Combination Immunosuppressive Therapy in Primary Autoimmune Inner Ear Disease in Pregnancy by Saikrishna Ananthapadmanabhan, Joe Jabbour, David Brown, Vanaja Sivapathasingam

“…This can be achieved using steroids, immunomodulators, plasmapheresis, intravenous immunoglobulin, or biologic agents. …”
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Somatostatin in inflammatory bowel disease by J. D. Van Bergeijk, J. H. P. Wilson

“…Intestinal inflammation is controlled by various immunomodulating cells, interacting by molecular mediators. …”
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Pan-Cancer Analysis of the Cuproptosis-Related Gene DLD by Jiahui Lin, Guowei Wang, Sha Cheng, Yanan Hu, Huan Li, Wanjiang Feng, Xiaoming Liu, Canxia Xu

“…Significant correlations were also observed between DLD expression and immunomodulators, immune checkpoints, TMB, and MSI in various cancers. …”
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Severe Symptomatic Primary CMV Infection in Inflammatory Bowel Disease Patients with Low Population Seroprevalence by Catherine Rowan, Ciaran Judge, Mary D. Cannon, Garret Cullen, Hugh E. Mulcahy, Elizabeth Ryan, Cillian F. De Gascun, Glen A. Doherty

“…All eight patients were receiving a thiopurine immunomodulator. Median duration of IM use was 144 weeks (range 7–720 weeks). …”
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Signal Factors Secreted by 2D and Spheroid Mesenchymal Stem Cells and by Cocultures of Mesenchymal Stem Cells Derived Microvesicles and Retinal Photoreceptor Neurons by Lili Xie, Mao Mao, Liang Zhou, Lusi Zhang, Bing Jiang

“…Finally, to test if enhanced expression of these factors reflects altered immunomodulating activities, we assessed the effect of 2D-MSC-MVs and 3D-MSC-MVs on CD14+ cell chemoattraction. …”
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The Continental Divide: Anti-TNF Use in Pediatric IBD Is Different in North America Compared to Other Parts of the World by Peter C. Church, Jeffrey Hyams, Frank Ruemmele, Lissy de Ridder, Dan Turner, Anne M. Griffiths

“…North Americans more often continued immunomodulator indefinitely and less often adhered to standard infliximab induction dosing. …”
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Presence of Autoimmune Antibody in Chikungunya Infection by Wirach Maek-a-nantawat, Udomsak Silachamroon

“…The symptoms can mimic autoimmune polymyositis disease, and the condition requires close monitoring before deciding to embark upon prolonged specific treatment with immunomodulators.…”
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A Novel Green Synthesis of Thalidomide and Analogs by Ellis Benjamin, Yousef M. Hijji

“…Thalidomide and its derivatives are currently under investigation for their antiangiogenic, immunomodulative, and anticancer properties. Current methods used to synthesize these compounds involve multiple steps and extensive workup procedures. …”
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Complete Remission of Methotrexate-Related Epstein-Barr-Virus-Associated Hodgkin-Like Lymphoma following Withdrawal of MTX Coupled with Clarithromycin Administration by Nobuo Takemori, Hiroyuki Kaneko, Masaya Nakamura, Masaru Kojima

“…In particular, an immunomodulative effect of CAM might have been involved in achieving complete remission.…”
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The Frequency of Clinic Visits Was Not Associated with Medication Adherence or Outcome in Children with Inflammatory Bowel Diseases by Cheryl Kluthe, Jenkin Tsui, Donald Spady, Matthew Carroll, Eytan Wine, Hien Quoc Huynh

“…Almost all patients on infliximab infusions received them “within window.” Immunomodulator median adherence rate was 88%. 5-ASA adherence was 82%. …”
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Mother-fetus immunogenetic dialogue as a factor of progeny immune system development by L. A. Gerlinskaya, A. V. Varlachev, G. I. Krotov, G. V. Kontsevaya, M. P. Moshkin

“…Since breast milk contains large amounts of various immunoactive components, including proteins, cytokines, hormones, immunoglobulins, exosomes containing micro-RNA, and viable immune cells, the immunomodulating effects of breast milk persist even after elimination of maternal immunoglobulins from the blood of the offspring, up to maturation. …”
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The Mushroom Agaricus blazei Murill Elicits Medicinal Effects on Tumor, Infection, Allergy, and Inflammation through Its Modulation of Innate Immunity and Amelioration of Th1/Th2 I... by Geir Hetland, Egil Johnson, Torstein Lyberg, Gunnar Kvalheim

“…Agaricus blazei M is rich in the immunomodulating polysaccharides, β-glucans, and has been shown to have antitumor, anti-infection, and antiallergic/-asthmatic properties in mouse models, in addition to anti-inflammatory effects in inflammatory bowel disease patients. …”
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Babesiosis with low parasitemia as a cause of secondary hemophagocytic lymphohistiocytosis in a previously healthy adult by Max W. Jacobs, Joseph M. Rocco, Lisa K. Andersen, Thomas E. Robertson

“…Increasing awareness to improve time to diagnosis is vital for treating both babesiosis and sHLH, while future studies should investigate the role for immunomodulator therapy in this setting.…”
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Predicting, Treating and Preventing Postoperative Recurrence of Crohn’s Disease: The State of the Field by Anna M Borowiec, Richard N Fedorak

“…Furthermore, the postoperative prophylaxis profiles of available Crohn’s disease therapeutic agents such as 5-aminosalicylates, immunomodulators, steroids and probiotics have been disappointing. …”
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Spondyloarthritis and Risk of Malignancy: A Narrative Review on a Still Controversial Issue by Ennio Giulio Favalli, Francesco Grossi, Alberto Batticciotto, Matteo Filippini, Simone Parisi, Ombretta Viapiana, Paolo Gisondi, Paolo Dapavo, Lorenzo Dagna, Filippo De Braud

“…Malignancy may be a major comorbidity in subjects with spondyloarthritis (SpA) as the result of multifactorial mechanisms, from disease pathogenesis to the iatrogenic effect of immunomodulating drugs. Several recommendations for screening and management of cancer risk have been developed in recent years with the aim of improving the different outcomes in these patients. …”
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Systemic Levamisole-Induced Vasculitis in a Cocaine User without Cutaneous Findings: A Consideration in Diagnosis by Gillian G. Baptiste, Anastasia-Stefania Alexopoulos, Tahsin Masud, Joanna M. Bonsall

“…Levamisole is a known immunomodulating agent frequently used as a cutting agent in cocaine consumed in the United States today. …”
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Study of Traditional Uses, Extraction Procedures, Phytochemical Constituents, and Pharmacological Properties of Tiliacora triandra by Gitishree Das, Sushanto Gouda, Rout George Kerry, Hernán Cortes, María L. Del Prado-Audelo, Gerardo Leyva-Gómez, Patrick Valere Tsouh Fokou, Erick P. Gutiérrez-Grijalva, J. Basilio Heredia, Han-Seung Shin, Jayanta Kumar Patra

“…The leaves and root extracts are used to treat gastrointestinal diseases, hypertension, diabetes, skin diseases, and malaria as an antipyretic, detoxification agent, anti-inflammatory, anticancer, and immunomodulator. Bioactive compounds contained in T. triandra include phenolic compounds, alkaloids, flavonoids, terpenoids, fatty acids, essential amino acids, peptides, carbohydrates, vitamins, and nucleic acid precursors. …”
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Mesenchymal Stromal Cells Suppress Hippocampal Neuron Autophagy Stress Induced by Hypoxic-Ischemic Brain Damage: The Possible Role of Endogenous IL-6 Secretion by Miao Yang, Wuqing Sun, Lu Xiao, Mulan He, Yan Gu, Ting Yang, Jie Chen, Xiaohua Liang

“…Increasing evidence has revealed that mesenchymal stromal cell (MSC) transplantation alleviates hypoxic-ischemic brain damage (HIBD) induced neurological impairments via immunomodulating astrocyte antiapoptosis effects. However, it remains unclear whether MSCs regulate neuron autophagy following HIBD. …”
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Anticytotoxic T-Lymphocyte Antigen-4 Induced Autoimmune Hypophysitis: A Case Report and Literature Review by Deborah Majchel, Mary T. Korytkowski

“…It is important that endocrinologists become familiar with the endocrinopathies, such as autoimmune hypophysitis, associated with new immunomodulator agents which are being used with increasing frequency to treat a variety of malignancies.…”
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Hypoxanthine Derivatives in Experimental Infections by Claudio De Simone, Edoardo Arrigoni Martelli, Pietro Foresta, Giuseppe Famularo, Roberto Giacomelli, Emilio Jirillo, Vito Ruggiero, Giorgio Tonietti

“…These data, together with the recently shown ability of ST 789 to increase interleukin-6 production, suggest that monocyte/macrophages are likely to be the main cellular target of the immunomodulating activity of ST 789. Finally, in the presentln vivo study, hypoxanthine derivatives did not enhance the mean survival time of tumour-bearing immunosuppressed mice.…”
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