Does Clostridium Perfringens Epsilon Toxin Mimic an Auto-Antigen Involved in Multiple Sclerosis? by Marie-Lise Gougeon, Valérie Seffer, Cezarela Hoxha, Elisabeth Maillart, Michel R. Popoff

“…They rather argue for a cross immunological reactivity with an antigen, possibly an autoantigen, mimicking ETX. …”
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GagCM9-specific CD8+ T cells expressing limited public TCR clonotypes do not suppress SIV replication in vivo. by Lara Vojnov, Mauricio A Martins, Jorge R Almeida, Zachary Ende, Eva G Rakasz, Matthew R Reynolds, Enrique J Leon, Kim L Weisgrau, Benjamin J Burwitz, Joy M Folkvord, Marlon G Veloso de Santana, Patrícia C Costa Neves, Elizabeth Connick, Pamela J Skinner, Emma Gostick, David H O'Connor, Nancy A Wilson, Myrna C Bonaldo, Ricardo Galler, David A Price, Danny C Douek, David I Watkins

“…We carried out a series of immunological and virological assays to understand why these Gag-specific CD8(+) T cells could not control virus replication in vivo. …”
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DeepDrug as an expert guided and AI driven drug repurposing methodology for selecting the lead combination of drugs for Alzheimer’s disease by Victor O. K. Li, Yang Han, Tushar Kaistha, Qi Zhang, Jocelyn Downey, Illana Gozes, Jacqueline C. K. Lam

“…Firstly, it incorporates expert knowledge to extend candidate targets to include long genes, immunological and aging pathways, and somatic mutation markers that are associated with AD. …”
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Fulminant Diabetes in a Patient with Advanced Melanoma on Nivolumab by Nora Chokr, Hafsa Farooq, Elizabeth Guadalupe

“…Anti-PD-1 agents can breach immunologic tolerance. Fulminant diabetes is an immune endocrinopathy that results from a violent immune attack leading to complete destruction of pancreatic beta cells in genetically predisposed people. …”
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A rare case of temporal arteritis in a young Indian male by Debaditya Roy, Susmita Rakshit, Azeez Pasha, Abhishek Patil

“…The evaluation revealed normal routine laboratory parameters and inflammatory markers. Immunological and viral markers' workup was also normal. …”
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Evaluation of Protocol Biopsy Utility 12 Months after Renal Transplantation: A Multicenter Observational Analysis by Bruno Moulin, Pierre Merville, Karine Renaudin, David Buob, Sophie Ferlicot, Michel Delahousse, Jacques Dantal, Laetitia Albano, Christelle Barbet, Georges Mourad, Laure-Hélène Noel

“…Globally, most recipients in both cohorts were at low immunological risk (<10% of patients with PRA ≥30%). …”
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Clinical Features and Dynamics of T Cells-Related Markers in Immunocompetent Patients with Cytomegalovirus Hepatitis by Takuya Komura, Takashi Kagaya, Hideo Takayama, Masahiro Yanagi, Takatoshi Yoshio, Saiho Sugimoto, Michiko Nishino, Noriaki Orita, Yoshiro Asahina, Masashi Nishikawa, Shuichi Kaneko, Masashi Unoura

“…We evaluated the pathophysiology and immunological aspects of CMV hepatitis in recently immunocompetent adult patients. …”
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Effects of Single-Nucleotide Polymorphisms in Cytokine, Toll-Like Receptor, and Progesterone Receptor Genes on Risk of Miscarriage by Anastasiia Razdaibiedina, Mykhaylo Khobzey, Victoria Tkachenko, Iryna Vorobiova

“…Spontaneous abortion is a complex, multifactorial pathology, where various genetic, neural, endocrine, and immunological factors are involved. Cytokines, Toll-like receptors, and progesterone receptors play critical roles in embryonic implantation and development. …”
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Gut microbiota and atrial cardiomyopathy by Tingting Sun, Beibei Song, Bo Li

“…Its etiology involves a number of factors, including genetic, infectious, immunologic, and metabolic factors. Recent research has highlighted the critical role of the gut microbiota in the pathogenesis of atrial cardiomyopathy, and this is consistent with the gut–heart axis having major implications for cardiac health. …”
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Prospective and Longitudinal Analysis of Lymphocyte Subpopulations in SARS-CoV-2 Positive and Negative Pneumonia: Potential Role of Decreased Naïve CD8⁺ in COVID-19 Pati... by Makhabbat Bekbossynova, Lyudmila Akhmaltdinova, Kuanysh Dossybayeva, Ainur Tauekelova, Zauresh Smagulova, Tatyana Tsechoeva, Gulsimzhan Turebayeva, Aliya Sailybayeva, Zhanar Kalila, Takhmina Mirashirova, Timur Muratov, Dimitri Poddighe

“…<b>Background</b>: During the acute phase of COVID-19, a number of immunological abnormalities have been reported, but few studies longitudinally analyzed the specific subsets of peripheral blood lymphocytes. …”
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Complement protein and Immunoglobulins Serum levels in Normal Pregnant and Spontaneous Aborted Women by Hiwa Abdulrahman Ahmad, Mehri Mirhaj Muhammd salih, Kamal Ahmed Khidir

“…Disorder of maternal immune responses during pregnancy triggers immunological rejection of fetus antigens by maternal immune components, contribute to spontaneous abortion or miscarriage. …”
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High p16INK4A expression in glioblastoma is associated with senescence phenotype and better prognosis by Soon Sang Park, Tae Hoon Roh, Yoshiaki Tanaka, Young Hwa Kim, So Hyun Park, Tae-Gyu Kim, So Yeong Eom, Tae Jun Park, In-Hyun Park, Se-Hyuk Kim, Jang-Hee Kim

“…These findings suggest that tumor cells with a senescence phenotype in GBM, through the secretion of chemokines such as CCL13, may augment immune cell infiltration and potentially enhance patient outcomes by creating a more immunologically active tumor microenvironment.…”
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Identification of key regulators in pancreatic ductal adenocarcinoma using network theoretical approach. by Kankana Bhattacharjee, Aryya Ghosh

“…The disease's development involves complex interactions among immunological, genetic, and environmental factors, yet its molecular mechanism remains elusive. …”
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Pericardial Involvement in Hereditary Hemorrhagic Telangiectasia by Abir Derbel, Mouna Snoussi, Raida Ben Salah, Faten Frikha, Leila Abid, Imed Frikha, Sameh Marzouk, Zouhir Bahloul

“…Viral investigations and immunologic tests were negative. Abdominal tomography showed multiple arterio-venous shunts of the liver. …”
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APLASTIC SYNDROME IN A PREGNANT WOMAN ON THE BACKGROUND OF COVID-19: A CLINICAL CASE by Индира Венеровна Сахаутдинова, Ирина Борисовна Фаткуллина, Ирина Робинзоновна Рахматуллина, Игорь Сергеевич Засядкин, Анна Юрьевна Лазарева

“…Women during the gestational process have high risks of contracting the new coronavirus infection COVID-19 due to significant immunological changes in the body of the expectant mother. …”
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Spatial transcriptome reveals histology-correlated immune signature learnt by deep learning attention mechanism on H&E-stained images for ovarian cancer prognosis by Chun Wai Ng, Kwong-Kwok Wong, Barrett C. Lawson, Sammy Ferri-Borgogno, Samuel C. Mok

“…This could guide future pathological study for the useful immunological features that are important in modulating the prognosis of ovarian cancer patients.…”
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Causal relationship between immune cells and risk of heart failure: evidence from a Mendelian randomization study by Wenjing Cao, Zefu Yang, Liumei Mo, Zhenhao Liu, Jiawei Wang, Zhenhong Zhang, Kui Wang, Wei Pan

“…The objective of the current research was to explore the potential connections between immune characteristics and the development of HF, as well as to ascertain the nature of the causality between these factors.MethodsTo assess the causal association of immunological profiles with HF based on publicly available genome-wide studies, we employed a two-sample Mendelian randomization technique, utilizing the inverse variance weighted (IVW) method as our primary analytical approach. …”
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Model analysis for an HIV infectious disease using elasticity and sensitivity techniques by Honar J. Hamad, Sarbaz H. A. Khoshnaw, Muhammad Shahzad

“…The human immunodeficiency virus (HIV) is an infection that mainly impacts CD4+ T cells inside the immune system, causing a gradual decline in immunological function. If untreated, this can lead to acquired immunodeficiency syndrome (AIDS), a disorder in which the body becomes extremely susceptible to opportunistic infections due to a severely compromised immune system. …”
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Immunotherapy in Recurrent Ovarian Cancer by Keyao Chen, Jingjing Wang, Meng Yang, Shaoqiong Deng, Li Sun

“…The immune microenvironment in platinum-sensitive and -resistant cases exhibits distinct immunological profiles, influencing therapy outcomes. …”
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LEVEL OF PROCALCITONIN PLASMA AS AN EARLY SEPSIS BIOMARKER IN POLYTRAUMA PATIENTS IN DR HASAN SADIKIN GENERAL HOSPITAL BANDUNG by Ricky Wibowo, Hermawan Nagar Rasyid, Darmadji Ismono

“…Background: Polytrauma patients have a risk of progressive organ dysfunction due to uncontrolled immunological process. Sepsis and multiple organ failure are the most common causes of morbidity and mortality in late death of polytrauma patients. …”
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