Development of a prognostic model based on four genes related to exhausted CD8+ T cell in triple-negative breast cancer patients: a comprehensive analysis integrating scRNA-seq and... by Yulin Shi, Yang Yu, Jiahan Zhao, Linan Huang, Qingyang Wang, Qi Sun, Lijuan Liu, Changgang Sun

“…The model demonstrated robust predictive capability in both the TCGA cohort and an external cohort, with the low-risk group exhibiting elevated expression of immunological checkpoint molecules and immune cell infiltration, as well as better responses to immunotherapy and chemotherapy. …”
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Clinical Holistic Medicine: The Patient with Multiple Diseases by Søren Ventegodt, Joav Merrick

“…She had a combination of neurological disturbances (tinnitus, migraine, minor hallucinations), immunological disturbances (recurrent herpes simplex, phlegm in the throat, fungal infection in the crotch), hormonal disturbances (14 days of menstruation in each cycle), muscle disturbances (neck tensions), mental disturbances (tendency to cry, inferiority feeling, mild depression, desolation, anxiety), abdominal complaints, hemorrhoids, and more. …”
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An Eight-Month-Old Child with Cervical Adenitis by Melanie CM Murray, Jacqueline Cooper, Patrick Tang, Jan Hajek, Tobias R Kollman

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Clinico-pathological profile of patients with HIV and tuberculosis co-infection by Cheryl Sarah Philipose, Sinchana KM, Haritha Haridas, John Ramapuram, Sharada Rai

“…TB and HIV increase progressive deterioration of immunological functions by speeding progression of one another. …”
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Joint use of polyvalent serum and immunomodulators for calves in early postnatal period by N. V. Shanshin

“…The paper demonstrates how a joint use of polyvalent serum and immunomodulators affects morbidity, survival, and resistance of calves in the early postnatal period.The objectives of the research are: to study how a joint administration of polyvalent serum and immunomodulators changes dynamics of morpho-biochemical and immunological blood parameters in calves; to determine an optimal ratio between the polyvalent serum and immunomodulators and frequency of administration so that to increase overall body resistance, ensure survival of calves in the early postnatal period; to assess cost-effectiveness of the joint use of polyvalent serum and immunomodulators. …”
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The necessity of cell banks by A. G. Menzorov, O. L. Serov

“…Production of a patient’s iPSCs, their differentiation into somatic cells, and subsequent transplantation to a patient would allow them to avoid immunological rejection. In addition, a recently developed technology of directed genome modification, CRISPR/Cas, allows correction of genetic mutations in iPSCs. …”
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Discovering the anti-parasitic activity of melatonin loaded lecithin/chitosan nanoparticles against giardiasis and cryptosporidiosis in Balb/c infected mice by Mohamed Nasser, Mona B. Abd El-atif, Habiba Alaa, Mariam Abdelaziz, Mariam Mustafa, Mustafa Masour, Salma Magdy, Salma Mohsen, Yomna El Karamany, Alyaa Farid

“…Conclusion Mel-LCNPs were highly effective preparations against giardiasis and cryptosporidiosis in Balb/c mice experimentally infected with proved antioxidant, anti-inflammatory, and immunological modulatory characteristics.…”
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Gene Polymorphism of Antigen B Subunit 2 and Pathogenesis of Cystic Echinococcosis in Murine Model by Hadi M. Alsakee, Hussein M. Abdulla, Reshna K. Albarzanji

“…To upgrade the diagnostic sensitivity rates of the immunological techniques, a mixture of native hydatid antigens containing AgB is recommended to be used in the ser-diagnosis of this infection. …”
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Neoadjuvant Chemoradiotherapy Upregulates the Immunogenicity of Cold to Hot Tumors in Esophageal Cancer Patients by Yushi Nagaki, MD, PhD, Satoru Motoyama, MD, PhD, Yusuke Sato, MD, PhD, Akiyuki Wakita, MD, PhD, Hiromu Fujita, MD, PhD, Kohei Kemuriyama, MD, Ryohei Sasamori, MD, Shu Nozaki, MD, Kyoko Nomura, MD, PhD, Yoshihiro Minamiya, MD, PhD

“…There have been several recent reports showing the efficacy of immune check-point inhibitors (ICIs) against esophageal cancer, especially immunologically hot tumors. In addition, several studies have suggested that chemotherapy and radiotherapy may convert cold tumors to hot tumors. …”
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Functional activity of blood eosinophils in patients with <i>Opisthorchis felineus</i> invasion by V. V. Tsukanov, N. E. Veselova, A. A. Savchenko, O. A. Kolenchukova, I. I. Gvozdev, A. V. Vasyutin, J. L. Tonkikh, E. V. Kasparov, A. G. Borisov, E. G. Gorchilova, M. Yu. Olkhovskaia, N. O. Prokopieva

“…Patients with O. felineus invasion with an increase in the content of eosinophils in the blood due to the likelihood of an aggressive course of the pathology deserve the close attention of practitioners with the need for a thorough comprehensive examination of patients, including immunological methods.…”
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Effects of Traumeel (Tr14) on Exercise-Induced Muscle Damage Response in Healthy Subjects: A Double-Blind RCT by Kerstin Muders, Christian Pilat, Vanessa Deuster, Torsten Frech, Karsten Krüger, Jörn Pons-Kühnemann, Frank-Christoph Mooren

“…Changes in postexercise levels of various serum muscle damage and immunological markers were investigated. The area under the curve with respect to the increase (AUCi) of perceived pain score and creatine kinase (CK) were defined as primary outcome measures. …”
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B-cell non-Hodgkin's lymphoma in the patient with chronic hepatitis C and mixed cryoglobulinemia by V. S. Adonyeva, Ye. A. Kolodyazhnaya, A. B. Bochkarev

“…Laboratory tests revealed moderate cytolytical activity: alanine transaminase (ALT) was 135 U/ml, aspartate aminotransferase (AST) —140 U/ml. Immunologic tests have confirmed the presence of HCV (RNA HCV — 15374 IU, genotype 1b). …”
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Development of a Recombinant Omicron BA.1 Subunit Vaccine Candidate in Pichia pastoris by Sibel Kalyoncu, Dogu Sayili, Ayca Zeybek Kuyucu, Hakan Soyturk, Seyda Gullu, Busra Ersayan, Ibrahim Oguzhan Tarman, Mehmet Ender Avci, Olcay Mert, Umut Haskok, Ege Tekin, Huseyin Akinturk, Ridvan Orkut, Aysegul Demirtas, Idil Tilmensagir, Ceren Ulker, Bilgi Gungor, Mehmet Inan

“…These serum antibodies also recognized earlier (Delta Plus: B.1.617.2) and later (Eris: EG.5, Pirola: BA.2.86) SARS‐CoV2 variants. The long‐term immunological response in mice was measured by analyzing serum antibody titers and T‐cell response of splenocytes after 60 weeks. …”
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Deferiprone ameliorates cisplatin induced peripheral neurotoxicity via ferritinophagy adjustment by Hanan Seddiek, Mira Hanna, Amany Elsayed Mohamed Hamoud, Marawan Abd Elbaset, Ahmed M. A. Akabawy, Mohamed Zakaria Kotb, Mohamed Mansour Khalifa

“…In addition to significant deterioration in the histopathological and immunological nerve tissue assessment using silver stain and PNCA. …”
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Importance of complement system components in ovarian endometriomas. A comparative cohort study by Anna V. Chizhova, Elena V. Kudryavtseva, Larisa G. Polushina, Maksim A. Kopenkin

“…It may indicate that surgical treatment of endometrioma affects the overall immunological phenotype. Conclusion. C3 and C4 levels in women with ovarian endometriomas are higher compared to those in patients with other benign ovarian masses. …”
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Nanobody screening and machine learning guided identification of cross-variant anti-SARS-CoV-2 neutralizing heavy-chain only antibodies. by Peter R McIlroy, Le Thanh Mai Pham, Thomas Sheffield, Maxwell A Stefan, Christine E Thatcher, James Jaryenneh, Jennifer L Schwedler, Anupama Sinha, Christopher A Sumner, Iris K A Jones, Stephen Won, Ryan C Bruneau, Dina R Weilhammer, Zhuoming Liu, Sean Whelan, Oscar A Negrete, Kenneth L Sale, Brooke Harmon

“…Development of new vaccines and antibodies for emerging viral threats requires substantial resources and time, and traditional development platforms for vaccines and antibodies are often too slow to combat continuously evolving immunological escape variants, reducing their efficacy over time. …”
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Correlation and diagnostic significance of CD4 T cell subsets and NLRP3 inflammasome in ulcerative colitis: the role of the NLRP3/T-bet/GATA3 axis by Yingnan Hu, Jingyi Tang, Dian Yu, Shuo Su, Jintao Fang, Linying Xia, Wenjun Xu, Weihan Zhu, Ninping Song, Fengyong Wang, Dechang Diao, Wei Zhang

“…Abstract Background and aim Ulcerative colitis (UC) is characterized by complex immunological interactions involving CD4 T cell subsets and the NLRP3 inflammasome, which influence inflammatory responses. …”
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Effect of non-surgical periodontal therapy on salivary and gingival crevicular fluid concentration of visfatin in periodontal health and disease by Hira Ismail, Anjani Kumar Pathak, Nand Lal, Pavitra Rastogi, Kaleem Ahmad, Mohd. Aamir Khan

“…Background and objective: Visfatin, a pleotropic mediator mostly produced by visceral fat, is crucial in controlling the immunological and defensive systems. It serves the roles of a cytokine, an enzyme involved in energy metabolism, and a growth factor. …”
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Anti-Inflammatory Effects of Cannabigerol In Vitro and In Vivo Are Mediated Through the JAK/STAT/NFκB Signaling Pathway by Ga Hee Jeong, Ki Chan Kim, Ji Hyun Lee

“…In the mouse model, clinical, histological, and immunological changes were analyzed. The results showed that CBG improved dermatitis severity score, epidermal thickness, and mast cell count and reduced inflammatory cytokines (<i>Tslp</i>, <i>Il1b</i>, <i>Il4</i>, <i>Il6</i>, <i>Il13</i>, <i>Il17</i>, <i>Il18</i>, <i>Il22</i>, and <i>Il33</i>) by qRT-PCR (<i>p</i> < 0.001). …”
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