Allergic diseases, drug adverse reactions and total immunoglobulin E levels in lupus erythematosus patients by Anna Wozniacka, Anna Sysa-Jedrzejowska, Ewa Robak, Zbigniew Samochocki, Malgorzata Zak-Prelich

“…Background: The association of allergic diseases, drug adverse reactions and elevated total immunoglobulin E (IgE) concentration in systemic lupus erythematosus patients remains controversial. …”
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Three Unrelated Patients of Roma Ethnicity from a Single Center Carrying the Same Deletion in <i>MYD88</i> Gene: A Founder Effect? by Roberta Romano, Francesca Cillo, Laura Grilli, Alessio Ciaccio, Lorenzo Bufalo, Elisabetta Toriello, Antonio De Rosa, Carmen Rosano, Emilia Cirillo, Giancarlo Blasio, Marika Comegna, Carmela Di Domenico, Giuseppe Castaldo, Claudio Pignata, Giuliana Giardino

“…Moreover, being associated with increased Immunoglobulin E (IgE) levels, this condition should be included in the differential diagnosis of Hyper-IgE syndromes.…”
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Human inborn errors of immunity underlying Talaromyces marneffei infections: a multicenter, retrospective cohort study by Huifeng Fan, Zhiyong Yang, Yuhui Wu, Xiulan Lu, Tian Li, Xuyang Lu, Gen Lu, Liming He, Guoping Lu, Li Huang

“…Three cases presented with pan-hypogammaglobulinemia, while three other cases showed heightened levels of IgM. Elevated levels of IgE were detected in five cases, and six cases exhibited decreased T lymphocyte absolute counts. …”
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Changes in and Potential Mechanisms of Circulating IgA+CD27-Class-Switched Memory B Cells in Patients With Allergic Rhinitis by Zheng H, Xu S, Yang R, Jiao WE, Qiao YL, Liu JY, Fan HM, Zhou YT, Ni HF, Chen J, Deng YQ, Chen SM

“…In AR patients, circulating IgA+CD27- class-switched memory B cells were significantly positively correlated with Treg cells, IL-10, and IL-4 and significantly negatively correlated with IFN-γ, total IgE, sIgE, and VAS scores (P < 0.05). After AIT, the number of circulating IgA+CD27- class-switched memory B cells in AR patients was significantly positively correlated with the number of Treg cells and IL-10 and significantly negatively correlated with the VAS score (P < 0.05).Conclusion: The IgA+CD27- class-switched memory cell subset in human peripheral blood may serve as a potential biomarker for evaluating AR symptoms and treatment efficacy. …”
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Plaque Rupture-Induced Myocardial Infarction and Mechanical Circulatory Support in Alpha-Gal Allergy by Sohab S. Radwan, Gauravpal Gill, Amre Ghazzal, Awais Malik, Christopher Barnett

“…Alpha-gal (AG) allergy is an IgE-mediated allergic reaction to galactose-alpha-1,3-galactose found in mammalian meat. …”
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The Bee Sting That Was Not: An Unusual Case of Hymenoptera Anaphylaxis Averted in a Patient Treated with Omalizumab for Asthma by Evelyn M. Slaughter, Nathan Boyer, Steven Bennett

“…This paper presents a case of hymenoptera venom anaphylaxis averted by omalizumab, a monoclonal antibody to IgE antibody. This case suggests a novel and unintentional effect of this therapy. …”
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Intravenous Immunoglobulins: Mode of Action and Indications in Autoimmune and Inflammatory Dermatoses by Lyubomir A. Dourmishev, Dimitrina V. Guleva, Ljubka G. Miteva

“…Intravenous immunoglobulins (IVIGs), a mixture of variable amounts of proteins (albumin, IgG, IgM, IgA, and IgE antibodies), as well as salt, sugar, solvents, and detergents, are successfully used to treat a variety of dermatological disorders. …”
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Kimura Disease Manifesting as Synchronous Bilateral Parotid Swelling in a Young Middle-Eastern Patient by Fatemah Faras, Fawaz Abo-Alhassan, Khalid Al-Sebeih, Jassem Bastaki

“…Characteristic features of the disease include, but not limited to, painless subcutaneous head and neck swelling, blood and tissue eosinophilia, and markedly elevated immunoglobulin E (IgE) levels. Herein, we report a rare case of Kimura disease manifesting as synchronous bilateral parotid swelling of 12 years duration in a 33-year-old Middle-Eastern man. …”
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Pathogenesis of Chronic Urticaria: An Overview by Sanjiv Jain

“…It is also probable that mast cells are involved in the pathogenesis through mechanisms that extend beyond high affinity IgE receptor stimulation. An increasing recognition of chronic urticaria as an immune mediated inflammatory disorder related to altered cytokine-chemokine network consequent to immune dysregulation resulting from disturbed innate immunity is emerging as yet another pathogenic explanation. …”
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The Role of Immune Defects and Colonization of Staphylococcus aureus in the Pathogenesis of Atopic Dermatitis by Danuta Nowicka, Ewelina Grywalska

“…Moreover, anti-S. aureus-specific IgE was identified and measured in patients with AD, revealing that its level corresponds to the severity of the disease. …”
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Acute Eosinophilic Ascites in a Middle-Aged Man by Fadi Bleibel, Keith Fragoza, Garrey T. Faller

“…Initial work-up demonstrated severe peripheral blood eosinophilia, normal liver function tests, thickening of the stomach and small bowel wall, and elevated serum IgE. Upper endoscopy and extensive testing for malignancy and parasitic infections failed to establish a diagnosis. …”
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Distinguishable Immunologic Characteristics of COVID-19 Patients with Comorbid Type 2 Diabetes Compared with Nondiabetic Individuals by Ruxing Zhao, Yujing Sun, Yongyuan Zhang, Weili Wang, Shouyu Wang, Chuang Wang, Jinbo Liu, Ling Gao, Zhao Hu, Jianchun Fei, Xinguo Hou, Huizhen Zheng, Li Chen

“…Levels of C reactive protein, immunoglobulin (IgG, IgM, IgA, and IgE), and complements (C3, C4) were detected by rate nephelometry immunoassay. …”
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Pruritic Vesicular Eruption on the Lower Legs in a Diabetic Female by Hassan Riad, Hamda Al Ansari, Khaled Mansour, Haya Al Mannai, Hussein Al Sada, Samya Abu Shaikha, Sharifa Al Dosari

“…CBC showed microcytic, hypochromic anemia. Serum zinc, folate, IgE, TSH and T4 were all within normal ranges. Biopsy showed epidermal separation secondary to keratinocyte necrosis and minimal monocytic, perivascular infiltrate. …”
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Comparison of Effects of Smoking and Smokeless Tobacco “Maras Powder” Use on Humoral Immune System Parameters by Murat Aral, Hasan Cetin Ekerbicer, Mustafa Celik, Pınar Ciragil, Mustafa Gul

“…The IgM levels of both groups were significantly lower compared to the control group (P<.05). Nonetheless, the IgE levels of Maras powder group and smoking group were found to be remarkably higher compared to the control group (P<.01). …”
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Significance of Persistent Inflammation in Respiratory Disorders Induced by Nanoparticles by Yasuo Morimoto, Hiroto Izumi, Etsushi Kuroda

“…In allergic responses, nanoparticles act as Th2 adjuvants to activate Th2 immune responses such as activation of eosinophil and induction of IgE. Taken together, the presence of persistent inflammation may contribute to the pathogenesis of a variety of diseases induced by nanomaterials.…”
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IL-1β and Allergy: Focusing on Its Role in Allergic Rhinitis by Han-Rui Wang, Shi-Zhuang Wei, Xiao-Yu Song, Yao Wang, Wen-Bin Zhang, Chao Ren, Ya-Kui Mou, Xi-Cheng Song

“…Allergic rhinitis (AR) is a chronic upper airway immune-inflammation response mediated by immunoglobulin E (IgE) to allergens and can seriously affect the quality of life and work efficiency. …”
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FPIES: Reviewing the Management of Food Protein-Induced Enterocolitis Syndrome by Neha Khanna, Kirtika Patel

“…FPIES is a complex form of non-IgE mediated food allergy. More awareness and knowledge of the condition are required to prevent misdiagnosis. …”
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Angelica acutiloba Kitagawa Extract Attenuates DSS-Induced Murine Colitis by Jong-Chan Jang, Kang Min Lee, Seong-Gyu Ko

“…In the isolated serum, IgE levels were downregulated. Collectively, these findings indicate the therapeutic potentials of AAK as an effective complementary or alternative modality for the treatment of ulcerative colitis.…”
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The impact of atopy on the clinical characteristics of mycoplasma pneumoniae pneumonia in pediatric patients by Yujie Qin, Yuxia Yang, Junxiang Li, Jun Guan

“…Eosinophil count, lactate dehydrogenase and IgE levels were higher in the atopic group than in the non-atopic group. …”
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12/15-Lipoxygenase Is an Interleukin-13 and Interferon-γ Counterregulated-Mediator of Allergic Airway Inflammation by Alexa R. Lindley, Margaret Crapster-Pregont, Yanjun Liu, Douglas A. Kuperman

“…Interleukin-13 augmented and interferon-γ inhibited allergic airway inflammation independently of systemic IgE and mucosal IgA responses but in association with counterregulation of 12/15-lipoxygenase. …”
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