments were administrated in triplicate: T1: fish-fed BD without additives (control group); T2: fish-fed BD + 0.5 g RO /kg diet; T3: fish-fed BD + 0.5 g RO and 1 g ZF /kg diet; T4: fish-fed BD + 1 g RO /kg diet; T5: fish-fed BD + 1 g RO and 1 g ZF /kg diet. …”
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