miR-125b differentially impacts mineralization in dexamethasone and calcium-treated human mesenchymal stem cells by Virginie Joris, Elizabeth R. Balmayor, Martijn van Griensven

“…While these targets remained identical in both treatments, their modulation after transfection was different. …”
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Serum microRNAs as Diagnostic Markers in Polycystic Ovary Syndrome: A Narrative Review by K Lavanya, N Palaniappan, VM Vinodhini, Santhi Silambanan

“…Therefore, a variety of medications that are either agonists or antagonists of microRNAs may be useful in initiating tailored treatments. The profiles of microRNAs differ depending on the tissue from which they originate. …”
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Rituximab-associated adverse events in nephrotic syndrome: A systematic review and meta-analysis by Zixian Yu, Meijin Huang, Yunlong Qin, Xiayin Li, Yueru Zhao, Yuwei Wang, Yumeng Zhang, Anjing Wang, Mei Han, Jin Zhao, Shiren Sun

“…Conclusion: RTX reveals great potential in terms of safety compared to non-RTX treatments due to the relatively few AEs in our results. …”
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BCI-Based Rehabilitation on the Stroke in Sequela Stage by Yangyang Miao, Shugeng Chen, Xinru Zhang, Jing Jin, Ren Xu, Ian Daly, Jie Jia, Xingyu Wang, Andrzej Cichocki, Tzyy-Ping Jung

“…This study provides a more autonomous approach than traditional treatments used in stroke rehabilitation.…”
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The economic burden of atopic dermatitis in Romania: a broad perspective by Alin Codruț Nicolescu, Stefan Strilciuc, Stefan Strilciuc, Rozalina Lăpădatu, Diana-Alecsandra Grad, Cristian Vlădescu, Cristian Vlădescu, Rodica Olteanu

“…This study evaluated the economic burden of AD in Romania, considering both direct and indirect costs.Materials and methodsA cost of illness study, conducted from a broad perspective, considering 2022 as a reference, using top-down and bottom-up approaches and retrospective and prospective data sources was used to assess direct medical costs (treatments, medical services, hospitalizations), direct non-medical costs (associated costs due to transportation, accommodation), and indirect costs (productivity losses) across four costing scenarios.ResultsIn 2022, the total cost of atopic dermatitis in Romania was €29,810,077.2 for adult patients and €133,635,535.2 for pediatric patients, based on a prevalence-based approach, and €5,529,867.8 for adults and €53,175,049.1 for pediatric AD patients when using an incidence-based approach. …”
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Analysis of Circulating MicroRNAs In Vivo following Administration of Dexamethasone and Adrenocorticotropin by Ivan Igaz, Gábor Nyírő, Zoltán Nagy, Henriett Butz, Zsolt Nagy, Pál Perge, Peter Sahin, Miklós Tóth, Károly Rácz, Peter Igaz, Attila Patócs

“…Only circulating hsa-miR-27a proved to be significantly modulated in vivo by hormonal treatments: its expression was upregulated by dexamethasone whereas it was suppressed by adrenocorticotropin. …”
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Investigating the causal pathways among psychopathological variables, cognitive impairment, and real-life functioning in people with schizophrenia by Luigi Giuliani, Francesco Sanmarchi, Armida Mucci, Paola Rucci, Edoardo Caporusso, Paola Bucci, Giulia M. Giordano, Mario Amore, Paola Rocca, Alessandro Rossi, Alessandro Bertolino, Silvana Galderisi, Mario Maj

“…The impact of everyday life and interpersonal functioning on the clinical presentation of schizophrenia suggests that integrated and personalized treatments, promoting relevant skills to improve these functional outcomes, may have a beneficial impact on clinical outcomes.…”
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Effectiveness of Space Maintainers in Pediatric Patients: A Systematic Review and Meta-Analysis by MDolores Casaña-Ruiz, Juan Ignacio Aura-Tormos, Laura Marques-Martinez, Esther Garcia-Miralles, Marcelino Perez-Bermejo

“…<b>Conclusions:</b> Space maintainers help prevent the migration of adjacent teeth and the need for more invasive orthodontic treatments in the future. Additionally, they contribute to adequate masticatory function and speech development.…”
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Effect of 2,4-Thiazolidinedione on Limousin Cattle Growth and on Muscle and Adipose Tissue Metabolism by M. Arévalo-Turrubiarte, L. González-Dávalos, A. Yabuta, J. D. Garza, J. L. Dávalos, O. Mora, A. Shimada

“…Seventeen Limousin bulls (18 month-old; 350 kg body weight (BW)) were assigned into 2 treatments: control and 2,4-TZD (8 mg/70 kg BW) and were fed until bulls reached 500 kg BW. …”
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Toxicity test of compound essential oil nanoemulsion on fall armyworm (Spodoptera frugiperda J.E. Smith) eggs by Nurnina Nonci, Rita Noveriza, Araz Meilin, Melati Melati, Ifa Manzila, Arlyna B. Pustika, Haliatur Rahma, Erwin Najamuddin, Amran Muis

“…The results show that, compared with the other treatments, the dose of 13.6 ml/L CEoNE is more effective against 3-d-old egg masses, which indicates that CEoNE has an ovicidal effect on S. frugiperda.…”
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Characterization and genomic insights into bacteriophages Kpph1 and Kpph9 against hypervirulent carbapenem-resistant Klebsiella pneumoniae by Ye Huang, Yuan Huang, Zhiping Wu, Ziyue Fan, Fanglin Zheng, Yang Liu, Xinping Xu

“…Bacteriophages, also known as phages, are viruses that specifically infect bacteria; thus, phage-based therapies offer promising alternatives to antibiotic treatments targeting Hv-CRKp infections. In this study, two isolated bacteriophages, Kpph1 and Kpph9, were characterized for their specificity against the Hv-CRKp K. pneumoniae NUHL30457 strain that possesses a K2 capsule serotype. …”
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Cancer Stem Cells from Tumor Cell Lines Activate the DNA Damage Response Pathway after Ionizing Radiation More Efficiently Than Noncancer Stem Cells by Heriberto Abraham Valencia-González, Graciela Ruíz, Elizabeth Ortiz-Sánchez, Alejandro García-Carrancá

“…Understanding the DNA damage response pathway may provide therapeutic targets to sensitize CSC to cytotoxic therapies to improve current cancer treatments.…”
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Peach palm residue compost as substrate for Bactris gasipaes self-sustaining seedlings production by Francielen Paola de Sá, Andreza Cerioni Belniaki, Maristela Panobianco, Mônica Moreno Gabira, Dagma Kratz, Edson Alves de Lima, Ivar Wendling, Washington Luiz Esteves Magalhães

“…Compost samples were characterized chemically and physically. The treatments consisted of different proportions of compost and soil (medium commonly used in <em>B. gasipaes</em> seedling nurseries), to make five growth media (v:v composted peach palm:soil): T1 - 100: 0; T2 - 75:25; T3 - 50:50; T4 - 25:75 and T5- 0: 100. …”
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Seaweed Fly Larvae Cultivated on Macroalgae Side Streams: A Novel Marine Protein and Omega-3 Source for Rainbow Trout by Niklas Warwas, Emma L. Berdan, Xintian Xie, Elisabeth Jönsson, Jonathan A. C. Roques, Darragh Doyle, Markus Langeland, James Hinchcliffe, Henrik Pavia, Kristina Sundell

“…No difference in intestinal health parameters was noted between the insect diets and the control diet, indicating good intestinal health across all treatments. However, changes in electrogenic intestinal transport were observed between the SWFL and BSFL diets, illustrating the heterogeneous effect of different insect products. …”
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Arsenic Uptake in Durum Wheat (<i>Triticum durum</i> Desf.) as Influenced by Soil Tillage Practices and Fertilization Sources in Mediterranean Environment by Ilenia Bravo, Mariam Atait, Ilenia Colamatteo, Roberto Mancinelli, Mohamed Allam, Patrizia Papetti, Emanuele Radicetti

“…The current study was carried out through a 7-year experiment with the aim of evaluating the As uptake by different parts of the durum wheat plant. The experimental treatments include the following: (i) three soil tillage practices (plowing, subsoiling, and spading) and (ii) two fertilization methods (mineral and organic). …”
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Growth and immune response of Litopenaeus vannamei fed on β-(1, 3) glucan and poly-β hydroxybutyrate by , Sarmin, Muhammad Agus Suprayudi, Dedi Jusadi, Julie Ekasari

“…Shrimp juvenile at an initial body weight of 2.06±0.03 g was randomly distributed into 12 units of aquaria at a density of 20 shrimps/tank and reared for 42 days. The treatments applied in this study were control (without feed additives), 1.5 g/kg BG, 10 g/kg PHB and 1,5 g/kg BG+10 g/kg PHB. …”
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C3AR1 as a target for preeclampsia: from bioinformatics and network pharmacology to experimental validation by Yongfeng Hu, Shaoqiang Li, Yunhui Hong, Dongxian Peng

“…It is crucial for cellular functions and inflammation, with future studies aiming to leverage this for novel preeclampsia treatments. Clinical trial Not applicable.…”
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Impact of the Timing of Enzyme Replacement Therapy Initiation and Cognitive Impairment Status on Outcomes for Patients with Mucopolysaccharidosis II (MPS II) in the United States:... by Karen S. Yee, David Alexanderian, Yidie Feng, Xiaowei Ren, Bernd Schweikert, Olulade Ayodele

“…Patient care could be improved with early cognitive assessments and the development of treatments that address cognitive decline.…”
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Bio-protective solutions for carrot spoilage: exploring the antifungal properties of ginger, garlic, onion, and Moringa by Eugenia Njoku, Florence Mbaoji, Justus Nweze, Bonaventure Echezona, Kayode Baiyeri

“…Ginger showed the highest antifungal effectiveness, with minimal inhibitory concentrations ranging from 31.25 mg/ml to 250 mg/ml, particularly against A. niger and A. fumigatus, demonstrating higher antifungal activity compared to other treatments. Garlic consistently exhibited an MIC of 250 mg/ml against all test fungi. …”
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Use of Minimal Residual Disease Status to Reduce Uncertainty in Estimating Long-term Survival Outcomes for Newly Diagnosed Multiple Myeloma Patients by Naomi van Hest, Peter Morten, Keith Stubbs, Nicola Trevor

“…**Background:** Demonstrating the cost-effectiveness of new treatments for multiple myeloma (MM) often relies on the extrapolation of overall survival (OS) trial data. …”
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