Mechanisms of Chronic State of Inflammation as Mediators That Link Obese Adipose Tissue and Metabolic Syndrome by Eduardo Fuentes, Francisco Fuentes, Gemma Vilahur, Lina Badimon, Iván Palomo

Get full text

Chronic Urticaria: Indian Context—Challenges and Treatment Options by Sujoy Khan, Anirban Maitra, Pravin Hissaria, Sitesh Roy, Mahesh Padukudru Anand, Nalin Nag, Harpal Singh

Get full text

Central Role of Gimap5 in Maintaining Peripheral Tolerance and T Cell Homeostasis in the Gut by Mehari Endale, H. Ibrahim Aksoylar, Kasper Hoebe

“…Here, we discuss how defects in Gimap5 function impair immunological tolerance and lymphocyte survival and ultimately drive the development of CD4+ T cell-mediated early-onset colitis.…”
Get full text

Potential of Peroxisome Proliferator-Activated Receptor Gamma Antagonist Compounds as Therapeutic Agents for a Wide Range of Cancer Types by Jack D. Burton, David M. Goldenberg, Rosalyn D. Blumenthal

Get full text

A Purely Biomanufactured System for Delivering Nanoparticles and STING Agonists by Yu‐an Li, Yi Feng, Wenjing Li, Yuqin Zhang, Yanni Sun, Shifeng Wang, Roy Curtiss III, Huoying Shi

Get full text

Porphyromonas gingivalis associates with the presence of anti-citrullinated protein antibodies, but not with the onset of arthritis: studies in an at-risk population by Helga Westerlind, Linda Mathsson-Alm, Alexandra Circiumaru, Aase Hensvold, Karin Lundberg, Jan Potempa, Yogan Kisten, Charlotte De Vries, Marina Dehara, Barbara Potempa

Get full text

Blockades of effector T cell senescence and exhaustion synergistically enhance antitumor immunity and immunotherapy by Xia Liu, Emily Shaw, Fusheng Si, Guangyong Peng, Yan Tao, Feiya Ma, David Bagley, Yuanqin Zhang

Get full text

Targeted dual biologic therapy for erythroderma of unknown etiology guided by high-parameter peripheral blood immunophenotyping by Hannah L. Cornman, Martin P. Alphonse, Arbor Dykema, Alexander L. Kollhoff, Kevin K. Lee, Jaya Manjunath, Emily Z Ma, Varsha Parthasarathy, Junwen Deng, Thomas Pritchard, Anusha Kambala, Melika Marani, Kayla A. Parr, Javid P. Mohammed, Madan M. Kwatra, Jay H. Bream, Won Jin Ho, Shawn G. Kwatra

Get full text

METTL16 controls airway inflammations in smoking-induced COPD via regulating glutamine metabolism by Xinyu Jia, Shan Liu, Chunan Sun, Manni Zhu, Qi Yuan, Min Wang, Tingting Xu, Zhengxia Wang, Zhongqi Chen, Mao Huang, Ningfei Ji, Mingshun Zhang

Get full text

Safety and efficacy of switching from adalimumab to sarilumab in patients with rheumatoid arthritis in the ongoing MONARCH open-label extension by Gerd R Burmester, Mark C Genovese, Vibeke Strand, Gregory St John, Andrea Rubbert-Roth, Howard Amital, Tatiana Raskina, Antonio Gómez-Centeno, Claudia Pena-Rossi, Leon Gervitz, Karthinathan Thangavelu, Susan Boklage

Get full text

Utilizing Technology-Enabled Intervention to Improve Blood Glucose Self-Management Outcome in Type 2 Diabetic Patients Initiated on Insulin Therapy: A Retrospective Real-World Stud... by Jian Lin, Xia Li, Shan Jiang, Xiao Ma, Yuxin Yang, Zhiguang Zhou

Get full text

Clinically relevant orthotopic pancreatic cancer models for adoptive T cell transfer therapy by Gregory B. Lesinski, Chrystal M. Paulos, Maggie Phillips, Jacklyn Hammons, Isaac Karpovsky, Zaid Mahdi, Natalie K. Horvat, Megan M. Wyatt, Margaret A. Hall, Cameron J. Herting, Richard A. Moffitt

“…However, these models have limitations, including marked tumor variability across individual mice and the cost of colony maintenance.Methods Using flow cytometry and immunohistochemistry, we characterized the immunological features and trafficking patterns of adoptively transferred T cells in orthotopic PDAC (C57BL/6) models using two mouse cell lines, KPC-Luc and MT-5, isolated from C57BL/6 KPC-GEMM (KrasLSL-G12D/+p53−/− and KrasLSL-G12D/+p53LSL-R172H/+, respectively).Results The MT-5 orthotopic model best recapitulates the cellular and stromal features of the TME in the PDAC GEMM. …”
Get full text

Transposon-sequencing across multiple Mycobacterium abscessus isolates reveals significant functional genomic diversity among strains by Chidiebere Akusobi, Sanjeevani Choudhery, Bouchra S. Benghomari, Ian D. Wolf, Shreya Singhvi, Thomas R. Ioerger, Eric J. Rubin

Get full text

Chemokines by Richard Horuk

Get full text

Host Defence to Pulmonary Mycosis by Christopher H Mody, Peter W Warren

“…This will help physicians understand why some patients are predisposed to fungal infections and update basic scientists on how microbial immunology applies to fungal disease.…”
Get full text

Impact and Challenges of Mesenchymal Stem Cells in Medicine: An Overview of the Current Knowledge by Farid Menaa, Somayeh Shahrokhi, V. Prasad Shastri

Get full text

Prevalence of Work-Related Respiratory Symptoms in Iranian Farmers by N Hashemi, M Mirsadraee, MT Shakeri, AR Varasteh

Get full text

Mediators of Inflammation and Immune Responses in the Human Gastrointestinal Tract by E. Arranz, A. S. Peña, D. Bernardo

Get full text

A Review of 11 Years of Stenotrophomonas maltophilia Blood Isolates at a Tertiary Care Institute in Canada by Prenilla Naidu, Stephanie Smith

Get full text

Inflammation in Retinal Disease by Scott M. Whitcup, Robert B. Nussenblatt, Susan L. Lightman, David A. Hollander

Get full text