Generation of IgM+ B cell-deficient Atlantic salmon (Salmo salar) by CRISPR/Cas9-mediated IgM knockout by Mari Raudstein, Ma. Michelle D. Peñaranda, Erik Kjærner-Semb, Søren Grove, H. Craig Morton, Rolf Brudvik Edvardsen

“…Flow cytometry revealed a 78% reduction in IgM+ B cells in peripheral blood, and Western blot analyses showed decreased IgM protein levels in serum. …”
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Mutational Landscape of Bone Marrow CD19 and CD138 Cells in Waldenström Macroglobulinemia (WM) and IgM Monoclonal Gammopathy of Undetermined Significance (IgM MGUS) by Alessandra Trojani, Alessandro Beghini, Luca Emanuele Bossi, Marta Rachele Stefanucci, Cassandra Palumbo, Antonino Greco, Annamaria Frustaci, Barbara Di Camillo, Roberto Cairoli

Subjects: “…IgM monoclonal Gammopathy of undetermined significance…”
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Intracapillary Monoclonal IgM Deposition Concomitant With Cold Agglutinin Disease by Silvia M. Titan, Sandra Herrmann, Nelson Leung, Pingchuan Zhang, Stephen Ansell

“…A kidney biopsy was performed and revealed IgM-kappa monoclonal protein-associated nephropathy with predominantly intracapillary monoclonal IgM deposition injury pattern, a rare form of MGRS, reported for the first time in association with cold agglutinin disease.…”
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Evaluation of a Rapid Kit for Detection of IgM against Leptospira in Human by Mohan Rao, Fairuz Amran, Nadia Aqilla

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Acquired von Willebrand Syndrome in IgM Monoclonal Gammopathy as the Presentation of Lymphoplasmacytic Lymphoma by Zachary Wolfe, Bradley Lash

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Symptomatic Secondary Selective IgM Immunodeficiency in Adult Man with Undiagnosed Celiac Disease by Eli Magen, Viktor Feldman, Mishal Joseph, Hadari Israel

“…Selective IgM immunodeficiency (SIgMID) is a heterogeneous disorder with no known genetic background and may occur as a primary or a secondary condition. …”
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Distinct plasmablast developmental intermediates produce graded expression of IgM secretory transcripts by Evelyn P. Sievert, Marissa C. Franke, Kayla B. Thomas, Yoseop Yoon, Yongsheng Shi, Roger Sciammas

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Diagnostic utility of rapid tests to detect IgG/IgM antibodies against COVID-19 by Pedro Sánchez Frenes, Dayamí García Torres, María de Jesús Sánchez Bouza, Gippsy Mendoza Cartaya, Mavis Portela Sánchez

“…<br /><strong>Objective</strong>: to evaluate the analytical performance of rapid tests to detect IgG/IgM antibodies against COVID-19.<br /><strong>Methods</strong>: descriptive study, carried out with patients admitted to the Héroes de Playa Girón Specialized Ambulatory Center, in Cienfuegos, with a presumptive, probable or confirmed diagnosis of COVID-19 during two periods of time. …”
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Plasma levels of anti phosphocholine IgM antibodies are negatively correlated with bone mineral density in humans by Michela Palmieri, Spyridoula Maraka, Horace J. Spencer, Jeff D. Thostenson, Katherine Dishongh, Micheal Knox, Betty Ussery, Jesse Byrd, Jacqueline K. Kuipers, Sanaz Abedzadeh-Anaraki, Chitharanjan Duvoor, Yuanjie Mao, Lakshmi Menon, James S. Williams, Stavros C. Manolagas, Robert L. Jilka, Elena Ambrogini

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Evaluation the Efficacy of ELISA IgG, IgM and IgA Tests for Diagnosis of Helicobacter pylori by Hogir Mohammed Shukri Saadi, Ali Yahya Saeed

“…The efficacy of three different ELISA tests (IgG, IgM, IgA) was assessed taking culture as a gold standard method. pylori was found in 70.93%, 30.23% and 5.81% by ELISA IgG, IgA and IgM tests respectively. …”
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Clinical Features and Genetic Analysis of 20 Chinese Patients with X-Linked Hyper-IgM Syndrome by Lin-Lin Wang, Wei Zhou, Wei Zhao, Zhi-Qing Tian, Wei-Fan Wang, Xiao-Fang Wang, Tong-Xin Chen

“…X-linked hyper-IgM syndrome (XHIGM) is one type of primary immunodeficiency diseases, resulting from defects in the CD40 ligand/CD40 signaling pathways. …”
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IgG, IgM, and IgA Antinuclear Antibodies in Discoid and Systemic Lupus Erythematosus Patients by Sheridan A. Jost, Lin-Chiang Tseng, Loderick A. Matthews, Rebecca Vasquez, Song Zhang, Kim B. Yancey, Benjamin F. Chong

“…ELISAs showed elevated levels of IgG ANA, IgM ANA, and IgG/IgM ANA ratios in SLE patients compared with DLE and normal patients. …”
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Posterior Reversible Encephalopathy Syndrome with Stroke in Puerperal Woman with High Titer of Anti-Phospholipid IgM Antibody by Hiroto Hirashima, Masahiro Iwamoto, Tadashi Ozawa, Shigeyoshi Kijima, Shigeki Matsubara, Akihide Ohkuchi

“…We suggested that a high titer of anti-phospholipid IgM antibody might be associated with stroke.…”
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Prognostic role of mesangial IgM deposition in IgA nephropathy: a long-term cohort study by Gabriel Stefan, Simona Stancu, Adrian Zugravu, George Terinte-Balcan

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Immunoglobulin M response in largemouth bass (Micropterus salmoides) following ranavirus infection by Zhenyu Huang, Naicheng Liu, Mingyang Xue, Chen Xu, Yuding Fan, Yan Meng, Nan Jiang, Yiqun Li, Wenzhi Liu, Yang He, Yong Zhou

Subjects: “…IgM+ B cells…”
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Lymphoproliferation and hyper-IgM as the first manifestation of activated phosphoinositide 3-kinase δ syndrome: A case report by Mónica Fernandes-Pineda, Andrés F. Zea-Vera

“…We present a case involving a 15-year-old male who displayed an immunological phenotype that bore a striking resemblance to hyper-IgM syndrome. Whole exome sequencing was undertaken to pinpoint the underlying genetic mutation. …”
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Anti-Tick-Bourne Encephalitis IgM Intrathecal Synthesis as a Prediction Marker in Tick-Borne Encephalitis Patients by Piotr Czupryna, Sambor Grygorczuk, Agnieszka Siemieniako-Werszko, Jakub Okrzeja, Justyna Dunaj-Małyszko, Justyna Adamczuk, Sławomir Pancewicz, Joanna Zajkowska, Karolina Narejko, Joanna Oklińska, Gabriela Trojan, Anna Moniuszko-Malinowska

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Biclonal IgD and IgM Plasma Cell Myeloma: A Report of Two Cases and a Literature Review by Zhongchuan W. Chen, Ioanna Kotsikogianni, Jay S. Raval, Christine G. Roth, Marian A. Rollins-Raval

“…Bone marrow biopsy immunohistochemical studies in two cases revealed neoplastic plasma cells coexpressing IgD and IgM, but serum protein electrophoresis identified only the IgM monoclonal paraprotein in both cases. …”
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An X-Linked Hyper-IgM Patient Followed Successfully for 23 Years without Hematopoietic Stem Cell Transplantation by Necil Kutukculer, Neslihan Edeer Karaca, Guzide Aksu, Ayca Aykut, Erhan Pariltay, Ozgur Cogulu

“…In conclusion, diagnostic delay is a clinical problem for patients with CD40LG deficiency, because of low or normal IgM levels, showing that all the hypogammaglobulinemic patients, not only with high serum IgM levels, but also with normal to low IgM levels, have to be examined for CD40LG expression on activated T lymphocytes. …”
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The Coincidence of Newly Diagnosed Type 1 Diabetes Mellitus with IgM Antibody Positivity to Enteroviruses and Respiratory Tract Viruses by Murat Karaoglan, Fahriye Eksi

“…Our study demonstrates the significant association between T1DM and the presence of IgM antibodies against IVB, ECHO7, PIV4, CAV7, and H3N2, and the majority of newly diagnosed T1DM appeared in the fall-winter season. …”
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