CBP22, a Novel Bacteriocin Isolated from Clostridium butyricum ZJU-F1, Protects against LPS-Induced Intestinal Injury through Maintaining the Tight Junction Complex by Tenghao Wang, Jie Fu, Xiao Xiao, Zeqing Lu, Fengqin Wang, Mingliang Jin, Yizhen Wang, Xin Zong

“…The results showed that pretreatment with CBP22 prevented LPS-induced impairment in epithelial tissues and significantly reduced serum levels of IgG, IgA, IgM, TNF-α, and sIgA. Moreover, CBP22 treatment increased the expression of the zonula occludens and reduced permeability as well as apoptosis in the jejunum in LPS-treated mice. …”
Get full text

The Presence of Antineutrophil Cytoplasmic Antibodies and Antiphospholipid Antibodies in Patients with Severe Acute Respiratory Syndrome Coronavirus 2: A Case-Control Study among S... by Mohammed Shams Aldeen, Musa Logman Masaad, Ayman Azhary, Abdulomez Suliman, Mohammed Ahmed Alziber, Motasim MohammedAhmed, Farag Alla Mohamed Aman, Salahaldeen Ismail, Nadir Abuzeid, Abdualmoniem O. Musa, Samuel Tekle Mengistu, Mohammed Elfatih Hamida

“…To investigate this, we conducted a case-control study which included patients with a positive reverse transcription-polymerase chain reaction (RT-PCR) test of COVID-19 and a control group with negative COVID-19 PCR and antibody (IgG-IgM and IgA nucleoprotein) ELISA results. An indirect immunofluorescence assay using granulocyte biochips (Aesku slides from AESKU DIAGNOSTICS, Germany) was used to detect ANCA (IgG), as well as multiplex ELISA for the detection of antiphospholipid antibodies for all patients with COVID-19 and for the control group. …”
Get full text

Vertical transmission of Severe Acute Respiratory Syndrome Coronavirus 2: A scoping review. by Lemi Belay Tolu, Alex Ezeh, Garumma Tolu Feyissa

“…Five neonates had elevated IgG and IgM but without intrauterine tissue tested. Four neonates had chest imaging suggestive of COVID-19 pneumonia.…”
Get full text

Correlation of Clinical Severity and Laboratory Parameters with Various Serotypes in Dengue Virus: A Hospital-Based Study by Pooja Rao, Achappa Basavaprabhu, Suchitra Shenoy, Nikhil Victor Dsouza, Basavaiah Sridevi Hanaganahalli, Vaman Kulkarni

“…A prospective study was conducted among 106 patients admitted with acute febrile illness having positive NS1 antigen/IgM ELISA. Clinical data were extracted from medical records including demographics, presence of comorbid conditions, clinical presentation, laboratory investigations, and course including length of hospital stay and outcome. …”
Get full text

Smallpox vaccination in a mouse model by S. N. Shchelkunov, A. A. Sergeev, S. A. Pyankov, K. A. Titova, S. N. Yakubitskiy

“…After vaccination (7, 14, 21, 28, 42, and 56 days post inoculation (dpi)), blood samples were collected from the retro-orbital venous sinus; titers of VACV-specific IgM and IgG in the resulting sera were determined by ELISA. …”
Get full text

Serum Levels of IL-33 and Correlation with IL-4, IL-17A, and Hypergammaglobulinemia in Patients with Autoimmune Hepatitis by Ma Liang, Zhang Liwen, Zhuang Yun, Ding Yanbo, Chen Jianping

“…Additionally, the serum levels of IL-33 in AIH patients were correlated positively with markers of hypergammaglobulinemia (IgG, IgM, and IgA) and liver injury (γ-GT/ALP). Also, the serum levels of IL-33 in AIH patients were correlated positively with proinflammatory cytokine levels (IL-17A and IL-4). …”
Get full text

Expression, Purification, and Evaluation of Diagnostic Potential and Immunogenicity of a Recombinant NS3 Protein from All Serotypes of Dengue Virus by Laura Mónica Álvarez-Rodríguez, Angel Ramos-Ligonio, José Luis Rosales-Encina, María Teresa Martínez-Cázares, Aurora Parissi-Crivelli, Aracely López-Monteon

“…The in-house results were in excellent agreement with the commercial kits with κ=0.934±0.064 (95%  CI = 0.808–1.061), and κ=0.872±0.048 (95%  CI = 0.779–0.965) for IgM and IgG, respectively. The agreement between the NS1 antigen detection versus the rNS3 ELISA, κ=0.837±0.066 (95%  CI = 0.708–0.966), was very good. …”
Get full text

Interleukin-1 signaling and CD4+ T cells control B cell recruitment to the lungs in chronic beryllium disease by Joseph M. Gaballa, Caley Valdez, Douglas G. Mack, Faiz Minhajuddin, Masoom Raza, Tabrez A. Mohammad, Allison K. Martin, Andrew Getahun, Charles A. Dinarello, Andrew P. Fontenot, Shaikh M. Atif

“…In BeO-exposed mice, lung B cells down-regulate IgM but showed an increased IgD and CD44 surface expression. …”
Get full text

CLINICAL AND LABORATORY FEATURES OF LYME ARTHRITIS AND ARTHRITIDES OF OTHER ETIOLOGIES IN CHILDREN OF LVIV REGION by Halyna Lytvyn, Natella Basa

“…None of our patients in group 2 and only 1 patient in group 1 (11.1%) had an IgM level <2 IU/ml. Significantly (p=0.02) higher levels of IgG >200 IU/ml were more often found in group 2, where the percentage of such patients was 42.9%, while in group 1, IgG was not detected in any of the patients. …”
Get full text

Interferon-γ and Interleukin-10 Responses during Clinical Malaria Episodes in Infants Aged 0–2 Years Prenatally Exposed to Plasmodium falciparum: Tanzanian Birth Cohort by Boniphace Sylvester, Dinah B. Gasarasi, Said Aboud, Donath Tarimo, Siriel Masawe, Rose Mpembeni, Göte Swedberg

“…Enzyme-linked immunosorbent assay (ELISA) was used to determine levels of IL-10 and IFN-γ in infants and detect IgM in cord blood. Data were analyzed using SPSS version 20. …”
Get full text

Seroprevalence of SARS-CoV-2 virus antibodies and sociodemographic features of pregnant women in Mogadishu, Somalia: a cross-sectional survey study by Maryan Abdullahi Sh. Nur, Hassan Abdullahi Dahie, Nima Abdi Hassan, Bashiru Garba, Jamal Hassan Mohamoud, Najib Isse Dirie, Mohamed Hussein Adam

“…Also, out of the 141 pregnant women who had two children or less, 19.4% were positive for IgG/IgM antibodies. Participants who had close contact with patients with COVID-19 were significantly associated for testing positive with a p value 0.0001. …”
Get full text

Immunological Consequences of Antihelminthic Treatment in Preschool Children Exposed to Urogenital Schistosome Infection by Nadine Rujeni, Norman Nausch, Nicholas Midzi, Graeme J. Cowan, Richard Burchmore, David R. Cavanagh, David W. Taylor, Takafira Mduluza, Francisca Mutapi

“…Treatment augmented antischistosome IgM and IgE responses. The increase in IgE responses directed against adult worm antigens was accompanied by enhanced antigen recognition by sera from the children. …”
Get full text

Measles and Pregnancy: Immunity and Immunization—What Can Be Learned from Observing Complications during an Epidemic Year by Rosalia Ragusa, Armando Platania, Mario Cuccia, Gaetano Zappalà, Gabriele Giorgianni, Placido D’Agati, Maria Alessandra Bellia, Marina Marranzano

“…We have indicated the case as “confirmed” when the IgM was found to be positive with the ELISA method. …”
Get full text

Effects of yeast culture on growth performance, antioxidant capacity, immune function, and intestinal microbiota structure in Simmental beef cattle by Xueqiang Li, Xueqiang Li, Nan An, Nan An, Hui Chen, Hui Chen, Dacheng Liu, Dacheng Liu

“…Furthermore, YC feeding significantly enhanced the immunoglobulin G (IgG), IgA, IgM levels, lysozyme content, alkaline phosphatase activity, as well as the contents of interleukin-1β (IL-1β), IL-6, and interferon-γ in the cattle serum. …”
Get full text

Presence of dengue virus RNA in urine and oral fluid of laboratory-confirmed dengue patients: Implications for wastewater surveillance by Christine Stauber, Leile Camila Jacob-Nascimento, Caroline Grosch, Moisés da Silva Sousa, Moyra M. Portilho, Rosângela O. Anjos, Margo A. Brinton, Uriel Kitron, Mitermayer G. Reis, Guilherme S. Ribeiro

“…Methods: We examined how often DENV RNA is detected in urine and oral fluid from dengue patients confirmed by serum RT-qPCR, NS1 ELISA or IgM seroconversion in Salvador, Brazil. Results: Of 88 confirmed cases, 9.1 % were positive for DENV RNA in urine (7/88) or oral fluid (1/88). …”
Get full text

Isolation and Evaluation of Potential Use of Prebiotics—Utilizing Butyrate-Producing Bacteria in Nibea coibor by Zhongzhen Li, Ngoc Tuan Tran, Ming Zhang, Zhaoxi Li, Wanying Yang, Shuqi Wang, Zhong Hu, Shengkang Li

“…Compared to control, levels of complement C3, complement C4, immunoglobulin M (IgM), transforming growth factor-β (TGF-β), interleukin (IL)-10, IL-1β, and lysozyme (LZM) increased, while malondialdehyde (MDA) decreased in treated groups. …”
Get full text

Production of recombinant norovirus VP1 protein and its antigenic and immunogenic properties by Vladislav A. Lapin, Dmitry V. Novikov, Ekaterina V. Mokhonova, Dmitry A. Melentyev, Maria I. Tsyganova, Dmitry E. Zaitsev, Viktor V. Novikov

“…When evaluating antigenic properties, it was shown that human IgG, IgM, and IgA antibodies interact with recombinant VP1. …”
Get full text

Structure and immunomodulatory activity of Lentinus edodes polysaccharides modified by probiotic fermentation by Jingjing Liang, Meina Zhang, Xiaohan Li, Yuan Yue, Xiaowei Wang, Mengzhen Han, Tianli Yue, Zhouli Wang, Zhenpeng Gao

“…NF-LEP and F-LEP improved immune organ indices, immunoglobulin (IgG and IgM) and cytokines concentrations; restored the antioxidation capacity of liver; and maintained the balance of gut microbiota. …”
Get full text

Herpes Simplex Virus Type 2 (HSV-2) and Cytomegalovirus (CMV) among Women with Macerated Stillbirth: A Cross-Sectional Hospital-Based Study from Mwanza, Tanzania by Helmut A. Nyawale, Elieza Chibwe, Fridolin Mujuni, Lidya Maiga, Albert Silvin, Alda Ester Chongo, Bertrand Msemwa, Vitus Silago, Mtebe Majigo, Doreen Kamori, Stephen E. Mshana, Mariam M. Mirambo

“…A total of 28 (10.04%, 95% CI: 6.8-13.9) tested positive for HSV-2 IgG antibodies with only 4 (1.43%, 95% CL: 0.3-2.8) testing positive for HSV-2 IgM antibodies. HCMV IgG antibodies were detected in 131 (77.98%, 95% CI: 71-84) of 168 women tested. …”
Get full text

Risk of Nipah Virus Seroprevalence in Healthcare Workers: A Systematic Review with Meta-Analysis by Matteo Riccò, Antonio Cascio, Claudio Costantino, Silvia Corrado, Ilaria Zanella, Pasquale Gianluca Giuri, Susanna Esposito

“…Seroprevalence was estimated from seven studies in 0.00% (95%CI 0.00 to 0.10) for IgM-class antibodies and 0.08% (95%CI 0.00 to 0.72) for IgG class-antibodies, but four of the sampled studies did not report any seropositive cases. …”
Get full text