A Rare Presentation of Hepatitis A Infection with Extrahepatic Manifestations by Geetika Bhatt, Varrinder S. Sandhu, Charlene K. Mitchell

“…A 34-year-old male presented with sudden onset of left sided facial pain, swelling, and skin rash, with diffuse body pains and muscle weakness, and was found to be positive for hepatitis A immunoglobulin M (IgM). He was initially started on antibiotics for concerns of bacterial parotitis but did not show any improvement. …”
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Coinfection with Rickettsia helvetica and Herpes Simplex Virus 2 in a Young Woman with Meningoencephalitis by Kenneth Nilsson, Katarina Wallménius, Carl Påhlson

“…The bacteria were also isolated in Vero cell culture, and microimmunofluorescence confirmed the development of antibodies against Rickettsia spp. with predominance of IgM reactivity consistent with recent infection. …”
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Severe Hemolytic Anemia Associated with Mild Pneumonia Caused by Mycoplasma pneumonia by Zafer Kurugol, Serife Sebnem Onen, Guldane Koturoglu

“…Diagnosis of M. pneumoniae infection was confirmed by elevated levels of M. pneumoniae IgG and IgM antibodies and a chest X-ray suggestive of atypical pneumonia. …”
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Splenorenal Manifestations of Bartonella henselae Infection in a Pediatric Patient by Taylor Rising, Nicholas Fulton, Pauravi Vasavada

“…Bartonella henselae IgG and IgM titers were positive, consistent with an acute Bartonella henselae infection. …”
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Bing-Neel Syndrome Case Report: A Previously Undocumented IgG Variant with MRI, PET/CT, and PET/MRI Imaging by Daniel Halperin, Simon Hallam, Athar Haroon, Tom Butler, Samir Agrawal

“…Waldenstrom’s macroglobulinaemia is the most commonly reported subtype of lymphoplasmacytic lymphoma (LPL); it is characterised by IgM secretion. Neurological complications are common usually as a result of hyperviscosity. …”
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Study of some parameters of humoral immunity in asthmatic elderly patients by Marisela Pérez Pacareu, Alina González Paredes, Rafael Zamora Puerta, Dayamí García Torres

“…We confirmed irregularities in immunoglobulin G quantification, not in IgA and IgM. <strong><br />Conclusions: </strong>Knowledge about humoral immunity in asthmatic elderly patients allows being more careful in their treatment.…”
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Distinguishable Immunologic Characteristics of COVID-19 Patients with Comorbid Type 2 Diabetes Compared with Nondiabetic Individuals by Ruxing Zhao, Yujing Sun, Yongyuan Zhang, Weili Wang, Shouyu Wang, Chuang Wang, Jinbo Liu, Ling Gao, Zhao Hu, Jianchun Fei, Xinguo Hou, Huizhen Zheng, Li Chen

“…Levels of C reactive protein, immunoglobulin (IgG, IgM, IgA, and IgE), and complements (C3, C4) were detected by rate nephelometry immunoassay. …”
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Perfil clínico, epidemiológico e laboratorial de casos suspeitos de arboviroses durante a emergência do Zika vírus no Brasil by José Henrique Francisco Roma, Rachel Cruz Alves, Ludiele Souza Castro, Márcio José Ferreira, Claudinéia de Araújo, Bruno Moreira Carneiro, Renata Dezengrini Slhessarenko, Juliana Helena Chavez Pavoni, Mariângela Ribeiro Resende

“…Os ensaios sorológicos para Zika mostraram 10,6% de amostras positivas para IgM e 55,8% para IgG. Conclusão: Este estudo fornece o perfil clínico, epidemiológico e laboratorial da emergência do Zika vírus em ambientes de alta endemicidade de dengue. …”
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Seroprevalence of Human Herpesvirus Infections in Newly Diagnosed HIV-Infected Key Populations in Dar es Salaam, Tanzania by Doreen Kamori, Agricola Joachim, Mucho Mizinduko, Godfrey Barabona, Macdonald Mahiti, Upendo Kibwana, Mtebe Majigo, Salim Masoud, Ambele M. Mwandigha, Takamasa Ueno, Elia Mmbaga, Eligius Lyamuya

“…The enzyme-linked immunosorbent assay was used to determine IgG and IgM titers for cytomegalovirus (CMV) and herpes simplex virus (HSV) types 1 and 2. …”
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Association of combined pulmonary fibrosis and emphysema in rheumatoid arthritis with high titer of rheumatoid factor and autoimmunity to the lung by Aiping Ma, Renliang Huang, Jiaxi Guo, Guangdong Wang, Heqing Huang, Xinze Li, Shan Zhong, Yan Huang, Shaowei Lin, Yikai Lin, Qiaomiao Zhou, Susanne Krauss-Etschmann, Frank Petersen, Zhanxiang Wang, Xinhua Yu, Xinhua Yu

“…Multiple logistic analyses were conducted to identify potential risk factors for RA-CPFE development. Patient IgG and IgM autoantibodies to primary human bronchial epithelial cells (HBEC) from healthy donors were assessed using flow cytometry.FindingsAmong the 976 RA patients, 414 (42.4%) developed interstitial lung disease (ILD), with 74 (7.6%) experiencing CPFE. …”
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A Review of the Physiological and Immunological Functions of Biliary Epithelial Cells: Targets for Primary Biliary Cirrhosis, Primary Sclerosing Cholangitis and Drug-induced Ductop... by Chih-Te Wu, Paul A. Davis, VelImir A. Luketic, M. Eric Gershwin

“…BEC transports IgA as well as IgM into bile, synthesizes and secretes various chemokines, cytokines, and expresses adhesion molecules involved in cell interaction and signal transduction. …”
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Congenital toxoplasmosis in infants from chronically infected mothers: report of two cases by Roberta Rassi Almeida, Geovana Batista de Campos, Ana Maria Castro

“…Case description: The mothers had a previous serological diagnosis of toxoplasmosis conducted during prenatal care, with non-reactive (<10 IU/mL) IgM and reactive IgG (>10 IU/mL), and were considered “immune” to the infection. …”
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A Rare Case of Cardiac Recovery after Acute Myocarditis from West Nile Virus Infection: A Review of the Current Literature by KaChon Lei, Wilbur Ji, Bhavana Bhaya, Chowdhury Ahsan

“…He was found to have a positive serum WNV IgM suggestive of a diagnosis of WNV myocarditis. …”
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Molecular Typing of Dengue Virus Circulating in Kolkata, India in 2010 by Arindam Sarkar, Debjani Taraphdar, Shyamalendu Chatterjee

“…All the samples were tested for the detection of IgM antibodies by ELISA method, followed by RT-PCR test for the detection of serotypes. …”
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Laboratory Diagnosis of Mumps in a Partially Immunized Population: The Nova Scotia Experience by TF Hatchette, R Davidson, S Clay, J Pettipas, J LeBlanc, S Sarwal, M Smieja, KR Forward

“…The present study describes the performance characteristics of reverse transcriptase polymerase chain reaction (RT-PCR) on buccal and urine specimens and immunoglobulin M (IgM) serology in this partially immune population.…”
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A customizable multiplex protein microarray for antibody testing and its application for tick-borne and other infectious diseases by Hari Krishnan Krishnamurthy, Vasanth Jayaraman, Karthik Krishna, Tianhao Wang, Kang Bei, Chithra Changalath, Shiny Matilda, Alex J. Rai, Renata Welc-Falęciak, Agnieszka Pawełczyk, Lucas S. Blanton, Aleš Chrdle, Andrea Fořtová, Daniel Růžek, Gheyath K. Nasrallah, Laith J. Abu-Raddadi, Duaa W. Al-Sadeq, Marah Abed Alhakim Abdallah, Daniele Lilleri, Chiara Fornara, Piera D’Angelo, Milena Furione, Maria Söderlund-Venermo, Klaus Hedman, Dimosthenis Chochlakis, Eirini Makridaki, Artemis Ntoula, Anna Psaroulaki, Angélica Escárcega-Ávila, John J. Rajasekaran

“…The microarray improved IgM and IgG sensitivities and specificities of individual microbes when compared with the respective gold standards. …”
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Rare renal proximal tubular dysfunctions in primary biliary cholangitis by Xiaoxiao Shi, Tianchen Guo, Yubing Wen, Wei Ye, Wenling Ye, Ke Zheng, Yan Qin, Xuemei Li, Fengchun Zhang, Limeng Chen

“…Most of them were asymptomatic PBC (7, 63.6%) with a high prevalence of elevated serum immunoglobulin M (IgM, 81.8%) and G (IgG, 54.5%) levels. In the kidney, they had a mean estimated glomerular filtration rate (eGFR) level of 46.54 ± 23.03 ml/min/1.73m2, and 81.8% of them had eGFR below 60 ml/min/1.73m2. …”
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Immunization with a Synthetic Helicobacter pylori Peptide Induces Secretory IgA Antibodies and Protects Mice against Infection by David Espinosa-Ramos, Diana Caballero-Hernández, Ricardo Gomez-Flores, Armando Trejo-Chávez, Luis Jerónimo Pérez-Limón, Myriam Angélica de la Garza-Ramos, Reyes Tamez-Guerra, Patricia Tamez-Guerra, Cristina Rodriguez-Padilla

“…Moreover, immunization correlated with plasma secretory IgA and IgG, whereas infection alone only elicited IgM antibodies. Peptide immunization protected 100% of mice against virulent H. pylori. …”
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Quantifying Changes in the Cellular Thiol-Disulfide Status during Differentiation of B Cells into Antibody-Secreting Plasma Cells by Rosa E. Hansen, Mieko Otsu, Ineke Braakman, Jakob R. Winther

“…The results show that while the global thiol-disulfide state is affected to some extent by the differentiation, steady-state levels of glutathionylated protein thiols are less than 0.3% of the total protein cysteines, even in fully differentiated cells, and the overall protein redox state is not affected until late in differentiation, when large-scale IgM production is ongoing. A general expansion of the ER does not affect global protein redox status until an extensive production of cargo proteins has started.…”
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Liver Infarction in a Patient with HELLP and Probable Anti-phospholipid Syndrome by Cihan Kaya, Hüseyin Cengiz, Murat Ekin, Ammar Kanawati, Levent Yaşar

“…Further, laboratory parameters defined an elevated Cardiolipin IgM antibody (11.59 U/ml). She had a diagnosis of HELLP and probable anti-phospholipid syndrome due to these findings. …”
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