The usage of personalized scheme of fentanyl administration during coronary artery stenting by D.О. Dziuba

Get full text

Psilocybin-assisted therapy for reducing alcohol intake in patients with alcohol use disorder: protocol for a randomised, double-blinded, placebo-controlled 12-week clinical trial... by Claus Thorn Ekstrøm, Patrick MacDonald Fisher, Gitte Moos Knudsen, Dea Siggaard Stenbæk, Anders Fink-Jensen, Mathias Ebbesen Jensen, Tobias Søgaard Juul

“…Key secondary outcomes are as follows: (1) total alcohol consumption, (2) phosphatidyl-ethanol, an objective biomarker for alcohol, (3) plasma psilocin, the active metabolite, to establish a possible therapeutic range, (4) the acute subjective drug experience as a possible predictor of treatment outcome and (5) neuronal response to alcohol cues and cognitive flexibility within corticostriatal pathways by use of functional MR brain imaging 1-week postdosing.Ethics and dissemination Ethical approval has been obtained from the Committee on Health Research Ethics of the Capital Region of Denmark (H-20043832). …”
Get full text

Association between combined healthy lifestyles and infertility: a cross-sectional study in US reproductive-aged women by Xiaofeng Ye, Xiaoxia Song, Sihang Zhou, Guoqing Chen, Liping Wang

Get full text

Orphan G protein-coupled receptor GPRC5B controls macrophage function by facilitating prostaglandin E receptor 2 signaling by Jeonghyeon Kwon, Haruya Kawase, Kenny Mattonet, Stefan Guenther, Lisa Hahnefeld, Jamal Shamsara, Jan Heering, Michael Kurz, Sina Kirchhofer, Cornelius Krasel, Michaela Ulrich, Margherita Persechino, Sripriya Murthy, Cesare Orlandi, Christian D. Sadik, Gerd Geisslinger, Moritz Bünemann, Peter Kolb, Stefan Offermanns, Nina Wettschureck

Get full text

Enhancing immunotherapy efficacy in colorectal cancer: targeting the FGR-AKT-SP1-DKK1 axis with DCC-2036 (Rebastinib) by Xiguang Chen, Qiting Zeng, Liyang Yin, Bingru Yan, Chen Wu, Jianbo Feng, Ying Wu, Jun He, Wenjun Ding, Jing Zhong, Yingying Shen, Xuyu Zu

Get full text

Sarcomatous tumor with external iliac vein aneurysm: a rare entity by Tushar Kalekar, Neeha Amit Jhala, Reetika Kapoor, Eshan Chetan Durgi, Karishma Krishnani

“…While initial diagnosis relies on duplex ultrasound with color Doppler, additional imaging modalities such as CT venography, real-time venography, and MRI are essential for detailed evaluation. …”
Get full text

Effectiveness and utilization of a cognitive screening program for primary geriatric care by David P. Salmon, Anna Malkina, Melanie L. Johnson, Christina Gigliotti, Emily A. Little, Douglas Galasko

“…Medical records documented discussion of screening results with the patient in 69% of cases (80% if MCI or dementia was detected) and often referral to a specialist (62%), new brain imaging (54%), or change in medication (58%) when screening indicated potential cognitive impairment. …”
Get full text

Analysis of pulmonary sequestration cases, based on the 11-year birth defects surveillance data of Changsha hospitals by Ruobin Xie, Tao-Sha Wang, Yanling Wang, Wei-Dong Wang

“…Some cases have no symptoms in childhood and are misdiagnosed and mistreated because of lung imaging findings in adulthood. Given the scarcity of related literature on PS, this present study aimed to investigate its prevalence, factors affecting survival, and strategies to avoid misdiagnosis and inappropriate treatment in adulthood. …”
Get full text

Solving the choice puzzle: Financial and non-financial stakeholders preferences in corporate disclosures by Oleh Pasko, Li Zhang, Alvina Oriekhova, Nataliia Gerasymenko, Olena Polishchuk

Get full text

Identifying the Thermal Storage Stability of Polymer-Modified Asphalt with Carbon Nanotubes Based on Its Macroperformance and Micromorphology by Xi-yin Liu, Peng Wang, Yu Lu, Tian-tao Zhang, Li-zhi Wang, Tong-fu Wang

“…Meanwhile, a small size of polymer-rich phase and dense network of SBSMA with CNTs were observed in fluorescence microscopy and atomic force microscopy images, thereby exhibiting improved thermal storage stability. …”
Get full text

Evaluation of the relationship between worry and anxiety with the general health status of pregnant women at risk of diagnosing abnormalities by Maryam Hassanzadeh Bashtian, Morvarid Irani, Alireza Afshari-Safavi, Fatemeh Keramati, Roya Ram, Tooba Farazmand

“…They were referred by health centers, midwives, or gynecologists to determine fetal abnormalities according to the national guidelines of Iran for ultrasound scan anomalies. Pregnancy imaging was performed in Bojnurd city between April and December 2023. …”
Get full text

Augmented Reality Navigation System Enhances the Accuracy of Spinal Surgery Pedicle Screw Placement: A Randomized, Multicenter, Parallel‐Controlled Clinical Trial by Yichao Ma, Jiangpeng Wu, Yanlong Dong, Hongmei Tang, Xiaojun Ma

“…ABSTRACT Objective The pedicle screw insertion technique has evolved significantly, and despite the challenges of precise placement, advancements like AR‐based surgical navigation systems now offer enhanced accuracy and safety in spinal surgery by integrating real‐time, high‐resolution imaging with virtual models to aid surgeons. This study aims to evaluate the differences in accuracy between novel AR‐guided pedicle screw insertion and conventional surgery techniques. …”
Get full text

Surgical planning of small intestine neuroendocrine tumors: the concept of mesenteric tumor deposits by Romain L’Huillier, Gilles Poncet, Arnaud Pasquer, Thomas Walter, Catherine Lombard-Bohas, Valérie Hervieu, Bénédicte Cayot, Pierre-Jean Valette, Helen Cheung, Laurent Milot

Get full text

Numbness and Weakness Recovered at a Less Extent in Patients with Lumbar Disc Herniation after Percutaneous Endoscopic Lumbar Discectomy by Yuming Wang, Fuqiang Gao, Haibo Zou

“…Results of the logistic regression analysis showed that the preoperative pain score of SBI (p=0.002; OR: 1.647 (1.199–2.261)) was a relatively independent risk factor for PELD outcomes, and multiplicativity of duration of preoperative symptoms and imaging grade [p=0.004; OR: 1.015 (1.005–1.026)] was a relatively independent risk factor for preoperative presence of numbness and/or weakness. …”
Get full text

Long-term efficacy and safety of alemtuzumab in participants with highly active MS: TOPAZ clinical trial and interim analysis of TREAT-MS real-world study by Tjalf Ziemssen, Ann D. Bass, Bart Van Wijmeersch, Sara Eichau, Stephan Richter, Frank Hoffmann, Nicole M. Armstrong, Magdalena Chirieac, Janete Cunha-Santos, Barry A. Singer

“…Methods: Efficacy outcomes (annualized relapse rate (ARR), change in Expanded Disability Status Scale (EDSS), 6-month confirmed disability worsening/improvement, magnetic resonance imaging), and adverse events (AEs) were examined. …”
Get full text

Unresectable Hepatic Metastasis of Uveal Melanoma: Hepatic Chemosaturation with High-Dose Melphalan—Long-Term Overall Survival Negatively Correlates with Tumor Burden by R. Brüning, M. Tiede, M. Schneider, P. Wohlmuth, H. Weilert, K. Oldhafer, A. Stang

“…Estimates of the overall survival were 0.213 (0.0449, 1) from first imaging (95% confidence interval) to 5 years and 0.793 (0.609, 1) and 0.604 (0.380, 0.960) for 1 and 2 years after chemosaturation, respectively. …”
Get full text

City of Wars: the Representation of Wartime London in Two Novels of the 1940s: James Hanley’s No Directions and Patrick Hamilton’s The Slaves of Solitude by Jean-Christophe Murat

“…No Directions entretient des liens assez forts avec la rhétorique et les images—alors à très la mode—des Poètes de la Nouvelle Apocalypse (New Apocalyptic poetry) ; l’expérimentation formelle et linguistique y est donc omniprésente, frisant même l’artificiel par endroits. …”
Get full text

Electroencephalogram-Based Brain Connectivity Analysis in Prolonged Disorders of Consciousness by Yuzhang Wu, Zhitao Li, Ruowei Qu, Yangang Wang, Zhongzhen Li, Le Wang, Guangrui Zhao, Keke Feng, Yifeng Cheng, Shaoya Yin

“…Participants underwent magnetic resonance imaging (MRI) T1 three-dimensional magnetization with a prepared rapid acquisition gradient echo (3D-T1-MPRAGE) sequence, and video EEG data were collected. …”
Get full text

Snapshots of Pseudomonas aeruginosa SOS response reveal structural requisites for LexA autoproteolysis by Filippo Vascon, Sofia De Felice, Matteo Gasparotto, Stefan T. Huber, Claudio Catalano, Monica Chinellato, Riccardo Mezzetti, Alessandro Grinzato, Francesco Filippini, Lorenzo Maso, Arjen J. Jakobi, Laura Cendron

Get full text

Childhood neurodivergent traits, inflammation and chronic disabling fatigue in adolescence: a longitudinal case–control study by Neil A Harrison, Hugo D Critchley, Jessica Eccles, Kevin A Davies, Lisa Quadt, Rod Bond, Jenny Csecs

Get full text