Allergen sensitization patterns: Allergic rhinitis with multimorbidity versus alone—A real‐world study by Ya‐Ting Li, Qi‐Qing Ye, Ya‐Xin Lu, Ke‐Xin Yang, Ping‐Ping Zhang, Chang Chen, Min Zhou, Pei‐Ying Feng, Zhuang‐Gui Chen

“…Allergic multimorbidity often involves polysensitization, where allergen‐specific immunoglobulin E (IgE) plays a significant role. Objective This study aims to explore differences in allergen IgE sensitization patterns between AR alone and AR multimorbidity. …”
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Efficacy and safety of sublingual immunotherapy using a combination of Dermatophagoides pteronyssinus and Blomia tropicalis extracts in patients with allergic rhinitis: A randomize... by Priscilla Rios Cordeiro Macedo, MD, MSc, Priscila Moraes, MD, Luísa Karla Arruda, MD, PhD, Fábio Fernandes Morato Castro, MD, PhD, Jorge Kalil, MD, PhD, Clóvis Eduardo Santos Galvão, MD, PhD

“…Total serum IgE, serum specific IgE, and IgG4 levels for Der p 1 and Blo t were assessed at baseline and, 6 and 12 months after treatment. …”
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Intratonsillar Immunotherapy: A Convenient and Effective Alternative to Subcutaneous Immunotherapy for Allergic Rhinitis by Tian Gu, Wei Zhang, Lu Tan, Rong Xiang, Peiqiang Liu, Jingyu Huang, Qin Deng, Yuqin Deng, Zezhang Tao, Shiming Chen, Yu Xu

“…Prior to clinical trials, we analyzed tonsil samples from human subjects to assess immune responses, measuring interleukin-4 (IL-4), IL-21, total IgE (tIgE), and allergen-specific IgE concentrations using ELISA and BioIC. …”
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RETRACTED ARTICLE: Clinical and immuno-proteomic approach on Lantana camara pollen allergy—a major health hazard by Kavita Ghosal, Bodhisattwa Saha, Swati Gupta Bhattacharya

“…Five IgE reactive bands/zones were observed in 1D blot which resolved to 12 allergo-reactive spots in the 2D blot. …”
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Clinical Response Predictive Model for Omalizumab in Moderate-to-Severe Asthma Patients by Ruiqi Qian, Lingyi Yang, Xurui Shen, Cheng Chen, Jianan Huang, Xiuqin Zhang, Cuiping Fu

“…The serum level of total IgE increased significantly after injection of omalizumab, while blood eosinophils count decreased significantly from baseline. …”
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Selected allergic diseases of the gastrointestinal tract by Andrzej Kuźmiński, Michał Przybyszewski, Małgorzata Graczyk, Magdalena Żbikowska-Götz, Natalia Sokołowska-Ukleja, Alina Tomaszewska, Zbigniew Bartuzi

“…Allergic reactions of the gastrointestinal tract may be IgE-independent (oral anaphylaxis syndrome, acute gastrointestinal reactions), mixed (eosinophilic gastrointestinal disorders), or IgE-independent (food-induced enterocolitis, proctitis, or enteropathy). …”
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Th2 cells and cytokine networks in allergic inflammation of the lung by Anthony J. Coyle, Shogo Tsuyuki

“…The cytokines released from Th2 and Th2-like cells are likely to be central to the pathophysiolgy of asthma and allergy, contributing to aberrant IgE production, eosinophilia and, perhaps, mucosal susceptibility to viral infection. …”
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Cow milk αs1-casein induces allergic responses in a mouse model of atopy by Guangyu Wang, Xiaofeng Yu, Yanjun Cong, Linfeng Li

“…The levels of specific IgE, mast cell proteinase, histamine and cytokines in sensitized mice were determined, and the clinical and pathological observation were evaluated. …”
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The inhibitory effect of anti-allergic agent suplatast tosilate (IPD–1151T) on methacholine- and allergen-induced bronchoconstriction in sensitized mice by Kazuhito Asano, Tetsuya Mizutani, Toshikazu Shimane, Masataka Hisano, Tadashi Hisamitsu, Harumi Suzaki

“…We also examined the effect of IPD-1151T on IgE production in response to DNP-KLH immunization. …”
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Multi-biofluid metabolomics analysis of allergic respiratory rhinitis and asthma in early childhood by Chih-Yung Chiu, MD, PhD, Meng-Han Chiang, MS, Chieh-Ni Kuo, BS, Mei-Ling Cheng, PhD, Gigin Lin, MD, PhD

“…Among them, blood isovaleric acid correlated positively with stool IgE levels in rhinitis, while stool butyric acid and acetic acid in asthma exhibited strong negative correlations with total serum and mite allergen-specific IgE levels (P < 0.01). …”
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Serum Periostin as a Potential Biomarker in the Evaluation of Allergic Rhinitis: A Pilot Study by Zhu XJ, Lu MP, Chen RX, Mao ZF, Yang YF, Han J, Cheng L

“…Participants underwent examinations to assess serum levels of total IgE (tIgE), specific IgE (sIgE), periostin, and remodeling-related factors, as well as fractional exhaled nitric oxide (FeNO) and fractional nasal nitric oxide (FnNO). …”
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Investigation of gut microbiota in pediatric patients with peanut allergy in outpatient settings by Shouming Li, Jingyi Huang, Yunyun Xie, Di Wang, Xin Tan, Yufan Wang

“…The PA group was defined by a positive reaction to peanut-specific IgE tests, while the Ctl group tested negative for peanut IgE and had no history of allergies. …”
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Association of LPCAT1-rs8352 genetic variant with susceptibility and severity of pediatric bronchial asthma: a case-control study by Khalid M. Mohany, Yasser Gamal, Yaser F. Abdel Raheem

“…ECP, hs-CRP, and total IgE serum levels were measured using their corresponding ELISA kits. …”
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A Case of Fish Sausage Anaphylaxis Induced by Epicutaneous Sensitization to Carmine Contained in Eyeshadows: The Effect of Chelation on Carmine Allergy by Maiko Yamaura, Yuriko Iwahashi, Eri Hashimoto, Jun Miura, Yuri Murayama, Sachiko Koshikawa, Naoko Inomata

“…SPT was also positive for carmine. In IgE-immunoblotting using the eyeshadow and fish sausage, the patient serum IgE was bound to three protein bands at approximately 86, 114, and 130 kDa. …”
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Gender-Related Effects of Sex Steroids on Histamine Release and FcεRI Expression in Rat Peritoneal Mast Cells by Samira Muñoz-Cruz, Yolanda Mendoza-Rodríguez, Karen E. Nava-Castro, Lilián Yepez-Mulia, Jorge Morales-Montor

“…In addition to the well-characterized IgE/FcεRI-mediated degranulation, a variety of biological substances can induce MCs activation and release of their granule content. …”
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2 型固有免疫细胞在过敏性及非过敏性哮喘中的临床意义 2型固有免疫细胞在过敏性及非过敏性哮喘中的临床意义 by 曾智敏, 谭卫平, 黄鑫炎, 刘杨丽, 李佩文, 付清玲, 郭禹标

“…【方法】研究对象来自我院2017年6月至2018年1月的过敏性和非过敏性哮喘患者，收集相 应临床基线资料并评估病情、进行血常规、肺功能等检查；应用流式细胞术检测外周血ILC2；通过ELISA和多因子检 测分别测定总IgE及sIgE和Th2型细胞因子。【结果】哮喘（Asthma）组的ILC2比例和计数与嗜酸性粒细胞（EOS）计 数及sIgE 正相关（r=0.37，0.32，0.56，0.57；P<0.01~=0.04）；过敏性哮喘（AA）组的ILC2 比例和计数为0.04（0.03~ 0.11）%和338（255~778）cells/mL，均高于非过敏性哮喘（NAA）组的0.01（0.01~0.02）%及89（0~169）cells/mL （P<0.01）；中/重度患者ILC2比例为（0.10±0.08）%，高于间歇/轻度患者的（0.04±0.01）%（P=0.04）；AA组中ILC2比例 和计数与FEV1/FVC呈负相关（r=-0.61，-0.56；P…”
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中国华南地区局部变应性鼻炎患者的临床特征

“…血清及鼻腔分泌物,并检测血清及鼻腔分泌物中4种变应原特异性IgE水平,比较LAR在发病情况?病史?相关症状评分?变应原等方面与变应性鼻炎(AR)?非变应性鼻炎(NAR)的异同点?…”
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Atypical Presentation of Kimura’s Disease in a Male Patient: A Case Report and Review of Literature by Zahra A. Natsha, Islam A. Hamarsheh, Rawan S. Utt, Bassam Abu Alrob, Adnan A. Wahdan

“…It primarily affects the head and neck region, presenting as deep subcutaneous masses, and is often accompanied by triad regional lymphadenopathy, salivary gland involvement, and high serum immunoglobulin E (IgE) levels. Here, we report the second documented case of KD in Palestine diagnosed in a 28-year-old male patient who presented with lymphadenopathy and increased serum immunoglobulin E and G (IgE and IgG) associated with intermittent abdominal pain, generalised fatigue, hepatomegaly, cardiomyopathy, reactive airway disease, peripheral vasculopathy, peripheral neuropathy, and focal segmental glomerulosclerosis. …”
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Asthma in Children and Adults: A Shared Biological and Molecular Basis by Paolo M Renzi

“…Eosinophilia and increased immunoglobulin (Ig) E levels are present at every age except in young infants. …”
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Kimura disease: A rare presentation in the rheumatology clinic by Malay Kumar, Arun Hegde, Gunjan Dwivedi, Prashant Sengupta, Kovilapu Uday Bhanu

“…Blood and tissue eosinophilia, and elevated immunoglobulin E (IgE) levels, are common associations. Characteristic histopathological findings of biopsy specimens obtained from the subcutaneous swellings or lymph nodes include eosinophilic infiltrates, follicular hyperplasia, and proliferation of postcapillary venules. …”
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