Investigation on the effectiveness of progranulin as a novel predictive biomarker for allergic disorders by Nisreen Waleed Mustafa, Zaid Nabeel Elia, Abeer Mansour Abdel Rasool, Sanaria Fawzi Jarjes, Salam Farid Nawara, Shakhawan Hamid

“…This categorization was confirmed by serological diagnosis by estimating the levels of immunoglobulin E (IgE). Additionally, C-reactive protein (CRP) levels were measured for the detection of inflammation. …”
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The relationship between histamine receptor type 4 gene polymorphism (rs11662595) and response to H1 antihistamine drugs in patients with chronic idiopathic urticaria by Ebrahim Mohammadi, Fakhredin Karimpour, Ramin Lotfi, Fatemeh Zamani, Abbas Aghaei, Rasoul Nasiri Kalmarzi

“…With the consent of the patients, 5 ml of peripheral blood was taken from each patient for DNA extraction (in a CBC tube) and IgE measurement (in a hemolysis tube without anticoagulant). …”
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The Supernatant of Tonsil-Derived Mesenchymal Stem Cell Has Antiallergic Effects in Allergic Rhinitis Mouse Model by In-Su Park, Ji Hye Kim, Jun-Sang Bae, Dong-Kyu Kim, Ji-Hun Mo

“…In an animal study, the T-MSCs-CM-treated group showed significantly reduced allergic symptoms and infiltration of eosinophils and neutrophils in the nasal mucosa, whereas there was no significant difference in total IgE and the OVA-specific IgE level. Additionally, we found that the 10 mg T-MSCs-CM-treated group showed a significantly decreased IL-4 mRNA expression, compared to the (+) Con group. …”
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Cutaneous and Gastrointestinal Symptoms in Two Patients with Systemic Mastocytosis Successfully Treated with Omalizumab by Sofie Lieberoth, Simon Francis Thomsen

“…We present two cases (a 48-year-old woman and a 57-year-old man) with indolent systemic mastocytosis in whom omalizumab (anti-IgE) reduced gastrointestinal and cutaneous symptoms significantly. …”
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Illicium verum Extract and Trans-Anethole Attenuate Ovalbumin-Induced Airway Inflammation via Enhancement of Foxp3+ Regulatory T Cells and Inhibition of Th2 Cytokines in Mice by Yoon-Young Sung, Seung-Hyung Kim, Dong-Seon Kim, Ji-eun Lee, Ho Kyoung Kim

“…We investigated the effects of treatment on airway hyperresponsiveness, IgE production, pulmonary eosinophilic infiltration, immune cell phenotypes, Th2 cytokine production in bronchoalveolar lavage, Th1/Th2 cytokine production in splenocytes, forkhead box protein 3 (Foxp3) expression, and lung histology. …”
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Oral Allergy Syndrome in a Child Provoked by Royal Jelly by Fantini Paola, Delle Donne Pantalea, Calogiuri Gianfranco, Ferrannini Antonio, Vacca Angelo, Nettis Eustachio, Di Leo Elisabetta

“…Moreover, from the results of specific IgE titers versus Compositae pollens, we have argued the possibility that this case of royal jelly allergy could be explained also by the mechanism of cross-reaction with Compositae pollens.…”
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Diabetes Downregulates Allergen-Induced Airway Inflammation in Mice by Vinicius F. Carvalho, Emiliano O. Barreto, Ana Carolina S. Arantes, Magda F. Serra, Tatiana Paula T. Ferreira, Yago A. P. Jannini-Sá, Cory M. Hogaboam, Marco A. Martins, Patrícia M. R. Silva

“…In parallel, reduction of airway hyperreactivity (AHR) to methacholine, mucus production, and serum IgE levels was also noted under diabetic conditions. …”
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Davallia mariesii Moore Improves FcεRI-Mediated Allergic Responses in the Rat Basophilic Leukemia Mast Cell Line RBL-2H3 and Passive Cutaneous Anaphylaxis in Mice by Hyun Ju Do, Tae Woo Oh, Ju Hye Yang, Kwang Il Park, Jin Yeul Ma

“…Lastly, 250–500 mg/kg DRE significantly attenuated the IgE-induced PCA reaction in mice. These findings provide novel information on the molecular mechanisms underlying the antiallergic effects of DRE in FcɛRI-mediated allergic responses.…”
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Case report: Advanced age at transplantation and pre-emptive treatment with dupilumab in DOCK8 deficiency by Sophia Trombello, Sophia Trombello, Andrea Jarisch, Andre Willasch, Eva Rettinger, Julia Fekadu-Siebald, Dirk Holzinger, Dirk Holzinger, Roland Adelmann, Peter Bader, Shahrzad Bakhtiar

“…Typical findings include highly elevated IgE and eosinophilia. Allogeneic hematopoietic stem cell transplantation (alloHSCT) is indicated as the only curative treatment option. …”
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The effect of 4-month cycling trainings performed on elite cyclists on some immunological parameters by Fulya Erantgil, Mehibe Akandere

“…Significant differences were observed in IgA, IgG, and IgE parameters, whereas no significant difference was found in IgM parameter (P lt;0.05). …”
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Omalizumab for Urticarial Vasculitis: Case Report and Review of the Literature by Misbah Nasheela Ghazanfar, Simon Francis Thomsen

“…We describe a male patient with urticarial vasculitis who was treated with omalizumab (anti-IgE) with convincing results and provide a review of previous reports of patients with urticarial vasculitis treated with omalizumab.…”
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Aubergine and Potato Sensitivity with Latex Sensitisation and Oral Allergy Syndrome by A. S. Bansal

“…We describe a case of aubergine allergy in a 9-year-old girl of Anglo-Indian descent who also had sensitivity to potato, coincidental oral allergy syndrome, and latex sensitisation with mild oral symptoms on consuming kiwi fruit. Specific IgE to aubergine was negative, but skin testing was positive to both raw and cooked aubergine. …”
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Lymphocyte Oxidative Stress/Genotoxic Effects Are Related to Serum IgG and IgA Levels in Coke Oven Workers by Meili Gao, Yongfei Li, Aqun Zheng, Xiaochang Xue, Lan Chen, Yu Kong

“…Except for age, alcohol and smoking status, IgM, and IgE, a significant correlation in urinary 1-OHP and other biomarkers in the total population was observed. …”
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Immunological Consequences of Antihelminthic Treatment in Preschool Children Exposed to Urogenital Schistosome Infection by Nadine Rujeni, Norman Nausch, Nicholas Midzi, Graeme J. Cowan, Richard Burchmore, David R. Cavanagh, David W. Taylor, Takafira Mduluza, Francisca Mutapi

“…Treatment augmented antischistosome IgM and IgE responses. The increase in IgE responses directed against adult worm antigens was accompanied by enhanced antigen recognition by sera from the children. …”
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Assessment of immune responses and intestinal flora in BALB/c mice model of wheat food allergy via different sensitization methods by Chenglong Liu, Chen Chen, Xingyu Yan, Shimin Gu, Xin Jia, Wenhui Fu, Xiao Meng, Wentong Xue

“…Results showed that all the three sensitization methods could induce allergic symptoms; increase the serum antibody (total immunoglobulin E (IgE), specific IgE, IgG, IgA) and histamine content; promote the secretion of Th2 cytokines (interleukin (IL)-4, IL-5, IL-13) and inflammatory factors (IL-6, IL-17A, IL-10); and inhibit the production of Th1 cytokines (IFN-γ, IL-2). …”
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The Role of CD40 in Allergic Rhinitis and Airway Remodelling by Ke-Jia Cheng, Min-Li Zhou, Yong-Cai Liu, Chen Wang, Ying-Ying Xu

“…We also used PAS and MT stains to assess tissue remodelling. Results. (1) The OVA-sIgE, IL-4, IL-5, and IL-13 levels in the serum or supernatant of nasal septal membrane of AR mice were significantly higher than control. …”
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免疫调节剂对哮喘患儿血清IL-4及IFN-γ的影响及临床疗效分析

“…所有患儿在治疗前及12个月后检测血清IL-4。IFN-γ。血浆总IgE浓度,测定肺功能。 【结果】 治疗组因哮喘发作需急诊就诊的次数为(1.02 ± 0.92)次,呼吸道感染的次数(1.32 ± 1.03)次,而对照组分别为(2.17 ± 1.52)和(3.78 ± 1.81)次,两组差异有统计学意义(P < 0.05);两组患儿呼吸道感染频率和哮喘再发次数正相关(P < 0.01)。…”
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Assessment of dermal sensitization by nickel salts in a novel humanized TLR-4 mouse model by K. A. Roach, S. E. Anderson, C. Waggy, J. Aldinger, A. B. Stefaniak, J. R. Roberts

“…Mice were euthanized on Day 10, lymph node (LN) cellularity was assessed, LN and spleen cells were phenotyped, and serum was collected to quantify circulating cytokine and IgE levels. In the LLNA, hTLR-4-positive mice of both sexes exhibited enhanced responsivity to nickel. …”
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Adenosine cyclic phosphate with ultrasonic-assisted pectinase extraction alleviated allergic reactions in RBL-2H3 through inhibiting the influx of intracellular Ca2+ by Qiao Bai, Xiaoping Feng, Yu Wang, Chunyu Wu, Ye Liu, Jiao Sun, Tianli Yue, Fangyu Long

“…Moreover, the effect of cAMP on the anti-allergic function of action induced by immunoglobulin E (IgE) and its meschanism was investigated through establishing the sensitized cell model in rat basophilic leukemia (RBL-2H3) cells using dinitrophenylated (DNP)-bovine serum albumin (BSA)-IgE. …”
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Expression of LINC00847 in Peripheral Blood Mononuclear Cells of Children with Asthma and Its Prediction between Asthma Exacerbation and Remission by Jiaying Hu, Zhike Wang, Suzhen Han, Kai Chen

“…The concentration of immunoglobulin E (IgE) and eosinophil count was examined. The serum levels of interleukin-4 (IL-4), interferon-γ (IFN-γ), and IL-17A were determined by the ELISA method. …”
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