Structure elucidation, immunomodulatory activity, antitumor activity and its molecular mechanism of a novel polysaccharide from Boletus reticulatus Schaeff by Siyuan Su, Xiang Ding, Yiling Hou, Binbin Liu, Zhouhe Du, Junfeng Liu

“…Bioactivity assays indicated that BRS-X displayed a strong proliferative activity in T cells and B cells and promoted the secretion of immunoglobulin G (IgG), IgE, IgD and IgM. In addition, BRS-X could facilitate the proliferation and phagocytosis of RAW264.7 cells and could significantly inhibit the growth of tumors in S180-bearing mice. …”
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CD4 T-Cell-Independent Antibody Response Reduces Enterovirus 71 Lethality in Mice by Decreasing Tissue Viral Loads by Li-Chiu Wang, Chia-Min Kao, Pin Ling, Ih-Jen Su, Tung-Miao Chang, Shun-Hua Chen

“…Infected CD4 T-cell-deficient mice produced virus-specific neutralizing antibodies, IgM and IgG. Moreover, adoptive transfer of the virus-specific antibody produced by infected CD4 T-cell-deficient mice protected B-cell-deficient mice from infection by reducing tissue viral loads. …”
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Evolución clínico-epidemiológica de pacientes con diagnóstico de dengue. Enero-junio 2017 by Carlos García Gómez, Osvaldo Rodríguez Morales, Claudia Tamara Fernández González, María Octavina Rodríguez Roque

“…Se incluyeron todos los pacientes con diagnóstico confirmado de dengue por IgM (N=83).<br /><strong>Resultados</strong>: la media de la edad fue de 42 años. …”
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Blood biomarker dynamics in people with relapsing multiple sclerosis treated with cladribine tablets: results of the 2-year MAGNIFY-MS study by Heinz Wiendl, Frederik Barkhof, Frederik Barkhof, Xavier Montalban, Anat Achiron, Anat Achiron, Tobias Derfuss, Andrew Chan, Suzanne Hodgkinson, Alexandre Prat, Letizia Leocani, Letizia Leocani, Letizia Leocani, Klaus Schmierer, Klaus Schmierer, Finn Sellebjerg, Finn Sellebjerg, Patrick Vermersch, Hulin Jin, Anita Chudecka, Andreas Kloetgen, Dongdong Lin, Lidia Gardner, Nicola De Stefano

“…Assessments included: lymphocyte dynamics, RNA sequencing (B and T cells), intracellular cytokines, serum proteins (immunoglobulins [IgG and IgM], and serum neurofilament light chain [sNfL]). …”
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Distinct clinical outcomes based on multiple serum cytokine and chemokine profiles rather than autoantibody profiles and ultrasound findings in rheumatoid arthritis: a prospective... by Yukitaka Ueki, Tom W J Huizinga, René E M Toes, Shoichi Fukui, Tomoki Origuchi, Takahiro Maeda, Atsushi Kawakami, Tomohiro Koga, Naoki Matsuoka, Toshihiko Hidaka, Naoki Iwamoto, Mami Tamai, Shin-ya Kawashiri, Akitomo Okada, Ayako Nishino, Tamami Yoshitama, Takahisa Suzuki, Toshimasa Shimizu, Shimpei Morimoto, Tomomi Tsuru, Karin A J van Schie, Masahiro Ayano, Remi Sumiyoshi, Yushiro Endo, Tohru Michitsuji, Kaori Furukawa, Masataka Umeda, Nobutaka Eiraku, Hiroaki Hamada

“…Two distinct groups made of four clusters showed a significant difference in IgM-anti-CCP2 positivity. The least absolute shrinkage and selection operator regression of 38 cytokines and chemokines for Clinical Disease Activity Index (CDAI) remission at 12 months resulted in the selection of MIP-1β. …”
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The Impact of the Lactation Period Gut Microbiota of Two Different Beef Cattle Breeds on Spring-Born Calves by Changbo Chen, Yuzhu Sha, Xiaoqiang Zhang, Pingle Lu, Jianyuan Gao, Ting Jiao, Shengguo Zhao

“…Our study showed that during lactation, Pingliang red cattle had significantly higher IL-6 levels than Simmental cattle, while the latter exhibited higher levels of immune factors such as IgG, IgA, IgM, IL-1β, and TNFα. The analysis of the intestinal microbiota of lactating cows found that Pingliang red cattle were rich in <i>Bacteroidetes</i> and <i>Fibrobacteres</i>, while Simmental cattle had a higher proportion of Actinobacteria. …”
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Feeding of dried sweet orange (Citrus sinensis) peel on humoral immune response of broiler chickens by Z. Pourhossein, A. Qotbi, A. Seidavi, V. Laudadio, D. Mazzei, V. Tufarelli

“…Results The DCSP treatments influenced positively total anti-SRBC and IgG titers on days 28 and 42, whereas no differences were found for IgM titer. The anti-NDV titers were not affected by diets; conversely, the anti-AIV titers were different among treatments. …”
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Proceso del cuidado enfermero aplicado en un adulto con insuficiencia respiratoria por COVID-19 by Iris Villasante Montes, Lisbeth Jazmín Espejo Ávila, Mercedes Consuelo Guerra Pacheco

“…Caso clínico: Paciente mujer adulto de 39 años, no tiene antecedentes de enfermedades anteriores, obesa, con IMC 38, resultados de test rápido SARS-CoV-2: Positivo IgM (+) IgG (+), al examen físico presenta P/A: 145/84, FC: 118 X’, FR 38X’, T: 38,8 ºC, SpO2: 88 % (máscara de reservorio a 15 litros), consciente y orientada, deshidratada, con taquipnea y con hipoventilación a la auscultación. …”
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Direct immunofluorescence (DIF) versus immunohistochemical (IHC) staining of complements and immunoglobulins (Ig) in pemphigus group by Deepika Rana, Nita Khurana, Shramana Mandal, Bijay Laxmi Sahoo

“…Materials and Methods: Twenty-six diagnosed cases of Pemphigus were stained by Peroxidase immunohistochemical method using monoclonal antibody to IgG, IgA, IgM, IgG4, C3, C4 d with DAB as chromogen. Pemphigus cases include twenty of pemphigus vulgaris (PV), four cases of pemphigus foliaceous (PF), and two of pemphigus vegetans (Pveg). …”
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Second-hand Smoke Increases Nitric Oxide and Alters the IgE Response in a Murine Model of Allergic Aspergillosis by Brian W. P. Seymour, Janice L. Peake, Kent E. Pinkerton, Viswanath P. Kurup, Laurel J. Gershwin

“…All Af sensitized mice in ambient air (Af + AIR) made elevated levels of IgE, IgG1, IgM, IgG2a and IgA. Af sensitized mice housed in ETS (Af + ETS) made similar levels of immunoglobulins except for IgE that was significantly reduced in the serum and bronchoalveolar lavage (BAL). …”
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Seroprevalence, Associated Factors, and Fetomaternal Outcome in Pregnant Women That Tested Positive to Hepatitis E Antibodies in Nigeria by Valentine Chimezie Okwara, Ikechukwu Innocent Mbachu, Victor Ikechukwu Ndububa, Henry Chima Okpara, Chioma Pauline Mbachu

“…Blood was collected from each of the participants, and the serum was used to determine the presence of hepatitis E immunoglobulin M (IgM) and G (IgG). The data were analysed using SPSS version 23. …”
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Measles Outbreak among Previously Immunized Adult Healthcare Workers, China, 2015 by Zhengyi Zhang, Yuan Zhao, Lili Yang, Changhong Lu, Ying Meng, Xiaoli Guan, Hongjin An, Meizhong Zhang, Wenqin Guo, Bo Shang, Jing Yu

“…Fifty-one patients (85%) tested positive for IgM antibodies against the measles virus and 50 patients (83.3%) tested positive for measles virus RNA. …”
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Digestive Fermentation, Antioxidant Status, and Haemato-Biochemical Indices of Growing Rabbits Fed on Diets Supplemented with Ziziphus spina-christi Leaf by Suha Hashim Abduljawad

“…Significant differnces in serum immunoglobulins were observed between the groups, while the high levels of ZL supplement led to a significant (P<0.05) increase in the serum IgA, IgG, and IgM levels. Antioxidants expressed as T-AOC, GSH-Px, T-SOD, and CAT in the blood of animals fed on diets containing high levels of ZL were significantly higher. …”
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COVID-19 in patients presenting with malaria-like symptoms at a primary healthcare facility in Accra, Ghana. by Issabella Asamoah, Mildred Adusei-Poku, Priscilla Vandyck-Sey, Allen Steele-Dadzie, Atta Senior Kuffour, Albert Turkson, Ivy Asantewaa Asante, Kantanka Addo-Osafo, Quaneeta Mohktar, Bright Adu, Yaw A Afrane, Kwamena W C Sagoe

“…<h4>Conclusion</h4>It may be difficult to use clinical characteristics to distinguish between patients with COVID-19 having malaria-like symptoms. Detection of IgM using RDTs may be useful in predicting CT values for SARS-CoV-2 real-time PCR and therefore transmission.…”
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Dietary Capsaicin Supplementation Mitigates Calving-Induced Stress and Enhances Antioxidant Capacity, Immune Function, and Gut Microbiota in Periparturient Dairy Cows by Hangfan Li, Zibin Wu, Baisheng Yu, Jinyuan Chen, Chuang Yang, Yongqing Guo, Baoli Sun

“…Results showed that capsaicin significantly reduced milk somatic cell count and pro-inflammatory cytokines (TNF-α, IL-1β, and IL-6) while enhancing serum antioxidant enzymes (SOD, GSH-Px, and CAT) and immunoglobulin levels (IgG, IgA, and IgM). Moreover, capsaicin altered gut microbiota composition, increasing the relative abundance of beneficial genera. …”
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HEAL-Dengue: Hospital- based Exploration, Analysis and Learning about Dengue Outcomes (HEAL-D-ALDO) by Aijaz Zeeshan Khan, Omer Sabir, Adnan Hussain Shahid, Muhammad Bilal Basit, Syeda Arzinda Fatima Shah, Qamar Sajad

“…Methodology: A total of 215 patients presenting with characteristic symptoms and NS1 antigen and IgM. Anti Dengue antibodies positivity were included in current study. …”
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Coexistence of Rheumatoid Arthritis, Systemic Lupus Erythematosus, Sjogren Syndrome, Antiphospholipid Syndrome, and Ankylosing Spondylitis by Moshiur Rahman Khasru, Md Abu Bakar Siddiq, Kazi Mohammad Sayeeduzzaman, Tangila Marzen, Abul Khair Mohammad Salek

“…The patient was seropositive for rheumatoid factor (RF), antibodies against cyclic citrullinated peptides (anti-CCP), antinuclear antibody (ANA), anti-Sm antibody, anti-Sjögren’s-syndrome-related antigen A and B (anti-SSA/SSB), antiphospholipid (aPL-IgG/IgM), and HLA B27; however, serum complement (C3 and C4) levels were normal. …”
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Refractory human cytomegalovirus infection without evidence of genetic resistance in the UL-54 and UL-97 genes in a pediatric hematopoietic stem cell transplant recipient: a case r... by Alejandra Pando-Caciano, Ketty Adid Escudero-Ramirez, Jackeline Carol Rodríguez-Torres, Holger Maita-Malpartida, Holger Maita-Malpartida

“…Both the donor and recipient tested positive for anti-CMV IgG and negative for IgM antibodies. Before transplantation, the patient received CMV prophylaxis in the form of intravenous ganciclovir. …”
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Rheumatoid factor isotypes in rheumatoid arthritis diagnosis and prognosis: a systematic review and meta-analysis by Nicola Bizzaro, Franco Franceschini, Maria Infantino, Carlo Selmi, Gian Domenico Sebastiani, Francesca Motta, Davide Giavarina, Boaz Palterer

“…Testing all RF isotypes with latex test or nephelometry allows for the highest sensitivity (68.6%, 95% CI 66.2% to 71.0%); nonetheless, the determination of IgA isotype provides the highest specificity (91.4%, 95% CI 90.8% to 92.0%) and the highest positive likelihood ratio (7.7, 95% CI 5.7 to 10.4). When testing IgM isotype the highest diagnostic OR (21.7, 95% CI 16.1 to 29.3) is reached. …”
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Seroprevalence of Helicobacter pylori in a population of 15 to 35 years old in Mashhad by Mahdieh Khoshakhlagh, Mohammadreza Tarahomi, Fatemeh Asgharian, Arghavan Kamali, Safoora Sa'd Abadi, Kimia Jafarpour, Samaneh Abolbashari, Mojtaba Meshkat, Aida Gholoobi

“…The serum level of IgG, IgM, and IgA H. pylori antibodies was determined using enzyme linked immunosorbent assay (ELISA) method. …”
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