Hemophagocytic lymphohistiocytosis following enteric fever: A rare autopsy case report by Gwendolyn Fernandes, Pooja Mhashete, Pranav Pramod Patwardhan

“…He was also diagnosed with enteric fever (Widal test and Typhi IgM positive) at the start of these episodes. Hemogram during this period revealed persistent pancytopenia. …”
Get full text

Multifunctional Thioredoxin-Like Protein from the Gastrointestinal Parasitic Nematodes Strongyloides ratti and Trichuris suis Affects Mucosal Homeostasis by Dana Ditgen, Emmanuela M. Anandarajah, Jan Hansmann, Dominic Winter, Guido Schramm, Klaus D. Erttmann, Eva Liebau, Norbert W. Brattig

“…The primary antioxidative activity was assured by reduction of insulin and IgM. Further analysis applying an in vitro mucosal 3D-cell culture model revealed that the secreted Trx-lps were able to bind to monocytic and intestinal epithelial cells and induce the time-dependent release of cytokines such as TNF-α, IL-22, and TSLP. …”
Get full text

Myricetin exposure reduces PC differentiation in vitro in primary human B cells by Shabirul Haque, Betty Diamond

“…Myricetin exposure reduced Ig production both IgM and IgG, in culture supernatants at day 5. Myricetin treatment led to augmented BACH2 expression and reduced IRF4, BLIMP1, and XBP1 expression compared to control cultures. …”
Get full text

Extensive VZV Encephalomyelitis without Rash in an Elderly Man by Karen Lynch, Prakhar Agarwal, Anu Paranandi, Susan Hadley, Mithila Vullaganti

“…CSF VZV qualitative PCR was positive and CSF VZV immunofluorescence assay detected IgM antibody, confirming the diagnosis of VZV encephalomyelitis. …”
Get full text

Levamisole/Cocaine Induced Systemic Vasculitis and Immune Complex Glomerulonephritis by Lohit Garg, Sagar Gupta, Abhishek Swami, Ping Zhang

“…Kidney biopsy was consistent with immune mediated glomerulonephritis and showed mesangial proliferation and immune complex deposition consisting of IgG, IgM, and complement. High dose corticosteroids and discontinuing cocaine use resulted in marked improvement in rash, mucocutaneous lesions, and arthritis. …”
Get full text

Immunoinformatic approach to the design of a novel multi-epitope vaccine against Leishmania major fused to human IgG-Fc by Mahmood Fadaie, Zabihollah Shahmoradi, Hossein Khanahmad

“…Immune simulation results showed significant increases in IgM and IgG antibody levels following three vaccinations, along with enhanced activation of B cells, helper T cells, and cytotoxic T lymphocytes. …”
Get full text

Interleukin-1 Receptor-Associated Kinase 4 Deficiency in a Greek Teenager by Panagiota Karananou, Anastasia Alataki, Efimia Papadopoulou-Alataki

“…Her immunological laboratory evaluation revealed low serum IgA and restored in subsequent measurements; normal IgG, IgM, and IgE; and normal serum IgG subclasses. Peripheral blood immunophenotyping by flow cytometry and dihydrorhodamine (DHR) test revealed normal counts. …”
Get full text

Selective Immunoglobulins deficiency in relatives antibody deficiency patient by Yralys Naranjo Herrera, María del Carmen Chávez Alfonso, Valia Concepción Ulloa, Cándido Marcos León Márquez, Grace Alicia De Lara García, Ernesto Gabriel Caraballosa Yero

“…Results: decreased IgA and IgG values were found only in some first-degree relatives and all showed IgM and CD3+CD4+T lymphocyte numbers within normal parameters. …”
Get full text

The Effects of Laurencia caspica Algae Extract on Hemato-Immunological Parameters, Antioxidant Defense, and Resistance against Streptococcus agalactiae in Nile tilapia (Oreochromis... by Majid Khanzadeh, Babak Beikzadeh, Seyed Hossein Hoseinifar

“…Immunological parameters (including Immunoglobulin M [IgM] and complement 3 [C3]) were significantly higher in treated groups compared to control both 25 days and 50 days posttreatment. …”
Get full text

Cernunnos/XLF Deficiency: A Syndromic Primary Immunodeficiency by Funda Erol Çipe, Cigdem Aydogmus, Arzu Babayigit Hocaoglu, Merve Kilic, Gul Demet Kaya, Elif Yilmaz Gulec

“…Because of that she had low IgG and IgA levels, normal IgM level, and absence of B cells in peripheral blood; she was considered as primary immunodeficiency, Nijmegen breakage syndrome. …”
Get full text

Pre-transfusion detection and transfusion therapy of a patient with autoanti-B and cold agglutinin by YANG Linyu, CHEN LI, LI Zhongjun

“…That is, there was specific autoantibody against B antigen, and the antibody property was IgM. No adverse reactions occurred during the infusion of 3 U type O washed red blood cells and the infusion was effective. …”
Get full text

Dengue Outbreak in a Hilly State of Arunachal Pradesh in Northeast India by Siraj A. Khan, Prafulla Dutta, Rashmee Topno, Monika Soni, Jagadish Mahanta

“…Serum samples (n = 164) collected from patients from Health Training and Research Centre General Hospital, Pasighat, were tested for NS1 antigen and IgM antibodies. NS1-positive samples were analyzed by RT-PCR assay and entomological surveys were carried out. …”
Get full text

类风湿关节炎合并干眼症的临床分析

“…【结果】 52例中有干眼自觉症状者12例占23.1%，Schirmer试验阳性者39例(占75.0%)，BUT阳性者48例(占92.3%)，FL阳性者26例(占50.0%)，其中二项以上检查阳性者22例占(42.3%)；IgA、IgM&、IgG、IgE、C3、C4均有不同程度异常;ESR、RF ≥ 25 IU.mL-1 、crp ≥ 5、抗SSA/抗SSB(+)、ANA(+)分别为75%、90.7%、76.9%、9.3%、43.8%。…”
Get full text

B-CD8+ T Cell Interactions in the Anti-Idiotypic Response against a Self-Antibody by Darel Martínez, Amaury Pupo, Lianet Cabrera, Judith Raymond, Nichol E. Holodick, Ana María Hernández

“…P3 is a murine, germline, IgM mAb that recognizes N-glycolylated gangliosides and other self-antigens. …”
Get full text

Seroprevalence to herpesviruses in patients with primary brain gliomas by T. A. Zykova, O. I. Kit, E. E. Rostorguev, E. A. Shevyakova, N. S. Kuznetsova

“…No statistically significant differences in seroprevalence and the presence of markers of acute infection (IgM) were found either in comparison with non-tumor diseases or depending on the malignancy grade. …”
Get full text

Nutritional Status and Immune Functions in Maintenance Hemodialysis Patients by Hayriye Sayarlioglu, Reha Erkoc, Cengiz Demir, Ekrem Dogan, Mehmet Sayarlioglu, Ahmet Faik Oner, Imdat Dilek

“…In all patients serum urea, creatinine, albumin, iron, cholesterol, triglyceride, CRP, IgG, IgM, IgA, CD4, CD8, CD19, CD16-56 lymphocytes were measured. …”
Get full text

Supplemented with Astragalus dregs improves growth performance, immunity, and antioxidant capacity in fattening pigs by Qi Guo, Jiayi Wang, Xuhan Wang, Hongyi Zhang, Jiajiao Xing

“…The immune function factors demonstrated that IgA, IgG, IgM, and anti-inflammatory cytokines IL-10 and IL-22 were significantly increased, meanwhile pro-inflammatory cytokines IL-2 and IL-6 were decreased (p < 0.05).…”
Get full text

Prevention of LPS-Induced Acute Lung Injury in Mice by Progranulin by Zhongliang Guo, Qinchuan Li, Yang Han, Yongjie Liang, Zengguang Xu, Tao Ren

“…Furthermore, administration of PGRN resulted in remarkable reversal of LPS-induced increases in lung permeability as assessed by reductions in total protein, albumin, and IgM in BAL fluid. Consistently, we revealed a significant reduction of histopathology changes of lung in mice received PGRN treatment. …”
Get full text

Hyperacute Rejection of a Living Unrelated Kidney Graft by Dietlind Tittelbach-Helmrich, Dirk Bausch, Oliver Drognitz, Heike Goebel, Christian Schulz-Huotari, Albrecht Kramer-Zucker, Ulrich Theodor Hopt, Przemyslaw Pisarski

“…Pathological examination was consistent with hyperacute rejection. Depositions of IgM or IgG antibodies were not present in pathologic evaluation of the rejected kidney, suggesting that no irregular endothelial specific antibodies had been involved in the rejection. …”
Get full text

A Nonseminomatous Germ Cell Tumor Presenting as a Mixed Cryoglobulinemic Vasculitis by Gabriel Cojuc-Konigsberg, Isabel Natera-Comte, Blanca E. López Graciano, Luis Gerardo Mosqueda López, José Alonso Ávila-Rojo, Braulio Martínez, Juan C. Ramírez-Sandoval

“…An MCS diagnosis was confirmed by the presence of cryoglobulins (6%) with polyclonal IgM and IgG components and biopsy proven leukocytoclastic vasculitis. …”
Get full text