Interference of Celastrol with Cell Wall Synthesis and Biofilm Formation in <i>Staphylococcus epidermidis</i> by Leandro de León Guerra, Nayely Padilla Montaño, Laila Moujir

“…Its efficacy in disrupting the formation of biofilms and pre-formed biofilms suggests its potential as a therapeutic agent for infections caused by biofilm-forming <i>S. epidermidis</i> resistant to conventional treatments.…”
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A Mobile App–Based Gratitude Intervention’s Effect on Mental Well-Being in University Students: Randomized Controlled Trial by Chloë Fuller, Silvia Marin-Dragu, Ravishankar Subramani Iyer, Sandra Melanie Meier

“…Clinicians could look at incorporating gratitude apps with other mental health treatments or for those waitlisted as a cost-effective and minimally guided option for university students experiencing psychological distress.…”
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Optimizing in vitro spherulation cues in the fungal pathogen Coccidioides by Christina M. Homer, Elena Ochoa, Mark Voorhies, Anita Sil

“…Coccidioides can infect both immunocompetent and immunocompromised people and can cause a devastating disseminated infection, including meningitis, with 30% mortality despite all currently available treatments. In this work, we tackle one of the current largest technical barriers to studying the fungus Coccidioides: reliably growing its host form in vitro. …”
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Anaesthetic efficacy of intraligamentary injection compared to incisive nerve block using 3% mepivacaine hydrochloride: a randomized clinical trial by Suzan Salem, Islam Saad, Ramy Elmoazen, Ghada Amin Khalifa

“…Abstract Background In dentistry, local anesthetic is frequently used to manage pain throughout several phases of dental treatments, including tooth extraction. The study aimed to compare the effectiveness of two techniques for controlling pain during mandibular exodontia (tooth extraction), specifically focusing on the pain experienced during injection and extraction of mandibular anterior and premolars teeth. …”
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Effects of Functional Red Pine Seed Direct-Drinking Oil on Constipation and Intestinal Barrier Function in Mice by Jie Li, Haonan Zheng, Jiahui Liu, Jie Ding, Qingqi Guo, Na Zhang

“…However, many existing treatments are associated with side effects, necessitating the development of alternative approaches. …”
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Preliminary Exploration of Natural Polyphenols and/or Herbal Mix Replacing Sodium Nitrate to Improve the Storage Quality of Pork Sausage by Angeliki-Niki Kaloudi, Agori Karageorgou, Michael Goliomytis, Panagiotis Simitzis

“…Values for the lightness (L), shear force and cooking loss were similar among the experimental treatments (<i>p</i> > 0.05). On the other hand, pH values were greater in the SN and NM groups than in the other groups (<i>p</i> < 0.05). …”
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Failure of Urological Implants in Spinal Cord Injury Patients due to Infection, Malfunction, and Implants Becoming Obsolete due to Medical Progress and Age-Related Changes in Human... by Subramanian Vaidyanathan, Bakul Soni, Gurpreet Singh, Peter Hughes, Fahed Selmi, Paul Mansour

“…Some surgical procedures such as dorsal rhizotomy are irreversible. Alternative treatments such as intermittent catheterisations may be less damaging than bladder stimulator in the long term.…”
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Evaluating catastrophic health expenditures among patients with long bone fractures in Ghana's major teaching hospitals: a hospital-based analysis by Alexis D. B. Buunaaim, Michel Adurayi Amenah, Dominic Konadu-Yeboah, Richard Baidoo, Amgbo Asare, Wilfred Larbi Addo, Claude Martin

“…Policy interventions aimed at expanding NHIS coverage, reducing OOP payments for high-cost treatments, and addressing geographic inequities are urgently needed to improve financial protection for patients with long bone fractures in Ghana. …”
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Diurnal variation in brain injury after cardiac arrest and cardiopulmonary resuscitation by Fei Peng, Fei Wang, Bowen Gao, Ping Sun

“…BackgroundAlthough the circadian rhythm is known to influence several neurological diseases and response to treatments, its potential impact on brain injury following cardiac arrest and cardiopulmonary resuscitation (CA/CPR) remains unclear.MethodsWe performed a retrospective observational study on out-of-hospital cardiac arrest (OHCA) cases that presented to the emergency department of our hospital between September 2022 and August 2024. …”
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“I’m living in a ‘no’ world now…”- A qualitative study of the widespread impact of living with chronic breathlessness, and experiences of identification and assessment of this symp... by Helene L. Elliott-Button, Miriam J. Johnson, Ann Hutchinson, David C. Currow, Joseph Clark

“…Management is limited; few are offered evidence-based treatments (e.g., handheld fan) and patients find their own strategies. (4) Need for education and information. …”
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The relationship between cholesterol levels and thyroid eye disease by Caroline Cardo, Roberto Bernardo Santos, Ana Beatriz Pinotti Pedro Miklos, Sabrina Barbosa Jaconis, João Hamilton Romaldini, Danilo Villagelin

“…Methods: Data were collected from GD patients treated with methimazole between 1999 and 2021, excluding those receiving other treatments. Laboratory results and information on smoking habits, statin use and medications affecting lipid profiles during the euthyroid state were analyzed. …”
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Automated electronic health record-based screening for Fabry disease in unexplained left ventricular hypertrophy (FAPREV-HCM) by Christoph Wanner, Peter Nordbeck, Lora Lorenz, Nurcan Üçeyler, Claudia Sommer, Kolja Lau, Victoria Sokalski, Georg Fette

“…Early diagnosis of FD is crucial due to available treatments, but its rarity and diverse symptoms complicate identification. …”
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Enhancing cotton irrigation with distributional actor–critic reinforcement learning by Yi Chen, Meiwei Lin, Zhuo Yu, Weihong Sun, Weiguo Fu, Liang He

“…We used soil and plant state indicators from 5 experimental groups with varying irrigation treatments to calibrate and validate the DSSAT model. …”
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A plant endophytic bacterium Burkholderia seminalis strain 869T2 increases plant growth under salt stress by affecting several phytohormone response pathways by Hau-Hsuan Hwang, Yu-Ting Huang, Pei-Ru Chien, Fan-Chen Huang, Chih-Lin Wu, Liang-Yu Chen, Shih-Hsun Walter Hung, I-Chun Pan, Chieh-Chen Huang

“…Both transcriptome analysis and quantitative real-time PCR results showed that expression levels of genes related to phytohormone signal transduction pathways, including auxin, gibberellin, cytokinin, and abscisic acid were altered in Arabidopsis plants after inoculated with the strain 869T2 under salt stress, in comparison to the mock-inoculated control with salt treatments. Furthermore, the accumulation levels of hydrogen peroxide (H2O2), electrolyte leakage (EL), and malondialdehyde (MDA) were lower in the 869T2-inoculated Arabidopsis and pak choi plants than in control plants under salt and drought stresses. …”
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Copper Resistance in <i>Pseudomonas syringae</i> pv. <i>actinidiae</i> Strains from the Prefecture of Pella, Northern Greece, and a Comparison of the Effectiveness of Several Comme... by Thomas Thomidis, Marianthi G. Pagoulatou, Eleftherios Alexandridis, Evaggelia Mpalantinaki, Dimitrios E. Goumas

“…<i>actinidiae</i> (<i>Psa</i>), a significant pathogen threatening kiwifruit cultivation globally. Copper-based treatments, widely used for their broad-spectrum bactericidal properties, have become less effective over time due to the emergence of copper-resistant strains. …”
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Skin Microbiota: Mediator of Interactions Between Metabolic Disorders and Cutaneous Health and Disease by Magdalini Kreouzi, Nikolaos Theodorakis, Maria Nikolaou, Georgios Feretzakis, Athanasios Anastasiou, Konstantinos Kalodanis, Aikaterini Sakagianni

“…Clinical trials have demonstrated significant reductions in inflammatory lesions and improved quality-of-life metrics in patients receiving these microbiota-targeted treatments. This review synthesizes current evidence on the bidirectional interplay between metabolic disorders and skin microbiota, highlighting therapeutic implications and future directions. …”
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Comparison of Efficacy and Safety of Lispro and Aspart Evaluated by Continuous Glucose Monitoring System in Patients with Newly Diagnosed Type 2 Diabetes by Bing-li Liu, Guo-ping Yin, Feng-fei Li, Yun Hu, Jin-dan Wu, Mao-yuan Chen, Lei Ye, Xiao-fei Su, Jian-hua Ma

“…They all received CSII and metformin therapy. Treatments were maintained for 2-3 weeks after the glycaemic target was reached. …”
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Production performance and water quality of Caulerpa lentillifera with fermented fruit vegetable fertilizer by Eddy Supriyono, Chrisliana Chrisliana, Yuni Puji Hastuti, Kadek Lila Antara, Yong Ee Ling, Wildan Nurussalam

“…The experimental design used was a completely randomized design with three replications for four different doses of FVF fertilizer treatments, namely 0, 0.05, 0.1, and 0.2 µl/L. This study used an initial weight of 500 g which was reared in a concrete tank with a capacity of 1000 L for 30 days growth period. …”
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Ten-year trends in clinical characteristics and outcome of children hospitalized with severe wasting or nutritional edema in Malawi (2011-2021): Declining admissions but worsened c... by Mphatso Nancy Chisala, Celine Bourdon, Emmanuel Chimwezi, Allison I Daniel, Chikondi Makwinja, Dominic Wang, Linnea Weise, Isabel Potani, Emmie Mbale, Robert J H Bandsma, Wieger P Voskuijl

“…Longitudinal data from major NRUs can identify shifts in clinical profiles or outcomes, and this information can be leveraged to promote earlier care-seeking, improved risk stratification, and implementation of more patient-centered treatments.…”
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Diagnostic efficacy and necessity of 18F-FDG PET/CT in fever of unknown origin: insights from a retrospective cohort study by Xiaoman Yu, Shuang Wang, Na Du, Hongguang Zhao, Haiying Chen

“…All patients received a final clinical diagnosis after various treatments, which helped determine the diagnostic relevance of identified lesions using 18F-FDG PET/CT. …”
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