Production of novel theranostic nano-vector based on superparamagnetic iron oxide nanoparticles/miR-497 targeting colorectal cancer by Asmaa M. Elfiky, May M. Eid, May El-Manawaty, Zeinab A. Elshahid, Elham Mohamed Youssef, Khaled Mahmoud

“…Consequently, the targeting miR-497/CTLA4 axis is a potential immunotherapy treatment strategy for CRC.…”
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Regulation of Murine Ovarian Epithelial Carcinoma by Vaccination against the Cytoplasmic Domain of Anti-Müllerian Hormone Receptor II by Cagri Sakalar, Suparna Mazumder, Justin M. Johnson, Cengiz Z. Altuntas, Ritika Jaini, Robert Aguilar, Sathyamangla V. Naga Prasad, Denise C. Connolly, Vincent K. Tuohy

“…We conclude that AMHR2-CD vaccination provides effective immunotherapy of EOC with relatively benign autoimmune complications.…”
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Patients outcomes in lung adenocarcinoma transforming to small-cell lung cancer after tyrosine kinase inhibitor therapy by Shuai Wang, Yongsen Wang, Xuan Wu, Li Yang, Xiaoju Zhang

“…Conclusion Transformed SCLC exhibited poor response to primary SCLC classic chemotherapy and immunotherapy. It carries a worse prognosis. Exploring novel therapeutic strategies for transformed SCLC is imperative.…”
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Digestive cancers: mechanisms, therapeutics and management by Tianzuo Zhan, Johannes Betge, Nadine Schulte, Lena Dreikhausen, Michael Hirth, Moying Li, Philip Weidner, Antonia Leipertz, Andreas Teufel, Matthias P. Ebert

“…We comprehensively describe the current stage-dependent pharmacological management of these malignancies, including chemo-, targeted, and immunotherapy. For each cancer entity, we provide an overview of recent therapeutic advancements and research progress. …”
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Multi-omic and machine learning analysis of mitochondrial RNA modification genes in lung adenocarcinoma for prognostic and therapeutic implications by Xiao Zhang, Jiatao Liu, Yaolin Cao, Wei Wang, Haoran Lin, Yue Yu

“…Additionally, MRMS is associated with immunotherapy-related features, suggesting its potential in predicting treatment response. …”
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OMP38 of Carbapenem‐Resistant Acinetobacter Baumannii‐Mediated mtDNA Release Activates the cGAS‐STING Signaling to Induce Inflammatory Response by Yang Yang, Yuanyuan Zeng, Jianjie Zhu, Jianjun Li, Lei Gu, Lin Wei, Zeyi Liu, Jian‐an Huang

“…Abstract Carbapenem‐resistant Acinetobacter baumannii (CRAB) has become a major threat in the treatment of bacterial infection, and immunotherapy in a non‐antibiotic‐dependent manner is an effective way to overcome CRAB infection. …”
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Harnessing nanotechnology for cancer treatment by Jiajun Zhu, Jiajun Zhu, HaeJu Lee, HaeJu Lee, Ruotong Huang, Ruotong Huang, Jianming Zhou, Jingjun Zhang, Xiaoyi Yang, Wenhan Zhou, Wangqing Jiang, Shuying Chen

“…Furthermore, nanotechnology-based therapeutic strategies, including photothermal therapy, gene therapy and immunotherapy are offering novel ways to combat cancer by selectively targeting tumor cells and enhancing the immune response. …”
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Influence of In Vitro IL-2 or IL-15 Alone or in Combination with Hsp-70-Derived 14-mer Peptide (TKD) on the Expression of NK Cell Activatory and Inhibitory Receptors by Ilona Hromadnikova, Petra Pirkova, Lucie Sedlackova

“…NK cells represent a potential tool for adoptive immunotherapy against tumors. Membrane-bound Hsp70 acts as a tumor-specific marker enhancing NK cell activity. …”
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A Unique Case of Mantle Cell Lymphoma Masquerading as a Cecal Mass by Sarahi Herrera-Gonzalez, Dema Shamoon, Tingliang Shen, Simon Badin, Yatinder Bains

“…Treatment involves conventional chemo-immunotherapy consisting of R CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone) or RB (rituximab and bendamustine), with the latter being better tolerated and associated with longer progression-free survival. …”
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Bone marrow immune cells and drug resistance in acute myeloid leukemia by Miao Zhang, Miao Zhang, You Yang, You Yang, Jing Liu, Jing Liu, Ling Guo, Ling Guo, Qulian Guo, Qulian Guo, Wenjun Liu, Wenjun Liu

“…This article reviews the research progress on the relationship between immune cells in the marrow microenvironment and chemoresistance in AML, aiming to provide new ideas for the immunotherapy of AML.…”
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What are the lived healthcare experiences of patients with primary sclerosing cholangitis? A community-based qualitative interview study by Sheila Greenfield, Gideon Hirschfield, Jayne Parry, Katherine Arndtz, Madeline Cameron

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Detection of The TNFSF Members BAFF, APRIL, TWEAK and Their Receptors in Normal Kidney and Renal Cell Carcinomas by Vassiliki Pelekanou, George Notas, Katerina Theodoropoulou, Marilena Kampa, Dimitrios Takos, Vassilia-Ismini Alexaki, Jelena Radojicic, Frank Sofras, Andreas Tsapis, Efstathios N. Stathopoulos, Elias Castanas

“…In advanced renal cell carcinoma (RCC), surgery combined with systemic chemotherapy and immunotherapy have had limited effectiveness. Therapeutic modalities targeting VEGF, PDGF, and c-kit using tyrosine kinase inhibitors and m-TOR using specific biologic factors are in development. …”
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B Lymphocyte—A Prognostic Indicator in Post‐Acute Pancreatitis Diabetes Mellitus by Xiaoyan Lin, Xiaoling Li, Junsheng Wang, Huiheng Liu

“…This would help clarify the pathogenesis of PPDM‐A at the cellular level and potentially provide new strategies for immunotherapy and even disease prevention. [Correction added on 24 January 2025, after first online publication: the third subtitle in Abstract section has been changed to ‘Results’.]…”
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YTHDF1 Regulates RELA m6A Modification and Activates the NF‐Kappa B Signaling Pathway to Promote the Mechanism of Gastric Cancer by Yangyuan Huang, Shihao Liang, Liping Li, Qingyu Zeng, Bin Li

“…Molecular targeted therapy and immunotherapy are progressing rapidly. It is very important to explore the pathogenesis pathways of GC and provide strong support for its treatment. …”
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Autologous haematopoiesis stem cell transplantation (AHSCT) for treatment-refractory autoimmune diseases in children by Jasmin Beate Kuemmerle-Deschner, Susanne Benseler, Joerg C Henes, Özlem Satirer, Michaela Döring, Till Lesk

“…All patients are in clinical remission, only four require ongoing immunotherapy. Safety: Three experienced infections, including HHV6, Candida and Ralstonia sepsis; one developed a systemic inflammatory response syndrome; two new onset secondary autoimmune diseases including autoimmune haemolytic anaemia, Graves’ disease and one was found to have a breast fibroadenoma. …”
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Efficacy of high-dose steroids versus low-dose steroids in the treatment of immune checkpoint inhibitor-associated myocarditis: a case series and systematic review by Xiuyue Man, Hong Wang, Chen Chen, Xiaofeng Cong, Lemeng Sun, Xueru Sun, Chen Chen, Jing Zhang, Lei Yang

“…BackgroundImmune checkpoint inhibitor-associated myocarditis (ICI-M) is a rare yet potentially fatal complication of immunotherapy, with no standardized treatment protocol due to limited data. …”
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Total HLA Class I Antigen Loss with the Downregulation of Antigen-Processing Machinery Components in Two Newly Established Sarcomatoid Hepatocellular Carcinoma Cell Lines by Wei-Yi Lei, Shih-Chieh Hsiung, Shao-Hsuan Wen, Chin-Hsuan Hsieh, Chien-Lin Chen, Christopher Glenn Wallace, Chien-Chung Chang, Shuen-Kuei Liao

“…These findings may have implications for a proper design of T cell immunotherapy for the treatment of sHCC patients.…”
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PRDX2 induces tumor immune evasion by modulating the HDAC3-Galectin-9 axis in lung adenocarcinoma cells by Yunjia Dong, Anqi Cheng, Jiawei Zhou, Jianqiang Guo, Yafeng Liu, Xuan Li, Maoqian Chen, Dong Hu, Jing Wu

“…Conclusions This study reveals the role of the PRDX2/HDAC3/Galectin-9 axis in LUAD immune escape and indicates Galectin-9 as a promising target for immunotherapy.…”
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IL-6-Inducing Peptide Prediction Based on 3D Structure and Graph Neural Network by Ruifen Cao, Qiangsheng Li, Pijing Wei, Yun Ding, Yannan Bin, Chunhou Zheng

“…IL-6-inducing peptides are critical for the development of immunotherapy and diagnostic biomarkers for some diseases. …”
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Construction of cuproptosis-related genes risk model predicts the prognosis of Uterine Corpus Endometrial Carcinoma by Yanfang Huang, Guoxian Luo, Xiujie Sheng, Jianqi Li

“…The identified signature of CDKN2A, GLS, and PPAT demonstrates significant predictive value for UCEC prognosis, suggesting their potential as therapeutic targets, including their application in immunotherapy strategies.…”
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