Break through the mold: Hyper-IgE syndrome as a vehicle for invasive aspergillosis by Joseph Nordin, Stephen Smetana, Rachel Johnson, Angela Bartosiak, Nicholas Nassif

“…Hyperimmunoglobulin E syndrome (HIGES) is a rare immunodeficiency characterized by high levels of immunoglobulin E (IgE) in the setting of various clinical features such as cutaneous candidiasis, asthma, recurrent rashes, and fungal infections. …”
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Regulated microbe vaccines: from concept to (pre-clinical) reduction to practice by Richard Voellmy, David C Bloom, Nuria Vilaboa

“…SARS-CoV-2), respiratory syncytial viruses (RSV), and human immunodeficiency viruses (HIV) have remained insufficiently effective or are not available at all. …”
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Cytokines and Chemokines at the Crossroads of Neuroinflammation, Neurodegeneration, and Neuropathic Pain by Geeta Ramesh, Andrew G. MacLean, Mario T. Philipp

“…This review will focus on how cytokines and chemokines affect neuroinflammation and disease pathogenesis in bacterial meningitis and brain abscesses, Lyme neuroborreliosis, human immunodeficiency virus encephalitis, and neuropathic pain.…”
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Pneumocystis jirovecii Pneumonia in a HIV-Infected Patient with a CD4 Count Greater Than 400 Cells/μL and Atovaquone Prophylaxis by Abigayle Sullivan, Theresa Lanham, Ronald Krol, Shilla Zachariah

“…We describe a rare case of Pneumocystis jirovecii pneumonia (PCP) in a heterosexual man with a pertinent medical history of well-controlled human immunodeficiency virus (HIV) on highly active antiretroviral therapy (HAART) and PCP prophylaxis with atovaquone. …”
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The Immune Response and Its Therapeutic Modulation in Bronchiectasis by Massoud Daheshia, James D. Prahl, Jacob J. Carmichael, John S. Parrish, Gilbert Seda

“…Interestingly, a defect in the immune system or suppression of immune response during conditions such as immunodeficiency may well predispose one to the devastating effects of BC. …”
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T Cell Activation and Regulation of HIV-1: Same Effectors with Distinct Outcomes by Jean-François Fortin, Benoit Barbeau, Gilles A Robichaud, Michel J Tremblay

“…The molecular mechanisms that regulate the function of the immune system and human immunodeficiency virus type-1 (HIV-1) gene expression are diverse and complicated. …”
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Structural insights into HIV-2 CA lattice formation and FG-pocket binding revealed by single-particle cryo-EM by Matthew Cook, Christian Freniere, Chunxiang Wu, Faith Lozano, Yong Xiong

“…Summary: One of the striking features of human immunodeficiency virus (HIV) is the capsid, a fullerene cone comprised of pleomorphic capsid protein (CA) that shields the viral genome and recruits cofactors. …”
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Empedobacter brevis Bacteremia in a Patient Infected with HIV: Case Report and Review of Literature by Syed Bokhari, Naeem Abbas, Manisha Singh, Richard B. Cindrich, Cosmina Zeana

“…A 69-year-old man with human immunodeficiency virus (HIV) and CD4 count of 319 presented with chief complaints of black tarry stools, nausea and vomiting for 2 days. …”
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A Girl with Autoimmune Cytopenias, Nonmalignant Lymphadenopathy, and Recurrent Infections by Marjolein A. C. Mattheij, Ellen J. H. Schatorjé, Eugenie F. A. Gemen, Lisette van de Corput, Peet T. G. A. Nooijen, Mirjam van der Burg, Esther de Vries

“…Her symptoms partly fit the definitions of both autoimmune lymphoproliferative syndrome (ALPS) and common variable immunodeficiency disorders (CVIDs). Genetic analysis showed no abnormalities in the ALPS-genes FAS, FASLG, and CASP10. …”
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Rituximab Monotherapy in the Management of a Rare Case of an HIV Associated Lymphoproliferative Disorder by Jason Hew, Fauzia Rana, Louise Zhou

“…MCD is often associated with human immunodeficiency virus (HIV) infection and these patients are usually coinfected with human herpes virus-8 (HHV-8). …”
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Predictors associated with time to default for HIV/AIDS patients under HAART at Debre Tabor Referral Hospital: a Cox regression model by Koyachew Bitew Abebe

“…Abstract The human immunodeficiency virus systematically undermines the immune system, which serves as our body’s inherent safeguard against diseases. …”
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HIV, smoking, and the brain: a convergence of neurotoxicities by Benjamin L. Orlinick, Shelli F. Farhadian

“…Abstract Purpose of review The purpose of this review is to characterize the combined effects of tobacco smoking and human immunodeficiency virus (HIV) infection in people with HIV (PWH) and identify possible therapeutic targets through shared mechanisms for neurotoxicity. …”
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Is PPAR𝛾 a Prospective Player in HIV-1-Associated Bone Disease? by Eoin J. Cotter, Patrick W. Mallon, Peter P. Doran

“…Currently infection with the human immunodeficiency virus-1 (HIV-1) is in most instances a chronic disease that can be controlled by effective antiretroviral therapy (ART). …”
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Polyarticular Septic Arthritis Caused by Haemophilus influenzae Serotype f in an 8-Month-Old Immunocompetent Infant: A Case Report and Review of the Literature by Raheel Ahmed Ali, Sheldon L. Kaplan, Scott B. Rosenfeld

“…Haemophilus influenzae non-type b may cause serious invasive infections such as sepsis or septic arthritis in children with or without predisposing factors such as immunodeficiency or asplenia. Optimal treatment includes surgical management, culture driven IV antibiotics, and an immunologic workup.…”
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Educators’ perceptions of the life orientation programme in schools and its effect on HIV/AIDS by Abiodun Folakemi Fatoba, Daniel Angaama, Meshach Bolaji Ogunniyi

“…Before the programme was introduced in the 2006, many learners had become infected with human immunodeficiency virus (HIV). The programme was introduced based on the perceptions that some learners were struggling as a result of the epidemic. …”
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Prevalence of Blood-Borne Viruses in Health Care Workers of a Northern District in Pakistan: Risk Factors and Preventive Behaviors by Muhammad Zuhaib Khan, Shahab Saqib, Sayed Irtiza Hussain Shah Gardyzi, Javaria Qazi

“…There is also a potential threat of human immunodeficiency virus (HIV) spread in the country. Health care workers (HCWs) are a high risk population for acquiring such viral infections and potential spread to the patients. …”
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Successful Integration of Hepatitis C Virus Point-of-Care Tests into the Denver Metro Health Clinic by A. Jewett, A. A. Al-Tayyib, L. Ginnett, B. D. Smith

“…The Centers for Disease Control and Prevention (CDC) recommends testing and linkage to care for persons most likely infected with hepatitis C virus (HCV), including persons with human immunodeficiency virus. We explored facilitators and barriers to integrating HCV point-of-care (POC) testing into standard operations at an urban STD clinic. …”
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A case of acute brucellosis associated with HIV infection in Turkey by Fatma Yekta Urkmez, Sevil Alkan

“…Human brucellosis is a common public health problem in Turkey. Human immunodeficiency virus (HIV)-positive patients are vulnerable to co-infections and super-infections due to targeting the immune system. …”
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Study protocol for a multi-center stepped-wedge cluster randomized trial to explore the usability and outcomes among young people living with HIV in Kiambu and Kirinyaga counties o... by Eric Nturibi, Jared Mecha, Elizabeth Kubo, Albert Orwa, Florence Kaara, Faith Musau, Christine Wamuyu, Justus Kilonzi, Randeep Gill, Sanne Roels

“…While the incidence of Human Immunodeficiency Virus (HIV) infection is decreasing in most age groups worldwide, it is rising among adolescents and young adults, who also face a higher rate of HIV-related deaths. …”
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The Story of CD4+CD28− T Cells Revisited: Solved or Still Ongoing? by Kathrin Maly, Michael Schirmer

“…In healthy individuals older than 65 years, these cells may accumulate to up to 50% of total CD4+ T lymphocytes as in many immune-mediated diseases, immunodeficiency, and specific infectious diseases. Here we focus on CD4+CD28− T cells in chronic immune-mediated diseases, summarizing various phenotypic and functional characteristics, which vary depending on the underlying disease, disease activity, and concurrent treatment. …”
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