Local Overexpression of Interleukin-11 in the Central Nervous System Limits Demyelination and Enhances Remyelination by Anurag Maheshwari, Kris Janssens, Jeroen Bogie, Chris Van Den Haute, Tom Struys, Ivo Lambrichts, Veerle Baekelandt, Piet Stinissen, Jerome J. A. Hendriks, Helena Slaets, Niels Hellings

“…When IL-11 expressing LV was therapeutically applied in animals with extensive demyelination, a significant enhancement of remyelination was observed as demonstrated by Luxol Fast Blue staining and electron microscopy imaging. Our results indicate that IL-11 promotes maturation of NG2+ OPCs into myelinating CC1+ OLs and may thus explain the enhanced remyelination. …”
Get full text

Scrotal Skin Metastases Revealing a Prostatic Adenocarcinoma by Idriss Ziani, Zayd El Boukili El Makhoukh, Ahmed Ibrahimi, Omar Bellouki, Jihane Benahmed, Yasmine Laraqui, Fouad Zouidia, Hachem El Sayegh, Lounis Benslimane, Yassine Nouini

“…Bone scintigraphy showed that the cancer has spread to the bones. Imaging studies showed that the cutaneous lesions were limited to the scrotal wall. …”
Get full text

Investigating the Effect of Temperature and Time of the Process of Producing Graphene Quantum Dots by Carbonization on Structural, Microstructural, and Optical Properties by M. Nazari, H. R. Baharvandi, N. Ehsani

“…The microstructure was examined by field emission escanning electron microscopy images. Also, the morphology of the surface and the distance between the planes were investigated by high resolution transmission electron microscopy. …”
Get full text

Correlation between Choroidal Neovascularization Shown by OCT Angiography and Choroidal Thickness in Patients with Chronic Central Serous Chorioretinopathy by Joanna Gołębiewska, Joanna Brydak-Godowska, Joanna Moneta-Wielgoś, Monika Turczyńska, Dariusz Kęcik, Wojciech Hautz

“…OCTA detected CNV more frequently than other imaging modalities. CNV coexisted with irregular PED in all cases. …”
Get full text

Gastroretentive Pulsatile Release Tablets of Lercanidipine HCl: Development, Statistical Optimization, and In Vitro and In Vivo Evaluation by Gagganapalli Santhoshi Reddy, Usha Yogendra Nayak, Praful Balavant Deshpande, Srinivas Mutalik

“…DoE optimization of data revealed FPRTs containing PEO (20% w/w) with coat weight 480 mg were promising systems exhibiting good floating behavior and lag time in drug release. Abdominal X-ray imaging of rabbits after oral administration of the tablets, confirmed the floating behavior and lag time. …”
Get full text

Autism Spectrum Disorder Classification with Interpretability in Children Based on Structural MRI Features Extracted Using Contrastive Variational Autoencoder by Ruimin Ma, Ruitao Xie, Yanlin Wang, Jintao Meng, Yanjie Wei, Yunpeng Cai, Wenhui Xi, Yi Pan

“…With the development of the machine learning and neuroimaging technology, extensive research has been conducted on machine classification of ASD based on structural Magnetic Resonance Imaging (s-MRI). However, most studies involve with datasets where participants’ age are above 5 and lack interpretability. …”
Get full text

Monitoring land changes at an open mine site using remote sensing and multi-spectral indices by Ikram Loukili, Ahmed Laamrani, Mustapha El Ghorfi, Saida El Moutak, Abdessamad ghafiri

“…The study examines spatio-temporal changes in land use and land cover (LULC) within this phosphate mining city to analyze the impacts of mining on agricultural areas, built-up lands, and water bodies over time. A series of images from 1984 to 2021 were processed in to assess patterns of change within the city. …”
Get full text

Endogenous Cushing’s Syndrome with Precocious Puberty in an 8-Year-Old Boy due to a Large Unilateral Adrenal Adenoma by Muhammad Rajib Hossain, Md. Mashiul Alam, Junaid Nabi, Mahzabin Kibria

“…On followup after three months, the patient showed significant clinical improvement and had lost moderate amount of weight and adrenal imaging was found to be normal.…”
Get full text

The Fractal Dimension of Nuclear Chromatin as a Prognostic Factor in Acute Precursor B Lymphoblastic Leukemia by Randall L. Adam, Rosana C. Silva, Fernanda G. Pereira, Neucimar J. Leite, Irene Lorand-Metze, Konradin Metze

“…In 28 patients, gray scale transformed pseudo-3D images of 100 nuclei (May–Grünwald–Giemsa stained bone marrow smears) were analyzed. …”
Get full text

Assessment of the Relationship between Diabetic Retinopathy and Nailfold Capillaries in Type 2 Diabetics with a Noninvasive Method: Nailfold Videocapillaroscopy by Seyit Uyar, Ayşe Balkarlı, Muhammet Kazım Erol, Bayram Yeşil, Abdullah Tokuç, Doğan Durmaz, Süheyla Görar, Ayhan Hilmi Çekin

“…Capillaroscopic changes were found to be correlated with diabetic retinopathy, in particular with longer disease duration in our study. Capillaroscopic imaging could be a useful new technique for assessment of diabetic microvascular changes.…”
Get full text

FutureMS cohort profile: a Scottish multicentre inception cohort study of relapsing-remitting multiple sclerosis by David Hunt, Siddharthan Chandran, Peter Connick, Peter Foley, Patrick K A Kearns, Sergio E Baranzini, Adam D Waldman, Sarah J Martin, Elizabeth Freyer, F J Carod-Artal, Lee Murphy, Amy Stenson, Jessie Chang, Rozanna Meijboom, Elizabeth N York, Yingdi Chen, Christine Weaver, Katarzyna Hafezi, Stacey Thomson, Adil Harroud, Margaret McLeod, Jonathon O'Riordan, Niall J J MacDougall

“…There is, therefore, a need for integrated predictive tools to inform individualised treatment decision making.Participants Established with the aim of addressing this need for individualised predictive tools, FutureMS is a nationally representative, prospective observational cohort study of 440 adults with a new diagnosis of relapsing-remitting MS living in Scotland at the time of diagnosis between May 2016 and March 2019.Findings to date The study aims to explore the pathobiology and determinants of disease heterogeneity in MS and combines detailed clinical phenotyping with imaging, genetic and biomarker metrics of disease activity and progression. …”
Get full text

Surgical Treatment of Double-Layered Lateral Meniscus by Masataka Ota, Hiroshi Takagi, Shin Kato, Fumiyoshi Kawashima, Koji Kanzaki

“…Plain radiography revealed no abnormal findings, whereas magnetic resonance imaging showed high signal in the posterior segment of the lateral meniscus and an increase in its volume. …”
Get full text

Clonal Populations of Amniotic Cells by Dilution and Direct Plating: Evidence for Hidden Diversity by Patricia G. Wilson, Lorna Devkota, Tiffany Payne, Laddie Crisp, Allison Winter, Zhan Wang

“…More than 40 clonal populations were recovered from 4 amniocentesis samples and representative clones were characterized by flow cytometry, conventional assays for differentiation potential, immunofluorescence imaging, and transcript analysis. The results revealed previously unreported diversity among stromal and epithelial cell types and identified unique cell types that could be lost or undetected in mixed cell populations. …”
Get full text

A Hybrid Digital-Signature and Zero-Watermarking Approach for Authentication and Protection of Sensitive Electronic Documents by Omar Tayan, Muhammad N. Kabir, Yasser M. Alginahi

“…Such issues were largely addressed in the literature for images, audio, and video, with only a few papers addressing the challenge of sensitive plain-text media under known constraints. …”
Get full text

Increase of Vascular Endothelial Growth Factor and Decrease of MCP-1 and Some Updated Epidemiology Aspects of Cystic Echinococcosis Human Cases in Calabria Region by Giovanni Matera, Maria Teresa Loria, Cinzia Peronace, Tatiana Catanzariti, Pio Settembre, Aida Giancotti, Angelo G. Lamberti, Giorgio S. Barreca, Luisa Galati, Gessica Dodaro, Maria Mazzitelli, Alessio Strazzulla, Carlo Torti, Angela Quirino, Maria Carla Liberto, Alfredo Focà

“…Echinococcosis diagnosis was based on imaging, serological investigations, and molecular assay. …”
Get full text

Insula Volume and Salience Network Are Associated with Memory Decline in Parkinson Disease: Complementary Analyses of Voxel-Based Morphometry versus Volume of Interest by Yan-Ting Lu, Wen-Neng Chang, Chiung-Chih Chang, Cheng-Hsien Lu, Nai-Ching Chen, Chi-Wei Huang, Wei-Che Lin, Ya-Ting Chang

“…Twenty-three PD-MCI patients were enrolled and underwent cognitive evaluation and 3-dimensional T1-weighted imaging. Voxel-based morphometry (VBM) was used to assess brain-behavior correlations and examine the relationship between insula and memory score. …”
Get full text

Surgical treatment and outcomes in aortic valve endocarditis and perivalvular abscesses by Ellelan Degife, Alyssa Morrison, Syed Bin Usman Mahmood, Sigurdur Ragnarsson, Andrea Amabile, Roland Assi, Prashanth Vallabjoyshula, Arnar Geirsson

“…One quarter of abscesses were not detected on preoperative imaging. Presence of abscess was a significant predictor of operative mortality. …”
Get full text

Supervised contrastive pre-training models for mammography screening by Zhenjie Cao, Zhuo Deng, Zhicheng Yang, Jie Ma, Lan Ma

“…We believe this work is the first to show that supervised contrastive pre-training (SCP) followed by supervised fine-tuning (SF) can outperform the supervised counterpart on these two critical medical imaging tasks.…”
Get full text

Massive Subchorionic Thrombohematoma (Breus’ Mole) Associated with Fetal Growth Restriction, Oligohydramnios, and Intrauterine Fetal Death by Miyuki Miyagi, Tadatsugu Kinjo, Keiko Mekaru, Hayase Nitta, Hitoshi Masamoto, Yoichi Aoki

“…Because MST is rare, it must be considered in the differential diagnosis of parental conditions. Magnetic resonance imaging can be optimal for diagnosing MST when ultrasound diagnosis is difficult.…”
Get full text

A Comparative Study of Dorsal Buccal Mucosa Graft Substitution Urethroplasty by Dorsal Urethrotomy Approach versus Ventral Sagittal Urethrotomy Approach by Mrinal Pahwa, Sanjeev Gupta, Mayank Pahwa, Brig D. K. Jain, Manu Gupta

“…Eighteen out of twenty patients voided well in each group, and postoperative imaging study in these patients showed a good lumen with no evidence of leak or extravasation. …”
Get full text