Mutation of isocitrate dehydrogenase indicates favorable outcomes in pan-cancer immune checkpoint blockade by Zhiyang Huang, Yingying Li, Hong Zhao, Bin Zhao

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Thioredoxin: a key factor in cold tumor formation and a promising biomarker for immunotherapy resistance in NSCLC by Jiayi Hu, Yilimunuer Abulimiti, Haiyang Wang, Dianyu Yang, Xu Wang, Yang Wang, Ping Ji

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Potentiation of immune checkpoint blockade with an ITPP radiosensitizer studied with oxygen saturation measurements from photoacoustic imaging by Renee L. Tran, Xiaofei Liang, Jorge de la Cerda, F. William Schuler, Mark D. Pagel

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Cryoablation combined with dual immune checkpoint blockade enhances antitumor efficacy in hepatocellular carcinoma model mice by Jun Gu, Zepeng Yu, Xiangxiang Tang, Wenying Chen, Xuedong Deng, Xiaoli Zhu

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Injectable celastrol-loading emulsion hydrogel for immunotherapy of low-immunogenic cancer by Yu Liu, Jia Zhang, Chunyu Lai, Wenjun Wang, Yangyue Huang, Xuanwen Bao, Haimeng Yan, Xuqi Sun, Qiqi Liu, Dong Chen, Xiaomeng Dai, Xinyu Qian, Peng Zhao

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M2 macrophage-derived exosomes suppress tumor intrinsic immunogenicity to confer immunotherapy resistance by Naisheng Zheng, Tingting Wang, Qin Luo, Yi Liu, Junyao Yang, Yunlan Zhou, Guohua Xie, Yanhui Ma, Xiangliang Yuan, Lisong Shen

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An immune activator encapsulating PD-L1 siRNA for augmented immune checkpoint blockade immunotherapy through Zn2+ overload triggered pyroptosis by Liming Gong, Yanhong Liu, Jing Feng, Congcong Xiao, Chenfei Liu, Bohan Chen, Liqing Chen, Mingji Jin, Youyan Guan, Zhonggao Gao, Wei Huang

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A novel nanomedicine integrating ferroptosis and photothermal therapy, well-suitable for PD-L1-mediated immune checkpoint blockade by Yujun Bao, Guanghao Li, Siqi Li, Haishui Zhou, Ziqing Yang, Zhiqiang Wang, Rui Yan, Changhong Guo, Yingxue Jin

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PARP inhibition is a modulator of anti-tumor immune response in BRCA-deficient tumors by Anna D. Staniszewska, Joshua Armenia, Matthew King, Chrysiis Michaloglou, Avinash Reddy, Maneesh Singh, Maryann San Martin, Laura Prickett, Zena Wilson, Theresa Proia, Deanna Russell, Morgan Thomas, Oona Delpuech, Mark J. O’Connor, Elisabetta Leo, Helen Angell, Viia Valge-Archer

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Immunosuppressive mechanisms and therapeutic targeting of regulatory T cells in ovarian cancer by Jing Li, Haojun Huang, Renxian Xie, Rongying Yang, Haitao Wang, Li Wan

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iMLGAM: Integrated Machine Learning and Genetic Algorithm‐driven Multiomics analysis for pan‐cancer immunotherapy response prediction by Bicheng Ye, Jun Fan, Lei Xue, Yu Zhuang, Peng Luo, Aimin Jiang, Jiaheng Xie, Qifan Li, Xiaoqing Liang, Jiaxiong Tan, Songyun Zhao, Wenhang Zhou, Chuanli Ren, Haoran Lin, Pengpeng Zhang

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Integrated multi-omics profiling reveals the role of the DNA methylation landscape in shaping biological heterogeneity and clinical behaviour of metastatic melanoma by Andrea Anichini, Francesca P. Caruso, Vincenzo Lagano, Teresa M. R. Noviello, Rossella Tufano, Gabriella Nicolini, Alessandra Molla, Ilaria Bersani, Francesco Sgambelluri, Alessia Covre, Maria F. Lofiego, Sandra Coral, Anna Maria Di Giacomo, Elena Simonetti, Barbara Valeri, Mara Cossa, Filippo Ugolini, Sara Simi, Daniela Massi, Massimo Milione, Andrea Maurichi, Roberto Patuzzo, Mario Santinami, Michele Maio, Michele Ceccarelli, Roberta Mortarini, On behalf of the EPigenetic Immune-oncology Consortium Airc (EPICA) investigators

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Post-translational modifications of immune checkpoints: unlocking new potentials in cancer immunotherapy by Qiongjie Hu, Yueli Shi, Huang Wang, Liuwen Bing, Zhiyong Xu

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Sequentially Activated Smart DNA Nanospheres for Photoimmunotherapy and Immune Checkpoint Blockade by Yu Chen, Yu Guo, Wen Cheng, Jiahao Fan, Jiacheng Li, Jiajia Song, Xiaohai Yang, Kemin Wang, Jin Huang

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PD-L2 act as an independent immune checkpoint in colorectal cancer beyond PD-L1 by Lvyun Zhu, Ying Qu, Junru Yang, Tong Shao, Jingyu Kuang, Chuanyang Liu, Yanhua Qi, Ming Li, Ming Li, Yingying Li, Sujuan Zhang, Jingyang Wang, Yu Liu, Jiali Liu, Yanming Hu, Lingyun Zhu, Tao Hou

Subjects: “…immune checkpoint blockade…”
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Improving the efficacy of cancer immunotherapy by host-defence caerin 1.1 and 1.9 peptides by Quanlan Fu, Yuandong Luo, Junjie Li, Pingping Zhang, Shuxian Tang, Xinyi Song, Jiawei Fu, Mengqi Liu, Rongmi Mo, Ming Wei, Hejie Li, Xiaosong Liu, Tianfang Wang, Guoying Ni

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Spatial characterization of tertiary lymphoid structures as predictive biomarkers for immune checkpoint blockade in head and neck squamous cell carcinoma by Daniel A. Ruiz-Torres, Michael E. Bryan, Shun Hirayama, Ross D. Merkin, Evelyn Luciani, Thomas J. Roberts, Manisha Patel, Jong C. Park, Lori J. Wirth, Peter M. Sadow, Moshe Sade-Feldman, Shannon L. Stott, Daniel L. Faden

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Neighboring Effect‐Initiated Supramolecular Nanocomplex with Sequential Infiltration as Irreversible Apoptosis Inducer for Synergetic Chemo‐Immunotherapy by Mengjie Ye, Junfeng Hu, Linlin Han, Hengbo Zhang, Peng Xue, Yuejun Kang, Shuang Bai, Zhigang Xu

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Co-targeting of VEGFR2 and PD-L1 promotes survival and vasculature normalization in pleural mesothelioma by Sophie Rovers, Jonas Van Audenaerde, Ruben Verloy, Jorrit De Waele, Louize Brants, Christophe Hermans, Ho Wa Lau, Céline Merlin, Maria Möller Ribas, Peter Ponsaerts, Steven Van Laere, Filip Lardon, An Wouters, Scott A. Fisher, Jan van Meerbeeck, Elly Marcq, Evelien Smits

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Efficacy and pharmacodynamic effect of anti-CD73 and anti-PD-L1 monoclonal antibodies in combination with cytotoxic therapy: observations from mouse tumor models by Brajesh P. Kaistha, Gozde Kar, Andreas Dannhorn, Amanda Watkins, Grace Opoku-Ansah, Kristina Ilieva, Stefanie Mullins, Judith Anderton, Elena Galvani, Fabien Garcon, Jean-Martin Lapointe, Lee Brown, James Hair, Tim Slidel, Nadia Luheshi, Kelli Ryan, Elizabeth Hardaker, Simon Dovedi, Rakesh Kumar, Robert W. Wilkinson, Scott A. Hammond, Jim Eyles

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