Primary biliary cirrhosis: clinical and laboratory criteria of diagnostics and up-to-date treatment by L. Yu. Il’chenko, V. I. Reshetn’yak

“…АМА-positive (classical) variant of PBC with pruritus, jaundice, biochemical syndrome of cholestasis and revealing of AMA in diagnostic titer (more 1:40) in blood serum is defined; АМА-negative variant of PBC with lower biochemical and immunologic activity, lower frequency of extrahepatic manifestations, that, however, does not influence the prognosis and terms of LC progression; overlap syndrome with autoimmune hepatitis (AIH) – PBC/AIH (9,4%); asymptomatic course of PBC which is characterized by absence of clinical symptoms for a long period and manifestation of disease at the stage of LC complications. …”
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Genetic Factors in Animal Models of Intestinal Inflammation by R Balfour Sartor

“…Identification of the immunological mechanisms of host genetic susceptibility and the genetic basis of spontaneous colitis should provide new insights into the pathogenesis of human inflammatory bowel disease.…”
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Tissue Engineering of Urinary Bladder and Urethra: Advances from Bench to Patients by Hazem Orabi, Sara Bouhout, Amélie Morissette, Alexandre Rousseau, Stéphane Chabaud, Stéphane Bolduc

“…This self-assembly technique avoids the biosafety and immunological reactions related to the use of biodegradable scaffolds. …”
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Identification of a novel immunogenic cell death-related classifier to predict prognosis and optimize precision treatment in hepatocellular carcinoma by Dongjing Zhang, Bingyun Lu, Qianqian Ma, Wen Xu, Qi Zhang, Zhiqi Xiao, Yuanheng Li, Ren Chen, An-jiang Wang

“…A reliable risk model named ICD score was constructed via machine learning algorithms to assess the immunological status, therapeutic responses, and clinical outcomes of individual HCC patients. …”
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CXC Chemokines in the Pathogenesis of Pulmonary Disease and Pharmacological Relevance by Kayode Komolafe, Maricica Pacurari

“…These chemokines and their receptors are expected to have a significant impact on a wide range of lung diseases, many of which have inflammatory or immunological underpinnings. As a result, manipulations of this subfamily of chemokines and their receptors using small molecular agents and other means have been explored for potential therapeutic benefit in the setting of several lung pathologies. …”
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Current Advance and Future Prospects of Tissue Engineering Approach to Dentin/Pulp Regenerative Therapy by Ting Gong, Boon Chin Heng, Edward Chin Man Lo, Chengfei Zhang

“…Apart from the potential health risks of immunological rejection and pathogenic transmission, the lack of a well-established banking system for the isolation and storage of dental-derived stem cells is the most pressing issue that awaits resolution and the properties of supportive scaffold materials vary across different studies and remain inconsistent. …”
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Case Report: Pediatric pontine abscess and ecthyma gangrenosum due to Pseudomonas aeruginosa septicemia by Jonathan Theros, Madison Wolfe, Larry Kociolek, Larry Kociolek, Irini N. Kolaitis, Irini N. Kolaitis

“…Extensive immunodeficiency workup did not identify an immunologic defect. Prompt action through interdisciplinary care meetings and avoidance of early diagnostic closure resulted in an excellent neurological outcome for this patient with this rare case of a P. aeruginosa brainstem abscess.…”
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Advances in the Drugs Treatment of Psoriatic Arthritis by LU Chaofan, LENG Xiaomei

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Polyarticular Septic Arthritis Caused by Haemophilus influenzae Serotype f in an 8-Month-Old Immunocompetent Infant: A Case Report and Review of the Literature by Raheel Ahmed Ali, Sheldon L. Kaplan, Scott B. Rosenfeld

“…Optimal treatment includes surgical management, culture driven IV antibiotics, and an immunologic workup.…”
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Immune infiltrate populations within distinct tumor immune microenvironments predictive of immune checkpoint treatment outcome by Brian Z Ring, Catherine T. Cronister, Huijun Z. Ring, Douglas T. Ross, Robert S. Seitz

“…This signature of potentially conserved B-cell biology in co-infiltrated immune cell ecosystems had a more consistent association with outcome than comparable single cell type models and likely reflects a complex immunological response involving multilayered relationships between distinct immune effector cell types. …”
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Preventive Effect of TU-100 on a Type-2 Model of Colitis in Mice: Possible Involvement of Enhancing Adrenomedullin in Intestinal Epithelial Cells by Atsushi Kaneko, Toru Kono, Naoko Miura, Naoko Tsuchiya, Masahiro Yamamoto

“…Crohn's disease (CD) and ulcerative colitis (UC), the two major forms of inflammatory bowel disease (IBD), have histopathologically and immunologically different characteristics. We previously reported that a traditional Japanese medicine, daikenchuto (TU-100), ameliorated a trinitrobenzenesulfonic acid- (TNBS-) induced type-1 model colitis exhibiting histopathological features of CD through adrenomedullin (ADM) enhancement. …”
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Frequency of Genital Involvement in Women with Oral Lichen Planus in Southern Iran by M. Davarmanesh, A. Samsami Dehaghani, Z. Deilami, A. Monabbati, L. Dastgheib

“…Lichen Planus is a chronic mucocutaneous disease of immunological basis and unknown etiology. women with oral lichen planus may have concomitant manifestations in vulvovaginal areas. …”
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The use of hyaluronic acid fillers in patients with autoimmune endocrinopathies; in particular, women with Hashimoto’s disease – hints for aesthetic doctors by Katarzyna Bornikowska, Paweł Kubik, Wojciech Zgliczyński

“…Due to the dysfunction of the immune system in this group of patients, there is a higher risk of adverse side effects, especially those of immunological nature. Based on the available literature, the incidence of adverse reactions after the use of hyaluronic acid-based fillers amounts to 0.01–1% and is undoubtedly underestimated. …”
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Severe Aplastic Anemia following Acute Hepatitis from Toxic Liver Injury: Literature Review and Case Report of a Successful Outcome by Kamran Qureshi, Usman Sarwar, Hicham Khallafi

“…It is assumed that immunologic dysregulation following AH leads to the development of SAA. …”
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Changes in the Microbiome During Chronic Rhinosinusitis by Mateusz de Mezer, Nina Chalama, Cheyanna Bratt, Melanie Kiebalo, Natalia Dolata, Jan Rogaliński, Małgorzata Leszczyńska

“…Further investigation is needed to uncover the interplay between resident microbiota and viral, fungal, and immunological influence. Discerning between ‘healthy’ and ‘diseased’ sinonasal microbiomes and ‘keystone’ species could shed light on CRS etiology and provide the opportunity for CRS treatment tailored to an individual’s microbiome. …”
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Severe CSF immune cell alterations in cryptococcal meningitis gradually resolve during antifungal therapy by Christine Dambietz, Michael Heming, Tobias J. Brix, Andreas Schulte-Mecklenbeck, Phil-Robin Tepasse, Catharina C. Gross, Jonel Trebicka, Heinz Wiendl, Gerd Meyer zu Hörste

“…Host response and immunological alterations in the cerebrospinal fluid (CSF) after invasion of Cryptococcus neoformans to the central nervous system have been investigated before but rigorous and comprehensive studies examining cellular changes in the CSF of patients with cryptococccal meningitis are still rare. …”
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CELLULAR IMMUNITY AND CYTOKINE PROFILE IN PRE-FARROW AND LACTATING SOWS by A. G. Shakhov, S. V. Shabunin, L. Yu. Sashnina, M. I. Adodina, M. Yu. Zhejnes, K. V. Tarakanova, K. O. Kopytina

“…Before farrow, the animals demonstrated physiological immunodeficiency characterized by relative leukopenia and lymphopenia, decreased T-cell number, higher helper/suppressor ratio providing immunological tolerance in dam/fetus system. Their cytokine profile was specified by relatively deficient interleukin-1β and tumor necrosis factor-α indicative of immune system suppression and high level of γ-interferon involved in parturition and activation of suppressor cells. …”
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Histopathological, Immunohistochemical and Biochemical Studies of Murine Hepatosplenic Tissues Affected by Chronic Toxoplasmosis by Samah Hassan Yahia, Samia Elsayed Etewa, Nesreen Saeed Saleh, Samira Metwally Mohammad, Nora Ibrahim Aboulfotouh, Ahmad Mansour Kandil, Mohamed Hassan Sarhan

“…Our findings revealed the persistent effect of latent toxoplasmosis on the host’s histological architecture, metabolic, and immunological profile, creating a continued challenging host-parasite relationship.…”
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Protein Glycation in Diabetes as Determined by Mass Spectrometry by Annunziata Lapolla, Laura Molin, Pietro Traldi

“…Enzymatic degradation products of in vitro glycated HSA were studied in order to simulate the in vivo enzymatic digestion of glycated species by the immunological system leading to the highly reactive advanced glycation end-products (AGEs) peptides. …”
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Identifying effective immune biomarkers in alopecia areata diagnosis based on machine learning methods by Qingde Zhou, Lan Lan, Wei Wang, Xinchang Xu

“…Methods In this study, differential gene expression analysis, immune status assessment, weighted correlation network analysis (WGCNA), and functional enrichment analysis were performed to identify shared genes associated with both immunological response and AA. Machine learning methods were then used to identify three hub genes as potential diagnostic markers for AA. …”
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